Carvedilol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Arterial Stent Insertion Other Serious 11/25/2005 67 Male 159 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Other Serious 10/13/2004 76 Female 1/17/2006 Physician Brazil
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 11/25/2005 67 Male 159 lb 1/13/2006 Poland
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/13/2006 Physician Sweden
Primary
Concomitant
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/23/2006 Physician Sweden
Primary
Concomitant
Hypertension Hospitalization 4/27/2004 73 Female 154 lb 1/30/2006 Consumer Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 6/28/2005 Male 197 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 2/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Resuscitation Death 1/3/2005 59 Male 2/13/2006 Other Health Professional Sweden
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 2/13/2006 Japan
Primary
Concomitant
Movement Disorder Hospitalization 1/1/2005 40 Male 1/3/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Catheter Related Complication Other Serious 9/9/2003 77 Male 172 lb 3/14/2006 Consumer United States
Primary
Concomitant
Viral Infection Other Serious Male 168 lb 3/8/2006 United States
Primary
Secondary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 11/9/2005 49 Female 3/10/2006 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 71 Male 3/27/2006 Pharmacist United States
Primary
Concomitant
Diarrhoea Disability 1/12/2006 79 Female 143 lb 3/28/2006 Physician Portugal
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2005 67 Male 132 lb 3/31/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Neck Pain Death 2/16/2006 82 Male 205 lb 4/4/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 4/18/2006 77 Male 134 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Stress Ulcer Hospitalization 11/8/2005 49 Female 4/18/2006 Physician Japan
Primary
Concomitant
Hypotension Hospitalization 2/9/2006 82 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/6/2005 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Life Threatening 3/10/2006 71 Male 139 lb 5/16/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 71 Male 139 lb 5/19/2006 Physician United Kingdom
Primary
Concomitant
Hypothyroidism Life Threatening 6/19/2005 53 Male 242 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 7/5/2005 58 Male 201 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/7/2005 83 Male 165 lb 7/17/2006 Denmark
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 5/29/2006 64 Female 7/12/2006 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 150 lb 8/4/2006 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 7/16/2006 70 Male 8/11/2006 Physician Singapore
Primary
Concomitant
Therapeutic Response Delayed Life Threatening 3/27/2006 63 Male 174 lb 8/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Cardiac Arrest Death 9/13/2006 53 Female 353 lb 9/21/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/2/2006 82 Male 9/14/2006 Physician United Kingdom
Primary
Concomitant
Abdominal Discomfort Other Serious 7/10/2006 78 Male 180 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 148 lb 10/10/2006 Physician Germany
Primary
Concomitant
Cardiac Failure Hospitalization 67 Male 132 lb 10/5/2006 Poland
Primary
Secondary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/18/2006 Physician Germany
Primary
Concomitant
Confusional State Hospitalization 10/9/2006 Male 154 lb 10/19/2006 Physician Germany
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Required Intervention 8/23/2006 85 Male 160 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Swelling Required Intervention 8/13/2006 64 Male 242 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/26/2006 Physician Germany
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Wrong Drug Administered Hospitalization 3/1/2006 67 Male 348 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 11/25/2005 67 Male 159 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Peritonitis Other Serious Male 11/2/2006 Denmark
Primary
Concomitant
Renal Failure Required Intervention 11/7/2006 75 Male 254 lb 11/15/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 71 Male 139 lb 11/21/2006 Physician United Kingdom
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/10/2005 61 Female 11/30/2006 Brazil
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 11/10/2006 71 Male 247 lb 12/1/2006 Physician Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 4/26/2005 78 Female 154 lb 12/11/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 11/10/2003 71 Male 247 lb 12/12/2006 Physician Germany
Primary
Concomitant
Ischaemia Hospitalization 67 Male 132 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 8/28/2006 Male 152 lb 12/22/2006 Physician Germany
Primary
Concomitant
Tracheal Disorder Hospitalization 11/10/2006 71 Male 247 lb 12/18/2006 Physician Germany
Primary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Hypercalcaemia Hospitalization 8/28/2006 Male 152 lb 1/5/2007 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Cardiogenic Shock Death 3/11/2006 91 Male 154 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/30/2005 60 Male 134 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 67 Male 132 lb 1/5/2007 Poland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2004 73 Male 152 lb 1/10/2007 Consumer Brazil
Primary
Concomitant
Self-medication Other Serious 35 Male 154 lb 1/5/2007 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 8/31/2006 74 Male 1/11/2007 Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 1/22/2007 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 11/10/2006 58 Male 166 lb 11/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 67 Male 132 lb 1/29/2007 Poland
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 10/6/2006 77 Male 123 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/22/2007 Female 2/7/2007 Consumer Brazil
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 12/18/2006 74 Male 2/7/2007 Pharmacist United States
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 76 Male 2/12/2007 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2007 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2004 Male 3/1/2007 Consumer Germany
Primary
Concomitant
Hypotonia Hospitalization 10/26/2006 3/6/2007 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/29/2004 Male 3/6/2007
Primary
Secondary
Concomitant
Vertigo Hospitalization 3/29/2004 Male 3/7/2007
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/14/2006 51 Male 272 lb 3/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 87 Male 3/13/2007
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 2/16/2007 72 Female 3/19/2007 Physician Switzerland
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 76 Male 3/20/2007 Other Health Professional United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 2/16/2007 72 Female 4/10/2007 Physician Switzerland
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2004 Male 4/14/2007 Consumer Germany
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hypotonia Hospitalization 5/15/2006 70 Male 5/1/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 3/25/2007 67 Female 198 lb 5/7/2007 Other Health Professional Austria
Primary
Concomitant
Chest Pain Hospitalization 3/15/2007 Male 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 67 Male 196 lb 12/13/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 70 Male 12/13/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Hospitalization Male 220 lb 6/5/2007 Consumer France
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 1/1/2007 79 Female 146 lb 6/5/2007 Pharmacist United States
Primary
Concomitant
Syncope Life Threatening 4/29/2007 Male 254 lb 6/15/2007 Pharmacist United States
Primary
Concomitant
Stomatitis Life Threatening 4/2/2007 81 Male 220 lb 6/29/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/18/2007 67 Male 198 lb 7/11/2007 Other Health Professional Greece
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/18/2007 67 Male 198 lb 8/2/2007 Other Health Professional Greece
Primary
Secondary
Concomitant
Colon Neoplasm Hospitalization 8/3/2007 77 Male 8/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Refractory Anaemia Other Serious 1/1/2005 76 Male 9/19/2007 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/21/2004 Male 168 lb 9/25/2007 Physician United States
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/27/2007
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 62 Male 9/21/2007 Physician Germany
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 9/28/2007
Primary
Secondary
Concomitant
Pain In Extremity 4/5/2007 93 Female 119 lb 9/20/2007 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 3/27/2006 68 Male 150 lb 10/1/2007
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/23/2007 83 Male 9/27/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/11/2007 66 Male 206 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 79 Male 10/17/2007 Physician Switzerland
Primary
Concomitant
Pain In Extremity Other Serious 73 Male 10/22/2007 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 73 Male 10/19/2007 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 8/1/2007 65 Male 11/12/2007 Physician Korea, Republic Of
Primary
Concomitant
Pain In Extremity Hospitalization 11/4/2007 61 Male 11/19/2007 Consumer United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization 10/26/2007 81 Male 11/26/2007 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Hospitalization 10/31/2007 Female 11/22/2007 Pharmacist Brazil
Primary
Concomitant
Blood Glucose Decreased 8/6/2007 Female 252 lb 11/29/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 10/11/2007 Male 145 lb 10/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/1/2006 64 Male 12/14/2007 Consumer United States
Primary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Weight Increased Hospitalization 11/29/2007 65 Male 12/21/2007 Korea, Republic Of
Primary
Concomitant
Libido Decreased 60 Male 12/21/2007 United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 11/4/2007 61 Male 1/4/2008 Consumer United States
Primary
Secondary
Concomitant
Libido Decreased 60 Male 12/21/2007 United Kingdom
Primary
Concomitant
Sensory Disturbance Other Serious 1/6/2007 58 Female 132 lb 1/18/2008 Pharmacist France
Primary
Concomitant

Drug Data