Methylprednisolone combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastrointestinal Haemorrhage Hospitalization 12/2/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Renal Cyst Life Threatening 1/1/2002 74 Male 187 lb 3/13/2006 Physician Germany
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 4/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/21/2006 82 Male 174 lb 7/6/2006 Physician United States
Primary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/20/2006 Physician United States
Primary
Concomitant
Hyperhidrosis Required Intervention 7/11/2006 54 Male 165 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/2/2006 76 Male 7/19/2006 Physician Italy
Primary
Concomitant
Rhabdomyolysis Other Serious 34 Male 7/21/2006 Other Health Professional Spain
Primary
Concomitant
Wheezing Hospitalization 6/21/2006 82 Male 174 lb 7/28/2006 Physician United States
Primary
Concomitant
Tendon Rupture Disability 4/28/2006 68 Male 174 lb 9/8/2006 Physician Denmark
Primary
Secondary
Concomitant
Synovial Fluid Analysis Hospitalization 8/26/2006 Male 12/22/2006 Other Health Professional Belgium
Primary
Concomitant
Pneumonia Hospitalization 7/6/2006 68 Female 1/5/2007 Physician Germany
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2000 26 Male 310 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization Female 243 lb 7/18/2007 Physician Switzerland
Primary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 7/27/2007 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 7/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 7/1/2007 67 Male 8/8/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 6/4/2007 31 Female 139 lb 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 9/1/2007 54 Female 120 lb 9/20/2007 Consumer United States
Primary
Concomitant
Cardiac Valve Disease Hospitalization Female 9/26/2007 Belgium
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 9/18/2007 Physician Japan
Primary
Secondary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Infection Other Serious 9/17/2007 Female 159 lb 10/17/2007 Czech Republic
Primary
Concomitant
Sarcoidosis Life Threatening 7/1/2007 67 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 10/25/2007 Male 11/2/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 7/1/2007 69 Male 132 lb 11/2/2007 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 66 Male 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 11/19/2007 Female 183 lb 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 10/1/2006 Female 159 lb 12/13/2007 Czech Republic
Primary
Concomitant
Myopathy Toxic Death 66 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 66 Male 1/8/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 1/25/2008 63 Female 2/12/2008 Physician Italy
Primary
Concomitant
Knee Arthroplasty Hospitalization 10/19/2006 Female 2/15/2008 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 66 Male 2/19/2008 United States
Primary
Concomitant
Rhabdomyolysis Death 66 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious Female 3/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 3/20/2008 Male 183 lb 4/4/2008 Physician Poland
Primary
Concomitant
Posturing Life Threatening 6/21/2007 68 Male 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2007 Male 4/22/2008 Czech Republic
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 5/19/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 1/25/2008 63 Female 5/29/2008 Physician Italy
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 6/13/2008 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 4/23/2008 Female 6/24/2008 Belgium
Primary
Concomitant
Weight Decreased Other Serious 66 Male 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 8/8/2007 Female 6/27/2008 Belgium
Primary
Concomitant
Myocardial Infarction Death 57 Female 131 lb 6/30/2008 Austria
Primary
Concomitant
Hallucination, Visual Hospitalization 9/6/2007 94 Female 193 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 10/1/2008 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 10/2/2008 82 Female 12/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Toxic Death 10/2/2008 82 Female 167 lb 12/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 10/14/2008 75 Female 135 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 11/1/2006 Male 269 lb 5/18/2009 Consumer United States
Primary
Concomitant
Dizziness Other Serious 4/11/2009 Female 5/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Tremor Other Serious 5/1/2006 58 Female 6/12/2009 Other Health Professional Finland
Primary
Concomitant
Interacting
Renal Impairment Other Serious 9/2/2005 Male 269 lb 6/17/2009 Physician United States
Primary
Concomitant
Wound Infection Other Serious 6/12/2003 Male 141 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Urosepsis Hospitalization 11/19/2003 Female 123 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2003 Male 154 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 5/24/2006 Male 165 lb 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Urosepsis Life Threatening 9/6/2004 Male 159 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/12/2003 Female 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 11/26/2003 Female 133 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/26/2004 Female 101 lb 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 3/20/2005 Male 6/24/2009 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Life Threatening 10/8/2003 Female 6/25/2009 Physician Brazil
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4/2/2009 39 Female 110 lb 4/28/2009 Pharmacist United States
Primary
Concomitant
Microcytic Anaemia Hospitalization Female 7/9/2009 Physician Belgium
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/5/2009 71 Female 175 lb 7/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Renal Failure Other Serious 3/6/2009 Female 84 lb 7/29/2009 Germany
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 4/1/2007 56 Male 8/10/2009 Other Health Professional Spain
Primary
Secondary
Interacting
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Sinusitis 12/1/2007 Female 138 lb 9/12/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Renal Impairment Other Serious 9/2/2005 Male 269 lb 10/2/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 56 Male 10/12/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/7/2009 74 Male 11/25/2009 Physician Portugal
Primary
Concomitant
Pancreatic Necrosis Hospitalization 12/1/2008 63 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Haematuria Hospitalization 6/16/2008 Female 185 lb 12/7/2009 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 12/14/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 66 Male 1/6/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 66 Male 1/6/2010 United States
Primary
Secondary
Concomitant
Interacting
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 1/18/2010 Physician United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Transplant Other Serious 3/6/2009 29 Female 79 lb 1/29/2010 Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 30 Female 2/18/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 30 Female 2/19/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 2/26/2010 Physician Hungary
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 3/10/2010 Physician Hungary
Primary
Concomitant
Muscular Weakness Hospitalization 2/21/2010 Male 187 lb 3/15/2010 Physician Spain
Primary
Concomitant
Renal Disorder Other Serious 1/8/2010 66 Female 116 lb 1/10/2010 Pharmacist United States
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 Female 119 lb 3/31/2010 Physician Hungary
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 3/31/2010 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/21/2010 58 Male 187 lb 4/13/2010 Physician Spain
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 4/16/2010 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/21/2010 58 Male 187 lb 4/22/2010 Physician Spain
Primary
Concomitant
Von Willebrand's Factor Antigen Increased Other Serious 12/23/2009 56 Female 119 lb 4/27/2010 Physician Hungary
Primary
Concomitant
Pneumonia Hospitalization 11/20/2009 55 Female 152 lb 4/28/2010 Physician Philippines
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/20/2009 55 Female 152 lb 5/3/2010 Physician Philippines
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2009 68 Female 146 lb 5/17/2010 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 6/9/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 7/7/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 12/9/2008 51 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 1/28/2010 66 Male 249 lb 7/9/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 8/2/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 8/23/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 12/19/2007 68 Male 179 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 63 Male 274 lb 9/2/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/17/2006 46 Male 260 lb 9/20/2010 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 12/19/2007 58 Male 179 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 78 Female 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/1/2006 58 Female 10/12/2010 Other Health Professional Finland
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 3/1/2008 78 Female 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Life Threatening 1/1/2010 66 Male 10/21/2010 Other Health Professional France
Primary
Secondary
Concomitant
Trigeminal Neuralgia Other Serious 10/1/2009 68 Female 146 lb 11/2/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/26/2010 11/2/2010 Physician Germany
Primary
Concomitant
Muscular Weakness Hospitalization 2/21/2010 11/2/2010 Physician Spain
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 2/1/2008 76 Female 135 lb 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 12/19/2007 58 Male 179 lb 11/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 12/9/2010 Physician Belgium
Primary
Concomitant
Muscular Weakness Other Serious 2/21/2010 12/14/2010 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Other Serious Female 12/14/2010 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/2004 47 Male 12/22/2010 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 1/1/2008 69 Female 165 lb 2/22/2011 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 3/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 4/6/2010 65 Male 201 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data