Avastin combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 2/16/2006 61 Female 139 lb 3/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 3/14/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2006 61 Female 139 lb 3/22/2006 Physician Australia
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/12/2006 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/17/2006 Physician Austria
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 5/23/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 5/26/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/19/2006 Male 6/1/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/12/2005 57 Female 6/5/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 5/2/2006 71 Female 185 lb 6/12/2006 Physician Spain
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 63 Male 6/16/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/5/2006 64 Male 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/5/2006 64 Male 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 8/14/2006 75 Female 170 lb 10/5/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Stridor Life Threatening 11/27/2006 67 Male 234 lb 1/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/29/2006 66 Male 173 lb 1/26/2007 Physician United Kingdom
Primary
Secondary
Leukocytoclastic Vasculitis Hospitalization 4/20/2006 Male 205 lb 4/11/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 3/22/2007 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 3/22/2007 Female 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/26/2007 53 Male 141 lb 9/14/2007 Consumer United Kingdom
Primary
Concomitant
Uveitis Other Serious 11/23/2007 Female 12/14/2007 Physician United Kingdom
Primary
Concomitant
Uveitis Other Serious 11/16/2007 Female 12/17/2007 Physician United Kingdom
Primary
Concomitant
Uveitis Other Serious 11/8/2007 Male 12/17/2007 Physician United Kingdom
Primary
Concomitant
Uveitis Other Serious 11/23/2007 Female 12/20/2007 Physician United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 4/30/2006 Male 205 lb 3/27/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Prinzmetal Angina Other Serious 12/9/2007 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Fibrinogen Increased Other Serious Male 8/1/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/1/2007 Female 7/30/2008 Physician United States
Primary
Concomitant
Anaphylactic Shock Hospitalization 6/19/2007 9/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Disorder Other Serious 28 Female 10/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Intraocular Pressure Increased Hospitalization 10/10/2008 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardiomyopathy Hospitalization 4/18/2008 67 Female 11/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/1/2008 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Diverticular Perforation Life Threatening 11/4/2008 Female 12/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Diverticular Perforation Life Threatening 11/4/2008 Female 12/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 11/6/2008 Male 12/30/2008 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 1/30/2009 Female 2/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/9/2008 85 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/9/2008 85 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 1/29/2009 Male 293 lb 3/8/2009 Pharmacist United States
Primary
Concomitant
Cerebral Ischaemia Life Threatening 11/21/2008 Female 4/7/2009 Other Health Professional Germany
Primary
Concomitant
Renal Injury Other Serious 3/21/2009 Female 168 lb 6/18/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/4/2009 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/15/2009 6/19/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/21/2009 Female 168 lb 6/29/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/4/2009 Female 7/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/15/2009 Male 7/13/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/4/2009 Female 159 lb 8/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious Female 190 lb 9/4/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Life Threatening 9/17/2009 Female 148 lb 9/21/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 8/27/2009 Male 166 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 8/21/2009 Female 135 lb 10/6/2009 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/24/2009 Female 190 lb 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious Male 184 lb 11/6/2009 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 11/27/2006 Male 234 lb 11/10/2009 Consumer France
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 11/27/2006 67 Male 11/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/29/2009 Male 11/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious Male 184 lb 12/4/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/4/2009 Female 159 lb 12/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/19/2009 Female 12/31/2009 Physician Switzerland
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/6/2010 Physician United States
Primary
Concomitant
Bone Density Decreased Other Serious 2/1/2010 59 Female 203 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/15/2010 Physician United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/26/2010 United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/28/2010 United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 5/4/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/10/2010 United States
Primary
Concomitant
Pyrexia Life Threatening 1/6/2010 69 Female 203 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/21/2010 62 Male 171 lb 5/19/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 5/27/2010 United States
Primary
Concomitant
Vomiting Hospitalization 5/19/2010 64 Male 203 lb 5/27/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/4/2010 United States
Primary
Concomitant
Vomiting Hospitalization 5/19/2010 64 Male 203 lb 6/10/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/10/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/16/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 6/22/2010 United States
Primary
Concomitant
Peritonitis Required Intervention 6/15/2010 75 Female 120 lb 6/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Brain Stem Infarction Hospitalization 5/19/2010 64 Male 203 lb 6/24/2010 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/1/2009 81 Female 6/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/21/2010 62 Male 171 lb 7/1/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 2/1/2009 81 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Function Test Abnormal 1/1/2009 77 Male 130 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/1/2007 75 Male 184 lb 7/31/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2003 8/24/2010 United States
Primary
Concomitant
Vision Blurred Hospitalization 7/29/2010 70 Female 10/18/2010 Consumer United States
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 11/26/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 7/29/2010 70 Female 12/1/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Hospitalization 12/8/2010 61 Female 182 lb 12/9/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/8/2010 61 Female 182 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 84 Male 176 lb 1/18/2011 Other Health Professional Canada
Primary
Concomitant
Product Quality Issue Other Serious 12/21/2010 80 Female 1/19/2011 Physician United States
Primary
Concomitant
Lacrimation Increased Other Serious 1/29/2003 1/27/2011 United States
Primary
Concomitant
Diarrhoea Hospitalization 12/10/2010 75 Male 187 lb 2/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 69 Female 2/4/2011 Consumer United States
Primary
Concomitant
Haematochezia Hospitalization 11/22/2010 72 Male 2/9/2011 Physician Austria
Primary
Secondary
Concomitant
Anxiety Other Serious 1/29/2003 2/11/2011 United States
Primary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 9/20/2010 73 Male 155 lb 2/21/2011 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 11/22/2010 72 Male 2/23/2011 Physician Austria
Primary
Secondary
Concomitant
Hypothyroidism Hospitalization 1/29/2003 3/11/2011 Other Health Professional United States
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 81 Female 95 lb 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 12/10/2010 Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Injury Hospitalization 9/1/2006 57 Male 214 lb 4/6/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 9/9/2010 81 Female 95 lb 4/6/2011 Physician Japan
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 12/21/2010 80 Female 4/11/2011 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 5/13/2010 68 Female 141 lb 4/13/2011 Consumer United States
Primary
Concomitant
Bladder Disorder Hospitalization 1/29/2003 5/26/2011 Physician United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 12/19/2003 53 Female 205 lb 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 3/7/2011 68 Male 5/31/2011 Consumer Germany
Primary
Secondary
Concomitant
Hypoxia Life Threatening 5/23/2011 61 Female 170 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Alopecia Other Serious 3/29/2011 63 Male 163 lb 6/9/2011 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 77 Female 243 lb 6/17/2011 Pharmacist United States
Primary
Concomitant
Autoimmune Thyroiditis Other Serious 11/1/2009 75 Male 181 lb 6/27/2011 Physician Israel
Primary
Concomitant
Cardiac Operation Hospitalization 2/7/2011 63 Male 6/30/2011 Physician Netherlands
Primary
Concomitant
Mastoid Disorder Other Serious 12/19/2003 53 Female 205 lb 7/7/2011 United States
Primary
Secondary
Concomitant
Night Sweats Other Serious 12/19/2003 53 Female 205 lb 7/17/2011 United States
Primary
Secondary
Concomitant
Amnesia Other Serious 1/29/2003 7/26/2011 Other Health Professional United States
Primary
Concomitant
Metabolic Disorder Other Serious 3/7/2011 68 Male 9/8/2011 Physician Germany
Primary
Secondary
Concomitant
Metabolic Disorder Other Serious 3/7/2011 68 Male 9/15/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Meningoencephalitis Bacterial Disability 3/31/2011 78 Male 156 lb 9/22/2011 Consumer United States
Primary
Concomitant
Metabolic Disorder Other Serious 3/7/2011 68 Male 9/23/2011 Consumer Germany
Primary
Secondary
Concomitant
Blood Creatine Increased Disability 3/7/2011 68 Male 9/26/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Cheilitis Disability 4/4/2008 75 Female 149 lb 10/5/2011 United Kingdom
Primary
Secondary
Concomitant
Eosinophilia 6/30/2011 78 Female 141 lb 10/16/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 6/29/2011 73 Male 132 lb 10/19/2011 Physician Germany
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 7/21/2010 72 Male 10/24/2011 United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/29/2003 49 Female 132 lb 10/21/2011 Lawyer United States
Primary
Concomitant
Pneumothorax Hospitalization 6/29/2011 73 Male 132 lb 10/31/2011 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/14/2009 66 Male 167 lb 11/2/2011 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 3/31/2011 78 Male 156 lb 11/10/2011 Physician United States
Primary
Concomitant
Myocardial Infarction Death 11/1/2010 73 Female 121 lb 11/15/2011 Physician Israel
Primary
Secondary
Concomitant
Bladder Disorder Hospitalization 1/29/2003 49 Female 132 lb 11/16/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 7/3/2011 77 Male 119 lb 11/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Incoherent Hospitalization 7/3/2011 77 Male 119 lb 11/21/2011 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Toxic Life Threatening 4/10/2011 75 Female 136 lb 11/22/2011 Spain
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/24/2011 United States
Primary
Secondary
Concomitant
Hepatitis Toxic Life Threatening 4/10/2011 75 Female 136 lb 11/29/2011 Spain
Primary
Secondary
Concomitant
Confusional State Hospitalization 7/3/2011 77 Male 119 lb 11/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Amnesia Hospitalization 7/3/2011 77 Male 119 lb 12/1/2011 United Kingdom
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Hepatitis Toxic Life Threatening 4/10/2011 75 Female 136 lb 12/7/2011 Physician Spain
Primary
Secondary
Concomitant
Cardiac Arrest Death 11/11/2011 72 Male 225 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Pain Disability 3/31/2011 78 Male 156 lb 12/16/2011 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/30/2011 57 Male 179 lb 12/21/2011 Physician Spain
Primary
Secondary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Disability 3/31/2011 78 Male 156 lb 12/28/2011 United States
Primary
Concomitant
Hypokalaemia Other Serious 10/1/2011 57 Female 92 lb 12/28/2011 United States
Primary
Secondary
Concomitant

Drug Data