Ketoconazole combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Arrhythmia Required Intervention 10/31/2005 58 Male 269 lb 10/31/2005 Pharmacist United States
Primary
Concomitant
Dysstasia Hospitalization 5/29/2006 64 Male 5/29/2006 Pharmacist United States
Primary
Secondary
Stasis Dermatitis Hospitalization 6/5/2006 Male 281 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 8/13/2006 70 Male 218 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2006 Male 175 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 7/17/2006 Male 204 lb 11/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/8/2006 54 Male 193 lb 12/20/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/2/2007 60 Male 205 lb 5/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/15/2007 59 Male 298 lb 3/17/2007 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Hospitalization 84 Male 5/25/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 84 Male 5/17/2007 United States
Primary
Secondary
Urticaria Required Intervention 7/15/2007 55 Male 175 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/17/2007 59 Male 8/27/2007 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Hospitalization 7/29/2007 83 Male 10/12/2007 Pharmacist United States
Primary
Secondary
Influenza Like Illness Other Serious 3/1/2007 Female 187 lb 4/17/2008 Denmark
Primary
Concomitant
Myositis Other Serious 6/11/2008 78 Male 7/10/2008 Physician United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 3/24/2008 70 Male 205 lb 7/15/2008 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/27/2009 Female 150 lb 4/13/2009 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/13/2008 Male 6/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/21/2009 Male 203 lb 6/30/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Myopathy Other Serious 61 Male 8/14/2009 Other Health Professional Australia
Primary
Interacting
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Vomiting 1/1/2004 41 Female 271 lb 9/23/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/9/2009 United States
Primary
Concomitant
Swelling Face Other Serious 1/15/2009 53 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Other Serious 6/11/2008 78 Male 10/23/2009 United Kingdom
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/27/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/4/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
Pyoderma Other Serious 2/23/2007 Male 2/22/2010 Other Health Professional United States
Primary
Concomitant
Sunburn Other Serious 2/23/2007 Male 3/8/2010 Other Health Professional United States
Primary
Concomitant
Sunburn Other Serious 2/23/2007 Male 3/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/16/2009 81 Male 199 lb 1/14/2010 Pharmacist United States
Primary
Secondary
Sunburn Other Serious 2/23/2007 45 Male 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/23/2007 45 Male 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 4/14/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 5/3/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/23/2007 45 Male 5/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/1/2010 47 Male 170 lb 5/18/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/23/2007 45 Male 6/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/23/2007 45 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/23/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 84 Male 8/12/2010 Physician United States
Primary
Secondary
Rhabdomyolysis Hospitalization 73 Male 8/12/2010 Physician United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 8/25/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/1/2010 47 Male 170 lb 9/16/2010 Other Health Professional United States
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 5/1/2007 Female 9/20/2010 United States
Primary
Concomitant
Melanocytic Naevus Hospitalization 1/1/2010 32 Male 243 lb 9/20/2010 Physician United States
Primary
Concomitant
Fungal Infection 8/1/2010 79 Male 168 lb 9/20/2010 Consumer United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 10/15/2010 United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 10/27/2010 United States
Primary
Concomitant
Melanocytic Naevus 1/1/2010 32 Male 243 lb 11/9/2010 Physician United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 11/11/2010 United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 11/23/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/1/2010 47 Male 170 lb 5/18/2010 Other Health Professional United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 12/28/2010 United States
Primary
Concomitant
Poor Venous Access Other Serious 3/13/2003 66 Male 174 lb 1/20/2011 United States
Primary
Concomitant
Prostatic Specific Antigen Increased 5/1/2009 67 Male 145 lb 1/23/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Infection Hospitalization 2/7/2010 57 Female 198 lb 1/30/2011 Consumer Netherlands
Primary
Concomitant
Psoriasis 8/1/2010 73 Male 195 lb 1/30/2011 Consumer United States
Primary
Concomitant
Dysphagia Other Serious 1/1/2003 46 Male 3/11/2011 Lawyer United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 54 Female 3/28/2011 Physician United States
Primary
Interacting
Rhabdomyolysis Other Serious 73 Male 3/28/2011 Physician United States
Primary
Interacting
Drug Interaction Other Serious 84 Male 3/28/2011 Physician United States
Primary
Interacting
Drug Interaction Hospitalization 1/1/2009 64 Male 3/29/2011 Physician United States
Primary
Secondary
Interacting
Meniscus Lesion Other Serious 1/1/2007 50 Male 3/29/2011 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 73 Male 3/29/2011 Physician United States
Primary
Interacting
Drug Interaction Other Serious 54 Female 3/29/2011 Physician United States
Primary
Interacting
Drug Interaction Other Serious 84 Male 3/29/2011 Physician United States
Primary
Interacting
Gingival Bleeding Disability 1/1/2003 46 Male 3/29/2011 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/13/2003 66 Male 174 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Bladder Discomfort Other Serious 1/1/2007 50 Male 4/8/2011 Physician United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 1/1/2009 39 Female 238 lb 3/21/2011 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 54 Female 4/11/2011 Other Health Professional Israel
Primary
Interacting
Contraindication To Medical Treatment Other Serious 73 Male 4/11/2011 Other Health Professional Israel
Primary
Interacting
Off Label Use Other Serious 73 Male 4/11/2011 Physician United States
Primary
Interacting
Drug Interaction Other Serious 54 Female 4/11/2011 Physician United States
Primary
Interacting
Drug Interaction Other Serious 84 Male 4/11/2011 Physician United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 3/22/2011 73 Male 231 lb 4/1/2011 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Other Serious 84 Male 4/13/2011 Physician United States
Primary
Concomitant
Interacting
Influenza Like Illness Hospitalization 54 Female 4/13/2011 Other Health Professional Israel
Primary
Interacting
Drug Interaction Hospitalization 73 Male 4/13/2011 Other Health Professional Israel
Primary
Interacting
Intervertebral Disc Degeneration Other Serious 1/1/2009 39 Female 232 lb 4/26/2011 Consumer United States
Primary
Concomitant
Patellofemoral Pain Syndrome Other Serious 2/13/2004 47 Male 6/1/2011 Other Health Professional United States
Primary
Concomitant
Ear Discomfort Other Serious 1/1/2009 66 Female 6/28/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Drug Interaction Other Serious 73 Male 6/29/2011 Other Health Professional United States
Primary
Secondary
Flushing 78 Female 147 lb 6/30/2011 Physician United States
Primary
Concomitant
Hypoacusis Other Serious 1/1/2009 66 Female 7/6/2011 Other Health Professional Denmark
Primary
Secondary
Dermal Cyst Other Serious 4/23/2004 65 Male 224 lb 7/11/2011 Other Health Professional United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 4/23/2004 65 Male 224 lb 7/19/2011 Other Health Professional United States
Primary
Concomitant
Initial Insomnia Other Serious 1/1/2009 39 Female 232 lb 7/13/2011 Consumer United States
Primary
Concomitant
Dermal Cyst Other Serious 4/23/2004 65 Male 224 lb 8/8/2011 Lawyer United States
Primary
Concomitant
Osteoarthritis Other Serious Male 8/30/2011 Other Health Professional United States
Primary
Concomitant
Tooth Abscess 7/1/2011 53 Male 9/6/2011 Physician United States
Primary
Concomitant
Aortic Valve Sclerosis Other Serious Male 9/7/2011 Other Health Professional United States
Primary
Concomitant
Asthenia Other Serious 11/5/2004 42 Male 9/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Aortic Valve Incompetence Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Headache Hospitalization 70 Female 11/1/2011 Other Health Professional Portugal
Primary
Interacting
Asthenia Hospitalization 70 Female 11/9/2011 Other Health Professional Portugal
Primary
Interacting
Renal Failure Acute Other Serious 70 Female 11/8/2011 Other Health Professional Portugal
Primary
Secondary
Concomitant
Bone Lesion Other Serious 4/23/2004 65 Male 224 lb 11/16/2011 Lawyer United States
Primary
Concomitant
Ligament Rupture Other Serious 2/13/2004 47 Male 11/16/2011 Physician United States
Primary
Concomitant
Myalgia Hospitalization 70 Female 11/23/2011 Other Health Professional Portugal
Primary
Interacting
Liver Disorder Other Serious 70 Female 12/6/2011 Other Health Professional Portugal
Primary
Interacting
Drug Interaction Other Serious 70 Female 12/6/2011 Other Health Professional Portugal
Primary
Interacting
Confusional State Hospitalization 70 Female 12/12/2011 Physician Portugal
Primary
Secondary
Drug Interaction Hospitalization 70 Female 12/13/2011 Other Health Professional Portugal
Primary
Secondary
Depression Hospitalization 56 Male 300 lb 11/23/2011 Lawyer United States
Primary
Concomitant
Gingival Recession Other Serious 4/23/2004 65 Male 224 lb 12/20/2011 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 70 Female 12/27/2011 Other Health Professional Portugal
Primary
Secondary
Atrial Flutter Hospitalization 12/14/2011 74 Male 198 lb 12/29/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Affective Disorder Other Serious 4/23/2004 65 Male 224 lb 12/30/2011 Other Health Professional United States
Primary
Concomitant
Bone Lesion Other Serious 4/23/2004 65 Male 224 lb 1/17/2012 United States
Primary
Concomitant
Atrial Flutter Hospitalization 12/14/2011 74 Male 190 lb 1/18/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious Male 2/6/2012 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Male 2/6/2012 Lawyer United States
Primary
Concomitant
Drug Interaction Disability 70 Female 2/7/2012 Other Health Professional Portugal
Primary
Secondary
Drug Interaction Other Serious 77 Male 2/24/2012 Other Health Professional United States
Primary
Secondary
Interacting
Economic Problem Hospitalization 5/1/2010 66 Female 160 lb 3/6/2012 Lawyer United States
Primary
Concomitant
Drug Interaction Other Serious 59 Male 3/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Bone Lesion Other Serious 4/23/2004 65 Male 224 lb 4/30/2012 Other Health Professional United States
Primary
Concomitant
Rales Other Serious 54 Male 274 lb 4/30/2012 Consumer United States
Primary
Concomitant
Hyperplasia Other Serious Male 5/28/2012 Consumer United States
Primary
Concomitant
Tooth Abscess 7/20/2011 54 Male 238 lb 6/14/2012 Physician United States
Primary
Concomitant
Drug Intolerance Other Serious 6/11/2012 70 Male 201 lb 6/30/2012 Physician United Kingdom
Primary
Concomitant
Drug Intolerance Other Serious 6/11/2012 70 Male 201 lb 7/5/2012 Physician United Kingdom
Primary
Concomitant
Muscle Fatigue Hospitalization 3/2/2012 46 Male 168 lb 7/6/2012 Physician Denmark
Primary
Concomitant
Fall Hospitalization 6/14/2012 75 Male 160 lb 6/26/2012 Consumer United States
Primary
Concomitant
Bradycardia Hospitalization 6/11/2012 70 Male 7/3/2012 Other Health Professional Denmark
Primary
Concomitant
Anaemia Death Male 7/17/2012 Physician United States
Primary
Concomitant
Toothache 8/6/2012 45 Female 238 lb 8/13/2012 Consumer United States
Primary
Concomitant
Gingival Recession Other Serious 4/23/2004 65 Male 224 lb 8/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Emphysema Other Serious Male 8/23/2012 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Hospitalization Male 10/25/2012 Consumer Us
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 6/14/2012 75 Male 160 lb 11/6/2012 Consumer Us
Primary
Concomitant
Toothache 8/6/2012 45 Female 238 lb 11/5/2012 Physician Us
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/20/2010 79 Male 188 lb 10/1/2012 Pharmacist Us
Primary
Secondary
Vulvovaginal Mycotic Infection 11/28/2011 46 Female 147 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Menstruation Irregular 46 Female 10/25/2012 Physician Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/4/2012 Consumer Country Not Specified
Primary
Concomitant

Drug Data