Simvastatin combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myelodysplastic Syndrome Other Serious 9/1/2004 Male 227 lb 2/15/2006 France
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/1/2004 Male 227 lb 2/15/2006 France
Primary
Concomitant
Post Procedural Complication Hospitalization 5/28/2005 68 Female 2/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/8/2005 76 Female 3/1/2006 Physician Norway
Primary
Concomitant
Weight Decreased Hospitalization 2/9/2006 70 Male 170 lb 4/10/2006 Physician Canada
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/14/2006 Norway
Primary
Concomitant
Weight Decreased Life Threatening 11/1/2005 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/28/2006 Norway
Primary
Concomitant
Vestibular Neuronitis Other Serious 8/7/2001 74 Female 5/1/2006 Norway
Primary
Concomitant
Aortic Thrombosis Hospitalization 1/1/2005 65 Male 5/3/2006 Pharmacist Germany
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Therapy Non-responder Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 5/22/2006 78 Female 7/20/2006 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Rhabdomyolysis Death Male 154 lb 9/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subcorneal Pustular Dermatosis Hospitalization 6/1/2006 Female 11/6/2006 Other Health Professional Norway
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/26/2006 72 Male 11/28/2006 Pharmacist United Kingdom
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Uterine Atrophy Hospitalization 1/1/2006 73 Female 12/13/2006 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 11/1/2006 43 Female 182 lb 1/27/2007 Physician United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 1/14/2007 80 Male 2/8/2007 United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 1/14/2007 80 Male 2/19/2007 United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 181 lb 3/8/2007 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 179 lb 4/9/2007 Physician United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 11/1/2006 72 Male 185 lb 4/12/2007 Consumer Norway
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 4/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 5/4/2007 Other Health Professional Sweden
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Hospitalization 7/13/2006 Male 159 lb 5/9/2007 United Kingdom
Primary
Concomitant
Chest Pain Other Serious 12/1/2006 71 Female 5/18/2007 Physician United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 7/13/2006 Male 159 lb 5/25/2007 United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Life Threatening 61 Female 5/31/2007 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 53 Female 141 lb 6/15/2007 Pharmacist Germany
Primary
Concomitant
Tearfulness Other Serious 3/26/2007 69 Female 116 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 Female 168 lb 6/27/2007 Physician United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 75 Female 7/18/2007 Belgium
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2007 Female 168 lb 7/27/2007 Physician United Kingdom
Primary
Concomitant
Chest Pain Other Serious 12/1/2006 71 Female 8/1/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious Female 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 48 Male 8/21/2007 Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 8/21/2007 Consumer Germany
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 181 lb 9/7/2007 Physician Germany
Primary
Concomitant
Gastric Haemorrhage Other Serious Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 181 lb 10/4/2007 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/4/2007 Male 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Hospitalization 6/1/2007 87 Male 143 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 87 Male 143 lb 12/14/2007 Consumer Germany
Primary
Concomitant
Vomiting Other Serious 9/1/2004 43 Male 12/4/2007 Physician Canada
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 1/5/2008 Male 2/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2007 Male 126 lb 3/11/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 2/21/2008 3/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 2/18/2008 86 Female 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2007 Male 126 lb 3/18/2008 Other Health Professional Germany
Primary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143300 lb 3/14/2008 Physician Germany
Primary
Concomitant
Agranulocytosis Other Serious 8/31/2007 Male 3/28/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/21/2008 42 Female 132 lb 3/27/2008 Other Health Professional
Primary
Concomitant
Vomiting Other Serious 2/21/2008 4/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 3/1/2008 Female 194 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 4/24/2008 Male 151 lb 6/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/5/2008 Physician Sweden
Primary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/9/2008 Physician Sweden
Primary
Concomitant
Renal Failure Hospitalization 5/1/2007 87 Male 143 lb 6/11/2008 Consumer Germany
Primary
Concomitant
Circulatory Collapse Other Serious 2/21/2008 81 Male 7/9/2008 Consumer Germany
Primary
Concomitant
Blood Pressure Decreased Hospitalization 12/20/2007 85 Female 7/10/2008 Physician Sweden
Primary
Concomitant
Circulatory Collapse 2/21/2008 81 Male 7/22/2008 Consumer Germany
Primary
Concomitant
Malaise Hospitalization 6/18/2008 77 Male 7/25/2008 Other Health Professional Sweden
Primary
Concomitant
Rash Pruritic Hospitalization 7/16/2008 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious 8/1/2008 64 Male 140 lb 9/2/2008 Consumer United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 7/16/2008 64 Male 8/28/2008 United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 7/16/2008 64 Male 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 8/1/2008 59 Male 9/11/2008 Consumer United Kingdom
Primary
Secondary
Rash Macular Hospitalization 7/16/2008 64 Male 9/8/2008 United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 9/17/2008 83 Female 10/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 86 Female 10/10/2008 United Kingdom
Primary
Concomitant
Pain Other Serious 8/1/2008 Female 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 3/8/2008 66 Female 10/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Haemorrhage Other Serious 10/1/2008 82 Female 12/15/2008 Physician France
Primary
Secondary
Concomitant
Wound Haemorrhage Hospitalization 10/1/2008 82 Female 163 lb 12/19/2008 Consumer France
Primary
Secondary
Concomitant
Postmenopausal Haemorrhage Hospitalization 9/1/2008 12/19/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Postmenopausal Haemorrhage Hospitalization 9/1/2008 77 Female 12/24/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 11/29/2008 Male 12/18/2008 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 58 Female 1/28/2009 Physician United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization 12/3/2005 Male 159 lb 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/6/2008 Female 2/9/2009 Consumer United Kingdom
Primary
Concomitant
Somnolence Hospitalization 1/1/2008 58 Female 2/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 58 Female 2/5/2009 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/6/2008 Female 2/13/2009 Consumer United Kingdom
Primary
Concomitant
Paranoia Other Serious 1/12/2009 Female 309 lb 2/26/2009 Consumer United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 1/7/2009 79 Male 3/6/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 58 Male 3/10/2009 Physician New Zealand
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 1/1/2008 3/16/2009 Physician United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Female 159 lb 3/19/2009 Physician Denmark
Primary
Concomitant
Renal Impairment Hospitalization 2/28/2009 69 Female 3/20/2009 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 1/2/2009 78 Male 3/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Thrombocytopenia Life Threatening 3/1/2009 68 Male 198 lb 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Death 68 Male 198 lb 4/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 68 Male 198 lb 4/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 68 Male 198 lb 4/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/23/2009 Male 4/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchitis Hospitalization 2/18/2009 4/24/2009 Physician Sweden
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 5/1/2009 Pharmacist France
Primary
Concomitant
Syncope Hospitalization 1/6/2009 79 Female 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Syncope Other Serious 1/6/2009 79 Female 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 1/17/2009 79 Female 5/1/2009
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 5/11/2009 Pharmacist France
Primary
Concomitant
Syncope Death 79 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Other Serious 11/1/2008 57 Female 5/28/2009 Physician New Zealand
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/1/2009 91 Female 6/11/2009 Pharmacist United Kingdom
Primary
Concomitant
Pleuropericarditis Hospitalization 5/9/2009 65 Female 6/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/7/2009 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/8/2009 Physician Spain
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/18/2008 84 Female 7/10/2009 Physician Australia
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 3/1/2009 71 Male 7/14/2009 Pharmacist France
Primary
Concomitant

Drug Data