Hydromorphone Hcl combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Constipation Required Intervention 8/1/2006 80 Male 175 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 55 Male 12/13/2006 Pharmacist United States
Primary
Concomitant
Femoral Neck Fracture Hospitalization 3/1/2004 Female 2/2/2007 Other Health Professional Germany
Primary
Concomitant
Hypotension Hospitalization 11/5/2006 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/3/2007 66 Male 185 lb 12/6/2007 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2007 Male 7/10/2008 Other Health Professional United States
Primary
Concomitant
Hypocalcaemia Hospitalization 9/14/2008 Male 10/3/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 10/9/2008 72 Female 10/20/2008 Pharmacist United States
Primary
Concomitant
Death Death Female 260 lb 12/16/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/22/2009 Consumer Austria
Primary
Concomitant
Respiratory Failure Hospitalization Female 260 lb 1/29/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/30/2009 Physician Austria
Primary
Concomitant
Sepsis Hospitalization 61 Female 2/27/2009 Other Health Professional Canada
Primary
Concomitant
Sepsis Hospitalization 61 Female 3/4/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 3/5/2009 52 Male 206 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 185 lb 3/20/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/1/2009 Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/8/2009 Male 187 lb 4/3/2009 Germany
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 163 lb 4/8/2009 Physician
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 163 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Other Serious 1/8/2009 Male 185 lb 4/14/2009 Germany
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Female 163 lb 4/27/2009 Physician
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2009 84 Female 163 lb 4/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 11/1/2008 60 Male 5/1/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2009 84 Female 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Prosthesis Implantation Other Serious 1/8/2009 Male 161 lb 5/28/2009 Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 8/20/2008 71 Female 6/10/2009 Physician Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4/2/2009 39 Female 110 lb 4/28/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/3/2009 Female 7/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Respiratory Rate Increased Disability 8/26/2009 78 Female 96 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Hypotension Disability 9/2/2009 79 Male 171 lb 9/3/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Rate Increased Life Threatening 8/12/2009 84 Female 186 lb 8/13/2009 United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Urticaria Other Serious 8/1/2008 Female 126 lb 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
No Adverse Event Death 9/3/2009 Male 12/2/2009 Pharmacist United States
Primary
Concomitant
Surgery Other Serious 2/1/2009 Male 12/7/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2009 Male 220 lb 1/20/2010 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/12/2008 72 Male 1/26/2010 Lawyer United States
Primary
Concomitant
Klebsiella Bacteraemia Hospitalization 1/1/2009 62 Female 2/18/2010 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/12/2008 72 Male 175 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 6/12/2008 72 Male 175 lb 3/25/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Sepsis Other Serious 10/1/2009 54 Female 172 lb 4/23/2010 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 4/15/2010 80 Male 194 lb 4/19/2010 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 79 Male 4/28/2010 Other Health Professional United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 2/27/2010 38 Female 168 lb 3/4/2010 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10/1/2009 63 Male 229 lb 5/10/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 79 Male 5/10/2010 Pharmacist United States
Primary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/7/2010 77 Male 214 lb 5/14/2010 Physician Canada
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 4/7/2010 77 Male 214 lb 4/21/2010 Physician Canada
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/7/2010 77 Male 214 lb 4/29/2010 Physician Canada
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/10/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 8/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 2/1/2008 39 Female 143 lb 9/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 6/17/2010 66 Male 284 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 10/1/2007 56 Male 223 lb 9/16/2010 Lawyer United States
Primary
Concomitant
No Reaction On Previous Exposure To Drug Hospitalization 8/23/2010 77 Male 9/13/2010 Austria
Primary
Concomitant
Urticaria Hospitalization 8/23/2010 77 Male 10/12/2010 Austria
Primary
Concomitant
Wound Dehiscence Other Serious 2/1/2008 39 Female 143 lb 12/1/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 77 Male 159 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 36 Female 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain 6/1/2010 59 Female 182 lb 11/6/2010 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain 12/1/2010 64 Female 2/2/2011 Consumer United States
Primary
Concomitant
Hypovolaemia Other Serious 2/29/2008 39 Female 143 lb 2/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 3/8/2007 39 185 lb 4/1/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 3/8/2007 39 185 lb 4/1/2011 Lawyer United States
Primary
Concomitant
Anxiety Hospitalization 12/16/2005 55 Male 236 lb 4/11/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious Female 5/10/2011 Consumer United States
Primary
Concomitant
Renal Disorder Death 5/9/2011 44 Male 5/13/2011 Other Health Professional United States
Primary
Concomitant
Neck Pain 4/9/2011 69 Female 5/25/2011 Consumer United States
Primary
Concomitant
Oral Fungal Infection Hospitalization 2/1/2011 75 Male 5/24/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/25/2010 57 Female 5/31/2011 Consumer United States
Primary
Concomitant
Respiratory Rate Decreased Other Serious 83 Male 165 lb 6/14/2011 Pharmacist Canada
Primary
Concomitant
Heart Rate Irregular Hospitalization 3/14/2011 84 Male 6/24/2011 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 3/14/2011 84 Male 6/27/2011 Physician United States
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2003 56 Female 155 lb 7/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Injury Disability Male 7/14/2011 Lawyer United States
Primary
Concomitant
Renal Haemorrhage Other Serious 3/1/2011 57 Female 7/15/2011 Consumer United States
Primary
Concomitant
Paronychia Other Serious Male 8/4/2011 Physician United States
Primary
Concomitant
Excessive Granulation Tissue Hospitalization 1/1/2003 56 Female 155 lb 8/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 237 lb 8/9/2011 Physician United States
Primary
Concomitant
Hyperkeratosis Death 11/1/2006 40 Female 8/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Dysplastic Naevus Other Serious 1/1/2003 56 Female 155 lb 8/11/2011 United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 72 Female 9/6/2011 Consumer Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/25/2010 57 Female 9/7/2011 Consumer United States
Primary
Concomitant
Arteriosclerosis Other Serious Male 9/22/2011 Lawyer United States
Primary
Concomitant
Dysuria Other Serious 54 Female 10/3/2011 Pharmacist Austria
Primary
Secondary
Concomitant
Blood Urine Present Other Serious Male 10/5/2011 Consumer United States
Primary
Concomitant
Tooth Fracture Other Serious 11/25/2010 57 Female 10/13/2011 Consumer United States
Primary
Concomitant
Dysphagia Other Serious 8/15/2011 78 Male 10/21/2011 Physician United States
Primary
Concomitant
Anti-erythrocyte Antibody Positive Other Serious 3/29/2011 60 Female 258 lb 8/18/2011 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 10/17/2011 68 Male 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Bronchitis 12/14/2010 60 Female 175 lb 10/28/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Death 6/1/2007 48 Male 227 lb 10/31/2011 Physician United States
Primary
Concomitant
Agitation Death 11/2/2011 48 Female 11/4/2011 Pharmacist United States
Primary
Concomitant
Fibula Fracture Hospitalization Male 11/15/2011 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/15/2011 68 Male 11/16/2011 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/24/2011 73 Male 11/23/2011 Physician Spain
Primary
Concomitant
Transitional Cell Cancer Of The Renal Pelvis And Ureter Hospitalization 1/1/2011 79 Male 11/23/2011 Physician United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious Male 11/25/2011 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/15/2011 68 Male 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 11/1/2011 74 Male 12/1/2011 Pharmacist Canada
Primary
Concomitant
Pneumonia Aspiration Other Serious 8/15/2011 78 Male 12/2/2011 Physician United States
Primary
Concomitant
Urethral Obstruction Disability Male 12/2/2011 Lawyer United States
Primary
Concomitant
Energy Increased Other Serious 11/28/2011 57 Male 12/9/2011 Other Health Professional United States
Primary
Concomitant
Transitional Cell Carcinoma Hospitalization 8/23/2010 61 Male 182 lb 12/22/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Other Serious 71 Male 12/22/2011 Pharmacist United States
Primary
Concomitant
Tooth Fracture Other Serious 11/25/2010 57 Female 12/27/2011 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Chest Pain Other Serious Male 1/2/2012 Lawyer United States
Primary
Concomitant
Post Procedural Complication Other Serious 9/1/2011 65 Male 1/3/2012 Physician United States
Primary
Concomitant
Underdose Hospitalization 12/7/2010 53 Male 287 lb 1/24/2012 Physician Germany
Primary
Concomitant
Nausea 1/24/2011 44 Male 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 12/1/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Rash Macular 8/31/2011 68 Male 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Reaction 12/15/2011 63 Female 1/29/2012 Consumer United States
Primary
Concomitant
Dysgeusia Hospitalization 7/8/2011 73 Male 190 lb 2/1/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myasthenia Gravis Hospitalization 12/19/2011 58 Female 192 lb 2/13/2012 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 3/27/2009 84 Female 154 lb 2/13/2012 Physician United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 10/15/2011 68 Male 2/21/2012 Physician United States
Primary
Secondary
Concomitant
Femoral Neck Fracture Hospitalization 3/27/2009 84 Female 154 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Patella Fracture Other Serious 9/18/2008 72 Female 166 lb 3/7/2012 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 62 Female 3/15/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Chest Pain Other Serious Male 3/19/2012 Physician United States
Primary
Concomitant
Delirium Other Serious 62 Female 3/20/2012 Physician Austria
Primary
Secondary
Concomitant
Delirium Hospitalization 9/1/2010 62 Female 3/22/2012 Physician Austria
Primary
Secondary
Concomitant
Sepsis Other Serious 62 Female 3/19/2012 Other Health Professional
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 10/15/2011 68 Male 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Renal Cancer Other Serious 1/1/2012 61 Male 3/28/2012 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 9/1/2010 62 Female 4/3/2012 Other Health Professional Austria
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/1/2010 47 Female 130 lb 4/13/2012 Lawyer United States
Primary
Concomitant
Tachycardia Other Serious Male 4/20/2012 Physician United States
Primary
Concomitant

Drug Data