Nifedipine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 3/1/2005 70 Male 1/12/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 11/19/2005 Male 208 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 12/19/2005 73 Male 207 lb 2/8/2006 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukopenia Hospitalization 8/21/2005 76 Male 160 lb 1/30/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 2/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2006 47 Male 2/23/2006 Brazil
Primary
Concomitant
Malaise Other Serious 2/11/2006 47 Male 2/23/2006 Brazil
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/26/2006 75 Male 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 2/28/2006 72 Male 3/22/2006 United States
Primary
Concomitant
Meningitis Bacterial Other Serious 2/11/2006 47 Male 3/31/2006 Other Health Professional Brazil
Primary
Concomitant
Sudden Death Death 3/1/2006 72 Male 4/7/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 3/1/1998 62 Female 4/20/2006 France
Primary
Concomitant
Troponin Increased Other Serious 3/13/2006 80 Male 163 lb 4/12/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Hospitalization 1/5/2006 67 Male 191 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Chest Pain Life Threatening 2/16/2006 84 Female 2/17/2006 Pharmacist United States
Primary
Concomitant
Troponin Increased Other Serious 3/13/2006 80 Male 163 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/18/2006 81 Female 148 lb 5/15/2006 United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2006 64 Male 284 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 5/15/2006 73 Male 6/2/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 2/16/2006 87 Male 144 lb 2/16/2006 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Other Serious 4/27/2006 70 Female 5/30/2006 United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/18/2006 81 Female 148 lb 6/2/2006 Netherlands
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 4/27/2006 70 Female 6/1/2006 United Kingdom
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/13/2005 43 Male 6/2/2006 Other Health Professional Brazil
Primary
Concomitant
Intestinal Obstruction Other Serious 4/27/2006 70 Female 6/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 5/15/2006 73 Male 6/16/2006 Consumer United States
Primary
Concomitant
Respiratory Distress Other Serious 5/15/2006 73 Male 6/22/2006 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Renal Failure Acute Other Serious 73 Male 6/29/2006 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 6/14/2006 61 Female 119 lb 7/5/2006 Japan
Primary
Concomitant
Tenosynovitis Other Serious 11/1/1994 56 Male 7/13/2006 France
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Vomiting Hospitalization 6/14/2006 61 Female 119 lb 7/24/2006 Other Health Professional Japan
Primary
Concomitant
Urinary Hesitation Hospitalization 7/29/2006 72 Male 219 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 4/27/2006 70 Female 7/31/2006 United Kingdom
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/16/2006 69 Male 9/1/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/16/2006 69 Male 9/11/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/18/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Radiation Oesophagitis Other Serious 12/23/2005 61 Male 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Required Intervention 1/22/2006 78 Male 166 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 3/17/2006 29 Male 9/22/2006 Other Health Professional Brazil
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 3/31/2006 64 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2006 88 Male 9/30/2006 United States
Primary
Concomitant
Death Death 12/27/2005 Male 10/13/2006 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 72 Male 174 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hypokalaemia Disability 66 Male 10/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oliguria Hospitalization 12/1/2005 59 Female 10/16/2006 Other Health Professional Sweden
Primary
Secondary
Oliguria Hospitalization 12/1/2005 59 Female 10/23/2006 Other Health Professional Switzerland
Primary
Secondary
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Ventricular Dysfunction Other Serious 58 Male 10/27/2006 United Kingdom
Primary
Concomitant
Hypokalaemia Disability 66 Male 10/30/2006 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/8/2006 81 Female 11/7/2006 Consumer United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 52 Female 11/13/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Drug Ineffective Other Serious 9/1/2006 Female 11/7/2006 United States
Primary
Concomitant
Renal Failure Required Intervention 11/7/2006 75 Male 254 lb 11/15/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 9/15/2006 61 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Syncope Hospitalization 5/16/2006 90 Male 11/16/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/10/2005 61 Female 11/30/2006 Brazil
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/23/2006 67 Female 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 12/27/2005 Male 12/22/2006 Consumer United States
Primary
Concomitant
Radiation Oesophagitis Hospitalization 12/23/2005 61 Male 12/29/2006 United States
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 1/1/2005 72 Male 174 lb 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angioedema Other Serious 11/14/2006 76 Male 220 lb 11/14/2006 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Other Serious Male 1/26/2007 Lawyer United States
Primary
Concomitant
Testicular Pain Other Serious Male 2/6/2007 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Other Serious 1/1/2005 Male 265 lb 2/15/2007 Other Health Professional Netherlands
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/5/2006 Male 191 lb 3/5/2007 United States
Primary
Concomitant
Vocal Cord Thickening Hospitalization 8/28/2003 Male 172 lb 3/23/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Throat Tightness 10/1/2006 67 Female 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mental Status Changes Hospitalization 4/7/2007 92 Male 159 lb 4/20/2007 Pharmacist United States
Primary
Concomitant
Swollen Tongue Hospitalization 4/15/2007 59 Male 245 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence 3/9/2007 73 Female 230 lb 5/3/2007 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2006 Male 6/7/2007 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/23/2007 64 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Renal Disorder Other Serious 3/17/2006 Male 160 lb 6/14/2007 Physician Brazil
Primary
Concomitant
Hypersensitivity 10/1/2006 67 Female 4/10/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 115 lb 6/29/2007 Physician United States
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 6/29/2007 Consumer Brazil
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 7/13/2007 Consumer Brazil
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 7/6/2007 79 Male 7/26/2007 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious Male 8/8/2007 Lawyer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Life Threatening 5/13/2007 71 Male 8/15/2007 Physician Germany
Primary
Concomitant
Drug Interaction Other Serious 64 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Diarrhoea Other Serious 1/1/2006 81 Male 8/16/2007 Consumer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Life Threatening 5/13/2007 71 Male 8/20/2007 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 11/1/2006 79 Male 159 lb 8/21/2007 United Kingdom
Primary
Concomitant
Vitamin B12 Deficiency Life Threatening 6/28/2007 88 Male 153 lb 8/24/2007 Physician United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 1/1/2002 Female 154 lb 8/27/2007 Consumer Brazil
Primary
Concomitant
Staphylococcal Scalded Skin Syndrome Hospitalization 5/8/2007 55 Male 8/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 11/1/2006 79 Male 159 lb 8/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/18/2006 81 Female 148 lb 8/28/2007 Netherlands
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 58 Male 203 lb 9/13/2007 United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 58 Male 203 lb 9/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Other Serious 47 Female 10/1/2007 United States
Primary
Secondary
Concomitant
Trigeminal Neuralgia Hospitalization 6/26/2007 57 Female 9/28/2007 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 1/1/2006 81 Male 10/5/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 47 Female 10/2/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 65 Male 10/24/2007 Consumer United States
Primary
Concomitant
Vitamin B12 Deficiency Disability 3/1/2006 Male 10/24/2007 United Kingdom
Primary
Concomitant
Radiation Oesophagitis Hospitalization 12/23/2005 61 Male 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Self-injury Other Serious 4/1/2007 66 Male 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/5/2007 Germany
Primary
Concomitant
Diabetic Neuropathy 75 Male 11/7/2007 Consumer United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 1/1/2007 47 Female 11/7/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 2/4/2006 64 Female 11/8/2007 Physician United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization 12/17/2006 54 Male 108 lb 11/16/2007 Physician Singapore
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/26/2007 Germany
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 12/5/2007 Germany
Primary
Concomitant
Nephrotic Syndrome Other Serious 24 Male 12/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Toe Amputation Hospitalization 3/1/2007 Female 112 lb 12/27/2007 United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 58 Male 203 lb 12/20/2007
Primary
Concomitant
Diabetes Mellitus Other Serious 12/23/2006 73 Male 152 lb 12/28/2007 Physician Belgium
Primary
Concomitant
Erectile Dysfunction 9/1/2007 64 Male 1/2/2008 Other Health Professional United States
Primary
Concomitant
Fall Hospitalization 4/27/2007 Male 159 lb 1/21/2008 United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious 11/29/2007 46 Female 1/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/19/2005 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 1/1/2006 81 Male 2/4/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/25/2006 74 Female 1/22/2008 Australia
Primary
Secondary
Splenomegaly Hospitalization 7/6/2007 Male 2/5/2008 Physician United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pharmaceutical Product Complaint Other Serious 12/27/2007 81 Female 1/28/2008 Portugal
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Coronary Artery Occlusion Hospitalization 6/28/2007 80 Male 12/3/2007 Consumer United States
Primary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Laboratory Test Abnormal 11/26/2007 88 Female 107 lb 11/26/2007 Other Health Professional United States
Primary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/28/2008 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/16/2008 71 Female 209 lb 2/29/2008 Physician Germany
Primary
Concomitant
Speech Disorder Hospitalization Male 168 lb 2/29/2008 Brazil
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 2/1/2008 68 Male 3/17/2008 Physician Malaysia
Primary
Concomitant
Renal Failure Acute Life Threatening 11/3/2007 51 Male 245 lb 3/12/2008 Pharmacist United States
Primary
Secondary
Concomitant
Medication Error Other Serious 12/27/2007 81 Female 3/5/2008 Portugal
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/16/2008 71 Female 209 lb 3/26/2008 Physician Germany
Primary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 88 Male 4/7/2008 Physician United States
Primary
Concomitant

Drug Data