Simvastatin combined with Trazodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 11/19/2005 Male 208 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 10/11/2005 79 Male Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 11/17/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 11/3/2005 77 Male 174 lb 12/7/2005 Pharmacist United States
Primary
Concomitant
Peripheral Vascular Disorder Death 84 Male 172 lb 12/22/2008 Physician United States
Primary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/9/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/21/2009 Physician United States
Primary
Concomitant
Blindness Other Serious Male 170 lb 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/24/2009 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 78 Female 3/25/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Yellow Skin 1/1/2008 Female 4/5/2009 Physician United States
Primary
Concomitant
Stent Placement Other Serious Male 170 lb 4/22/2009 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 4/9/2009 Male 319 lb 6/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Other Serious Male 170 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 9/11/2002 39 Female 107 lb 7/22/2009 United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Urine Odour Abnormal Other Serious 7/1/2009 Female 190 lb 8/21/2009 Consumer United States
Primary
Concomitant
Prurigo Other Serious 7/1/2009 55 Female 9/4/2009 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 6/1/2005 43 Female 9/7/2009 United States
Primary
Concomitant
Injection Site Haematoma 3/21/2007 Male 231 lb 9/11/2009 Consumer United States
Primary
Concomitant
Photophobia 1/1/2008 Female 233 lb 9/12/2009 Consumer United States
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/21/2008 Female 185 lb 9/12/2009 Physician United States
Primary
Concomitant
Incorrect Dose Administered 7/18/2008 Male 175 lb 9/12/2009 Consumer United States
Primary
Concomitant
Skin Papilloma Female 127 lb 9/18/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 8/1/2009 Female 9/19/2009 United States
Primary
Concomitant
Hypertension 5/6/2003 41 Female 267 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 49 Male 144 lb 9/23/2009 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 Female 148 lb 9/22/2009 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious Male 210 lb 9/23/2009 United States
Primary
Concomitant
Vision Blurred 1/1/2006 43 Male 180 lb 9/23/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2005 51 Female 194 lb 9/23/2009 United States
Primary
Concomitant
Vomiting 3/1/2004 42 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Pain Other Serious 5/6/2005 Female 9/25/2009 Other Health Professional Canada
Primary
Concomitant
Shock Other Serious 12/1/2007 71 Male 9/30/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/9/2004 51 Male 207 lb 10/8/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 44 Male 262 lb 10/14/2009 United States
Primary
Concomitant
Pericarditis Other Serious 12/3/2004 50 Female 159 lb 10/14/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Male 286 lb 10/15/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2008 Female 260 lb 10/15/2009 Physician United States
Primary
Concomitant
Vomiting Disability 5/1/2009 45 Female 243 lb 10/21/2009 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 65 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 Female 148 lb 11/2/2009 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/1/2008 Female 187 lb 12/1/2009 Consumer United States
Primary
Concomitant
Superficial Injury Of Eye 10/1/2009 Male 154 lb 12/7/2009 Consumer
Primary
Concomitant
Platelet Count Decreased Other Serious 10/30/2007 82 Female 165 lb 12/7/2009 Lawyer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 12/8/2009 United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 7/1/2009 Female 200 lb 12/31/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2008 Male 1/14/2010 Consumer United States
Primary
Concomitant
Osteopenia 1/1/2004 Male 1/20/2010 Consumer
Primary
Concomitant
Pain Other Serious 5/6/2005 Female 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Drug Ineffective Life Threatening 1/10/2010 Male 214 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 11/12/2009 Female 173 lb 1/27/2010 Physician United States
Primary
Concomitant
Nausea Hospitalization 12/1/2009 Female 190 lb 1/29/2010 United States
Primary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/1/2010 Physician United States
Primary
Concomitant
Dermatitis Bullous 3/1/2008 Male 175 lb 2/1/2010 United States
Primary
Concomitant
Drug Ineffective 8/15/2009 65 Male 2/4/2010 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 12/17/2009 Female 2/5/2010 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/10/2010 Physician United States
Primary
Concomitant
Ear Pain Other Serious Female 2/15/2010 Pharmacist United Kingdom
Primary
Concomitant
Parkinson's Disease Other Serious 2/1/2010 80 Female 182 lb 2/8/2010 Physician United States
Primary
Concomitant
Pain Other Serious 5/6/2005 Female 2/17/2010 Other Health Professional Canada
Primary
Concomitant
Coronary Artery Occlusion Other Serious 1/1/2008 78 Female 135 lb 2/22/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/18/2010 Female 191 lb 3/25/2010 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 3/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 51 Female 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Pruritus 3/10/2010 74 Male 249 lb 4/12/2010 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 84 Female 4/13/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 7/18/2009 60 Female 319 lb 4/15/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Male 194 lb 4/22/2010 Physician United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 8/20/2009 72 Female 176 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 5/6/2005 61 Female 5/13/2010 Other Health Professional Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Death 7/18/2009 60 Female 319 lb 5/14/2010 United States
Primary
Concomitant
Pelvic Fracture Other Serious 3/8/2010 60 Female 5/12/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/2/2010 77 Male 170 lb 6/14/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 5/6/2005 61 Female 7/9/2010 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Male 194 lb 7/12/2010 Physician United States
Primary
Concomitant
Thyroid Cancer Hospitalization 9/1/2009 7/22/2010 Other Health Professional United States
Primary
Concomitant
Transient Global Amnesia Other Serious 4/1/2008 63 Male 240 lb 7/22/2010 Consumer United States
Primary
Concomitant
Nausea 7/2/2008 59 Female 165 lb 7/22/2010 Consumer United States
Primary
Concomitant
Convulsion Other Serious 4/15/2008 61 Male 332 lb 7/22/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 11/1/2008 64 Female 99 lb 7/23/2010 Consumer Brazil
Primary
Concomitant
Stress Other Serious 7/9/2008 57 Female 212 lb 7/23/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/11/2002 39 Female 107 lb 7/26/2010 United States
Primary
Concomitant
Coeliac Disease 5/25/2010 45 Female 7/27/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 10/2/2007 78 Male 7/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Sedation Hospitalization 4/26/2010 84 Male 211 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Restlessness Other Serious 1/1/2008 60 Female 187 lb 7/29/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2008 61 Male 152 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 59 Male 279 lb 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 56 Female 186 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 12/19/2003 53 Female 205 lb 7/28/2010 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 7/8/2010 72 Male 184 lb 7/29/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased 2/8/2009 65 Female 152 lb 8/3/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 6/14/2007 44 Female 8/4/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/11/2002 39 Female 107 lb 8/5/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 43 Female 148 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 9/16/2010 Physician United States
Primary
Concomitant
Personality Change Other Serious Male 145 lb 10/6/2010 Consumer United States
Primary
Concomitant
Joint Stiffness Other Serious 1/1/2010 52 Female 291 lb 10/11/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/6/2010 60 Female 170 lb 10/8/2010 Other Health Professional United States
Primary
Concomitant
Paranoia Other Serious 9/1/2009 58 Male 149 lb 10/19/2010 Consumer United States
Primary
Interacting
Hypotension Other Serious 9/3/2010 56 Female 209 lb 10/22/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 5/6/2005 61 Female 10/22/2010 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious Female 168 lb 10/22/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 9/13/2010 74 Male 10/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vitamin B12 Decreased 7/30/2007 75 Female 10/28/2010 Consumer
Primary
Concomitant
Alopecia Female 124 lb 10/28/2010 Physician United States
Primary
Concomitant
Insomnia Other Serious 7/21/2008 54 Male 10/29/2010 Lawyer United States
Primary
Concomitant
Vision Blurred 63 Male 10/13/2010 Consumer United States
Primary
Concomitant
Tongue Disorder 10/8/2010 63 Female 11/1/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Male 194 lb 11/5/2010 United States
Primary
Concomitant
Paranoia Other Serious 9/1/2009 58 Male 149 lb 10/26/2010 United States
Primary
Secondary
Diarrhoea 11/1/2010 81 Female 140 lb 11/5/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 58 Female 11/10/2010 Consumer United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Female 11/12/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Male 194 lb 11/23/2010 United States
Primary
Concomitant
Tremor Life Threatening Male 119 lb 11/23/2010 Consumer Brazil
Primary
Concomitant
Death Death Male 168 lb 11/23/2010 Other Health Professional Canada
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2010 64 Female 160 lb 11/23/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 3/12/2008 60 Male 175 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 50 Female 282 lb 11/24/2010 Other Health Professional United States
Primary
Concomitant
Laboratory Test Abnormal 11/18/2010 56 Male 174 lb 11/30/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 63 Female 225 lb 11/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2010 36 Female 300 lb 12/12/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 43 Female 148 lb 11/2/2009 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 61 Male 256 lb 6/1/2010 Physician United States
Primary
Concomitant
Hyperaemia Other Serious 60 Female 12/16/2010 Consumer Brazil
Primary
Secondary
Concomitant
Malaise 9/24/2010 53 Female 235 lb 11/6/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2010 67 Female 225 lb 12/20/2010 Consumer United States
Primary
Secondary
Concomitant
Hallucination, Auditory Other Serious 88 Male 12/6/2010 Other Health Professional United States
Primary
Concomitant
Tremor Required Intervention 68 Female 12/9/2010 Other Health Professional Germany
Primary
Concomitant
Tachycardia Hospitalization 6/29/2010 62 Female 131 lb 7/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Death Death Female 12/24/2010 Germany
Primary
Concomitant
Infection Hospitalization 12/6/2010 75 Male 139 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/26/2008 72 Male 194 lb 12/28/2010 United States
Primary
Concomitant
Hypersensitivity Other Serious 10/27/2010 60 Female 12/9/2010 Brazil
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2010 67 Female 225 lb 12/29/2010 Consumer United States
Primary
Secondary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/13/2010 74 Male 12/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Aphasia Hospitalization 12/10/2010 86 Female 12/29/2010 Consumer United States
Primary
Concomitant
Headache Other Serious 12/19/2003 53 Female 205 lb 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 60 Female 12/22/2010 Consumer Brazil
Primary
Secondary
Concomitant

Drug Data