Colchicine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 55 Male 220 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/2/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Myalgia Other Serious 3/7/2006 70 Male 252 lb 3/8/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 2/7/2006 65 Male 157 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2003 63 Female 168 lb 5/11/2006 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/23/2006 57 Male 192 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Overdose Death 9/26/2006 52 Male 190 lb 10/23/2006 United States
Primary
Concomitant
Nausea Hospitalization 7/7/2006 84 Male 134 lb 10/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 3/9/2007 89 Male 156 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Visual Field Defect Required Intervention 12/12/2006 86 Male 151 lb 1/12/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 66 Male 5/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 66 Male 6/1/2007 Other Health Professional United States
Primary
Secondary
Rib Fracture Hospitalization 1/1/2005 64 Male 200 lb 7/13/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Male 220 lb 7/23/2007 Physician United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 6/2/2007 64 Male 200 lb 9/20/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 66 Male 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis In Device Life Threatening 10/19/2007 62 Male 12/6/2007 Other Health Professional Switzerland
Primary
Concomitant
Localised Infection 9/24/2007 Female 132 lb 12/14/2007 Consumer United States
Primary
Concomitant
Myopathy Toxic Death 66 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/14/2007 85 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Myopathy Toxic Other Serious 66 Male 12/31/2007 United States
Primary
Secondary
Rhabdomyolysis Hospitalization 66 Male 1/7/2008 United States
Primary
Secondary
Concomitant
Liver Injury 6/6/2006 80 Male 8/20/2007 Physician United States
Primary
Concomitant
Thrombocytopenia 1/16/2008 65 Male 238 lb 1/23/2008 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 61 Female 2/8/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 66 Male 2/19/2008 United States
Primary
Concomitant
Rhabdomyolysis Death 66 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia 1/16/2008 65 Male 238 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
Neuromyopathy Other Serious 73 Male 6/16/2008 Netherlands
Primary
Interacting
Weight Increased 80 Female 150 lb 6/26/2008 Consumer United States
Primary
Concomitant
Swelling Face 80 Female 150 lb 6/26/2008 Consumer United States
Primary
Concomitant
Neuromyopathy Hospitalization 73 Male 6/26/2008 Netherlands
Primary
Concomitant
Interacting
Weight Decreased Other Serious 66 Male 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/11/2008 77 Male 160 lb 8/8/2008 United States
Primary
Secondary
Blood Glucose Increased Other Serious 9/9/2008 Male 234 lb 9/19/2008 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 73 Male 10/22/2008
Primary
Secondary
Blood Glucose Increased Other Serious 9/9/2008 Male 234 lb 11/3/2008 Consumer United States
Primary
Concomitant
Fluid Retention Other Serious 7/1/2008 80 Male 190 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Urine Odour Abnormal 12/27/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/6/2008 54 Female 12/11/2008 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2007 50 Male 12/19/2008 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 1/16/2008 65 Male 238 lb 12/23/2008 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 50 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 1/23/2009 Other Health Professional United States
Primary
Secondary
Poisoning Deliberate Death 50 Male 1/19/2009 Physician United States
Primary
Secondary
Psoriasis Hospitalization Male 380 lb 2/20/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 2/24/2009 58 Male 2/25/2009 Pharmacist United States
Primary
Secondary
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2008 82 Female 3/13/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/10/2008 82 Female 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/10/2008 82 Female 3/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vasodilatation Hospitalization 5/26/2006 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Disability 1/21/1909 Female 260 lb 3/18/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/17/2008 82 Female 3/19/2009
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 3/31/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2002 47 Male 195 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Retinal Haemorrhage Other Serious 1/1/1997 Female 4/8/2009 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/30/2009 77 Male 260 lb 5/1/2009 Pharmacist United States
Primary
Secondary
Syncope Other Serious 8/22/2002 85 Male 189 lb 4/27/2009 Physician United States
Primary
Concomitant
Hernia Hospitalization 69 Male 146 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Myalgia Other Serious 5/8/2009 Female 128 lb 5/8/2009 Physician United States
Primary
Concomitant
Vasodilation Procedure Hospitalization 5/26/2006 51 5/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2008 Female 6/1/2009 Consumer
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 6/4/2009 Consumer
Primary
Concomitant
Drug Ineffective 2/1/2009 Male 130 lb 6/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Wound Life Threatening 12/23/2008 65 Male 170 lb 6/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Recurrent Cancer Hospitalization 2/1/2009 Male 200 lb 6/24/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 78 Female 6/25/2009 Physician United States
Primary
Concomitant
Hypotension 9/16/2008 Male 6/30/2009 United States
Primary
Concomitant
Vertigo 11/15/2008 Male 6/30/2009 United States
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 7/1/2009 Physician United States
Primary
Concomitant
Product Quality Issue 1/27/2009 74 Male 6/25/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/4/2009 Consumer
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/14/2009 Consumer
Primary
Concomitant
Skin Discolouration Other Serious 5/26/2009 51 Female 441 lb 8/15/2009 United States
Primary
Concomitant
Wound Infection Other Serious 3/1/2008 68 Female 205 lb 8/20/2009 Lawyer United States
Primary
Concomitant
Pruritus 2/1/2006 Female 220 lb 8/21/2009 United States
Primary
Concomitant
Surgery Hospitalization 64 Male 8/20/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 9/1/2009 Physician
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 9/2/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 9/8/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/28/2007 61 Male 9/18/2009 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 2/23/2001 59 Male 190 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus 3/1/2004 54 Male 224 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 181 lb 9/24/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 8/1/2009 51 Male 9/30/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2000 50 Male 239 lb 10/14/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 10/17/2009 United States
Primary
Concomitant
Atrial Fibrillation Other Serious 10/18/2009 Female 10/28/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 10/14/2009 68 Female 11/2/2009 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 64 Male 201 lb 10/26/2009 United States
Primary
Concomitant
Vomiting 8/17/2009 62 11/9/2009 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 10/14/2009 68 Female 11/12/2009 Consumer United States
Primary
Secondary
Concomitant
Phlebitis Other Serious 8/6/2009 Male 250 lb 11/25/2009 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 64 Male 201 lb 11/18/2009 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 2/16/1996 Female 11/30/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/28/2005 70 Female 11/18/2009 United States
Primary
Concomitant
Phlebitis Other Serious 8/6/2009 Male 250 lb 12/2/2009 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 12/1/2009 Physician United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 78 Female 12/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2009 Male 250 lb 12/11/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Male 265 lb 12/16/2009 Physician United States
Primary
Concomitant
Osteoarthritis Hospitalization 12/5/2009 Male 190 lb 12/15/2009 United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 7/23/2009 55 Male 12/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Phlebitis Other Serious 8/6/2009 Male 250 lb 12/18/2009 Physician United States
Primary
Concomitant
Intestinal Perforation Hospitalization 11/23/2009 71 Male 12/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 10/14/2009 68 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 10/14/2009 68 Female 1/5/2010 Consumer United States
Primary
Secondary
Concomitant
Faeces Discoloured Other Serious 12/23/2009 51 Female 209 lb 1/5/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 66 Male 1/6/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 66 Male 1/6/2010 United States
Primary
Secondary
Concomitant
Interacting
Drug Interaction Hospitalization 8/26/2009 75 Male 157 lb 1/6/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 6/14/2009 Male 1/7/2010 Physician United States
Primary
Concomitant
Phlebitis Other Serious 8/6/2009 Male 250 lb 1/8/2010 Physician United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 78 Female 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 10/18/2009 69 Female 1/19/2010 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 10/14/2009 Female 1/21/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 46 Female 1/12/2010 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10/14/2009 Female 1/25/2010 Consumer United States
Primary
Concomitant
Phlebitis Other Serious 8/6/2009 Male 250 lb 1/26/2010 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization 8/26/2009 75 Male 157 lb 2/4/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Weight Increased 1/1/1994 50 Male 2/5/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Female 2/18/2010 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2008 Male 230 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 7/27/2006 3/24/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death Male 3/24/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization Male 320 lb 3/26/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death Male 139 lb 3/30/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2008 Male 230 lb 3/31/2010 Physician
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 3/25/2010 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2008 53 Male 230 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2008 52 Male 229 lb 4/6/2010 Physician United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization Male 320 lb 4/7/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2009 53 Male 4/7/2010 Physician Denmark
Primary
Secondary
Concomitant
Nausea Hospitalization 4/3/2010 76 Female 206 lb 4/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/8/2010 75 Female 4/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 4/22/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 4/8/2008 68 Male 5/14/2010 Lawyer United States
Primary
Concomitant
Wound Infection Other Serious 2/1/2008 68 Female 205 lb 5/14/2010 Lawyer United States
Primary
Concomitant

Drug Data