Simvastatin combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 11/19/2005 Male 208 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Tachycardia Other Serious 47 Female 2/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dystonia 2/20/2006 54 Male 3/14/2006 United Kingdom
Primary
Concomitant
Therapy Non-responder Other Serious 47 Female 3/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Myoclonus Death 4/15/2006 66 Male 214 lb 5/1/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 3/7/2006 57 Male 320 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/25/2006 59 Male 288 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 56 Male 290 lb 6/2/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/23/2006 Male 154 lb 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Perinephric Effusion Other Serious 1/1/2003 49 Male 7/6/2006 Physician United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased 5/22/2006 65 Female 301 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Oral Mucosal Blistering Hospitalization 8/29/2006 48 Male 202 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Skin Exfoliation Hospitalization 8/29/2006 48 Male 202 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Retroperitoneal Abscess Other Serious 5/23/2006 59 Female 233 lb 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Infusion Site Reaction Hospitalization 10/1/2006 70 Male 187 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 9/1/2006 67 Male 153 lb 1/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 12/12/2006 65 Male 229 lb 1/13/2007 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/28/2006 75 Male 170 lb 1/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Tongue Disorder Life Threatening 2/26/2007 47 Male 220 lb 3/1/2007 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 12/15/2006 42 Male 207 lb 4/10/2007 Physician
Primary
Concomitant
Staphylococcal Infection Death 2/15/2007 Male 132 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness 10/29/2007 64 Male 220 lb 11/13/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/29/2007 64 Male 220 lb 11/19/2007 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/29/2007 64 Male 220 lb 12/7/2007 United States
Primary
Concomitant
Ventricular Tachycardia Death 10/14/2007 37 Female 146 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 3/19/2008 74 Female 4/1/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Life Threatening 56 Male 289 lb 5/24/2006 United States
Primary
Concomitant
Tremor Other Serious 7/2/2007 79 Male 4/8/2008 Pharmacist United States
Primary
Concomitant
Tachypnoea Death 63 Male 5/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Male 6/13/2008 Physician Switzerland
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 63 Male 6/13/2008
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 62 Male 11/19/2008
Primary
Secondary
Concomitant
Tinnitus 1/1/2003 54 Female 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 7/25/2007 69 Male 11/28/2008 China
Primary
Concomitant
Urinary Bladder Haemorrhage Other Serious 11/12/2008 Male 240 lb 12/1/2008 Other Health Professional United States
Primary
Concomitant
Death Death 9/15/2008 Male 12/5/2008 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 10/2/2008 82 Female 12/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Toxic Death 10/2/2008 82 Female 167 lb 12/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/5/2008 78 Male 1/9/2009 Pharmacist United States
Primary
Concomitant
Urinary Bladder Haemorrhage Other Serious 11/12/2008 Male 240 lb 2/5/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 10/10/2008 2/27/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Required Intervention 11/21/2008 44 Male 269 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 7/1/2008 Male 207 lb 3/9/2009 Pharmacist
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/9/2009 88 Male 181 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 69 Female 229 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 10/2/2008 82 Female 167 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 5/10/2009 78 6/10/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 69 Female 229 lb 6/4/2009 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 1/1/2009 69 Female 6/22/2009 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 4/2/2004 Female 220 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 1/13/2004 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Death 69 Female 229 lb 6/26/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Septic Embolus Required Intervention 76 Female 7/14/2009 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Rash Morbilliform Other Serious 7/27/2009 Female 170 lb 7/30/2009 Other Health Professional United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/12/2008 68 Male 175 lb 8/4/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2009 51 Male 245 lb 8/14/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 65 Male 190 lb 8/25/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 54 Male 381 lb 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2007 76 Male 198 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Nausea Life Threatening 3/10/2009 60 Female 9/21/2009 Physician Netherlands
Primary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 10/7/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 50 Female 10/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/1/2007 83 Female 159 lb 10/22/2009 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 74 Male 10/26/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 10/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/1/2007 76 Male 198 lb 11/17/2009 Other Health Professional United States
Primary
Concomitant
Pancreatic Necrosis Hospitalization 12/1/2008 63 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 72 Female 12/1/2009 Physician United States
Primary
Concomitant
Hospitalisation Other Serious 11/21/2009 62 Male 12/4/2009 Physician United States
Primary
Concomitant
Respiratory Distress Life Threatening 9/1/2007 69 Female 12/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 1/1/2009 62 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 8/24/2007 Female 157 lb 12/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/9/2009 61 Male 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Other Serious 63 Male 12/17/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/18/2009 Female 110 lb 10/19/2009 United States
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 10/22/2009 65 Male 116 lb 11/17/2009 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Required Intervention 10/6/2009 81 Male 201 lb 10/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 63 Male 12/21/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 54 Male 381 lb 1/7/2010 Lawyer United States
Primary
Concomitant
Thyroid Disorder Other Serious 11/1/2007 60 Male 227 lb 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 49 Female 128 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/1/2010 Physician United States
Primary
Concomitant
Pain Hospitalization 5/27/2008 Male 316 lb 2/10/2010 Physician United States
Primary
Concomitant
Vitrectomy Other Serious 3/1/2006 Male 2/10/2010 Physician United States
Primary
Concomitant
Surgery Hospitalization 2/3/2010 Male 2/12/2010 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Female 2/18/2010 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 2/7/2009 Female 121 lb 2/24/2010 United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious Male 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Other Serious 63 Male 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/7/2009 Female 121 lb 3/4/2010 United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Thrombosis In Device Life Threatening 1/1/2007 69 Female 143 lb 3/12/2010 Other Health Professional United States
Primary
Concomitant
Tooth Fracture Other Serious 10/3/2006 Male 3/12/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/11/2010 53 Male 305 lb 1/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 10/3/2006 Male 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 2/18/2010 Female 191 lb 3/25/2010 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 10/1/2007 Male 3/31/2010 Other Health Professional Norway
Primary
Concomitant
Interacting
Walking Aid User Other Serious 10/3/2006 Male 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 12/21/2008 49 Male 385 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Death 66 Male 4/6/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Post Procedural Stroke Hospitalization 5/20/2009 65 Male 130 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/4/2008 52 Male 157 lb 5/14/2010 Lawyer United States
Primary
Concomitant

Drug Data