Simvastatin combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastrointestinal Haemorrhage Other Serious 11/23/2004 66 Female 135 lb 12/21/2005 Consumer United States
Primary
Concomitant
Oesophageal Haemorrhage Other Serious 11/1/2004 78 Male 160 lb 12/27/2005 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2004 Female 157 lb 3/17/2006 Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Renal Failure Other Serious 1/13/2004 Female 157 lb 5/12/2006 Canada
Primary
Secondary
Concomitant
Pneumonitis 2/24/2006 79 Male 163 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2006 70 Male 6/19/2006 Physician Spain
Primary
Secondary
Concomitant
Pneumothorax 1/1/2005 Male 195 lb 8/8/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2004 Female 157 lb 11/1/2006 Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2005 84 Female 132 lb 11/3/2006 Consumer Brazil
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 8/3/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/15/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/25/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 72 Male 250 lb 1/8/2007 Consumer United States
Primary
Concomitant
Neurological Symptom Other Serious 72 Male 250 lb 1/9/2007 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 1/31/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/15/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/3/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 7/24/2006 64 Male 2/22/2007 Physician Belgium
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 42 Male 11/13/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/20/2006 65 Male 143 lb 4/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 11/1/2006 61 Female 198 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/1/2000 70 Male 148 lb 12/13/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 83 Male 178 lb 12/13/2006 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 12/1/2006 68 Female 170 lb 2/28/2007 United States
Primary
Concomitant
Middle Insomnia 1/1/2006 75 Female 170 lb 4/12/2007 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/18/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 6/22/2007 Consumer United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 7/1/2007 69 Male 132 lb 7/12/2007 Physician Spain
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 7/27/2007 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/2/2007 61 Male 198 lb 7/30/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 6/26/2007 87 Female 110 lb 8/7/2007 Consumer
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 8/9/2007 Physician Spain
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 7/30/2007 Female 157 lb 8/31/2007 United Kingdom
Primary
Concomitant
Syncope Hospitalization 8/13/2007 69 Male 303 lb 9/5/2007 Physician United States
Primary
Concomitant
Stent Placement Hospitalization 79 Male 9/26/2007 Consumer United States
Primary
Concomitant
Gastric Haemorrhage Other Serious Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Decreased 61 Female 198 lb 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 8/13/2007 Male 303 lb 10/9/2007 Physician United States
Primary
Concomitant
Prostate Cancer Hospitalization 79 Male 10/19/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 10/30/2007 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 11/2/2007 Physician Spain
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 11/29/2001 46 Male 262 lb 11/8/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased 8/1/2007 Male 11/8/2007 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 9/7/2007 66 Male 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 9/7/2007 66 Male 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Nightmare Other Serious 3/11/2007 Female 118 lb 11/19/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 11/13/2007 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2005 Male 11/22/2007 Consumer United States
Primary
Concomitant
Nausea Hospitalization 8/1/2007 Male 220 lb 12/11/2007 Physician United States
Primary
Concomitant
Pain In Extremity 85 Female 119 lb 12/21/2007 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 11/29/2001 46 Male 262 lb 1/10/2008 Consumer United States
Primary
Concomitant
Multiple Myeloma Other Serious 6/1/2007 Female 157 lb 1/29/2008 United Kingdom
Primary
Concomitant
Walking Disability Other Serious 11/1/2007 83 Male 1/30/2008 United States
Primary
Concomitant
Haemorrhage Urinary Tract Other Serious 5/1/2007 Male 150 lb 1/31/2008 Physician United States
Primary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 9/1/2007 Male 114 lb 12/5/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2006 68 Female 170 lb 3/14/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 6/26/2007 87 Female 110 lb 3/15/2008 Consumer
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 3/17/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/1/2007 Male 174 lb 3/10/2008 Physician United Kingdom
Primary
Concomitant
Pelvic Fracture Other Serious 3/1/2008 80 Female 3/19/2008 Consumer Canada
Primary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 4/18/2008 Consumer United Kingdom
Primary
Concomitant
Pericardial Effusion Hospitalization 4/7/2008 Male 4/28/2008 Physician Germany
Primary
Concomitant
Drug Ineffective 2/1/2008 80 Male 218 lb 4/30/2008 United States
Primary
Concomitant
Pericardial Effusion Hospitalization 4/7/2008 Male 115 lb 5/23/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 Female 161 lb 5/27/2008
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2008 80 Female 92 lb 5/19/2008 Physician Canada
Primary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 6/2/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 7/24/2006 Male 6/2/2008 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 161 lb 6/5/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 6/5/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 Female 172 lb 6/10/2008
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 6/11/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2006 Female 130 lb 6/13/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 Male 326 lb 6/17/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 172 lb 6/26/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 7/7/2008 United States
Primary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 7/14/2008 United States
Primary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 7/21/2008 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2007 54 Male 300 lb 7/28/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 7/29/2008 United States
Primary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 8/7/2008 United States
Primary
Concomitant
Skin Warm 6/25/2008 Female 8/19/2008 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 54 Male 300 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 Male 285 lb 8/26/2008 Other Health Professional United States
Primary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/1/2008 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 8/11/2008 74 Female 145 lb 9/22/2008 Other Health Professional United States
Primary
Concomitant
Swelling Hospitalization 1/1/2008 Male 9/29/2008 Physician United States
Primary
Concomitant
Skin Warm 6/25/2008 Female 9/29/2008 Consumer
Primary
Concomitant
Vertigo 76 Female 179 lb 10/7/2008 United States
Primary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 10/13/2008 United States
Primary
Concomitant
Skin Warm 6/25/2008 Female 10/16/2008 Physician
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 54 Male 300 lb 10/22/2008 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2008 Male 10/28/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 Male 237 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 11/11/2008 Pharmacist United States
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 10/5/2008 Female 12/12/2008 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 12/30/2008 Physician United States
Primary
Concomitant
Lung Neoplasm Other Serious 5/20/2008 Male 182 lb 1/9/2009 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Male 200 lb 1/21/2009 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 6/1/2008 Female 167 lb 1/22/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 1/30/2009 Physician United States
Primary
Concomitant
Skin Burning Sensation Other Serious 66 Male 2/17/2009 Pharmacist United States
Primary
Concomitant
Skin Necrosis Other Serious 66 Male 2/18/2009 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/7/2008 Male 200 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paranoia Other Serious 1/12/2009 Female 309 lb 2/26/2009 Consumer United Kingdom
Primary
Concomitant
Muscle Twitching Other Serious 2/18/2009 77 Female 133 lb 3/4/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/1/2008 Female 2/25/2009 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 3/19/2009 Consumer United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2009 Male 187 lb 3/19/2009 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 3/25/2009 Consumer United Kingdom
Primary
Concomitant
Cholecystectomy Hospitalization 11/1/2008 Male 155 lb 3/26/2009 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/7/2009 Male 200 lb 3/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Other Serious 3/25/2009 Male 4/2/2009 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 2/1/2009 Female 200 lb 4/1/2009 Consumer United States
Primary
Secondary
Concomitant
Tongue Haemorrhage Other Serious 10/20/2007 69 Female 4/3/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 4/3/2009 United States
Primary
Concomitant
Haematochezia Other Serious 3/1/2009 78 Male 4/8/2009 Consumer United States
Primary
Concomitant
Tongue Haemorrhage Hospitalization 10/20/2007 Female 4/16/2009 Consumer Germany
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious 1/1/1950 22 Male 150 lb 4/22/2009 Consumer United States
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/1/2008 Female 187 lb 4/28/2009 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization Female 105 lb 4/30/2009 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 3/1/2009 78 Male 174 lb 5/7/2009 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 5/3/2009 Female 150 lb 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Flatulence Other Serious 10/1/2008 Male 192 lb 5/14/2009 Physician United States
Primary
Concomitant
Muscle Twitching Other Serious 2/18/2009 77 Female 133 lb 5/15/2009 Consumer United States
Primary
Concomitant
Sepsis Death 75 Male 5/19/2009 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2003 Female 5/21/2009 United States
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 3/1/2009 Female 210 lb 5/26/2009 Consumer United Kingdom
Primary
Concomitant
Myalgia 3/16/2009 Female 5/27/2009 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 11/1/2007 Male 270 lb 5/26/2009 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 5/3/2009 Female 150 lb 5/28/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/7/2009 Male 200 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Irritation 3/17/2009 Male 148 lb 6/12/2009 Consumer United States
Primary
Concomitant
Haemoglobin Decreased 5/13/2009 6/12/2009 Physician United States
Primary
Concomitant
Ischaemic Cardiomyopathy Life Threatening 11/1/2007 Male 270 lb 6/11/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection 2/26/2009 Female 6/30/2009 United States
Primary
Concomitant

Drug Data