Simvastatin combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transient Ischaemic Attack Hospitalization 5/11/2002 73 Male 201 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 12/1/2005 81 Male 190 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Dysgeusia 1/1/2005 45 Female 160 lb 1/5/2006 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 9/5/2005 85 Female 100 lb 11/21/2005 Pharmacist United States
Primary
Concomitant
Vascular Calcification Hospitalization 4/19/2002 73 Male 201 lb 3/6/2006 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 40 Male 3/6/2006 Physician United Kingdom
Primary
Concomitant
Vascular Calcification Hospitalization 4/19/2002 73 Male 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Myalgia Hospitalization 3/1/2006 79 Female 5/19/2006 Physician Germany
Primary
Concomitant
Insomnia 3/13/2006 72 Female 146 lb 4/3/2006 Consumer United States
Primary
Concomitant
Muscle Injury Other Serious 6/5/2006 80 Male 180 lb 6/13/2006 Consumer United States
Primary
Concomitant
Spontaneous Penile Erection 12/28/2005 73 Male 4/25/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 4/1/2006 71 Female 130 lb 7/7/2006 Physician Germany
Primary
Secondary
Concomitant
Myalgia Life Threatening 4/23/2006 71 Female 130 lb 7/18/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/23/2006 71 Female 130 lb 7/20/2006 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 6/8/2006 63 Male 189 lb 6/26/2006 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 6/7/2006 Male 180 lb 7/27/2006 Physician United States
Primary
Concomitant
Spontaneous Penile Erection 12/28/2005 73 Male 6/28/2006 United States
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 150 lb 8/4/2006 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 7/16/2006 70 Male 8/11/2006 Physician Singapore
Primary
Concomitant
Wound Secretion Other Serious 2/16/2006 53 Male 8/14/2006 Lawyer United States
Primary
Concomitant
Haematochezia Hospitalization 7/6/2006 66 Female 9/15/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 148 lb 10/10/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/15/2006 69 Male 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 11/7/2006 52 Female 175 lb 11/22/2006 United States
Primary
Concomitant
Nausea 10/20/2006 Female 12/12/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/1/2006 Male 1/22/2007 Physician Germany
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 1/13/2007 72 Male 172 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/13/2007 72 Male 172 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Rash Disability 2/9/2007 73 Female 3/13/2007 Physician United States
Primary
Concomitant
No Therapeutic Response 7/1/2005 79 Female 179 lb 1/23/2007 Consumer United States
Primary
Concomitant
Insomnia 10/1/2006 79 Male 187 lb 1/12/2007 Consumer United States
Primary
Concomitant
Middle Insomnia 2/19/2006 74 Male 200 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 298 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Rash Disability 2/9/2007 73 Female 4/16/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 1/13/2007 Male 172 lb 4/20/2007 United States
Primary
Secondary
Concomitant
Throat Tightness Other Serious 3/1/2007 Female 145 lb 4/24/2007 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 1/9/2007 Male 198 lb 4/27/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/15/2006 69 Male 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 1/13/2007 72 Male 172 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 74 Male 200 lb 2/6/2007 United States
Primary
Concomitant
Dizziness 11/1/2006 82 Male 175 lb 2/28/2007 United States
Primary
Concomitant
Haematochezia Other Serious 12/1/2006 68 Female 170 lb 2/28/2007 United States
Primary
Concomitant
Nipple Pain 12/1/2006 66 Male 154 lb 4/12/2007 Consumer United States
Primary
Concomitant
Death Other Serious Male 6/8/2007 Physician Australia
Primary
Concomitant
Pneumonia Other Serious 10/1/2004 76 Male 6/11/2007 Consumer United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/23/2007 64 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Palpitations 4/16/2007 72 Female 204 lb 5/7/2007 Physician United States
Primary
Concomitant
Rash 3/29/2007 47 Male 5/7/2007 Pharmacist United States
Primary
Concomitant
Cardiac Disorder Hospitalization 57 Female 6/28/2007 Physician United States
Primary
Concomitant
Hepatocellular Damage Hospitalization 1/1/2007 63 Male 7/6/2007 Physician Germany
Primary
Concomitant
Jaundice Hospitalization 4/4/2006 78 Female 7/23/2007 Pharmacist United States
Primary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Hunger 3/1/2007 37 Female 7/11/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2005 Female 9/13/2007 Physician United States
Primary
Concomitant
Candida Sepsis Other Serious 2/6/2006 69 Male 245 lb 7/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 Female 187 lb 9/25/2007 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/21/2004 Male 168 lb 9/25/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2004 76 Male 10/23/2007 Consumer United States
Primary
Concomitant
Middle Insomnia 70 175 lb 10/5/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 10/24/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/8/2007 66 Female 174 lb 11/14/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2007 Female 240 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Eczema Hospitalization 11/7/2007 66 Male 176 lb 11/26/2007 Other Health Professional Denmark
Primary
Concomitant
Eczema Hospitalization 11/7/2007 66 Male 176 lb 11/29/2007 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 11/30/2007 Consumer United States
Primary
Concomitant
Postnasal Drip 11/16/2007 Male 12/12/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 12/21/2007 Consumer United States
Primary
Concomitant
Pruritus 10/12/2007 80 Male 12/27/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 12/28/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Blood Pressure Inadequately Controlled 12/1/2007 Male 174 lb 1/24/2008 Pharmacist United States
Primary
Concomitant
Rhinorrhoea 11/16/2007 Male 1/25/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 8/1/2007 2/7/2008 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 1/3/2008 75 Male 171 lb 1/20/2008 Physician United States
Primary
Secondary
Dizziness Required Intervention 11/22/2007 Female 1/25/2008 Pharmacist United States
Primary
Concomitant
Hypertension 1/1/2006 70 Female 1/10/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2006 68 Female 170 lb 3/14/2007 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Inadequately Controlled 12/1/2007 Male 174 lb 3/13/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 2/1/1997 50 Male 254 lb 3/26/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 4/10/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 3/1/2008 Female 4/10/2008 Pharmacist United States
Primary
Concomitant
Renal Pain Hospitalization Female 4/17/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 3/1/2008 Female 4/18/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 4/18/2008 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 2/13/2008 67 Female 4/29/2008 United States
Primary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 5/5/2008 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/1/2005 59 Female 5/6/2008 Physician United Kingdom
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 4/28/2008 60 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 5/8/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 5/23/2008 Consumer United States
Primary
Secondary
Concomitant
Contusion Male 6/5/2008 Consumer United States
Primary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Chromaturia Other Serious 1/7/2008 58 Female 205 lb 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 217 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Application Site Pruritus 6/15/2008 Female 7/28/2008 Consumer United States
Primary
Concomitant
Cholecystitis Infective Other Serious 46 Male 260 lb 7/18/2008 United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 6/20/2008 62 Male 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 4/1/2008 67 Female 7/7/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 8/28/2008 Consumer United States
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 5/15/2008 75 Male 209 lb 8/28/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 9/5/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2008 74 Female 179 lb 9/29/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 3/1/2008 Female 178 lb 10/3/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death Male 9/29/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 3/23/2008 Female 178 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 52 Male 10/15/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 149 lb 11/10/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 1/1/2008 74 Female 179 lb 11/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/22/2008 59 Male 256 lb 9/19/2008 United States
Primary
Concomitant
Drug Ineffective 78 Male 11/11/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution 51 Female 11/19/2008 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Life Threatening 8/23/2008 59 11/21/2008 Pharmacist United States
Primary
Concomitant
Pain In Extremity 9/1/2008 78 Male 11/14/2008 United States
Primary
Concomitant
Product Quality Issue Other Serious 11/1/2008 66 Female 165 lb 12/3/2008 Consumer United States
Primary
Concomitant
Heart Injury Other Serious 9/8/2006 58 Male 220 lb 12/11/2008 Consumer United States
Primary
Concomitant
Insomnia 6/25/2008 Female 12/13/2008 Physician United States
Primary
Concomitant
Cough Hospitalization 2/1/2008 76 Male 12/17/2008 Consumer United States
Primary
Concomitant
Nausea Male 12/17/2008 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 74 Female 179 lb 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Eye Swelling Other Serious 8/6/2007 66 Male 179 lb 12/31/2008 Physician Austria
Primary
Secondary
Concomitant
Blood Glucose Increased 12/1/2008 68 Male 1/5/2009 Consumer
Primary
Concomitant
Memory Impairment Other Serious 9/1/2008 Male 166 lb 1/7/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 166 lb 1/6/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 1/20/2009 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Male 200 lb 1/21/2009 Physician United States
Primary
Secondary
Concomitant
Haematoma 12/9/2008 Female 2/17/2009 Consumer
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 6/20/2008 62 Male 2/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haematoma 12/9/2008 Female 2/24/2009 Consumer
Primary
Concomitant
Intermittent Claudication 9/1/2008 78 Male 171 lb 2/16/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization Male 3/6/2009 Physician United Kingdom
Primary
Concomitant
Lower Limb Fracture Other Serious 6/1/2006 38 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 3/10/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 71 Female 134 lb 3/17/2009 Lawyer United States
Primary
Secondary
Concomitant
Swelling Face 2/1/2009 83 Male 3/18/2009 Consumer
Primary
Concomitant
Heart Injury Other Serious 9/8/2006 58 Male 220 lb 3/20/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization Male 3/23/2009 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious 3/4/2009 69 Male 3/25/2009 Other Health Professional United States
Primary
Concomitant
Scar Other Serious 49 Female 150 lb 3/27/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 66 Male 3/27/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2008 Female 148 lb 4/6/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/1/2008 Female 4/3/2009 Consumer United States
Primary
Concomitant
Haematoma 12/9/2008 Female 4/16/2009 Consumer
Primary
Concomitant
Renal Failure Acute Life Threatening 3/12/2009 72 Female 155 lb 4/13/2009 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2006 58 Female 4/17/2009 Consumer United States
Primary
Concomitant
Feeling Abnormal 63 Male 180 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Hypertension Other Serious 3/4/2009 69 Male 4/16/2009 Other Health Professional United States
Primary
Concomitant

Drug Data