Prograf combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Death 3/15/2005 62 Male 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Radiation Oesophagitis Other Serious 12/23/2005 61 Male 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 10/28/2006 44 Female 12/21/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Radiation Oesophagitis Hospitalization 12/23/2005 61 Male 12/29/2006 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 57 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 43 Female 3/15/2007 Consumer Australia
Primary
Secondary
Concomitant
Monarthritis Hospitalization 4/1/2007 34 Male 152 lb 6/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/22/2007 30 Female 176 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Disability 6/5/2005 41 Male 9/20/2007 Physician Japan
Primary
Concomitant
Pharmaceutical Product Complaint 65 Male 10/24/2007 Consumer United States
Primary
Concomitant
Hypovolaemia Hospitalization 3/1/2007 70 Female 10/24/2007 United States
Primary
Secondary
Concomitant
Radiation Oesophagitis Hospitalization 12/23/2005 61 Male 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Acute Death 7/1/2007 75 Female 108 lb 11/5/2007 Physician Japan
Primary
Concomitant
Neck Pain Required Intervention 1/21/2008 Female 134 lb 2/2/2008 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/26/2007 75 Male 176 lb 10/2/2007 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 217 lb 4/30/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/30/2008 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 10/2/2008 59 Male 10/23/2008 Physician Germany
Primary
Concomitant
Liver Transplant Rejection Death 10/4/2008 54 Female 97 lb 11/11/2008 Consumer Brazil
Primary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 Female 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Liver Transplant Rejection Death 10/4/2008 54 Female 97 lb 12/8/2008 Other Health Professional Brazil
Primary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/9/2009 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/28/2009 Consumer Brazil
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/15/2008 63 Male 172 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 3/14/2006 Male 203 lb 2/6/2009 Physician United States
Primary
Concomitant
Cardiac Arrest Death 4/8/2009 45 Male 5/4/2009 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 7/5/2007 Female 176 lb 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious Male 5/19/2009 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 7/4/2007 61 Male 5/20/2009 Physician Germany
Primary
Concomitant
Pain Hospitalization 5/5/2009 28 Male 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 5/5/2009 28 Male 6/9/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2007 61 Male 154 lb 6/16/2009 Physician Germany
Primary
Concomitant
Wound Disability 2/15/2009 51 Male 225 lb 6/25/2009 Physician United States
Primary
Concomitant
Wound Disability 2/15/2009 51 Male 225 lb 7/6/2009 Physician United States
Primary
Concomitant
Sepsis Death 7/1/2007 75 Female 108 lb 7/24/2009 Physician Japan
Primary
Concomitant
Sepsis Death 7/1/2007 75 Female 108 lb 8/10/2009 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious Male 9/2/2009 Other Health Professional United States
Primary
Concomitant
Refractory Anaemia Other Serious 6/10/2008 Male 220 lb 9/23/2009 Physician United States
Primary
Concomitant
Sluggishness Life Threatening 6/1/2009 Male 169 lb 6/4/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 10/1/2008 31 Female 120 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 10/1/2008 31 Female 120 lb 10/22/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 30 Female 11/17/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 30 Female 11/24/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 11/6/2009 Female 12/10/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 30 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Skin Lesion 5/15/2008 Male 235 lb 12/11/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 30 Female 1/11/2010 United States
Primary
Concomitant
Swelling Hospitalization 8/24/2006 Male 1/29/2010 Physician United States
Primary
Concomitant
Renal Transplant Other Serious 3/6/2009 29 Female 79 lb 1/29/2010 Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 30 Female 1/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Female 2/18/2010 Lawyer United States
Primary
Concomitant
Urosepsis Other Serious 11/1/2009 Female 99 lb 3/15/2010 Physician Germany
Primary
Secondary
Concomitant
Protein Total Decreased Life Threatening 1/26/2010 65 Female 99 lb 3/16/2010 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 58 Female 110 lb 5/4/2010
Primary
Secondary
Renal Injury Other Serious 58 110 lb 5/4/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 53 Female 150 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 58 Female 110 lb 5/25/2010 Pharmacist Japan
Primary
Concomitant
Interacting
Swelling Hospitalization 8/24/2006 41 Male 6/2/2010 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/29/2009 45 Male 133 lb 4/13/2010 United States
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 6/11/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 11/29/2009 45 Male 133 lb 5/26/2010 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 11/29/2009 45 Male 133 lb 6/7/2010 Physician United States
Primary
Concomitant
Pulmonary Sepsis Other Serious 6/6/2005 56 Female 170 lb 7/9/2010 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/15/2010 71 Male 101 lb 8/13/2010 Physician Germany
Primary
Concomitant
Interacting
Diabetic Complication Death 55 Male 148 lb 8/6/2010 Physician United States
Primary
Concomitant
Atrioventricular Block Complete Other Serious 7/6/2010 70 Female 106 lb 8/19/2010 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 63 Female 8/20/2010 Physician United States
Primary
Concomitant
Stress Fracture Other Serious 52 Female 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 6/6/2005 56 Female 170 lb 9/14/2010 Physician Germany
Primary
Secondary
Concomitant
Foot Fracture Other Serious 3/23/2010 58 Female 209 lb 9/9/2010 Consumer United States
Primary
Concomitant
Death Death 9/5/2010 58 Male 157 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 34 Female 9/16/2010 United States
Primary
Concomitant
Foot Fracture Other Serious 3/23/2010 58 Female 209 lb 10/8/2010 Physician United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2003 58 Male 157 lb 10/12/2010 Physician United States
Primary
Concomitant
Sluggishness Hospitalization Female 115 lb 11/4/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 10/12/2010 66 Male 181 lb 10/27/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 12/6/2010 Consumer United States
Primary
Secondary
Concomitant
Right Ventricular Failure Disability 10/26/2010 65 Male 172 lb 11/19/2010 Physician Germany
Primary
Concomitant
Renal Abscess Hospitalization 11/1/2009 65 Female 99 lb 1/5/2011 Physician Germany
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 1/7/2011 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 9/1/2009 41 Female 149 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Fall Other Serious 1/1/2010 2/8/2011 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 58 Female 110 lb 2/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 12/23/2010 52 Female 2/18/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Death Male 3/1/2011 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 6/14/2010 3/7/2011 Other Health Professional United States
Primary
Concomitant
Aspergillosis Life Threatening 8/30/1997 3/11/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 3/18/2011 Physician United States
Primary
Concomitant
Nephrolithiasis Hospitalization 3/1/2009 53 Male 192 lb 3/23/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hyperglycaemia 3/18/2011 62 Male 192 lb 4/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2004 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2004 4/22/2011 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/11/2010 72 Female 181 lb 4/25/2011 Consumer United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 1/1/2011 51 Female 174 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/1/2010 49 Male 130 lb 5/6/2011 Physician United States
Primary
Concomitant
Heart Rate Decreased Other Serious 6/18/2010 73 Female 181 lb 5/19/2011 Consumer United States
Primary
Concomitant
Snoring Hospitalization 48 Male 230 lb 5/19/2011 Consumer United States
Primary
Concomitant
Vascular Stenosis Other Serious 1/1/2011 60 Female 240 lb 6/7/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 9/1/2009 41 Female 130 lb 6/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 4/15/2011 72 Female 6/20/2011 Physician Spain
Primary
Secondary
Concomitant
Vascular Stenosis Other Serious 1/1/2011 60 Female 240 lb 6/24/2011 Consumer United States
Primary
Concomitant
Skin Induration Death 1/1/2004 39 Female 117 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/1/2009 41 Female 130 lb 7/20/2011 Consumer United States
Primary
Secondary
Concomitant
Bile Duct Stone Other Serious 5/1/2005 7/19/2011 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 1/1/1997 47 Female 139 lb 7/20/2011 Physician United States
Primary
Concomitant
Cholecystitis Chronic Other Serious Female 127 lb 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 8/7/2011 64 Female 139 lb 8/10/2011 Pharmacist United States
Primary
Concomitant
Pain Hospitalization 1/1/2009 48 Female 8/12/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue Other Serious Male 9/6/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis C Death Female 9/16/2011 Other Health Professional United States
Primary
Concomitant
Vascular Graft Other Serious 1/1/2002 9/20/2011 Consumer United States
Primary
Concomitant
Decreased Appetite Other Serious 3/1/2011 9/21/2011 Consumer United States
Primary
Concomitant
Concomitant Disease Progression Hospitalization 8/24/2006 41 Male 9/25/2011 Physician United States
Primary
Concomitant
Induration Other Serious 3/1/2007 67 Female 230 lb 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased 12/23/2010 52 Female 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chronic Allograft Nephropathy Other Serious 10/1/2010 31 Male 185 lb 10/7/2011 Consumer United States
Primary
Concomitant
Confusional State Death 7/1/2011 43 Male 218 lb 10/10/2011 Pharmacist United States
Primary
Concomitant
Hydronephrosis Hospitalization 6/28/2011 64 Female 99 lb 10/13/2011 Consumer United States
Primary
Concomitant
Urethral Stenosis Hospitalization 7/1/2011 10/17/2011 Consumer United States
Primary
Concomitant
Paranoia Other Serious Male 10/19/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/17/2011 42 Male 191 lb 10/19/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 7/25/2011 10/19/2011 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 1/1/2011 10/24/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Death 6/1/2007 48 Male 227 lb 10/31/2011 Physician United States
Primary
Concomitant
Bronchitis Hospitalization 9/17/2011 42 Male 191 lb 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 9/17/2011 42 Male 191 lb 11/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Memory Impairment Death 7/1/2010 42 Male 218 lb 11/7/2011 Pharmacist United States
Primary
Concomitant
Death Death 9/7/2011 62 Male 185 lb 11/8/2011 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 10/1/2010 49 Male 130 lb 11/11/2011 Other Health Professional United States
Primary
Concomitant
Spinal Cord Compression Other Serious 1/1/2002 11/14/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2010 31 Male 185 lb 11/18/2011 Other Health Professional United States
Primary
Concomitant
Transplant Failure Other Serious 9/7/2011 62 Male 185 lb 11/21/2011 Physician United States
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 7/12/2011 11/23/2011 Consumer United States
Primary
Concomitant
Spinal Cord Compression Other Serious 1/1/2002 11/23/2011 Consumer United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization 1/1/2002 11/28/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 7/26/2011 61 Male 185 lb 12/2/2011 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2010 65 Male 174 lb 12/15/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious Male 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Influenza Hospitalization 1/1/2011 12/22/2011 Physician United States
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant
Death Death 5/2/2011 42 Male 1/16/2012 Other Health Professional United States
Primary
Concomitant

Drug Data