Niacin combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperglycaemia Hospitalization 11/9/2005 62 Male 1/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dysgeusia 8/1/2005 69 Male 205 lb 1/5/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 57 Male 225 lb 3/6/2006 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Death 1/28/2006 63 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Urinary Incontinence 1/1/2005 62 Male 1/25/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/20/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Flushing Other Serious 3/10/2000 74 Male 214 lb 3/27/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/9/2006 76 Male 150 lb 3/7/2006 Pharmacist United States
Primary
Concomitant
Ulcer Other Serious 12/5/2005 73 Male 194 lb 12/6/2005 Other Health Professional United States
Primary
Concomitant
Rash Pruritic 4/10/2006 67 Male 238 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Thinking Abnormal 5/1/2006 64 Male 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Peptic Ulcer Haemorrhage Other Serious 1/1/2005 Male 155 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2006 Male 9/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myalgia Other Serious 8/8/2006 60 Male 201 lb 9/15/2006 Pharmacist United States
Primary
Concomitant
Milk-alkali Syndrome Hospitalization 37 Female 11/29/2006
Primary
Secondary
Concomitant
Milk-alkali Syndrome Hospitalization 37 Female 12/28/2006
Primary
Secondary
Concomitant
Skin Cancer Other Serious 72 Male 250 lb 1/8/2007 Consumer United States
Primary
Concomitant
Neurological Symptom Other Serious 72 Male 250 lb 1/9/2007 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 1/1/2006 59 Male 140 lb 1/11/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 59 Male 140 lb 1/18/2007 Other Health Professional United States
Primary
Concomitant
Lactic Acidosis Hospitalization 64 Male 1/22/2007 Physician United States
Primary
Concomitant
Post Procedural Haematoma Hospitalization 9/26/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Heart Rate Irregular 10/1/2006 60 Female 184 lb 1/12/2007 Consumer United States
Primary
Concomitant
Hypersomnia Hospitalization 11/4/2006 61 Male 278 lb 4/12/2007 Pharmacist United States
Primary
Concomitant
Tetany Other Serious 37 Female 4/26/2007 Other Health Professional United States
Primary
Concomitant
Tetany Other Serious 37 Female 4/26/2007 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/23/2006 69 Male 251 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Cough Other Serious 11/21/2006 58 Male 198 lb 11/22/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 64 Male 4/23/2007 Physician United States
Primary
Concomitant
Asthenia Hospitalization 3/22/2007 Male 153 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/1/2000 70 Male 148 lb 12/13/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/2/2006 68 Male 195 lb 2/14/2007 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 5/4/2007 77 Male 5/25/2007 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Hospitalization 5/17/2007 59 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Surgery Other Serious 1/1/2007 64 Female 8/8/2007 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 5/15/2007 67 Male 8/7/2007 Pharmacist United States
Primary
Secondary
Blood Glucose Increased Hospitalization 7/17/2007 83 Male 8/17/2007 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Prostate Cancer Hospitalization 3/1/2006 66 Male 9/25/2007 Consumer United States
Primary
Concomitant
Blindness Unilateral Other Serious 12/1/2006 69 Male 218 lb 10/11/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension 70 Male 11/13/2007 Consumer United States
Primary
Concomitant
Blindness Unilateral Other Serious 12/1/2006 69 Male 218 lb 11/20/2007 Physician United States
Primary
Concomitant
Myalgia Required Intervention 2/14/2007 82 Male 11/20/2007 Pharmacist United States
Primary
Secondary
Migraine Other Serious 1/1/2007 Male 220 lb 12/21/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/4/2007 79 Male 1/25/2008 United States
Primary
Concomitant
Migraine Other Serious 1/1/2007 Male 220 lb 3/5/2008 Physician United States
Primary
Concomitant
Interacting
Drug Ineffective 11/1/2007 Male 3/5/2008 Consumer United States
Primary
Concomitant
Personality Change Required Intervention 1/10/2003 81 Male 160 lb 3/3/2008 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/1/2008 86 Male 172 lb 4/13/2008 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 4/1/2008 63 Male 4/30/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Required Intervention 5/20/2008 0 Male 130 lb 5/27/2008 Pharmacist United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 2/29/2008 61 Male 4/30/2008 United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 6/27/2008 74 Male 6/30/2008 Pharmacist United States
Primary
Secondary
Middle Insomnia 11/1/2007 55 Male 225 lb 7/24/2008 Consumer United States
Primary
Concomitant
Nocturia 7/1/2008 87 Male 8/28/2008 Consumer United States
Primary
Concomitant
Haemoptysis Hospitalization 8/19/2008 68 Male 161 lb 9/3/2008 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 8/19/2008 68 Male 161 lb 9/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis 6/6/2008 Male 165 lb 9/12/2008 United States
Primary
Concomitant
Psoriasis Other Serious 11/24/2007 58 Male 3/21/2008 Physician United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 64 Female 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 9/9/2008 61 Male 10/15/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 1/1/2008 75 Male 10/9/2008 United States
Primary
Secondary
Gallbladder Disorder Hospitalization 9/9/2008 61 Male 10/23/2008 Consumer United States
Primary
Concomitant
Rash 8/26/2008 82 Male 244 lb 10/28/2008 Pharmacist United States
Primary
Secondary
Hypertension 10/10/2008 Male 11/3/2008 Pharmacist
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/1/2006 65 Male 11/12/2008 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 9/9/2008 61 Male 211 lb 11/12/2008 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/1/2006 65 Male 11/13/2008 Other Health Professional United States
Primary
Concomitant
Somnolence Male 11/13/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 7/16/2008 55 Male 218 lb 7/31/2008 Pharmacist United States
Primary
Concomitant
Pollakiuria Hospitalization 11/8/2008 63 Male 133 lb 11/18/2008 Pharmacist United States
Primary
Concomitant
Cellulitis 6/6/2008 Male 165 lb 12/12/2008 United States
Primary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 9/25/2008 84 Male 12/22/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2008 48 Male 205 lb 12/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2003 52 Male 282 lb 1/5/2009 Consumer United States
Primary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant
Oedema Hospitalization 1/1/2007 56 Male 261 lb 1/22/2009 Other Health Professional United States
Primary
Concomitant
Dry Mouth 1/1/2009 Male 1/23/2009 Consumer
Primary
Secondary
Concomitant
Nervousness 1/1/2009 Male 2/3/2009 Consumer
Primary
Secondary
Concomitant
Urticaria 11/22/2008 64 Male 236 lb 2/9/2009 Pharmacist United States
Primary
Secondary
Nervousness 1/1/2009 Male 2/17/2009 Consumer
Primary
Secondary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 2/25/2009 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 2/4/2009 74 Male 196 lb 2/23/2009 Other Health Professional United States
Primary
Concomitant
Product Quality Issue 2/10/2009 Male 233 lb 2/24/2009 Physician United States
Primary
Concomitant
Visual Impairment Male 2/27/2009 Consumer
Primary
Concomitant
Renal Failure Acute Hospitalization 2/19/2009 74 Male 196 lb 2/25/2009 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 11/1/2006 65 Male 3/9/2009 Physician United States
Primary
Concomitant
Skin Lesion Hospitalization 11/1/2006 65 Male 3/13/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/19/2009 54 Female 139 lb 3/17/2009 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 65 Male 3/18/2009 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 65 Male 3/19/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Male 3/24/2009 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 70 Male 3/20/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 65 Male 3/23/2009 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Other Serious 3/16/2009 Female 165 lb 3/27/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 65 Male 3/24/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 12/1/2002 55 Male 192 lb 4/3/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/8/2008 60 Male 191 lb 4/1/2009 Pharmacist United States
Primary
Secondary
Viral Infection Hospitalization Female 105 lb 4/30/2009 Consumer United States
Primary
Concomitant
Swollen Tongue Other Serious 3/25/2009 56 Female 5/8/2009 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Other Serious 3/25/2009 56 Female 5/11/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis 3/5/2009 53 Male 168 lb 5/13/2009 Pharmacist United States
Primary
Secondary
Viral Upper Respiratory Tract Infection Hospitalization 4/26/2000 35 Male 230 lb 5/20/2009 United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 65 Male 5/22/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/1/2007 Male 270 lb 5/26/2009 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 68 Male 6/4/2009 Physician United States
Primary
Concomitant
Injection Site Pain Male 195 lb 6/12/2009 Consumer United States
Primary
Concomitant
Ischaemic Cardiomyopathy Life Threatening 11/1/2007 Male 270 lb 6/11/2009 Consumer United States
Primary
Concomitant
Product Quality Issue 1/27/2009 74 Male 6/25/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization Female 7/16/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 2/18/2005 53 Male 235 lb 7/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 8/4/2009 Male 180 lb 8/13/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Life Threatening Male 266 lb Physician United States
Primary
Secondary
Concomitant
Flushing 2/2/2009 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/22/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased 9/10/2008 Male 8/22/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/16/2009 51 Female 8/23/2009 Pharmacist United States
Primary
Secondary
Infection Other Serious 7/29/2009 Female 126 lb 8/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Cessation Other Serious 1/1/2009 55 Female 8/26/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2001 58 Male 267 lb 8/28/2009 United States
Primary
Concomitant
Infection Other Serious 7/29/2009 Female 126 lb 9/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 7/29/2009 Female 126 lb 9/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 4/1/2009 Male 9/25/2009 Consumer
Primary
Concomitant
Occult Blood Positive Hospitalization 8/10/2009 74 Male 159 lb 8/11/2009 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 7/22/2009 Female 9/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 59 Female 157 lb 9/30/2009 United States
Primary
Concomitant
Urinary Incontinence Other Serious 59 Female 157 lb 10/2/2009 United States
Primary
Concomitant
Drug Ineffective 4/27/2009 Male 10/7/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Female 157 lb 10/7/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Male 286 lb 10/15/2009 United States
Primary
Concomitant
Wrist Fracture Death 1/31/2006 79 Male 162 lb 10/9/2009 United States
Primary
Concomitant
Tremor Other Serious 59 Female 157 lb 10/21/2009 Physician United States
Primary
Concomitant
Interacting
Tremor Other Serious 59 Female 157 lb 10/22/2009
Primary
Secondary
Wrist Fracture Death 1/31/2006 79 Male 162 lb 10/26/2009 United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2007 59 Female 157 lb 11/5/2009 United States
Primary
Secondary
Concomitant
Tremor Other Serious 59 Female 157 lb 11/10/2009 Physician United States
Primary
Concomitant
Interacting
Viral Diarrhoea Hospitalization 10/9/2009 75 Male 189 lb 11/6/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 11/16/2009 83 Male 135 lb 11/23/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Other Serious 1/1/2005 Female 156 lb 11/24/2009 Consumer United States
Primary
Concomitant
Penis Disorder Required Intervention 4/29/2009 43 Male 185 lb 11/30/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/1/2009 54 Male 297 lb 11/18/2009 Pharmacist United States
Primary
Secondary
Tremor Other Serious 59 Female 157 lb 12/7/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Wound Dehiscence Other Serious 6/1/2009 78 Male 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 59 Female 157 lb 12/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Open Wound 6/15/2008 66 Male 12/11/2009 Consumer United States
Primary
Concomitant
Weight Increased 7/16/2009 51 Male 209 lb 12/9/2009 Consumer United States
Primary
Concomitant
Lip Swelling Other Serious 12/11/2009 68 Male 12/17/2009 Consumer United States
Primary
Concomitant

Drug Data