Alprazolam combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 2/7/2005 68 Male 170 lb 10/31/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 75 Male 1/10/2006
Primary
Concomitant
Electrocardiogram Pr Prolongation Other Serious 75 Male 1/12/2006 Italy
Primary
Concomitant
Heart Rate Decreased Other Serious 75 Male 1/23/2006 Other Health Professional Italy
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/5/2006 Female 139 lb 2/3/2006 Portugal
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Therapy Non-responder Death 46 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Loss Of Consciousness Life Threatening 1/5/2006 Female 139 lb 2/17/2006 Portugal
Primary
Concomitant
Tremor Life Threatening 1/5/2006 Female 139 lb 2/17/2006 Other Health Professional Portugal
Primary
Concomitant
Scrotal Haematoma Hospitalization 11/28/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Other Serious 75 Male 2/23/2006 Physician Italy
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 11/6/2005 53 Male 12/27/2005 Consumer United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 1/1/2005 75 Male 4/14/2006 Italy
Primary
Concomitant
Syncope Other Serious 1/1/2005 75 Male 5/17/2006 Physician Italy
Primary
Concomitant
Dry Mouth Other Serious 6/21/2006 56 Male 277 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/2/2006 United States
Primary
Concomitant
Skin Swelling Other Serious 1/1/2006 77 Male 158 lb 7/19/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/6/2006 47 Male 4/18/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia Hospitalization 8/9/2006 69 Male 155 lb 8/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 7/9/2006 77 Female 8/28/2006 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Renal Failure Acute Other Serious 6/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Rash Generalised Other Serious 9/15/2006 53 Male 172 lb 9/25/2006 Other Health Professional United States
Primary
Concomitant
Serum Sickness Other Serious 11/29/2003 70 Male 234 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Required Intervention 8/13/2006 64 Male 242 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2006 54 Male 185 lb 10/27/2006 United States
Primary
Concomitant
Lip Disorder Other Serious 6/6/2006 65 Male 131 lb 7/28/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 11/17/2006 57 Female 211 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Alopecia Other Serious 11/30/2006 68 Female 12/18/2006 Physician
Primary
Concomitant
Alopecia Other Serious 11/30/2006 68 Female 12/28/2006 Physician
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 1/3/2007 Physician Austria
Primary
Concomitant
Renal Failure Acute Other Serious 11/7/2006 78 Male 1/10/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/7/2006 78 Male 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Dizziness Disability 12/16/2006 66 Male 1/20/2007 Physician Spain
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 1/25/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Cardiac Failure Other Serious 10/20/2006 88 Female 1/31/2007 Physician Australia
Primary
Concomitant
Weight Decreased Hospitalization 87 Male 2/7/2007 Physician Spain
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/16/2006 69 Male 170 lb 3/5/2007 Physician Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 87 Male 3/13/2007
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 3/13/2007 Physician Austria
Primary
Concomitant
Urine Output Decreased Hospitalization 2/26/2007 85 Male 204 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Umbilical Hernia Hospitalization 8/12/2006 37 Male 4/5/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Other Serious 1/1/2007 Female 298 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 241 lb 4/11/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/1/2007 45 Female 4/26/2007 United States
Primary
Concomitant
Rhinorrhoea 43 Female 2/16/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 12/30/2006 73 Male 5/10/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Haematoma Other Serious 5/1/2007 78 Female 5/31/2007 Physician France
Primary
Concomitant
Muscle Spasms 5/1/2006 63 Male 3/13/2007 Consumer United States
Primary
Concomitant
Rhinorrhoea 43 Female 5/17/2007 Pharmacist United States
Primary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/6/2007 Germany
Primary
Secondary
Concomitant
Tremor Hospitalization 75 Female 7/16/2007
Primary
Secondary
Concomitant
Tremor Other Serious 75 Female 7/18/2007 Belgium
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/17/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Violence-related Symptom Other Serious 7/14/2007 Female 155 lb 7/25/2007 Consumer United States
Primary
Concomitant
Swollen Tongue Required Intervention 72 Male 8/7/2007 United States
Primary
Concomitant
Violence-related Symptom Other Serious 7/14/2007 Female 155 lb 8/31/2007 Physician United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/7/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 9/19/2007 Physician Denmark
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/1/2007 Female 9/26/2007 Physician Spain
Primary
Concomitant
Cerebral Infarction Hospitalization 11/16/2006 69 Male 170 lb 10/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/27/2007 Consumer United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 251 lb 10/5/2007 Physician United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Viral Infection Hospitalization 2/22/2005 35 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Stomach Discomfort Other Serious 9/1/2007 Female 190 lb 10/12/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 Male 172 lb 10/15/2007 Consumer United States
Primary
Secondary
Concomitant
Sternal Fracture Other Serious 1/1/2007 Female 10/19/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2007 Female 187 lb 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 Female 187 lb 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2007 Female 11/7/2007 Physician United States
Primary
Concomitant
Swollen Tongue Required Intervention 72 Male 11/8/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 54 Male 165 lb 11/30/2007 Consumer Brazil
Primary
Secondary
Concomitant
Retching 3/1/2007 37 Female 10/9/2007 Consumer United States
Primary
Concomitant
Gastric Ulcer Hospitalization 69 Female 12/13/2007 Korea, Republic Of
Primary
Secondary
Concomitant
Pain In Extremity 85 Female 119 lb 12/21/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 7/17/2006 74 Female 1/9/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2007 Female 1/15/2008 Physician United States
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2006 74 Female 11/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Occlusion Other Serious 1/1/2004 80 Male 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 7/1/2004 77 Female 127 lb 11/29/2007 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 5/21/2007 76 Female 150 lb 12/3/2007 Consumer United States
Primary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Paranoia Other Serious 1/1/2008 Female 145 lb 2/15/2008 United States
Primary
Concomitant
Cardiac Failure Chronic Hospitalization 1/3/2008 80 Female 2/19/2008 Physician France
Primary
Concomitant
Convulsion Hospitalization 8/1/2007 64 Female 1/17/2008 United States
Primary
Secondary
Concomitant
Nervousness Other Serious 12/1/2007 Female 137 lb 2/27/2008 Consumer United States
Primary
Concomitant
Retching 3/1/2007 37 Female 1/10/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 151 lb 3/7/2008 United States
Primary
Concomitant
Inflammation Other Serious 11/1/2007 Male 161 lb 3/14/2008 Physician Belgium
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 151 lb 3/14/2008 United States
Primary
Concomitant
Tympanic Membrane Perforation Other Serious 12/25/2007 59 Male 3/19/2008 Lawyer United States
Primary
Concomitant
Nervousness Other Serious 12/1/2007 Female 137 lb 3/27/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/7/2008 76 Female 134 lb 3/28/2008 Greece
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 151 lb 4/4/2008 United States
Primary
Concomitant
Tremor Hospitalization 75 Female 4/4/2008 Belgium
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 4/23/2008 79 Female 108 lb 5/15/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/7/2008 Female 134 lb 5/21/2008 Greece
Primary
Concomitant
Rash Other Serious 11/1/2007 Male 185 lb 5/30/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 3/1/2008 65 Male 206 lb 5/21/2008 United States
Primary
Concomitant
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Mood Altered 3/1/2008 Male 180 lb 6/12/2008 United States
Primary
Concomitant
Photophobia 1/1/2008 Female 233 lb 6/13/2008 Consumer United States
Primary
Concomitant
Weight Fluctuation 1/1/2006 58 Male 190 lb 4/10/2008 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 4/23/2008 Female 6/24/2008 Belgium
Primary
Concomitant
Tympanometry Abnormal Other Serious 12/25/2007 59 Male 6/25/2008 Lawyer United States
Primary
Concomitant
Overdose 1/1/2007 60 Male 190 lb 4/10/2008 Consumer United States
Primary
Concomitant
Skin Disorder Life Threatening 1/1/2008 Female 292 lb 6/29/2008 Consumer United States
Primary
Concomitant
Skin Disorder Life Threatening 1/1/2008 Female 292 lb 7/14/2008 Consumer United States
Primary
Concomitant
Hallucination, Visual Hospitalization 9/6/2007 94 Female 193 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Respiratory Distress Hospitalization 6/12/2008 61 Female 7/22/2008 Pharmacist United States
Primary
Concomitant
Mental Impairment Other Serious 7/13/2008 Male 200 lb 7/25/2008 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 80 Male 163 lb 7/28/2008 Consumer Brazil
Primary
Secondary
Concomitant
Somnambulism Hospitalization 6/28/2008 Female 7/27/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 275 lb 7/28/2008 United States
Primary
Concomitant
Vomiting Hospitalization Female 275 lb 7/31/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 150 lb 8/18/2008 Consumer United States
Primary
Concomitant
Pruritus Generalised 4/1/2008 Female 150 lb 8/27/2008 Consumer United States
Primary
Concomitant
Throat Tightness 7/18/2008 Female 8/27/2008 United States
Primary
Concomitant
Pruritus Generalised 5/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 68 Female 9/9/2008 Pharmacist Spain
Primary
Concomitant
Interacting
Somnambulism Hospitalization 6/28/2008 Female 9/8/2008 Physician United States
Primary
Concomitant
Accidental Exposure Other Serious 11/1/2007 Female 94 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 1/23/2007 Female 280 lb 9/13/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 68 Male 177 lb 9/15/2008 Lawyer United States
Primary
Concomitant
Surgical Failure Hospitalization 6/28/2008 Female 9/11/2008 Physician United States
Primary
Concomitant
Tachycardia 8/2/2008 Female 9/29/2008 Consumer
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2006 Female 9/30/2008 United States
Primary
Concomitant
Quadriparesis Hospitalization 7/10/2008 Female 10/2/2008 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute 8/21/2008 56 Male 138 lb 10/16/2008 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization Female 194 lb 10/21/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/21/2008 53 Male 282 lb 10/22/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2008 78 Female 10/31/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/21/2008 53 Male 282 lb 11/3/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 10/26/2008 55 Male 10/31/2008 Physician United States
Primary
Concomitant

Drug Data