Simvastatin combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toxic Epidermal Necrolysis Life Threatening 1/14/2006 69 Male 2/21/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Portal Hypertensive Gastropathy Hospitalization 1/1/2006 62 Female 3/29/2006 Consumer Denmark
Primary
Concomitant
Lung Adenocarcinoma Stage I Required Intervention 11/17/2005 78 Male 198 lb 4/20/2006 Physician United States
Primary
Concomitant
Varicella Hospitalization 8/29/2000 62 Female 5/11/2006 Consumer Denmark
Primary
Concomitant
Tachycardia Hospitalization 8/24/2005 85 Male 5/12/2006 Other Health Professional Australia
Primary
Concomitant
Varicella Hospitalization 8/29/2000 62 Female 5/25/2006 Consumer Denmark
Primary
Concomitant
Sinus Headache Disability 5/4/2006 79 Male 212 lb 6/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2006 77 Female 6/22/2006 Other Health Professional Sweden
Primary
Concomitant
Interacting
Transaminases Increased Hospitalization 3/1/2006 77 Female 6/23/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/21/2006 82 Male 174 lb 7/6/2006 Physician United States
Primary
Concomitant
Feeling Abnormal 3/2/2006 82 Male 5/19/2006 United States
Primary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/20/2006 Physician United States
Primary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/28/2006 Physician United States
Primary
Concomitant
Drug Level Increased Hospitalization 7/28/2006 64 Female 8/21/2006 Consumer Netherlands
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/23/2006
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/30/2006
Primary
Secondary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Pleural Effusion Other Serious 7/20/2006 70 Male 335 lb 9/7/2006 Consumer United States
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2006 77 Female 9/20/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Cor Pulmonale Death Male 9/29/2006 Physician Germany
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Nasal Congestion 5/10/2006 Male 8/22/2006 United States
Primary
Concomitant
Drug Ineffective Hospitalization 82 Male 10/30/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 9/8/2006 64 Male 172 lb 11/20/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/8/2006 64 Male 172 lb 11/20/2006 Physician Spain
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/5/2006 82 Male 11/24/2006 Consumer United States
Primary
Concomitant
Tooth Discolouration Other Serious 6/1/2006 12/13/2006 Physician
Primary
Concomitant
Lip Swelling Other Serious 1/1/2007 Female 128 lb 1/11/2007 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 1/14/2007 87 Female 138 lb 1/19/2007 United States
Primary
Concomitant
Convulsion Hospitalization 11/24/2006 69 Male 1/19/2007 Pharmacist United Kingdom
Primary
Concomitant
Blood Creatine Increased Hospitalization 1/16/2007 74 Male 1/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Lip Swelling Other Serious 1/1/2007 Female 128 lb 1/22/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2003 Female 10/10/2006 Consumer United States
Primary
Concomitant
Feeling Abnormal 3/2/2006 82 Male 11/21/2006 United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 10/1/2006 82 Male 2/12/2007 Consumer United States
Primary
Concomitant
Throat Cancer Other Serious 12/1/2006 68 Male 3/12/2007 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 10/1/2006 75 Female 3/15/2007 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 3/27/2006 71 Male 165 lb 3/26/2007 Physician Germany
Primary
Secondary
Concomitant
Lip Swelling Other Serious 1/1/2007 Female 128 lb 3/27/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 10/1/2006 75 Female 4/20/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2007 78 Male 4/24/2007 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 4/1/2007 78 Male 5/3/2007 Physician Germany
Primary
Concomitant
Tooth Loss 7/1/2006 52 Male 2/22/2007 United States
Primary
Concomitant
Joint Swelling 12/27/2006 84 Male 145 lb 2/22/2007 United States
Primary
Concomitant
Pain 1/1/2006 Male 2/22/2007 United States
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2007 Male 364 lb 6/18/2007 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 3/20/2007 75 Male 141 lb 6/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/13/2007 64 Female 6/28/2007 Physician
Primary
Concomitant
Hypoglycaemia Other Serious 6/4/2007 61 Female 190 lb 7/3/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 65 Female 7/11/2007 Consumer United States
Primary
Concomitant
Troponin Increased Other Serious Male 159 lb 7/24/2007 Physician Australia
Primary
Concomitant
Weight Increased Hospitalization 65 Female 8/8/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 12/20/2006 Male 190 lb 8/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/16/2007 72 Male 8/31/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 9/4/2007 Consumer United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/4/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2007 74 Female 9/6/2007 Consumer United States
Primary
Concomitant
Tongue Disorder Hospitalization 4/26/2007 78 Male 375 lb 9/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/7/2007 Consumer United States
Primary
Secondary
Concomitant
Stress Other Serious 10/1/2006 Female 170 lb 9/13/2007 Consumer United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/18/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Female 276 lb 9/20/2007 Consumer United States
Primary
Concomitant
Overdose 6/13/2007 78 Male 7/26/2007 United States
Primary
Secondary
Concomitant
Stress Other Serious 10/1/2006 Female 170 lb 9/26/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/16/2007 72 Male 9/28/2007 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 72 Male 9/27/2007 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 6/6/2007 Male 10/2/2007 Physician
Primary
Concomitant
Macular Hole 6/21/2006 71 Female 10/12/2007 Consumer United States
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 10/1/2007 62 Female 174 lb 10/17/2007 Consumer United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Hospitalization 7/7/2007 Male 172 lb 10/15/2007 Consumer United States
Primary
Secondary
Concomitant
Oral Pain 71 Female 10/24/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/1/2007 82 Female 10/25/2007 Consumer United States
Primary
Concomitant
Dyspepsia 7/24/2007 61 Male 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Dry Eye 7/1/2007 69 Male 10/30/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 7/1/2007 54 Male 11/6/2007 Physician Czech Republic
Primary
Concomitant
Diabetic Neuropathy 75 Male 11/7/2007 Consumer United States
Primary
Concomitant
Dizziness Male 11/13/2007 Consumer United States
Primary
Concomitant
Total Lung Capacity Decreased Female 11/13/2007 Consumer United States
Primary
Concomitant
Tremor 75 Male 11/13/2007 Consumer United States
Primary
Concomitant
Confusional State Other Serious 9/1/2007 67 Female 121 lb 11/16/2007 Physician
Primary
Concomitant
Renal Failure Acute Other Serious 8/9/2007 Male 165 lb 11/20/2007 Physician Australia
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thirst 10/1/2007 Male 11/28/2007 Consumer United States
Primary
Concomitant
Overdose 6/13/2007 78 Male 10/22/2007 United States
Primary
Secondary
Concomitant
Blood Glucose Decreased 8/6/2007 Female 252 lb 11/29/2007 Consumer United States
Primary
Concomitant
Total Lung Capacity Decreased Female 11/29/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Tremor 10/1/2007 75 Male 12/3/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 8/1/2007 69 Male 12/5/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 7/11/2007 69 Male 12/14/2007 Consumer United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 11/16/2007 69 Female 12/17/2007 Physician Germany
Primary
Concomitant
Skin Laceration Hospitalization 12/23/2007 71 Male 160 lb 12/27/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea Exertional 11/1/2007 69 Female 1/2/2008 Consumer United States
Primary
Concomitant
Hepatitis Hospitalization 11/16/2007 74 Male 12/27/2007 Physician Germany
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Female 1/4/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 8/1/2007 69 Male 1/9/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization Female 1/16/2008 Consumer United States
Primary
Concomitant
Cough Male 1/28/2008 Consumer United States
Primary
Concomitant
Dermatitis Bullous Hospitalization 69 Male 2/8/2008 Physician
Primary
Concomitant
Ill-defined Disorder 6/1/2007 Female 2/12/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 10/1/2007 Female 2/14/2008 Consumer United States
Primary
Concomitant
Laboratory Test Abnormal 11/26/2007 88 Female 107 lb 11/26/2007 Other Health Professional United States
Primary
Concomitant
Dermatitis Bullous Other Serious 1/18/2008 Male 148 lb 2/22/2008 Physician France
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 10/1/2007 62 Female 170 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/24/2008 78 Female 108 lb 3/3/2008 Consumer United States
Primary
Concomitant
Thirst 10/1/2007 Male 3/5/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2007 Male 3/5/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 61 Female 170 lb 2/25/2008 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Exertional 11/1/2007 69 Female 3/10/2008 Consumer United States
Primary
Concomitant
Jaundice Other Serious 1/1/2008 70 Male 3/12/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/21/2008 52 Male 3/12/2008 Physician Germany
Primary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 61 Female 170 lb 2/25/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 71 Male 159 lb 3/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/10/2008 71 Male 159 lb 3/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cough Male 3/18/2008 Consumer United States
Primary
Concomitant
Jaundice Hospitalization 2/1/2008 Male 3/21/2008 Physician Germany
Primary
Secondary
Concomitant
Blood Glucose Fluctuation Other Serious 10/1/2007 62 Female 170 lb 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Rhinitis 1/1/2007 Male 4/11/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious Male 208 lb 4/14/2008 Physician Australia
Primary
Concomitant
Intraocular Pressure Increased 1/21/2008 Female 4/14/2008 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 1/1/2007 Male 4/16/2008 Consumer Brazil
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 52 Male 4/16/2008 Physician Germany
Primary
Concomitant
Urinary Retention 10/1/2007 63 Female 4/21/2008 Consumer United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 8/21/2007 Male 4/21/2008 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 67 Male 4/22/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2007 85 Male 4/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pemphigoid Other Serious 1/18/2008 Male 148 lb 4/30/2008 Physician France
Primary
Concomitant
Pollakiuria Disability 3/27/2008 72 Female 4/30/2008 Physician
Primary
Concomitant
Mental Status Changes Life Threatening 4/21/2008 80 Male 5/3/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 4/20/2008 Female 5/5/2008 Consumer United States
Primary
Concomitant
Dyspnoea Female 5/12/2008 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 67 Male 5/13/2008 Consumer United States
Primary
Concomitant
Urinary Retention 8/1/2007 62 Female 97 lb 5/16/2008 Physician United States
Primary
Concomitant
Lung Disorder 3/1/2008 75 Male 5/22/2008 Consumer United States
Primary
Concomitant
Pneumonia Life Threatening 1/1/2005 78 Male 241 lb 5/27/2008 Physician Canada
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/29/2008 77 Female 148 lb 5/22/2008 United States
Primary
Concomitant
Syncope Other Serious 80 Male 5/28/2008 Physician United States
Primary
Secondary
Concomitant
Dry Mouth Female 5/30/2008 Consumer United States
Primary
Concomitant
Dyspnoea Female 5/30/2008 Consumer United States
Primary
Concomitant
Lacrimation Increased 5/7/2008 Female 6/6/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 6/4/2008 72 Male 159 lb 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 5/12/2008 74 Male 6/11/2008 Consumer United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 2/29/2008 61 Male 4/30/2008 United States
Primary
Concomitant
Dry Mouth Female 7/1/2008 Consumer United States
Primary
Concomitant
Cough 4/1/2008 Female 7/1/2008 Consumer United States
Primary
Concomitant

Drug Data