Ciprofloxacin combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Convulsion Life Threatening 12/17/2005 53 Male 1/13/2006 United Kingdom
Primary
Concomitant
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/9/2005 62 Male 1/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/15/2006 Physician Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/15/2006 Physician Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/16/2006 Physician Canada
Primary
Secondary
Concomitant
Hypertension Other Serious 3/1/2006 60 Female 4/25/2006 Pharmacist Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/6/2005 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Urosepsis Other Serious 4/16/2006 43 Female 5/19/2006 Other Health Professional Argentina
Primary
Concomitant
Convulsion Life Threatening 12/17/2005 53 Male 5/22/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/7/2005 83 Male 165 lb 7/17/2006 Denmark
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/10/2006 72 Male 8/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/10/2006 72 Male 8/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/10/2006 72 Male 8/23/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/10/2006 72 Male 8/16/2006 United Kingdom
Primary
Concomitant
Urticaria Required Intervention 1/14/2006 Male 163 lb 9/8/2006 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 71 Male 9/13/2006 Physician Norway
Primary
Concomitant
Urticaria Other Serious 1/14/2006 Male 163 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 71 Male 9/21/2006 Physician Norway
Primary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 9/11/2006 73 Male 10/18/2006 United Kingdom
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 7/16/2006 49 Male 176 lb 10/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/11/2006 73 Male 176 lb 10/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 11/3/2000 65 Male 11/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dysuria Disability 10/20/2006 42 Male 165 lb 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Disability 10/20/2006 42 Male 165 lb 12/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Disability 10/20/2006 42 Male 165 lb 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Disability 10/20/2006 42 Male 165 lb 12/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/7/2006 46 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Prostatic Operation Other Serious 11/1/2006 Male 1/26/2007 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 7/28/2006 75 Male 170 lb 1/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 9/6/2005 Male 1/30/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/26/2007 81 Female 2/20/2007
Primary
Concomitant
Skin Ulcer Hospitalization 59 Female 3/14/2007
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 4/29/2005 Female 208 lb 3/23/2007 Physician Brazil
Primary
Concomitant
Mental Impairment Hospitalization 11/26/2006 Female 289 lb 3/18/2007 Pharmacist United States
Primary
Concomitant
Death Other Serious 3/5/2007 Male 154 lb 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 2/9/2007 67 Female 231 lb 5/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 3/5/2007 79 Male 6/14/2007 United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 5/12/2007 86 Female 6/14/2007 United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 33 Female 6/18/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Staphylococcal Infection Death 3/5/2007 79 Male 6/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 5/12/2007 86 Female 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 6/1/2006 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Swelling Other Serious 3/22/2007 Male 171 lb 7/13/2007 Consumer United States
Primary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/1997 Female 7/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Podagra Other Serious 7/17/2007 46 Male 176 lb 8/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2007 64 Female 8/8/2007 Pharmacist United States
Primary
Concomitant
Troponin T Increased Life Threatening 4/3/2007 48 Female 165 lb 8/10/2007 Physician Philippines
Primary
Concomitant
Podagra Other Serious 7/17/2007 46 Male 8/16/2007 United Kingdom
Primary
Concomitant
Podagra Other Serious 7/17/2007 46 Male 176 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Podagra Other Serious 7/17/2007 46 Male 8/13/2007 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 5/16/1997 69 Female 8/30/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/9/2007 76 Female 152 lb 9/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/1/2007 Male 250 lb 10/3/2007 Physician United States
Primary
Concomitant
Drug Toxicity Other Serious 76 Female 10/19/2007 United Kingdom
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 5/8/2007 11/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Liver Transplant Hospitalization 11/12/2007 Other Health Professional Sweden
Primary
Secondary
Pneumonia Hospitalization 10/14/2004 46 Male 188 lb 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 10/21/2007 79 12/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Death 2/3/2008 69 Male 2/4/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/19/2008 Female 2/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/19/2008 81 Female 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Pseudoporphyria Other Serious 65 Male 2/29/2008 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 77 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 3/29/2008 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/1/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Male 6/13/2008 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 6/15/2008 61 Male 194 lb 6/25/2008 Pharmacist United States
Primary
Secondary
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 6/15/2008 63 Female 7/2/2008 United Kingdom
Primary
Concomitant
Tendonitis Other Serious 6/1/2008 70 Male 154 lb 7/10/2008 Physician Belgium
Primary
Concomitant
Tendonitis Other Serious 6/1/2008 70 Male 154 lb 7/11/2008 Physician Belgium
Primary
Concomitant
Respiratory Distress Life Threatening 4/16/2006 Female 159 lb 7/14/2008 Physician Argentina
Primary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Other Serious 62 Male 7/24/2008 Switzerland
Primary
Concomitant
Interacting
Rhodococcus Infection Hospitalization 8/12/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/7/2008 67 Male 143 lb 8/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tendonitis Other Serious 6/1/2008 70 Male 154 lb 8/14/2008 Physician Belgium
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/14/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/17/2008 77 Female 176 lb 8/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 8/1/2008 82 Female 8/28/2008 Consumer United States
Primary
Concomitant
Interacting
Pulmonary Oedema Death Unknown 8/22/2008 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/2/2007 65 Female 181 lb 10/22/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 Male 207 lb 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 10/31/2008 Physician Belgium
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 1/1/2006 65 Male 11/12/2008 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/1/2006 65 Male 11/13/2008 Other Health Professional United States
Primary
Concomitant
Subcutaneous Emphysema Other Serious 62 Male 11/19/2008
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 11/24/2008 Physician Belgium
Primary
Secondary
Concomitant
Infected Skin Ulcer Hospitalization 8/8/2008 12/14/2008 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 12/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Dyspnoea Other Serious 10/25/2008 75 Female 118 lb 12/29/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/23/2008 88 Male 176 lb 1/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/23/2008 88 Male 176 lb 1/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 77 Male 1/12/2009
Primary
Secondary
Tubulointerstitial Nephritis Hospitalization 11/7/2008 91 Female 1/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/23/2008 88 Male 1/7/2009 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 11/23/2008 88 Male 176 lb 1/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/23/2008 88 Male 176 lb 1/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Chronic Other Serious 11/15/2006 1/21/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/23/2008 88 Male 1/16/2009 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/23/2008 88 Male 1/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 65 Male 1/23/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/1/2008 Female 117 lb 1/30/2009 Physician Germany
Primary
Concomitant
Skin Fragility Other Serious 65 Male 1/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/17/2008 82 Female 2/16/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 1/1/2007 65 Male 2/20/2009 Physician United Kingdom
Primary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tendon Rupture Disability 12/26/2008 76 Male 161 lb 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 10/25/2008 75 Female 118 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 12/1/2008 Female 216 lb 2/27/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 10/10/2008 2/27/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 65 Male 2/19/2009 United Kingdom
Primary
Concomitant
Ototoxicity Hospitalization 10/10/2007 74 Female 146 lb 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 11/15/2006 269 lb 3/2/2009 Consumer United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 11/15/2006 269 lb 3/4/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 11/1/2006 65 Male 3/9/2009 Physician United States
Primary
Concomitant

Drug Data