Metformin Hcl combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 9/1/2005 65 Female 1/12/2006 Switzerland
Primary
Secondary
Concomitant
Skin Graft Rejection Other Serious 9/15/2005 Male 192 lb 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 9/1/2005 65 Female 130 lb 1/17/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Disability 10/1/2005 64 Male 218 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/13/2006 Physician Sweden
Primary
Concomitant
Thirst Decreased Other Serious 97 Female 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Adverse Event Other Serious 8/3/2005 68 Female 1/25/2006 Physician Sweden
Primary
Concomitant
Joint Injury Other Serious Male 180 lb 1/20/2006 United States
Primary
Concomitant
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 66 Male 1/30/2006 Physician United States
Primary
Concomitant
Thirst Decreased Other Serious 97 Female 1/24/2006 United Kingdom
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Pulmonary Mass Other Serious 12/6/2005 59 Female 2/3/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Mental Impairment Other Serious 8/1/2003 42 Male 2/6/2006 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 9/1/2005 65 Female 2/7/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 2/10/2006 Physician Sweden
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/6/2005 59 Female 2/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thirst Decreased Other Serious 97 Female 2/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tremor Other Serious 1/14/2006 65 Female 2/2/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/14/2006 Physician South Africa
Primary
Concomitant
Myocardial Infarction Hospitalization 2/5/2006 Male 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 2/24/2006 Physician Sweden
Primary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/24/2006 Physician South Africa
Primary
Concomitant
Neutropenia Other Serious 2/22/2005 38 Male 245 lb 4/1/2005 Pharmacist United States
Primary
Concomitant
Headache Other Serious 2/10/2006 49 Female 170 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 2/10/2006 49 Female 170 lb 3/15/2006 United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 2/12/2006 71 Male 3/9/2006 Consumer United Kingdom
Primary
Concomitant
Polyneuropathy Hospitalization 5/20/2005 75 Female 3/28/2006 Physician Netherlands
Primary
Concomitant
Urticaria Hospitalization 2/8/2006 44 Male 247 lb 2/8/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 11/1/2003 Female 197 lb 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 51 Female 7/11/2006 United States
Primary
Secondary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 8/3/2006 76 Male 8/25/2006 Pharmacist United States
Primary
Concomitant
Oedema Life Threatening 6/16/2006 Male 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/14/2004 72 Male 170 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/22/2006 United Kingdom
Primary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/20/2006 70 Male 335 lb 9/7/2006 Consumer United States
Primary
Concomitant
Pulmonary Calcification Hospitalization 8/2/2006 Female 165 lb 9/11/2006 Other Health Professional Romania
Primary
Secondary
Concomitant
Hyperhidrosis 5/31/2006 62 Male 284 lb 7/19/2006 Consumer United States
Primary
Concomitant
Cough Other Serious 74 Female 9/7/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 7/19/2005 61 Female 151 lb 7/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2006 72 Male 280 lb 9/8/2006 Other Health Professional United States
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 9/4/2006 Male 9/18/2006 Pharmacist Canada
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Oedema Life Threatening 6/16/2006 Male 9/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death 6/16/2006 57 Male 179 lb 10/5/2006 Physician Germany
Primary
Concomitant
Rash Hospitalization 9/22/2006 77 Female 128 lb 10/5/2006 Physician Australia
Primary
Secondary
Concomitant
Oedema Life Threatening 6/16/2006 Male 9/29/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/18/2006 62 Male 10/5/2006
Primary
Secondary
Concomitant
Rash Hospitalization 9/22/2006 77 Male 128 lb 10/11/2006 Physician Australia
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 72 Male 174 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 1/1/2006 Male 240 lb 10/10/2006 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/28/2006 76 Male 200 lb 10/17/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 72 Male 280 lb 10/16/2006 United States
Primary
Concomitant
Somnolence Other Serious 73 Male 1766 lb 10/18/2006 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 9/22/2006 77 Male 128 lb 10/25/2006 Physician Australia
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2006 74 Male 10/19/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/28/2006 Female 196 lb 11/8/2006 Sweden
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/1/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Disability 7/1/2006 73 Female 11/3/2006 Pharmacist United Kingdom
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 11/7/2006 Physician Sweden
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/13/2006 United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/8/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination, Visual Disability 65 Female 11/14/2006 Physician New Zealand
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 7/18/2006 62 Male 12/5/2006
Primary
Secondary
Concomitant
Guillain-barre Syndrome Hospitalization 9/4/2006 Male 206 lb 12/5/2006 Pharmacist Canada
Primary
Concomitant
Pancreatitis Hospitalization 8/12/2006 59 Male 293 lb 12/6/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention Death 10/14/2006 69 Female 11/27/2006 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Other Serious 10/2/2006 70 Male 12/7/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/12/2006 59 Male 293 lb 12/7/2006 Physician United Kingdom
Primary
Concomitant
Pyrexia Life Threatening 11/10/2006 60 Female 212 lb 11/28/2006 Physician Australia
Primary
Secondary
Concomitant
Expired Drug Administered 72 Male 190 lb 12/1/2006 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 11/14/2006 69 Male 202 lb 12/1/2006 Consumer United States
Primary
Concomitant
Infusion Site Reaction Hospitalization 10/1/2006 70 Male 187 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 12/6/2006 Physician Spain
Primary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/1/2006 Male 240 lb 12/6/2006 United States
Primary
Concomitant
Swelling Life Threatening 6/16/2006 Male 12/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tendonitis Disability 1/1/2006 63 Female 165 lb 12/26/2006 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Other Serious 53 Male 12/19/2006 United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Somnolence Other Serious 11/16/2006 53 Female 12/27/2006 Pharmacist United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 12/19/2006 Male 245 lb 12/28/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 68 Male 12/15/2006 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 11/22/2006 67 Male 12/29/2006 Other Health Professional Sweden
Primary
Concomitant
Psychotic Disorder Hospitalization 12/16/2006 63 Male 183 lb 12/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 45 Male 1/3/2007 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2006 34 Male 359 lb 1/3/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Required Intervention 11/15/2006 74 Male 12/27/2006 United Kingdom
Primary
Concomitant
Middle Insomnia 7/12/2006 82 Male 200 lb 10/11/2006 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 1/1/2005 72 Male 174 lb 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Venous Thrombosis Hospitalization 1/28/2006 83 Male 192 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/9/2007 Consumer Brazil
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 8/14/2006 Female 199 lb 1/10/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 11/10/2006 60 Female 212 lb 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Hallucination Disability 69 Female 1/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/2/2006 1/12/2007 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/12/2007 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2005 43 Male 185 lb 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 1/1/2006 51 Male 1/11/2007 Sweden
Primary
Secondary
Concomitant
Rash Hospitalization 7/14/2006 63 Male 181 lb 10/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/23/2007 Consumer Brazil
Primary
Secondary
Concomitant
Oedema Life Threatening 6/16/2006 Male 1/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 7/17/2006 46 Male 258 lb 11/28/2006 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 10/19/2006 83 Male 175 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Epistaxis Other Serious 12/18/2006 88 Male 150 lb 12/21/2006 Pharmacist United States
Primary
Concomitant
Nightmare Other Serious 12/1/2006 Male 180 lb 1/26/2007 Consumer United States
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 1/1/2006 53 Female 191 lb 10/16/2006 Consumer United States
Primary
Concomitant
Blindness Other Serious 12/1/2006 Male 1/29/2007 Consumer United States
Primary
Concomitant
Weight Increased Death 5/1/2006 65 Male 1/25/2007 Germany
Primary
Concomitant
Gynaecomastia Other Serious 12/1/2006 Male 1/25/2007 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 10/1/2006 75 Female 1/29/2007 Pharmacist Netherlands
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 75 Male 1/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/3/2005 66 Male 2/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tension 4/15/2006 84 Male 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/17/2006 73 Male 135 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 12/27/2006 Male 165 lb 2/4/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 2/9/2007 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 75 Male 2/6/2007 United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 75 Male 2/13/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Cataract Subcapsular Disability 6/1/2004 Female 144 lb 2/15/2007 Singapore
Primary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 1/20/2006 43 Male 250 lb 2/12/2007 Consumer United States
Primary
Concomitant
Surgery Other Serious 2/5/2007 55 Female 2/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Schizophrenia, Paranoid Type Other Serious Male 2/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Overdose Death 1/25/2007 60 Male 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/2/2006 70 Male 243 lb 2/22/2007 Physician Denmark
Primary
Concomitant
Oedema Required Intervention 2/15/2007 79 Male 197 lb 2/21/2007 Physician United States
Primary
Concomitant
Renal Failure Other Serious 11/1/2005 Male 308 lb 2/12/2007 Physician United States
Primary
Concomitant
Weight Decreased 66 Male 2/27/2007 Other Health Professional United States
Primary
Concomitant

Drug Data