Fluconazole combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypercalcaemia 12/19/2005 65 Male 1/16/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 76 Male 1/10/2006 France
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Tremor Hospitalization 12/14/2005 86 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Palpable Purpura Hospitalization 1/25/2006 66 Male 161 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/19/2006 57 Female 245 lb 1/20/2006 United States
Primary
Secondary
Prothrombin Time Shortened Hospitalization 1/1/2006 85 Male 4/20/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 4/26/2006 70 Female 6/1/2006 Physician France
Primary
Concomitant
Splenomegaly Death 7/1/2006 36 Female 7/28/2006 Physician Philippines
Primary
Concomitant
Splenomegaly Other Serious 7/1/2006 36 Female 8/3/2006 Physician Philippines
Primary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 1/10/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 2/26/2003 Male 230 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Interacting
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/8/2007 68 Male 203 lb 2/28/2007 United Kingdom
Primary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vitamin K Deficiency Hospitalization 4/12/2007 68 Male 4/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 81 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 81 Male 6/15/2007 United Kingdom
Primary
Secondary
Concomitant
No Adverse Effect 81 Male 6/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 81 Male 6/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 81 Male 6/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 81 Male 6/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 1/1/2006 33 Female 230 lb 9/18/2007 Physician United States
Primary
Concomitant
Azotaemia Life Threatening 8/1/2007 Male 10/25/2007 Denmark
Primary
Concomitant
Rhabdomyolysis Required Intervention 10/12/2007 64 Male 11/16/2007 Pharmacist United States
Primary
Secondary
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oral Candidiasis 1/1/2004 76 Female 12/28/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/19/2007 65 Female 12/27/2007 Physician United Kingdom
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2008 74 Female 1/22/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2006 59 Male 225 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/5/2008 Physician United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/28/2008 Physician United Kingdom
Primary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 3/1/2007 Female 187 lb 4/17/2008 Denmark
Primary
Concomitant
Renal Pain Hospitalization Female 4/17/2008 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 79 Male 5/21/2008 United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious Male 5/29/2008 United States
Primary
Interacting
Speech Disorder Life Threatening 79 Male 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 6/17/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 79 Male 6/18/2008 United States
Primary
Concomitant
Interacting
Vomiting Other Serious 79 Male 6/26/2008 United Kingdom
Primary
Concomitant
Interacting
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Vomiting Other Serious 79 Male 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
No Adverse Event 79 Male 7/2/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 79 Male 7/2/2008 United Kingdom
Primary
Concomitant
Interacting
Skin Disorder Life Threatening 1/1/2008 Female 292 lb 6/29/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 79 Male 7/9/2008 United Kingdom
Primary
Concomitant
Interacting
Speech Disorder Hospitalization 79 Male 7/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vomiting Other Serious 79 Male 7/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 7/10/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 79 Male 7/8/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 79 Male 7/18/2008
Primary
Secondary
Concomitant
Skin Disorder Life Threatening 1/1/2008 Female 292 lb 7/14/2008 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 79 Male 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 79 Male 8/7/2008 United Kingdom
Primary
Concomitant
Interacting
Vomiting Life Threatening 79 Male 8/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 7/17/2008 74 Female 123 lb 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Life Threatening 79 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 8/28/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2003 45 Female 200 lb 9/5/2008 Consumer United States
Primary
Concomitant
No Adverse Event 79 Male 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 79 Male 9/12/2008 United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 79 Male 9/11/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 65 Female 10/15/2008 Other Health Professional Switzerland
Primary
Secondary
Rhabdomyolysis Other Serious 65 Female 10/21/2008 Other Health Professional Switzerland
Primary
Secondary
Rhabdomyolysis Other Serious 65 Female 10/20/2008 Switzerland
Primary
Interacting
Rhabdomyolysis Other Serious 65 Female 10/17/2008 Physician Switzerland
Primary
Secondary
Rhabdomyolysis Other Serious 65 Female 10/27/2008 Switzerland
Primary
Secondary
Rhabdomyolysis Hospitalization 1/1/2008 65 Female 10/21/2008 Physician Switzerland
Primary
Secondary
Rhabdomyolysis Hospitalization 65 Female 11/5/2008 Physician Switzerland
Primary
Secondary
Red Blood Cell Sedimentation Rate Increased Hospitalization 65 Female 11/10/2008 Physician Switzerland
Primary
Concomitant
Rhabdomyolysis Other Serious 65 Female 12/17/2008
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 65 Female 12/9/2008 Switzerland
Primary
Secondary
Rhabdomyolysis Other Serious 65 Female 12/30/2008 Physician Switzerland
Primary
Secondary
Rhabdomyolysis Other Serious 43 Male 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 43 Male 2/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 43 Male 2/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 43 Male 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 43 Male 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 43 Male 2/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 43 Male 2/3/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 65 Female 2/3/2009 Physician Switzerland
Primary
Secondary
Weight Decreased Hospitalization 43 Male 2/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/11/2009 United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 43 Male 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 12/1/2008 Female 216 lb 2/27/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 2/11/2009 72 Male 2/27/2009 Physician Thailand
Primary
Concomitant
Leukoencephalopathy Death Female 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 3/4/2009
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 43 Male 3/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 43 Male 2/26/2009 United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 43 Male 3/13/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Leukoencephalopathy Other Serious 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 43 Male 3/12/2009
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/9/2009 88 Male 181 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 2/11/2009 72 Male 3/23/2009 Physician Thailand
Primary
Concomitant
Leukoencephalopathy Death 1/1/2008 64 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation 3/26/1909 Female 152 lb 3/26/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 43 Male 3/27/2009 Physician United Kingdom
Primary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Leukoencephalopathy Other Serious 4/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Retinal Haemorrhage Other Serious 1/1/1997 Female 4/8/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 35 Female 250 lb 4/17/2009 Consumer United States
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Other Serious 79 Male 5/5/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data