Bumetanide combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 9/1/2005 78 Male 1/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Skin Lesion Other Serious 66 Male 180 lb 1/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 1/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Syncope Hospitalization 10/14/2005 63 Male 359 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 78 Male 2/13/2006 Netherlands
Primary
Secondary
Concomitant
Libido Decreased 12/1/2005 Male 2/27/2006 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Death 62 Male 2/22/2006 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/14/2005 83 Male 210 lb 12/21/2005 Consumer United States
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 5/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 5/12/2006 Physician Netherlands
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Ventricular Arrhythmia Death 76 Male 161 lb 7/11/2006 Other Health Professional Netherlands
Primary
Concomitant
Tremor Other Serious 6/10/2006 58 Female 198 lb 8/16/2006 Physician Belgium
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 8/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/18/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 6/19/2006 76 Male 161 lb 9/19/2006 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/21/2006 81 Female 10/27/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 8/25/2006 Female 254 lb 10/30/2006 United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 6/13/2006 63 Female 254 lb 11/17/2006 Physician Belgium
Primary
Concomitant
Muscular Weakness Hospitalization 6/13/2006 63 Female 254 lb 11/30/2006 Physician Belgium
Primary
Concomitant
Hepatitis Other Serious 12/4/2006 78 Male 154 lb 1/11/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/9/2007 80 Male 234 lb 1/12/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/11/2007 80 Male 219 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/9/2007 79 Female 4/4/2007 Physician
Primary
Secondary
Concomitant
Pain Disability Male 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/9/2007 79 Female 4/7/2007 United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 12/1/2006 68 Female 165 lb 4/11/2007 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Hospitalization 3/24/2007 75 Male 4/25/2007 United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 4/26/2007 United Kingdom
Primary
Concomitant
Neuropathy Peripheral 9/27/2006 48 Female 10/23/2006 Physician United States
Primary
Secondary
Concomitant
Pain Disability 2/14/2007 Male 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 5/31/2007 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/13/2007 64 Female 6/28/2007 Physician
Primary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/1997 Female 7/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Polymyositis Hospitalization 12/1/2006 77 Male 7/20/2007 Physician Norway
Primary
Concomitant
Vomiting Hospitalization 6/24/2007 63 Male 7/25/2007 Norway
Primary
Concomitant
Vomiting Other Serious 7/20/2007 Male 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Urobilin Urine Present Hospitalization 6/24/2007 63 Male 8/6/2007 Other Health Professional Norway
Primary
Concomitant
Rhabdomyolysis Other Serious 5/16/1997 69 Female 8/30/2007 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 Male 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 8/10/2007 Female 172 lb 10/4/2007 Other Health Professional Netherlands
Primary
Concomitant
Insomnia Death 3/20/2007 71 Male 10/26/2007 Consumer Netherlands
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 11/21/2005 80 Male 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Wound Necrosis Life Threatening 4/2/2006 Female 331 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 9/20/2007 73 Female 3/4/2008 Pharmacist United States
Primary
Concomitant
Jaundice Hospitalization 2/28/2008 76 Male 265 lb 3/19/2008 Consumer United Kingdom
Primary
Concomitant
Skin Necrosis Life Threatening 4/2/2006 Female 331 lb 3/28/2008 Consumer
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 68 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 80 Male 4/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 11/10/2007 Male 5/23/2008 Other Health Professional France
Primary
Secondary
Gallbladder Cancer Life Threatening 4/30/2008 Male 192 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 6/15/2008 63 Female 7/2/2008 United Kingdom
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 7/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 9/12/2007 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Raynaud's Phenomenon Disability 5/10/2008 9/8/2008 Consumer United Kingdom
Primary
Concomitant
Injection Site Pain 1/1/2007 Male 230 lb 9/12/2008 United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/1/2006 73 Male 9/22/2008 Physician Norway
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 10/2/2008 Consumer United States
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 8/1/2008 Female 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 10/17/2008
Primary
Concomitant
Respiratory Disorder Disability 3/1/2008 79 Female 183 lb 10/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/1/2005 70 Male 11/6/2008 Physician Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2007 34 Female 11/18/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2005 70 Male 11/26/2008 Physician Norway
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 12/10/2008 Consumer United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 172 lb 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Localised Infection Hospitalization 8/1/2007 Male 301 lb 12/22/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/18/2008 81 Female 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Haemorrhage Hospitalization 10/20/2007 Female 12/26/2008 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious Female 1/27/2009 Consumer Switzerland
Primary
Concomitant
Pericarditis Constrictive Life Threatening 4/1/2008 68 Female 2/16/2009 Consumer Netherlands
Primary
Concomitant
Pericarditis Constrictive Life Threatening 4/1/2008 68 Female 2/23/2009 Consumer Netherlands
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 172 lb 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vasodilatation Hospitalization 5/26/2006 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 12/1/2008 60 Male 4/3/2009 United Kingdom
Primary
Concomitant
Sensory Disturbance Other Serious 11/17/2008 80 Male 4/17/2009 Physician
Primary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 5/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 5/23/2007 81 Female 4/27/2009
Primary
Secondary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 4/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/16/2007 64 Female 128 lb 5/1/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/1/2009 84 Female 163 lb 5/18/2009 Physician Brazil
Primary
Concomitant
Vasodilation Procedure Hospitalization 5/26/2006 51 5/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 2/10/2009 60 Female 300 lb 6/11/2009 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Disability 1/1/2006 73 Male 7/15/2009 Norway
Primary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 9/12/2007 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death 91 Female 8/3/2009 Consumer United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Artery Occlusion Other Serious 1/1/2002 Female 8/4/2009 Consumer United States
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 91 Female 8/6/2009 United Kingdom
Primary
Concomitant
Urosepsis Death 91 Female 8/19/2009 Consumer United Kingdom
Primary
Concomitant
Flushing 2/2/2009 Male 8/22/2009 United States
Primary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Urosepsis Death 91 Female 8/20/2009 United Kingdom
Primary
Concomitant
Renal Artery Occlusion Other Serious 7/1/2000 Female 8/26/2009 Physician United States
Primary
Concomitant
Urosepsis Death 91 Female 9/4/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/8/2009 60 Female 9/9/2009 Physician France
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 9/16/2009 United Kingdom
Primary
Concomitant
Ill-defined Disorder 1/5/2009 62 Female 200 lb 10/2/2009 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 9/4/2009 42 Male 9/29/2009 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 10/8/2009 United Kingdom
Primary
Concomitant
Thrombin Time Prolonged Other Serious 80 Female 10/12/2009 Physician Netherlands
Primary
Concomitant
Sudden Death Death 9/4/2009 42 Male 10/14/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Female 10/18/2009 United States
Primary
Concomitant
Skin Ulcer Life Threatening 2/4/2006 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 3/1/2008 79 Female 10/23/2009 United Kingdom
Primary
Concomitant
Lethargy Hospitalization 11/21/2008 55 Female 229 lb 10/30/2009 Physician United States
Primary
Secondary
Concomitant
Skin Fibrosis Disability 4/1/2006 38 Female 143 lb 11/2/2009 Denmark
Primary
Concomitant
Walking Aid User Hospitalization 7/1/2007 64 Female 124 lb 11/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Social Problem Hospitalization Female 11/3/2009 Lawyer United States
Primary
Concomitant
Tremor Other Serious 9/29/2009 Male 215 lb 11/13/2009 Physician United States
Primary
Concomitant
Aplastic Anaemia Disability 5/23/2007 81 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 81 Female 12/7/2009 United Kingdom
Primary
Concomitant
Off Label Use Other Serious 7/27/2006 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/1/2008 79 Female 183 lb 12/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/18/2008 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 81 Female 12/21/2009 United Kingdom
Primary
Concomitant

Drug Data