Provigil combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dysgeusia 9/1/2005 Female 1/5/2006 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 8/4/2006 59 Female 11/30/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 8/4/2006 59 Female 4/5/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/18/2007 65 Female 189 lb 1/2/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/18/2007 65 Female 189 lb 1/22/2008 Consumer United States
Primary
Concomitant
No Adverse Event Other Serious 12/18/2007 65 Female 189 lb 1/22/2008 Consumer United States
Primary
Concomitant
Wheelchair User Other Serious 1/28/1992 4/9/2008 United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 86 Female 4/11/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 10/1/2007 75 Female 185 lb 5/13/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 2/25/2008 70 Female 152 lb 6/18/2008 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 7/25/2008 69 Male 8/27/2008 Physician United States
Primary
Concomitant
Prostate Cancer Stage Iii Other Serious 1/1/2008 63 Male 9/17/2008 United States
Primary
Concomitant
Rash Generalised 4/1/2008 71 Female 225 lb 6/3/2008 Consumer United States
Primary
Concomitant
Stress Other Serious 1/1/2008 63 Male 10/7/2008 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 Male 237 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Tinnitus 1/1/2003 54 Female 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment 8/1/2008 67 Male 11/14/2008 United States
Primary
Concomitant
Pancreatitis Hospitalization 9/17/2008 64 Male 12/1/2008 Physician United States
Primary
Concomitant
Urine Odour Abnormal 12/27/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Atrioventricular Block First Degree Other Serious 1/16/2009 Male 245 lb 2/2/2009 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 1/1/2008 63 Male 2/19/2009 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Hospitalization 2/17/2009 38 Male 2/27/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 58 Female 172 lb 3/19/2009 United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 4/9/2009 United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 4/10/2009 United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 5/18/2009 United States
Primary
Concomitant
Thalamic Infarction Hospitalization 3/1/2009 61 Male 5/27/2009 United States
Primary
Concomitant
Fatigue Hospitalization 62 Male 188 lb 5/22/2009 Pharmacist United States
Primary
Concomitant
Oesophageal Spasm Hospitalization 2/27/2009 Female 245 lb 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 7/16/2009 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 6/1/2009 Female 278 lb 7/27/2009 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2003 54 Female 294 lb 7/28/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 2/27/2009 Female 245 lb 8/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 8/7/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2009 52 Female 8/10/2009 United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 1/1/2009 Male 134 lb 8/17/2009 United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2009 Male 135 lb 8/27/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Prurigo Other Serious 7/1/2009 55 Female 9/4/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 2/27/2009 Female 245 lb 9/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 8/22/2009 Female 145 lb 9/11/2009 Other Health Professional United States
Primary
Concomitant
No Adverse Event 58 Female 172 lb 9/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Syncope Other Serious 8/22/2009 Female 145 lb 9/30/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 2/27/2009 Female 245 lb 10/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 2/17/2009 38 Male 10/2/2009 Other Health Professional United States
Primary
Concomitant
Prostate Cancer Other Serious 7/7/2008 63 Male 10/26/2009 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 3/1/2009 58 Female 10/19/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/4/2009 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 11/11/2009 48 Male 250 lb 11/12/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/5/2002 53 Female 294 lb 11/17/2009 United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 8/20/2009 Female 176 lb 11/17/2009 Consumer United States
Primary
Concomitant
Fatigue 8/9/2009 63 Male 11/18/2009 Consumer United States
Primary
Concomitant
Flushing 8/26/2009 Female 234 lb 11/25/2009 Consumer United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 1/1/2009 Male 134 lb 11/30/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/24/2009 Consumer United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 10/1/2009 42 Male 181 lb 12/2/2009 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 4/1/2009 66 Male 134 lb 12/14/2009 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2008 61 Male 224 lb 1/22/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 1/25/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2009 48 Female 1/15/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 2/11/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2009 52 Female 2/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased 1/1/2007 Female 3/25/2010 Consumer United States
Primary
Concomitant
Uterine Leiomyoma Hospitalization 12/1/2009 48 Female 134 lb 3/19/2010 United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/6/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/15/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Fatigue Other Serious 8/1/2009 60 Female 191 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Sepsis Other Serious 10/1/2009 54 Female 172 lb 4/23/2010 Pharmacist United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/26/2010 United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/28/2010 United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Coldness Other Serious 60 Female 225 lb 4/30/2010 Consumer United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 5/4/2010 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10/1/2009 63 Male 229 lb 5/10/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/10/2010 United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 8/20/2009 72 Female 176 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Wheelchair User Other Serious 1/28/1992 45 Female 160 lb 5/14/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Hospitalization 5/1/2009 52 Female 5/14/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/27/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/4/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/10/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/16/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/22/2010 United States
Primary
Concomitant
Drug Ineffective Male 276 lb 6/29/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 7/12/2010 United States
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 9/1/2009 7/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased 8/23/2008 57 Female 154 lb 7/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/11/2010 38 Female 123 lb 8/13/2010 Physician United States
Primary
Concomitant
Fibromyalgia Other Serious Female 274 lb 8/13/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/17/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/20/2010 Consumer United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/1/2009 48 Female 8/16/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 8/24/2010 United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 274 lb 8/18/2010 United States
Primary
Secondary
Vomiting Other Serious 7/1/1999 60 Female 8/25/2010 United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious 43 Female 8/27/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious Female 275 lb 8/24/2010 United States
Primary
Secondary
Fibromyalgia Other Serious Female 274 lb 8/24/2010 Consumer United States
Primary
Secondary
Flushing 4/14/2010 46 Male 8/28/2010 United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 273 lb 8/30/2010 Consumer United States
Primary
Concomitant
Fibromyalgia Other Serious 8/6/2010 43 Female 273 lb 8/31/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 9/1/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/1/2010 Consumer
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 8/30/2010 Consumer United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 274 lb 9/2/2010 Consumer United States
Primary
Secondary
Fibromyalgia Other Serious 8/1/2010 43 Female 274 lb 9/3/2010 Consumer United States
Primary
Secondary
Sensory Disturbance Hospitalization 12/15/2009 59 Male 9/6/2010 United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 274 lb 9/7/2010 Consumer United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious 1/1/2010 43 Female 274 lb 9/2/2010 United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/2/2010 United States
Primary
Secondary
Fibromyalgia Other Serious 43 Female 274 lb 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 6/1/2009 47 Female 9/9/2010 Physician United States
Primary
Concomitant
Fibromyalgia Other Serious 43 Female 9/10/2010 Consumer United States
Primary
Secondary
Tricuspid Valve Incompetence Other Serious Female 10/8/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 10/12/2010 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 38 Female 123 lb 10/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/22/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Vision Blurred Hospitalization 7/18/2010 49 Female 194 lb 11/8/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious Female 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Hair Texture Abnormal Other Serious 6/1/2010 58 Female 119 lb 12/8/2010 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious Female 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/29/2010 50 Female 302 lb 12/17/2010 Other Health Professional United States
Primary
Concomitant
Off Label Use Other Serious 58 Female 119 lb 12/23/2010 Consumer United States
Primary
Concomitant
Cold Sweat Other Serious 11/1/2009 51 Female 1/7/2011 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 1/1/2000 51 Male 237 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Hospitalization 12/15/2009 59 Male 1/13/2011 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 1/1/2000 51 Male 237 lb 1/21/2011 United States
Primary
Secondary
Concomitant
Lacrimation Increased Other Serious 1/29/2003 1/27/2011 United States
Primary
Concomitant
Rhinorrhoea 9/2/2010 66 Female 1/29/2011 Consumer United States
Primary
Concomitant
Epistaxis 11/23/2010 61 Female 1/30/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 1/29/2003 2/11/2011 United States
Primary
Concomitant
Sinus Headache Other Serious 12/10/2007 45 Female 209 lb 3/4/2011 Consumer United States
Primary
Concomitant
Sensory Disturbance Hospitalization 12/15/2009 59 Male 3/3/2011 United States
Primary
Concomitant
Hypothyroidism Hospitalization 1/29/2003 3/11/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 12/15/2009 59 Male 3/16/2011 Consumer United States
Primary
Concomitant
Decreased Interest Other Serious 6/1/2009 63 Female 134 lb 3/18/2011 Consumer United States
Primary
Concomitant
Fibromyalgia Other Serious Female 273 lb 3/22/2011 Consumer United States
Primary
Secondary

Drug Data