Simvastatin combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia 1/1/2006 54 Female 166 lb 7/12/2006 Consumer United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/18/2006 50 Female 10/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 9/14/2006 Female 10/31/2006 Physician Belgium
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 9/24/2006 66 Female 12/14/2006 Other Health Professional Spain
Primary
Concomitant
Interacting
Pneumonia Hospitalization 12/1/2005 52 Male 12/27/2006 Consumer United States
Primary
Concomitant
No Adverse Effect 6/1/2006 69 Male 1/29/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/1/2005 52 Male 3/1/2007 Physician United States
Primary
Concomitant
Insomnia 6/1/2006 52 Female 1/12/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2007 52 Female 135 lb 5/30/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 2/3/2007 Female 140 lb 6/27/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 28 Female 240 lb 6/19/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 68 Male 9/26/2007 Physician Germany
Primary
Concomitant
Neck Pain Hospitalization 7/11/2007 58 Female 267 lb 9/20/2007 Consumer United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2007 Female 219 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 1/1/2005 59 Female 10/23/2007 Pharmacist Canada
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/23/2007 48 Female 10/31/2007 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2004 43 Male 12/4/2007 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/23/2007 48 Female 11/2/2007 United States
Primary
Concomitant
Suicidal Ideation Life Threatening 1/15/2008 45 Female 237 lb 1/18/2008 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 148 lb 1/28/2008 Consumer United States
Primary
Concomitant
Pallor Other Serious 50 Male 2/21/2008 Physician Israel
Primary
Concomitant
Interacting
Weight Decreased Other Serious 68 Male 2/28/2008 Physician Germany
Primary
Concomitant
Oedema Peripheral 1/17/2007 28 Female 240 lb 2/28/2007 Consumer United States
Primary
Concomitant
Somnolence 2/1/2008 59 Female 209 lb 4/1/2008 Consumer Germany
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/11/2006 28 Female 240 lb 9/4/2007 Consumer United States
Primary
Concomitant
Self-injurious Ideation Other Serious Male 193 lb 4/10/2008 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/1/2008 Female 4/21/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Hospitalization 3/1/2008 Female 4/30/2008 Consumer United States
Primary
Concomitant
Somnolence 2/1/2008 59 Female 209 lb 6/12/2008 Consumer Germany
Primary
Secondary
Concomitant
Thinking Abnormal Hospitalization 3/1/2008 Female 6/17/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/2/2008 41 Male 6/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 7/1/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2008 Male 7/7/2008 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 6/30/2008 Male 188 lb 7/7/2008 Other Health Professional United States
Primary
Concomitant
Somnolence 2/1/2008 59 Female 209 lb 7/31/2008 Physician Germany
Primary
Secondary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 8/6/2008 United States
Primary
Concomitant
Weight Increased 47 Female 220 lb 9/23/2008 Consumer United States
Primary
Concomitant
Hair Growth Abnormal 9/1/2007 45 Female 9/23/2008 Consumer United States
Primary
Concomitant
Overdose Other Serious 1/1/2002 56 Female 9/18/2008 Physician United States
Primary
Concomitant
Overdose Other Serious 1/1/2002 56 Female 10/14/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2006 Male 245 lb 10/24/2008 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 3/1/2008 Female 10/29/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2008 Female 235 lb 11/11/2008 Consumer United States
Primary
Concomitant
Hemiparesis Other Serious 11/4/2008 Female 207 lb 12/1/2008 Pharmacist Netherlands
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Cough 9/12/2008 Female 150 lb 12/12/2008 United States
Primary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 Female 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 8/1/2008 21 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 1/21/2009 Physician Germany
Primary
Concomitant
Interacting
Syncope Life Threatening 7/2/2008 63 Female 1/26/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 121 lb 2/24/2009 Physician Germany
Primary
Concomitant
Interacting
Bipolar I Disorder Other Serious 2/1/2009 Female 3/10/2009 Consumer United States
Primary
Concomitant
Somnolence Other Serious 2/1/2009 Female 529 lb 3/23/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2008 Female 3/27/2009 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 6/11/2004 53 Male 204 lb 4/1/2009 United States
Primary
Secondary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 529 lb 4/14/2009 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 12/1/2008 85 127 lb 4/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Other Serious 12/1/2008 85 127 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 205 lb 4/24/2009 Consumer United States
Primary
Concomitant
Off Label Use 11/1/2008 44 Female 300 lb 4/1/2009 Consumer United States
Primary
Concomitant
Weight Decreased Required Intervention 8/11/2008 Male 172 lb 4/2/2009 Consumer United States
Primary
Concomitant
Death Death 3/30/2008 61 Female 5/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Disability 5/1/2009 45 Female 243 lb 6/9/2009 Consumer United States
Primary
Concomitant
Weight Increased 3/1/2009 Female 188 lb 6/12/2009 United States
Primary
Concomitant
Nausea 1/1/2009 45 Female 6/5/2009 Consumer United States
Primary
Concomitant
Dyspnoea 37 Female 456 lb 6/23/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/26/2008 76 Female 6/22/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 212 lb 7/10/2009 Consumer United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 212 lb 7/15/2009 Consumer United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2003 54 Female 294 lb 7/28/2009 United States
Primary
Concomitant
Renal Failure Other Serious 3/7/2008 Female 121 lb 7/30/2009 Physician Germany
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 2/1/2009 Female 214 lb 7/29/2009 Consumer United States
Primary
Concomitant
Dermatitis Bullous Other Serious 9/20/2008 Female 281 lb 8/5/2009 Physician United States
Primary
Concomitant
Palpitations 7/5/2009 51 Female 7/22/2009 Consumer United States
Primary
Concomitant
Medication Error Other Serious Male 8/20/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 214 lb 9/3/2009 Consumer United States
Primary
Concomitant
Colitis Hospitalization 8/22/2009 Female 123 lb 9/14/2009 Physician Spain
Primary
Secondary
Concomitant
Vomiting 1/1/2004 41 Female 271 lb 9/23/2009 United States
Primary
Concomitant
Metabolic Syndrome 5/17/2006 46 Male 260 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Disability 5/1/2009 45 Female 243 lb 10/21/2009 Consumer United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 8/22/2009 Female 123 lb 10/27/2009 Physician Spain
Primary
Secondary
Concomitant
Volvulus Life Threatening 8/22/2009 Female 123 lb 11/5/2009 Physician Spain
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/5/2002 53 Female 294 lb 11/17/2009 United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 3/1/2008 Female 12/1/2009 Physician United States
Primary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/4/2009 Physician Spain
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 9/3/2009 36 Female 172 lb 12/8/2009 Consumer United States
Primary
Concomitant
Dysarthria Male 12/9/2009 Other Health Professional United States
Primary
Concomitant
Hyperglycaemia 4/8/2008 64 Female 12/9/2009 Consumer United States
Primary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/21/2009 Physician Spain
Primary
Secondary
Concomitant
Ageusia 11/27/2009 52 Female 198 lb 12/16/2009 United States
Primary
Concomitant
Volvulus Hospitalization 8/22/2009 Female 123 lb 12/24/2009 Physician Spain
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
Volvulus Life Threatening 8/22/2009 Female 123 lb 1/6/2010 Physician Spain
Primary
Secondary
Concomitant
Syncope Hospitalization 46 Female 1/12/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2008 61 Male 224 lb 1/22/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 1/25/2010 United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 59 Female 1/15/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 11/1/2009 21 Male 132 lb 2/1/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 56 Male 224 lb 2/11/2010 United States
Primary
Concomitant
Renal Disorder Other Serious 9/3/2008 53 Female 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/5/2010 Female 140 lb 3/4/2010 Consumer United States
Primary
Secondary
Concomitant
Sphincter Of Oddi Dysfunction Other Serious 10/15/2008 Female 226 lb 3/19/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2010 36 Female 3/26/2010 United States
Primary
Concomitant
Renal Failure Chronic Other Serious Female 3/30/2010 United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 12/21/2008 49 Male 385 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 4/15/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 4/12/2008 31 Female 115 lb 4/30/2010 Lawyer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/13/2010 50 Female 161 lb 5/3/2010 Physician United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 5/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/12/2008 31 Female 115 lb 5/4/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 156 lb 5/14/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 49 Male 290 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 68 Male 6/25/2010 Consumer United States
Primary
Concomitant
Depression 36 Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Vulvovaginal Dryness Other Serious Female 128 lb 7/6/2010 Physician United States
Primary
Concomitant
Depression Other Serious 6/1/2010 62 Male 186 lb 7/7/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 250 lb 7/12/2010 United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 68 Male 7/16/2010 Consumer United States
Primary
Concomitant
Myopia 10/13/2007 41 Male 300 lb 7/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Screen Positive 11/15/2007 43 Female 160 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 3/19/2008 64 Female 153 lb 7/21/2010 Consumer United States
Primary
Concomitant
Dysgeusia Female 7/22/2010 Consumer United States
Primary
Concomitant
Medication Error 62 Female 7/30/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 38 Female 7/30/2010 Consumer United States
Primary
Concomitant
Pain 5/1/2009 78 Female 145 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 76 Female 190 lb 8/3/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 7/19/2010 70 Female 154 lb 8/5/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/2/2010 United States
Primary
Concomitant
Depression Other Serious 6/1/2010 62 Male 186 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/1/2009 42 Male 220 lb 8/18/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 58 Female 304 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Rash Macular 1/1/2010 38 Male 290 lb 8/28/2010 United States
Primary
Concomitant
Tremor Other Serious 7/19/2010 70 Female 154 lb 9/3/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 5/20/2010 62 Male 172 lb 8/17/2010 Pharmacist United States
Primary
Secondary
Unevaluable Event 9/1/2009 46 Male 208 lb 9/17/2010 Consumer United States
Primary
Concomitant
Dry Mouth 1/1/2009 58 Female 9/17/2010 Other Health Professional United States
Primary
Concomitant

Drug Data