Simvastatin combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Movement Disorder Hospitalization 1/1/2005 40 Male 1/3/2006 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 1/5/2006 67 Male 191 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Disability 5/8/2006 67 Male 9/12/2006 Norway
Primary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 1/10/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 1/22/2007 Physician Germany
Primary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/5/2006 Male 191 lb 3/5/2007 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 57 Male 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Disability 5/8/2006 67 Male 3/1/2007 Physician Norway
Primary
Concomitant
Nephritis Interstitial Other Serious 4/29/2005 Female 208 lb 3/23/2007 Physician Brazil
Primary
Concomitant
Renal Failure Acute Life Threatening 2/22/2007 Female 388 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/7/2007 Male 170 lb 3/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/22/2007 Female 388 lb 3/30/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/22/2007 Female 176 lb 4/4/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/19/2006 Male 163 lb 4/23/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/10/2007 Male 5/25/2007 Physician United States
Primary
Concomitant
Death Death 6/19/2006 Male 163 lb 6/4/2007 United States
Primary
Concomitant
Death Death 6/19/2006 Male 163 lb 6/25/2007 United States
Primary
Concomitant
Melaena Other Serious 4/10/2007 42 Male 7/10/2007 United Kingdom
Primary
Secondary
Concomitant
Death Death 6/19/2006 Male 163 lb 7/17/2007 United States
Primary
Concomitant
Melaena Other Serious 4/10/2007 42 Male 7/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Meningioma Other Serious 4/12/2006 Male 170 lb 8/7/2007 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Throat Tightness 11/1/2007 62 Male 328 lb 2/16/2008 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2005 31 Male 4/30/2008 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 4/12/2006 Male 170 lb 5/29/2008 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2005 31 Male 6/3/2008 Consumer United States
Primary
Concomitant
Urine Output Increased Other Serious 12/21/2007 Female 170 lb 7/16/2008 Physician Germany
Primary
Concomitant
Cardiac Failure Life Threatening 8/3/2008 63 Male 8/8/2008 Sweden
Primary
Concomitant
Presyncope Other Serious 6/1/2008 63 Male 131 lb 8/11/2008 Sweden
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1989 59 Male 156 lb 8/15/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urine Output Increased Other Serious 12/21/2007 Female 170 lb 8/22/2008 Physician Germany
Primary
Concomitant
Large Intestine Perforation Hospitalization Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 8/27/2008 Sweden
Primary
Concomitant
Weight Decreased Other Serious 1/1/1989 59 Male 156 lb 9/5/2008 United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 133 lb 9/9/2008 Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/3/2008 59 Male 156 lb 9/10/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2006 Female 11/21/2008 Other Health Professional Italy
Primary
Concomitant
Diarrhoea Male 280 lb 11/26/2008 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/12/2006 Female 12/1/2008 Other Health Professional Italy
Primary
Concomitant
Renal Cancer Other Serious Male 12/4/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/16/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/18/2008 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 10/1/2007 Male 12/22/2008 Other Health Professional Norway
Primary
Concomitant
Interacting
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/26/2008 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 10/1/2007 Male 1/15/2009 Other Health Professional Norway
Primary
Concomitant
Interacting
Blood Pressure Increased 5/1/2007 56 Male 216 lb 1/13/2009 Consumer United States
Primary
Concomitant
Renal Cancer Other Serious Male 1/20/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/31/2007 Male 1/30/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/31/2007 Male 2/9/2009 Pharmacist United States
Primary
Concomitant
Urosepsis Hospitalization 10/14/2008 75 Female 135 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Troponin Increased Hospitalization 1/29/2009 74 Male 3/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/12/2006 Female 4/9/2009 Other Health Professional Italy
Primary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/11/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 9/22/2008 74 Male 276 lb 5/29/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 44 Female 6/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic 3/27/2009 Male 6/30/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Rash Pruritic 1/1/2006 Male 150 lb 7/23/2009 Consumer United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 10/1/2007 63 Female 1/11/2010 Lawyer United States
Primary
Concomitant
Hypokalaemia Life Threatening 44 Female 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Hypokalaemia Life Threatening 44 Female 2/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Respiratory Arrest Other Serious 1/29/2008 38 Male 2/17/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 65 Female 3/25/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Death 10/1/2007 Male 3/31/2010 Other Health Professional Norway
Primary
Concomitant
Interacting
Ventricular Tachycardia Life Threatening 10/22/2007 63 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Conjunctival Haemorrhage Other Serious 1/25/2010 63 Male 4/23/2010 Other Health Professional United States
Primary
Concomitant
Conjunctival Haemorrhage Other Serious 1/25/2010 63 Male 4/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 5/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 1/25/2008 38 Male 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 73 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Blood Calcium Increased 5/28/2009 68 Female 5/26/2010 United States
Primary
Concomitant
Headache 3/27/2010 70 Male 5/26/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Death 10/1/2007 55 Male 6/14/2010 Other Health Professional Norway
Primary
Concomitant
Interacting
Wheelchair User Disability 5/8/2006 67 Male 6/11/2010 Norway
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2010 6/29/2010 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/10/2010 67 Male 155 lb 6/25/2010 United Kingdom
Primary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/6/2010 55 Male 205 lb 7/16/2010 Physician Italy
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Other Serious 1/25/2008 38 Male 260 lb 7/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 56 Male 7/27/2010 Lawyer United States
Primary
Concomitant
Pneumonitis Hospitalization 7/21/2010 68 Male 239 lb 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 8/26/2010 Other Health Professional United States
Primary
Concomitant
Urinary Casts Other Serious 8/3/2010 73 Female 124 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Parotitis Other Serious 4/19/2010 74 Female 8/20/2010 United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 9/22/2008 74 Male 276 lb 9/8/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 6/30/2010 74 Female 9/23/2010 Physician France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 6/30/2010 74 Female 9/24/2010 Consumer France
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 190 lb 9/24/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Death 1/1/2008 56 Male 123 lb 9/27/2010 Lawyer United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 10/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 64 Female 11/2/2010 United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Death 11/1/2010 67 Female 11/25/2010 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 10/3/2010 90 Female 12/3/2010 Physician Italy
Primary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 10/3/2010 90 Female 12/30/2010 Physician Italy
Primary
Concomitant
Abdominal Pain Death 1/25/2008 38 Male 260 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Angiogram Other Serious 5/1/2010 1/13/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 2/7/2011 60 Female 128 lb 2/16/2011 Physician Romania
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 2/7/2011 60 Female 128 lb 2/18/2011 Physician Romania
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 1/4/2011 72 Male 2/22/2011 Other Health Professional Sweden
Primary
Concomitant
Interacting
Drug Therapeutic Incompatibility Hospitalization 1/4/2011 72 Male 2/24/2011 Other Health Professional Sweden
Primary
Concomitant
Interacting
Renal Failure Other Serious 1/1/2011 74 Female 2/23/2011 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 11/18/2010 82 Female 158 lb 3/1/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Hospitalization 60 Male 2/24/2011 United States
Primary
Concomitant
Metastatic Malignant Melanoma Other Serious 11/18/2010 82 Female 158 lb 3/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 2/7/2011 60 Female 128 lb 3/10/2011 Physician Romania
Primary
Secondary
Concomitant
Drug Effect Decreased 9/1/2010 65 Male 230 lb 4/5/2011 Consumer United States
Primary
Concomitant

Drug Data