Simvastatin combined with Tramadol Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Radiculopathy Hospitalization 11/1/2003 Male 231 lb 2/15/2006 Physician New Zealand
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 10/15/2005 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Cholangitis Hospitalization 76 Female 9/7/2007 United Kingdom
Primary
Concomitant
Spinal Fusion Surgery Hospitalization 1/1/2007 70 Male 209 lb 12/18/2007 Physician Germany
Primary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Paranoia Other Serious 7/8/2008 56 Female 7/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Disability 10/13/2008 Male 168 lb 11/7/2008 Other Health Professional United States
Primary
Concomitant
Meningitis Meningococcal Other Serious 10/1/2008 Male 176 lb 11/14/2008 United States
Primary
Concomitant
Meningitis Meningococcal Other Serious 10/1/2008 Male 176 lb 12/1/2008 United States
Primary
Concomitant
Osteonecrosis Disability 3/28/2008 83 Female 148 lb 11/26/2008 Physician United States
Primary
Concomitant
Drug Ineffective Male 255 lb 12/12/2008 United States
Primary
Concomitant
Nephrolithiasis 5/16/2008 Male 12/12/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 11/1/2005 Female 12/12/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 11/21/2008 Female 12/18/2008 Physician United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 12/6/2008 Male 1/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 12/10/2008 70 Male 1/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 12/1/2008 55 Male 210 lb 2/2/2009 United States
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 12/1/2008 70 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 4/2/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Haematuria Other Serious 9/15/2008 Male 176 lb 4/15/2009 United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/9/2009 4/17/2009 Pharmacist Netherlands
Primary
Secondary
Concomitant
Haematuria Other Serious 9/15/2008 Male 206 lb 4/27/2009 United Kingdom
Primary
Secondary
Concomitant
Malaise Required Intervention 5/13/2009 70 Female 6/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Restlessness Other Serious 1/1/2009 62 Male 7/22/2009 United Kingdom
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 8/1/2008 66 Female 8/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Life Threatening 7/17/2009 86 8/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 1/1/2009 76 Female 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 7/31/2009 88 Female 9/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 7/31/2009 88 Female 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious Male 10/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 11/12/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Tongue Blistering Other Serious 11/17/2009 52 Female 12/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Delirium Disability 10/5/2009 89 Male 12/4/2009 United Kingdom
Primary
Concomitant
Somnolence Other Serious 11/30/2007 81 Male 12/17/2009 United Kingdom
Primary
Concomitant
Arthritis Other Serious 2/11/2010 71 267 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Clot Syndrome Other Serious 11/1/2007 59 Male 139 lb 3/22/2010 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 57 Male 127 lb 4/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 57 Female 220 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 10/10/2009 58 Male 228 lb 4/28/2010 Physician United States
Primary
Secondary
Concomitant
White Clot Syndrome Other Serious 11/20/2007 59 Male 139 lb 6/15/2010 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/26/2010 79 Male 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 7/2/2010 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 12/31/2008 63 Male 195 lb 7/12/2010 United States
Primary
Concomitant
Oesophageal Stenosis Hospitalization 2/4/2010 67 Male 224 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 73 Female 7/12/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 50 Male 7/27/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2008 76 Female 100 lb 7/27/2010 Consumer United States
Primary
Concomitant
Medication Error 62 Female 7/30/2010 Consumer United States
Primary
Concomitant
Pancytopenia Life Threatening 5/26/2010 75 Male 8/2/2010 Consumer United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/18/2007 87 Female 150 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Mass Hospitalization 6/3/2010 55 Female 8/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 5/1/2010 Female 125 lb 8/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased 1/1/2008 60 Female 142 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 1/1/2008 67 Male 198 lb 8/3/2010 Consumer United States
Primary
Concomitant
Death Death Female 8/4/2010 Consumer United States
Primary
Concomitant
Impaired Work Ability Disability 7/21/2010 61 Female 120 lb 8/5/2010 Consumer United States
Primary
Concomitant
Vascular Insufficiency Disability 8/1/2009 52 Male 306 lb 8/6/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/1/2010 80 Male 169 lb 8/9/2010 Physician United States
Primary
Concomitant
Pallor Other Serious 8/2/2010 73 Male 8/13/2010 Physician Germany
Primary
Concomitant
Death Death Female 8/13/2010 Physician United States
Primary
Concomitant
Sedation Other Serious 7/21/2010 61 Female 120 lb 9/10/2010 Physician United States
Primary
Concomitant
Pancreatitis Relapsing Other Serious 1/1/1998 51 Male 179 lb 9/17/2010 United States
Primary
Concomitant
Myoclonus Other Serious 12/2/2009 90 Female 9/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/2/2009 90 Female 112 lb 9/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 90 Female 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Other Serious 9/13/2010 62 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9/13/2010 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 7/15/2010 57 Male 159 lb 10/12/2010 Physician Brazil
Primary
Concomitant
Pain In Extremity Other Serious 9/13/2010 62 Female 10/12/2010 Other Health Professional
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 6/28/2010 72 Male 200 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Faecaloma Hospitalization 7/29/2010 71 Female 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Jaundice Hospitalization 8/13/2010 54 Male 196 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Intracranial Life Threatening 9/17/2010 68 Male 203 lb 11/3/2010 Physician Germany
Primary
Concomitant
Interacting
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Tremor Disability 8/1/2010 87 Male 135 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Effusion Life Threatening 7/15/2010 57 Male 159 lb 11/20/2010 Physician Brazil
Primary
Concomitant
Subileus Hospitalization 7/29/2010 71 Female 11/23/2010 Physician Germany
Primary
Secondary
Concomitant
Parkinson's Disease Disability 8/1/2010 87 Male 135 lb 11/10/2010 Other Health Professional
Primary
Concomitant
Serotonin Syndrome Other Serious 10/1/2010 36 Male 11/23/2010 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Disability 10/1/2010 36 Male 11/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pericardial Effusion Life Threatening 7/15/2010 57 Male 159 lb 12/13/2010 Physician Brazil
Primary
Concomitant
Rash Pruritic 7/30/2009 12/14/2010 Consumer United States
Primary
Concomitant
Psoriasis 10/1/2009 12/14/2010 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Disability 10/6/2010 36 Male 11/29/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pain In Extremity 3/15/2010 12/19/2010 Physician United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 11/26/2010 69 Female 12/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness 6/19/2010 12/22/2010 Consumer United States
Primary
Concomitant
Vaginitis Bacterial 6/8/2010 12/22/2010 Physician United States
Primary
Concomitant
Myalgia 7/7/2010 12/22/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 11/26/2010 69 Female 12/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 11/26/2010 69 Female 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 11/26/2010 69 Female 12/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 1/1/2009 56 Female 1/10/2011 Physician United States
Primary
Secondary
Memory Impairment Hospitalization 11/29/2010 69 Female 12/22/2010 United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Ageusia Other Serious 1/5/2011 72 Female 190 lb 3/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ageusia Other Serious 1/5/2011 72 Female 3/21/2011 Other Health Professional Denmark
Primary
Concomitant
Neuropathy Peripheral Hospitalization 67 Female 4/21/2011 United States
Primary
Concomitant
Haematochezia Hospitalization 2/1/2011 81 Female 123 lb 5/7/2011 Consumer United States
Primary
Concomitant
Bone Disorder Hospitalization 1/1/2003 53 Female 5/12/2011 Consumer United States
Primary
Concomitant
Fall Other Serious 9/19/2010 84 Female 106 lb 5/6/2011 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 4/14/2011 67 Male 5/16/2011 Physician United Kingdom
Primary
Concomitant
Crying Disability Female 5/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/5/2011 77 Male 181 lb 5/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling 5/16/2011 95 Male 6/2/2011 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/8/2011 77 Male 179 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Glaucoma Other Serious 2/18/2010 Male 198 lb 6/15/2011 Physician Germany
Primary
Concomitant
Lobar Pneumonia Other Serious 3/18/2011 75 Female 5/31/2011 Italy
Primary
Secondary
Concomitant
Drug Dose Omission Disability Female 6/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 1/1/2003 55 Male 247 lb 7/14/2011 Consumer Germany
Primary
Secondary
Concomitant
Glaucoma Other Serious 2/18/2010 Male 198 lb 8/15/2011 Physician Germany
Primary
Concomitant
Emotional Distress Other Serious 7/10/2011 71 Male 8/11/2011 Other Health Professional Denmark
Primary
Concomitant
Multiple Injuries Hospitalization 4/1/2010 52 Female 155 lb 9/2/2011 Consumer United States
Primary
Concomitant
Coombs Test Positive Hospitalization 4/27/2011 75 Female 220 lb 8/17/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 76 Male 176 lb 9/6/2011 Consumer Brazil
Primary
Concomitant
Balance Disorder Other Serious 8/1/2011 60 Male 190 lb 8/29/2011 Consumer United States
Primary
Secondary
Concomitant
Metastases To Liver Disability 7/19/2011 65 Female 9/5/2011 Physician United Kingdom
Primary
Concomitant
Metastases To Liver Disability 7/19/2011 65 Female 9/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Dose Omission Other Serious 11/22/2010 66 Female 164 lb 9/8/2011 Physician United States
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 63 Male 9/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Fatigue Life Threatening 2/1/2011 68 Female 185 lb 9/19/2011 Consumer Germany
Primary
Concomitant
Uterine Polyp Life Threatening 2/1/2011 68 Female 185 lb 9/21/2011 Consumer Germany
Primary
Concomitant
Hyperglycaemia Life Threatening 1/3/2009 67 Female 256 lb 9/27/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Myalgia Disability 9/22/2011 41 Female 267 lb 10/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/4/2011 77 Male 181 lb 10/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/8/2011 77 Male 180 lb 10/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 6/1/2011 52 Female 312 lb 10/6/2011 Physician United States
Primary
Concomitant
Myalgia Hospitalization 7/30/2011 76 Female 168 lb 11/7/2011 Physician Austria
Primary
Concomitant
Dyspnoea Death 10/4/2005 45 Female 164 lb 11/14/2011 Other Health Professional United States
Primary
Concomitant
Weight Decreased Life Threatening 2/1/2011 68 Female 185 lb 11/23/2011 Consumer Germany
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 6/1/2011 76 Female 174 lb 11/28/2011 Pharmacist Belgium
Primary
Concomitant
Sepsis Hospitalization 2/12/2010 56 Male 227 lb 11/29/2011 Physician Germany
Primary
Concomitant
Adverse Event Hospitalization 2/1/2011 68 Female 185 lb 11/29/2011 Consumer Germany
Primary
Concomitant
Jaundice Hospitalization 1/26/2010 79 Female 176 lb 12/2/2011 Physician Austria
Primary
Secondary
Concomitant
Hypoaesthesia 7/15/2011 50 Female 200 lb 9/8/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2011 68 Female 185 lb 12/21/2011 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 4/5/2010 73 Female 183 lb 12/29/2011 Physician Austria
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/5/2010 73 Female 183 lb 12/30/2011 Physician Austria
Primary
Concomitant
Knee Arthroplasty Death 4/5/2010 73 Female 183 lb 1/3/2012 Physician Austria
Primary
Concomitant
Colorectal Cancer Metastatic Life Threatening 11/8/2011 79 Female 187 lb 1/6/2012 Physician Netherlands
Primary
Secondary
Concomitant
Erythema Hospitalization 1/8/2012 53 Male 2/7/2012 Other Health Professional Finland
Primary
Concomitant

Drug Data