Cyclobenzaprine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oesophageal Spasm Hospitalization 5/22/2008 47 Female 295 lb 6/9/2008 United States
Primary
Concomitant
Pco2 Increased Hospitalization 5/19/2008 47 Female 294 lb 7/3/2008 United States
Primary
Concomitant
Product Quality Issue Hospitalization 7/1/2008 62 Female 180 lb 12/17/2008 Consumer United States
Primary
Concomitant
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 235 lb 3/6/2009 Physician United States
Primary
Concomitant
Drug Ineffective 1/1/2009 Female 3/14/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Required Intervention 3/19/2009 Female 3/26/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization Male 230 lb 4/9/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/30/2005 49 Female 268 lb 4/10/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Peptic Ulcer Hospitalization 1/1/2008 62 Female 195 lb 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Required Intervention 3/5/2009 53 Male 160 lb 4/10/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 54 Male 200 lb 4/16/2009 Consumer United States
Primary
Concomitant
Weight Increased Required Intervention 3/19/2009 Female 4/13/2009 Pharmacist United States
Primary
Concomitant
Eyelid Ptosis Other Serious 8/4/2008 Female 134 lb 5/5/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Vulvovaginal Pruritus Other Serious 12/1/2003 43 Female 134 lb 5/20/2009 United States
Primary
Concomitant
Weight Increased Required Intervention 3/19/2009 Female 5/20/2009 Pharmacist United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2000 48 Female 182 lb 6/25/2009 United States
Primary
Concomitant
Mania Other Serious 3/1/2009 Female 159 lb 6/26/2009 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 5/1/2009 72 Male 7/2/2009 Other Health Professional United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 11/1/2008 Female 160 lb 7/14/2009 United States
Primary
Concomitant
Agranulocytosis Life Threatening 5/24/2009 76 Male 198 lb 7/10/2009 Pharmacist United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 4/7/2004 54 Male 251 lb 7/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2005 32 Female 204 lb 7/17/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 8/6/1999 47 Male 232 lb 7/23/2009 United States
Primary
Concomitant
Mania Other Serious 3/1/2009 Female 159 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Hypertension Other Serious Male 260 lb 8/21/2009 Consumer United States
Primary
Concomitant
Interacting
Myalgia 4/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Generalised 4/16/2009 Male 248 lb 8/22/2009 United States
Primary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 8/20/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/19/2009 Male 181 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious 60 Male 260 lb 8/25/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 5/1/2008 69 Female 9/2/2009 Consumer United States
Primary
Secondary
Concomitant
Nocardiosis Hospitalization Female 9/10/2009 Physician United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Injury Death 64 Female 9/10/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection 7/31/2009 Female 180 lb 9/19/2009 Physician
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2004 45 Female 153 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 6/24/2002 46 Female 180 lb 9/23/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious Male 260 lb 9/24/2009 Consumer United States
Primary
Concomitant
Interacting
Wound Infection Death 56 Male 325 lb 9/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Erectile Dysfunction 9/1/2009 57 Male 12/9/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 77 Male 159 lb 12/18/2009 Lawyer United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/23/2005 Female 10/21/2009 Other Health Professional United States
Primary
Concomitant
Thrombophlebitis Hospitalization 11/1/2008 Male 214 lb 12/23/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Death 7/8/2009 53 Male 127 lb 12/29/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Wound Hospitalization 71 Male 1/11/2010 United States
Primary
Concomitant
Pain Hospitalization Female 1/14/2010 United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 59 Female 1/15/2010 United States
Primary
Concomitant
Injection Site Swelling 10/24/2009 Female 224 lb 1/30/2010 United States
Primary
Concomitant
Wound Hospitalization 71 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Injection Site Haematoma 12/15/2008 74 Female 134 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 77 Male 159 lb 3/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Insomnia United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2007 Male 3/16/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/12/2009 59 Female 77 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 3/23/2010 75 Female 4/9/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Post Procedural Stroke Hospitalization 5/20/2009 65 Male 130 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 82 Male 4/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 77 Male 159 lb 5/6/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Reaction To Drug Excipients Other Serious 11/1/2009 65 Female 168 lb 5/19/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2002 43 Male 6/1/2010 Physician United States
Primary
Concomitant
Nightmare 1/28/2010 40 Male 229 lb 6/8/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Visual Impairment United States
Primary
Secondary
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2010 65 Male 308 lb 7/1/2010 Physician United States
Primary
Concomitant
Throat Irritation 5/8/2008 69 Female 7/7/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Nausea 4/24/2007 61 Female 185 lb 7/13/2010 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 58 Male 183 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Toothache Other Serious 11/23/2005 75 Female 4/13/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 11/23/2005 75 Female 4/13/2010 Physician United States
Primary
Concomitant
Nausea 1/11/2009 48 Female 180 lb 7/23/2010 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage 1/1/2009 52 140 lb 7/27/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/29/2006 25 Female 229 lb 8/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 60 Female 142 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Thinking Abnormal Other Serious Female 153 lb 8/3/2010 Consumer United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/11/2010 38 Female 123 lb 8/13/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Disability 1/1/2010 64 Female 192 lb 7/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Swollen Tongue 1/2/2010 57 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Rash Macular 1/1/2010 38 Male 290 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 4/30/2010 53 Female 160 lb 8/29/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 63 Male 250 lb 8/31/2010 Physician United States
Primary
Concomitant
Sinusitis 2/1/2010 51 Female 175 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 7/1/2010 47 Female 260 lb 9/3/2010 Consumer United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/9/2010 Other Health Professional Canada
Primary
Concomitant
Suicide Attempt Other Serious 6/1/2007 41 Female 9/14/2010 Lawyer United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/20/2010 Other Health Professional Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 45 Female 155 lb 9/20/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 9/10/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 64 Male 144 lb 9/21/2010 United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/24/2010 Other Health Professional Canada
Primary
Concomitant
Injection Site Pain 7/1/2010 42 Female 9/24/2010 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 9/30/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2007 48 Male 238 lb 10/19/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2007 38 Female 123 lb 10/21/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/23/2010 49 Male 154 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 10/27/2010 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 6/28/2010 55 Female 174 lb 10/29/2010 Physician United States
Primary
Concomitant
Oropharyngeal Blistering 69 Female 10/13/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 3/1/2009 54 Female 11/10/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 9/20/2009 48 Male 201 lb 11/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 7/13/2010 52 Female 207 lb 11/12/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/15/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/19/2010 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/21/2010 56 Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2010 36 Female 300 lb 12/12/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 41 Male 287 lb 12/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Rash Pruritic 7/30/2009 12/14/2010 Consumer United States
Primary
Concomitant
Sinusitis Female 175 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2010 52 Male 12/16/2010 Other Health Professional United States
Primary
Concomitant
Exostosis Hospitalization 9/15/2010 50 Male 175 lb 12/27/2010 Consumer United States
Primary
Concomitant
Inflammation Other Serious 1/1/2011 Male 1/25/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data