Primidone combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence 5/23/2005 79 Female 166 lb 1/5/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 7/1/2004 80 Male 190 lb 12/21/2005 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 4/14/2006 76 Male 218 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/22/2005 74 Male 8/1/2006 Consumer United States
Primary
Concomitant
Tension 4/15/2006 84 Male 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 7/15/2007 65 Female 8/6/2007 Pharmacist United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 11/4/2007 61 Male 11/19/2007 Consumer United States
Primary
Secondary
Staphylococcal Infection Hospitalization 11/4/2007 61 Male 1/4/2008 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 Female 148 lb 1/28/2008 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 2/27/2008 Female 190 lb 3/11/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/14/2008 Male 241 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Rash Generalised Life Threatening 4/1/2008 8/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Life Threatening 4/1/2008 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 4/1/2008 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 4/1/2008 66 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 66 Female 9/30/2008
Primary
Concomitant
Vomiting Other Serious 4/1/2007 Male 235 lb 10/15/2008 Consumer United States
Primary
Concomitant
Loss Of Consciousness Required Intervention 7/16/2008 55 Male 218 lb 7/31/2008 Pharmacist United States
Primary
Concomitant
Rash Generalised Other Serious 5/1/2008 66 Female 11/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 9/17/2008 64 Male 12/1/2008 Physician United States
Primary
Concomitant
Syncope Life Threatening 7/2/2008 63 Female 1/26/2009 Pharmacist United States
Primary
Concomitant
Pruritus 5/13/2008 73 Female 2/24/2009 Consumer United States
Primary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Rash Life Threatening 4/1/2009 Female 4/21/2009 Consumer United States
Primary
Concomitant
Suicidal Ideation Life Threatening 7/9/2008 45 Female 271 lb 4/22/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/1/2007 75 Male 5/14/2009 Consumer United States
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 11/7/2008 Male 129 lb 8/6/2009 Physician Belgium
Primary
Concomitant
Rash Generalised Other Serious 5/1/2008 66 Female 8/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 4/1/2008 66 Female 8/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/1/2009 73 Male 9/21/2009 Physician United States
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 11/7/2008 Male 129 lb 10/23/2009 Physician Belgium
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 4/1/2008 66 Female 10/23/2009 United Kingdom
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 11/12/2009 Physician Belgium
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 12/3/2009 Physician Belgium
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/7/2008 Male 129 lb 12/10/2009 Physician Belgium
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 12/16/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2008 78 Male 137 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 12/3/2009 62 Male 160 lb 12/24/2009 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/1/2009 72 Female 148 lb 1/20/2010 United States
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 2/3/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death Female 119 lb 2/2/2010 Physician United States
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Other Serious 3/26/2009 86 Female 110 lb 2/18/2010 Consumer Brazil
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Other Serious 86 Female 110 lb 2/22/2010 Consumer Brazil
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 3/26/2009 86 Female 110 lb 2/23/2010 Consumer Brazil
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 3/18/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2008 78 Male 137 lb 4/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/3/2009 72 Female 159 lb 4/19/2010 Physician United States
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 66 Male 266 lb 4/26/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Life Threatening 11/19/2009 66 Male 266 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Other Serious 3/26/2009 86 Female 110 lb 5/5/2010 Consumer Brazil
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Other Serious 86 Female 110 lb 5/5/2010 Consumer Brazil
Primary
Concomitant
Death Death 4/29/2010 79 Male 6/9/2010 Consumer United States
Primary
Concomitant
Pain In Extremity 10/26/2007 54 Female 180 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Death 4/29/2010 79 Male 7/20/2010 Other Health Professional United States
Primary
Concomitant
Diarrhoea 1/1/2009 52 Female 135 lb 8/4/2010 Consumer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 8/20/2010 United States
Primary
Secondary
Concomitant
Flushing 8/14/2009 57 Male 200 lb 8/27/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/22/2010 67 Male 238 lb 10/21/2010 Consumer United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 52 Female 11/9/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 11/29/2010 United States
Primary
Secondary
Concomitant
Nasal Discomfort 1/1/2000 63 Female 240 lb 11/9/2010 United States
Primary
Concomitant
Pain In Extremity 11/1/2010 80 Male 12/16/2010 Consumer
Primary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/21/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/25/1998 52 Female 12/30/2010 United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 9/19/2010 82 Male 145 lb 1/21/2011 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/17/2010 73 Male 230 lb 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/21/2011 Female 1/31/2011 Pharmacist United States
Primary
Concomitant
Stress Hospitalization 1/1/2010 58 Female 180 lb 2/16/2011 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 9/22/2010 67 Male 238 lb 2/16/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 9/19/2010 82 Male 145 lb 2/22/2011 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 9/22/2010 67 Male 238 lb 2/23/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/6/2011 47 Male 198 lb 2/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Otitis Media Chronic Hospitalization 1/25/1998 52 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/25/1998 52 Female 3/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization Female 4/7/2011 Consumer New Zealand
Primary
Concomitant
Leukocytosis Hospitalization 3/20/2011 4/20/2011 Physician United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2011 59 Male 6/7/2011 Consumer United States
Primary
Concomitant
Nausea 4/12/2011 70 Male 6/17/2011 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 5/1/2011 74 Male 210 lb 6/14/2011 Pharmacist United States
Primary
Concomitant
Ill-defined Disorder 11/1/2010 57 Female 6/17/2011 Consumer United States
Primary
Concomitant
Hepatic Congestion Death 3/20/2011 6/27/2011 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 5/1/2011 74 Male 463 lb 6/17/2011 Physician United States
Primary
Concomitant
Depression Hospitalization 1/1/2011 73 Female 236 lb 6/27/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Arthropathy Hospitalization 1/1/2011 59 Male 7/8/2011 Other Health Professional United States
Primary
Concomitant
Haematoma Other Serious 6/1/2011 68 Female 7/25/2011 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 69 Male 7/25/2011 Physician United States
Primary
Concomitant
Inflammation Other Serious Male 8/10/2011 Consumer United States
Primary
Concomitant
Dyspnoea Death 1/1/2011 73 Female 236 lb 8/9/2011 Other Health Professional Germany
Primary
Concomitant
Ear Infection Other Serious 5/1/2011 74 Male 210 lb 8/16/2011 Physician United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2011 59 Male 9/2/2011 Other Health Professional United States
Primary
Concomitant
Ear Infection Other Serious 5/1/2011 74 Male 210 lb 8/18/2011 Physician United States
Primary
Concomitant
Contusion 1/1/2011 59 Female 9/6/2011 Consumer United States
Primary
Concomitant
Abdominal Wound Dehiscence Hospitalization 10/7/2011 66 Male 159 lb 10/20/2011 Physician United States
Primary
Concomitant
Balance Disorder Hospitalization 6/1/2011 67 Male 11/10/2011 Physician United States
Primary
Concomitant
Oral Cavity Fistula Hospitalization 1/25/1998 52 Female 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Vision Blurred 11/16/2011 66 Male 160 lb 11/18/2011 Consumer United States
Primary
Concomitant
Arteriovenous Fistula Site Complication Disability 1/25/1998 52 Female 11/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myeloma Recurrence Disability 1/25/1998 52 Female 12/2/2011 Consumer United States
Primary
Secondary
Concomitant
Infusion Site Pruritus Other Serious 5/1/2011 74 Male 214 lb 12/20/2011 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 10/1/2011 47 Male 270 lb 12/28/2011 Consumer United States
Primary
Concomitant
Decubitus Ulcer Other Serious 6/1/2011 67 Male 1/6/2012 Physician United States
Primary
Concomitant
Back Pain Other Serious 5/25/2010 78 Male 183 lb 1/6/2012 Lawyer United States
Primary
Concomitant
Therapeutic Product Ineffective Required Intervention 8/30/2010 80 Male 260 lb 2/9/2012 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 12/1/2011 76 Male 146 lb 2/17/2012 Consumer United States
Primary
Concomitant
Constipation Other Serious 2/6/2012 77 Male 2/28/2012 Physician United States
Primary
Concomitant
Flank Pain 7/25/2011 74 Female 160 lb 12/20/2011 Consumer United States
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 1/1/2010 68 Female 3/6/2012 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/25/1998 52 Female 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Cataract Disability 1/25/1998 52 Female 3/26/2012 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 1/25/1998 52 Female 4/3/2012 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/24/2012 71 Female 165 lb 4/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/24/2012 71 Female 4/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/24/2012 71 Female 165 lb 4/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Meningioma Other Serious 1/1/2010 68 Female 4/20/2012 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/24/2012 76 Male 154 lb 4/26/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2012 76 Male 154 lb 5/7/2012 Other Health Professional United States
Primary
Concomitant
Benign Prostatic Hyperplasia Hospitalization 2/6/2012 77 Male 5/17/2012 Consumer United States
Primary
Concomitant
Amnesia 1/1/2011 74 Male 210 lb 6/4/2012 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 8/18/2011 56 Male 134 lb 6/19/2012 Physician United States
Primary
Concomitant
Blood Pressure Increased Male 6/21/2012 Consumer United States
Primary
Concomitant
Somnolence 1/1/2011 74 Male 210 lb 6/24/2012 Consumer United States
Primary
Concomitant
Rash Female 200 lb 7/3/2012 Consumer United States
Primary
Secondary
Concomitant
Kyphosis Other Serious 1/25/1998 52 Female 7/24/2012 Lawyer United States
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome Other Serious 6/14/2012 65 Male 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Tremor 74 Male 8/2/2012 Consumer United States
Primary
Concomitant
Ecchymosis Hospitalization 1/25/1998 52 Female 8/3/2012 Consumer United States
Primary
Secondary
Concomitant
Product Solubility Abnormal 1/1/2010 8/5/2012 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 6/19/2012 83 Female 159 lb 8/14/2012 Pharmacist Canada
Primary
Concomitant
Interacting
Insomnia Other Serious 6/1/2009 7/31/2012 Consumer United States
Primary
Concomitant
Tremor Other Serious Female 145 lb 10/12/2012 Lawyer Us
Primary
Concomitant
Tremor 2011 75 Male 210 lb 1/31/2013 Consumer Us
Primary
Concomitant
Rash Other Serious Female 200 lb 2/4/2013 Consumer Us
Primary
Secondary
Concomitant
Tremor 74 Male 9/27/2012 Consumer Us
Primary
Secondary
Concomitant
Underdose 2010 12/27/2012 Physician Country Not Specified
Primary
Concomitant
Faeces Discoloured 8/2012 87 Male 152 lb 9/6/2012 Consumer Us
Primary
Concomitant
Back Pain 8/2012 82 Female 9/27/2012 Consumer Us
Primary
Concomitant
Therapeutic Response Delayed 9/24/2012 76 Male 10/19/2012 Consumer Us
Primary
Concomitant
Convulsion Other Serious 10/1/2011 54 Male 10/24/2012 Physician Us
Primary
Concomitant
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Death Death 10/22/2012 68 Male 1/28/2013 Physician Us
Primary
Concomitant
Wound Other Serious Female 265 lb 6/21/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 265 lb 4/5/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Incorrect Dose Administered Other Serious 1/23/2013 92 Male 2/14/2013 Pharmacist Us
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/26/2013 82 Female 6/17/2013 Physician Us
Primary
Concomitant
Tremor Other Serious Female 212 lb 9/17/2012 Lawyer Us
Primary
Concomitant
X-ray Abnormal Disability 1/25/1998 52 Female 3/7/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data