Nicotine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 9/24/2005 63 Male 179 lb 2/3/2006 Physician Australia
Primary
Secondary
Concomitant
Scrotal Haematoma Hospitalization 11/28/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/1/2005 82 Male 190 lb 11/2/2005 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Life Threatening 82 Female 4/13/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 1/9/2004 71 Female 168 lb 4/27/2006 Consumer Canada
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 1/25/2006 59 Male 250 lb 1/30/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/20/2006 65 Male 5/8/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 3/24/2006 53 Male 5/26/2006 United Kingdom
Primary
Concomitant
Nausea 6/7/2006 58 Male 160 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 5/11/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Haemorrhoids Hospitalization 6/26/2006 51 Male 220 lb 7/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 8/3/2006 59 Male 167 lb 8/17/2006 Consumer United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/28/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 1/24/2006 Male 176 lb 10/5/2006 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2006 47 Male 185 lb 10/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nicotine Dependence Life Threatening Female 10/31/2006 Consumer United Kingdom
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Presyncope Hospitalization 11/14/2006 39 Female 219 lb 11/17/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 1/24/2006 Male 176 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Life Threatening 63 Female 11/13/2006 Consumer United Kingdom
Primary
Concomitant
Urticaria Other Serious 8/2/2006 57 Male 190 lb 9/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/10/2006 58 Male 166 lb 11/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 12/12/2006 47 Male 168 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Other Serious 2/21/2007 51 Female 3/20/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/7/2007 53 Female 327 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypersomnia Hospitalization 11/4/2006 61 Male 278 lb 4/12/2007 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 11/4/2006 58 Male 259 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Sleep Paralysis Other Serious 3/29/2007 182 lb 5/4/2007 Consumer United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 10/13/2000 Male 5/7/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Other Serious 2/12/2007 55 Male 158 lb 11/14/2007 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 11/7/2007 56 Male 12/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 11/7/2007 56 Male 12/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 7/1/2003 Female 5/12/2008 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/29/2008 Male 5/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wrong Drug Administered Hospitalization 4/23/2008 79 Female 108 lb 5/15/2008 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/19/2008 79 Female 128 lb 7/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/19/2008 79 Female 128 lb 7/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Hospitalization 6/19/2008 73 Female 128 lb 7/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Hospitalization 6/19/2008 73 Female 128 lb 7/21/2008 United Kingdom
Primary
Concomitant
Platelet Count Increased Hospitalization 6/19/2008 73 Female 128 lb 7/24/2008 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 8/28/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 9/5/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 11/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 11/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 11/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 12/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/6/2008 54 Female 12/11/2008 Consumer United States
Primary
Concomitant
Neck Pain Other Serious 12/6/2008 54 Female 12/23/2008 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 1/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 12/18/2007 57 Female 152 lb 1/9/2009 Pharmacist United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Emphysema Other Serious 1/17/2009 72 Female 2/17/2009 Pharmacist Germany
Primary
Concomitant
Sleep Disorder Other Serious 1/12/2009 67 Female 143 lb 2/17/2009 Pharmacist Germany
Primary
Concomitant
Condition Aggravated Other Serious 1/19/2009 Male 157 lb 2/26/2009 Consumer Canada
Primary
Concomitant
Productive Cough Other Serious 1/6/2009 115 lb 3/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 3/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 4/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/10/2009 United Kingdom
Primary
Concomitant
Productive Cough Other Serious 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/19/2002 50 Male 211 lb 4/20/2009 United States
Primary
Concomitant
Gastrointestinal Pain 2/7/2008 54 Female 218 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Nightmare 7/25/2007 58 Male 176 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 5/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2001 42 Male 240 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 8/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebellar Infarction Death 73 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 9/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2008 Female 215 lb 9/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 10/1/2009 67 Male 11/13/2009 Consumer United Kingdom
Primary
Concomitant
Breast Abscess Other Serious 54 Female 196 lb 12/11/2009 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 73 Male 139 lb 2/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Breast Abscess Other Serious 11/1/2005 54 Female 196 lb 3/18/2010 Physician United Kingdom
Primary
Concomitant
Breast Abscess Other Serious 54 Female 196 lb 3/22/2010 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/4/2008 52 Male 157 lb 5/14/2010 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 4/3/2010 55 Male 182 lb 6/9/2010 Other Health Professional United States
Primary
Concomitant
Tangentiality Hospitalization 4/3/2010 55 Male 182 lb 6/9/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Ulceration Other Serious 2/1/2010 69 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/26/2010 65 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Platelet Count Increased Hospitalization 6/19/2008 73 Female 6/30/2010 Physician United Kingdom
Primary
Concomitant
Vision Blurred 3/1/2007 67 Male 7/12/2010 Consumer United States
Primary
Concomitant
Thrombophlebitis Other Serious 3/1/2008 52 Male 157 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 3/5/2009 55 Male 183 lb 10/7/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 12/18/2007 65 Male 159 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Male 229 lb 11/20/2010 Consumer
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 9/29/2010 66 Female 143 lb 11/24/2010 Physician New Zealand
Primary
Secondary
Concomitant
Nervousness 10/1/2010 55 Female 161 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Chills Other Serious 3/1/2008 52 Male 157 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Disability 1/24/2011 77 Female 187 lb 2/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Disability 1/24/2011 77 Female 187 lb 2/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Female 254 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Blindness Transient Hospitalization 3/1/2011 49 Female 201 lb 4/6/2011 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/1/2011 49 Female 201 lb 4/25/2011 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/1/2011 49 Female 201 lb 4/29/2011 Consumer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/1/2008 46 Male 5/5/2011 Lawyer United States
Primary
Concomitant
Hallucination, Auditory Hospitalization 9/1/2007 50 Male 5/5/2011 Lawyer United States
Primary
Concomitant
Renal Mass Hospitalization 2/22/2011 72 Male 5/25/2011 Physician United Kingdom
Primary
Concomitant
Blindness Transient Other Serious 3/1/2011 49 Female 201 lb 5/27/2011 Consumer United States
Primary
Concomitant
Constipation Hospitalization 2/22/2011 72 Male 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 12/25/2009 63 Female 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Fall Other Serious 3/1/2011 49 Female 201 lb 6/24/2011 Consumer United States
Primary
Concomitant
Incorrect Drug Administration Duration Other Serious Male 7/25/2011 Consumer United Kingdom
Primary
Concomitant
Flushing 9/21/2010 64 Male 222 lb 8/5/2011 Consumer United States
Primary
Concomitant
Large Intestine Perforation Death 7/1/2011 52 Female 119 lb 9/12/2011 Physician United States
Primary
Concomitant
Head And Neck Cancer Hospitalization 8/1/2011 84 Male 9/20/2011 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 8/1/2011 74 Male 9/22/2011 Pharmacist United States
Primary
Concomitant
Dysphagia Other Serious 8/1/2011 84 Male 9/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Eye Pain Other Serious 1/1/2007 50 Male 155 lb 9/23/2011 Physician United States
Primary
Concomitant
Bronchospasm Hospitalization 8/1/2011 48 Female 9/26/2011 Consumer United States
Primary
Secondary
Concomitant
Generalised Erythema Hospitalization 9/14/2011 53 Male 10/8/2011 Physician Denmark
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 9/29/2010 66 Female 143 lb 10/17/2011 Physician New Zealand
Primary
Secondary
Concomitant
Exposed Bone In Jaw Other Serious 5/1/2007 41 Female 10/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Streptococcal Infection Other Serious 5/1/2007 41 Female 11/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 10/27/2011 56 Female 136 lb 11/14/2011 Physician United Kingdom
Primary
Concomitant
Intervertebral Disc Space Narrowing Other Serious 5/1/2007 41 Female 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Duodenitis Other Serious 5/1/2007 41 Female 11/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteolysis Other Serious 5/1/2007 41 Female 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Alcohol Interaction Other Serious 10/4/2011 63 Male 11/30/2011 Physician Sweden
Primary
Concomitant
Interacting
Chest Pain Life Threatening 10/30/2011 66 Female 12/2/2011 Pharmacist United Kingdom
Primary
Concomitant
Head Discomfort Life Threatening 10/30/2011 66 Female 12/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Oropharyngeal Pain Other Serious 8/1/2011 84 Male 12/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Life Threatening Male 134 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Intentional Drug Misuse Other Serious Female 152 lb 1/12/2012 Consumer Brazil
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2010 68 Female 160 lb 1/25/2012 Consumer Canada
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2010 68 Female 160 lb 1/25/2012 Physician Canada
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2010 68 Female 160 lb 2/1/2012 Physician Canada
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 5/1/2007 41 Female 2/9/2012 Physician United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 5/1/2007 41 Female 2/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data