Simvastatin combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toothache Other Serious 9/2/2005 83 Male 3/15/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 73 Male 139 lb 4/13/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 73 Male 139 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2004 Female 4/28/2006 Physician Sweden
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2006 71 Female 114 lb 6/22/2006 Other Health Professional United States
Primary
Concomitant
Pollakiuria 73 Female 6/19/2006 Consumer United States
Primary
Concomitant
Tooth Resorption Other Serious 1/1/2005 70 Male 8/16/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/12/2006 71 Female 114 lb 9/9/2006 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious Female 220 lb 1/29/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Other Serious 10/11/2006 70 Male 3/1/2007 Physician Belgium
Primary
Concomitant
Renal Failure Life Threatening 3/14/2007 Male 198 lb 5/16/2007 Physician
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2005 70 Male 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 Female 8/29/2007 Physician United States
Primary
Concomitant
Peripheral Motor Neuropathy Hospitalization 12/1/2007 52 Male 198 lb 12/6/2007 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 10/2/2002 49 Female 128 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/14/2007 Male 198 lb 1/10/2008 Physician
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/2/2002 49 Female 128 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 11/22/2007 56 Female 143 lb 4/6/2008 Physician United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 3/1/2008 76 Male 192 lb 6/18/2008 Physician United States
Primary
Concomitant
Bone Disorder Required Intervention 3/26/2008 59 Female 4/8/2008 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Metastatic Other Serious Male 130 lb 7/17/2008 United States
Primary
Concomitant
Urinary Incontinence Other Serious 2/5/2007 69 Female 104 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Loose Tooth Other Serious Male 8/28/2008 Pharmacist Germany
Primary
Concomitant
Vomiting Hospitalization 3/6/2008 56 Female 9/5/2008 United States
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2007 Male 9/25/2008 Physician Germany
Primary
Concomitant
Osteonecrosis Disability 2/1/2008 Female 223 lb 10/14/2008 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 5/2/2007 65 Female 181 lb 10/22/2008 Physician Germany
Primary
Secondary
Concomitant
Bone Disorder Hospitalization 3/26/2008 59 Female 9/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/3/2008 58 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 Male 237 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 2/1/2008 Female 223 lb 11/5/2008 Other Health Professional France
Primary
Concomitant
Vision Blurred Other Serious 5/8/2008 Male 184 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Unknown 11/7/2008 Physician Brazil
Primary
Concomitant
Death Death 10/2/2008 11/26/2008 Physician Brazil
Primary
Concomitant
Tooth Extraction Other Serious 6/13/2007 Female 77 lb 12/3/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Hospitalization Male 12/9/2008 Physician United Kingdom
Primary
Concomitant
Colonoscopy Death 10/2/2008 12/5/2008 Physician Brazil
Primary
Concomitant
Osteonecrosis Other Serious 3/26/2008 59 Female 11/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 10/19/2008 84 Male 188 lb 11/20/2008 Pharmacist United States
Primary
Secondary
Vomiting Hospitalization 1/1/2008 Male 12/30/2008 Physician United States
Primary
Concomitant
Septic Shock Death 10/2/2008 12/23/2008 Physician Brazil
Primary
Concomitant
Tooth Extraction Other Serious 6/13/2007 Female 77 lb 1/2/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 1/30/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/16/2009 Male 2/5/2009 Pharmacist Canada
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 2/14/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 1/16/2009 Male 3/5/2009 Physician Canada
Primary
Concomitant
Urinary Incontinence Life Threatening 2/19/2007 69 Female 104 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Myxoedema Coma Other Serious Male 4/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myxoedema Coma Other Serious 1/1/2009 Male 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myxoedema Coma Other Serious 1/1/2009 Male 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2003 Female 5/21/2009 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 6/9/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 5/8/2008 Male 184 lb 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Open Fracture Other Serious 2/15/2008 Female 188 lb 6/19/2009 Physician Germany
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2003 Female 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myopathy Toxic Life Threatening 2/7/2008 68 Female 117 lb 7/10/2009 Physician Germany
Primary
Secondary
Concomitant
Speech Disorder Other Serious 2/6/2008 Female 185 lb 7/22/2009 Physician Germany
Primary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2003 Female 7/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myopathy Toxic Life Threatening 2/7/2008 68 Female 117 lb 7/31/2009 Physician Germany
Primary
Secondary
Troponin Increased Other Serious 1/1/2009 Female 117 lb 8/11/2009 United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2009 Female 117 lb 8/20/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 Male 233 lb 9/1/2009 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/21/2009 Male 174 lb 8/28/2009 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 Male 233 lb 9/2/2009 Consumer Brazil
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 5/1/2009 59 Female 9/9/2009 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2009 Female 117 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2003 Female 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 10/19/2009 Other Health Professional United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 4/9/2005 Female 100 lb 11/2/2009 Other Health Professional United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2009 Female 117 lb 11/6/2009 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/26/2009 Female 127 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious Female 11/9/2009 Consumer United States
Primary
Concomitant
Tooth Impacted Other Serious 4/9/2005 Female 100 lb 11/17/2009 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 11/24/2009 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/3/2009 Other Health Professional United States
Primary
Concomitant
Troponin I Increased Other Serious 1/1/2009 Female 119 lb 12/3/2009 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 12/14/2009 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/17/2009 Other Health Professional United States
Primary
Concomitant
Vena Cava Filter Insertion Hospitalization 4/9/1997 Female 131 lb 12/21/2009 Physician United States
Primary
Concomitant
Troponin I Increased Other Serious 1/1/2009 Female 119 lb 12/21/2009 United States
Primary
Secondary
Concomitant
Tooth Extraction Disability 2/21/2005 Male 1/4/2010 Other Health Professional Norway
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 1/18/2010 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 1/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/29/2001 Female 180 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/13/2010 85 Female 207 lb 2/9/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/29/2001 Female 180 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 2/11/2010 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 2/23/2004 Male 224 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/29/2001 Female 180 lb 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/24/2006 Male 2/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/29/2001 Female 180 lb 2/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 4/9/2005 Female 100 lb 2/23/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Repair Other Serious 4/7/2005 Male 3/1/2010 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2003 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/24/2006 Male 3/12/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 9/5/2006 Female 3/15/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 4/9/2005 Female 100 lb 3/17/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Tooth Repair Other Serious 4/7/2005 Male 3/19/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2003 Male 3/19/2010 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/5/2006 Female 3/23/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/24/2006 Male 3/24/2010 Other Health Professional United States
Primary
Concomitant
Tooth Repair Other Serious 4/7/2005 Male 3/26/2010 Other Health Professional United States
Primary
Concomitant
Vertebroplasty Other Serious 12/19/2003 Female 205 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 Male 224 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious Male 3/26/2010 Physician Netherlands
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/5/2006 Female 3/31/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 3/31/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/29/2001 72 Female 180 lb 4/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/6/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/22/2010 64 Male 4/7/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 64 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/29/2001 68 Female 180 lb 4/7/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 62 Male 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/24/2006 81 Male 4/11/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 4/14/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 4/14/2010 United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/2005 74 Female 100 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/15/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2006 54 Male 4/15/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/1/2003 64 Male 224 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 4/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/29/2009 73 Male 4/20/2010 Other Health Professional Netherlands
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/26/2010 United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 8/29/2001 68 Female 180 lb 4/28/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 5/3/2010 United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 5/4/2010 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant

Drug Data