Metronidazole combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 80 Female 2/21/2006 Physician United States
Primary
Concomitant
Swollen Tongue Life Threatening 82 Female 4/13/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 1/9/2004 71 Female 168 lb 4/27/2006 Consumer Canada
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 4/24/2006 49 Male 234 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 74 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/27/2006 62 Male 8/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 1/14/2006 Male 163 lb 9/8/2006 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/1/2006 71 Male 9/13/2006 Physician Norway
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/7/2006 88 Male 169 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Disability 7/24/2006 43 Male 148 lb 12/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Melaena Hospitalization 2/22/2007 68 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Tremor Other Serious 8/11/2006 82 Male 8/10/2007 Physician United Kingdom
Primary
Concomitant
Hypoaesthesia Hospitalization 8/14/2007 69 Male 9/25/2007
Primary
Concomitant
Hypoaesthesia Hospitalization 8/14/2007 69 Male 9/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/3/2007 64 Male 11/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Jaundice Other Serious 10/5/2007 56 Female 227 lb 11/15/2007
Primary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hepatitis Other Serious 10/5/2007 56 Female 227 lb 11/16/2007 United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Extrapyramidal Disorder Hospitalization 82 Male 12/3/2007
Primary
Secondary
Concomitant
Vomiting Other Serious 8/3/2007 2/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Death 63 Male 5/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Petechiae Required Intervention 3/24/2008 85 Female 137 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/17/2008 75 Female 176 lb 9/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Malaise Other Serious 9/18/2008 Male 11/19/2008 Physician United Kingdom
Primary
Concomitant
Nausea Required Intervention 6/9/2008 39 Male 163 lb 7/8/2008 United States
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/15/2008 63 Male 172 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Female 161 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Peptic Ulcer Hospitalization 1/1/2008 62 Female 195 lb 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2005 69 Male 12/4/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Required Intervention 2/1/2009 57 Female 163 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Wound Other Serious 4/6/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 3/25/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 5/24/2009 76 Male 198 lb 7/10/2009 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/5/2009 71 Female 175 lb 7/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Life Threatening 4/7/2009 84 Female 7/22/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 5/4/2009 84 Female 139 lb 7/28/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Sepsis Other Serious 6/29/2009 Male 8/7/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 66 Male 8/31/2009 Physician Portugal
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Respiratory Rate Increased Disability 8/26/2009 78 Female 96 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 66 Male 9/4/2009 Portugal
Primary
Secondary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Urinary Retention Other Serious 5/30/2009 Male 9/19/2009 Consumer
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Wheezing Required Intervention 7/23/2009 53 Male 253 lb 9/29/2009 United States
Primary
Secondary
Concomitant
Torticollis Hospitalization 6/1/2006 59 Female 213 lb 10/21/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 12/4/2008 Male 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/29/2009 78 Male 180 lb 11/19/2009 Consumer United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 9/6/2009 11/3/2009 United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 9/6/2009 58 Male 11/27/2009 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 12/10/2009 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2009 Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Tracheal Haemorrhage Other Serious 63 Male 12/17/2009 United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 63 Male 12/21/2009
Primary
Secondary
Concomitant
Torticollis Hospitalization 6/1/2006 59 Female 213 lb 12/30/2009 United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 Female 1/22/2010 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 4/7/2009 84 Female 139 lb 1/27/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 79 Male 1/21/2010 United States
Primary
Concomitant
Clostridium Difficile Colitis Life Threatening 4/7/2009 84 Female 2/5/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Mass Other Serious 10/12/2009 Female 161 lb 2/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/29/2009 50 Male 2/22/2010 Thailand
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Other Serious 63 Male 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Incorrect Route Of Drug Administration Male 3/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 66 Male 3/11/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/30/2010 70 Male 3/12/2010 Physician Germany
Primary
Concomitant
Renal Disorder Other Serious 1/8/2010 66 Female 116 lb 1/10/2010 Pharmacist United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Haemorrhage Other Serious 1/11/2010 55 Male 185 lb 3/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 70 Male 4/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 10/19/2009 86 Male 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 70 Male 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Male 5/6/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 5/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 5/20/2010 69 Male 176 lb 5/21/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 5/27/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2001 64 Female 6/1/2010 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 66 Male 6/2/2010 Physician Portugal
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/3/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 6/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Death 10/19/2009 86 Male 6/9/2010 United Kingdom
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 64 Female 6/16/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/11/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 2/1/2010 34 Female 6/16/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 6/7/2010 86 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/19/2010 72 Male 6/21/2010 Consumer United Kingdom
Primary
Concomitant
Depression 36 Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/16/2009 67 Male 168 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 4/28/2010 64 Male 7/7/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/14/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 2/18/2008 66 Female 227 lb 7/16/2010 Physician United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 12/30/2009 84 Female 159 lb 7/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 159 lb 7/28/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Pulmonary Arterial Hypertension Death Male 7/29/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia 5/26/2009 83 Female 158 lb 7/31/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/29/2006 25 Female 229 lb 8/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Tremor 6/28/2008 Female 8/3/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 12/30/2009 84 Female 8/4/2010 Other Health Professional Japan
Primary
Concomitant
Interacting

Drug Data