Metoprolol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/28/2005 61 Female 187 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Angioneurotic Oedema Hospitalization 10/11/2005 80 Male 10/27/2005 Pharmacist United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/28/2005 61 Female 187 lb 1/12/2006 Denmark
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Renal Failure Chronic Required Intervention 11/9/2005 79 Female 1/16/2006 Physician United States
Primary
Concomitant
Retroperitoneal Haematoma Life Threatening 2/16/2004 66 Male 1/19/2006 Consumer Poland
Primary
Concomitant
Haemothorax Life Threatening 8/17/2004 77 Male 1/20/2006 Consumer Poland
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 12/11/2005 67 Male 1/18/2006 China
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 8/10/2004 50 Male 1/25/2006 Physician Brazil
Primary
Concomitant
Puncture Site Haemorrhage Hospitalization 10/14/2003 79 Male 1/25/2006 Consumer Italy
Primary
Concomitant
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Rhabdomyolysis Hospitalization 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Haematocrit Decreased Hospitalization 12/28/2005 62 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/13/2005 68 Male Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 10/11/2005 70 Male Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 8/19/2005 65 Male 212 lb 2/7/2006 Denmark
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 1/16/2006 77 Female 132 lb 2/7/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 2/10/2006 Poland
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Palpable Purpura Hospitalization 1/25/2006 66 Male 161 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Scintillating Scotoma 1/7/2006 57 Male 2/6/2006 Physician Germany
Primary
Concomitant
Nosocomial Infection Other Serious 10/6/2003 Male 240 lb 2/20/2006 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 89 Male 2/21/2006 Physician United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 4/27/2005 58 Male 201 lb 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 11/17/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Troponin Increased Hospitalization 11/13/2005 73 Male 134 lb 12/13/2005 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/6/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/3/2005 82 Female 176 lb 2/9/2006 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 57 Male 225 lb 3/6/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 7/19/2005 Male 271 lb 3/6/2006 Physician New Zealand
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/4/2005 75 Male 161 lb 3/2/2006 Other Health Professional Japan
Primary
Concomitant
Catheter Related Complication Other Serious 9/9/2003 77 Male 172 lb 3/14/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/17/2003 48 Male 238 lb 3/14/2006 Consumer Australia
Primary
Concomitant
Catheter Related Complication Life Threatening 1/19/2004 66 Female 172 lb 3/14/2006 Consumer Poland
Primary
Concomitant
Retinal Artery Embolism Other Serious 8/5/2004 48 Male 187 lb 3/14/2006 Consumer Poland
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/22/2006 79 Male 3/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 11/1/2004 61 Female 12/21/2005 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/14/2005 83 Male 210 lb 12/21/2005 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Dystonia 2/20/2006 54 Male 3/14/2006 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/15/2005 62 Male 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Somnolence Hospitalization 12/30/2004 80 Male 170 lb 3/30/2006 Pharmacist United States
Primary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Osteomyelitis Chronic Hospitalization 3/20/2006 59 Male 4/5/2006 Other Health Professional Brazil
Primary
Concomitant
Mucosal Inflammation Hospitalization 12/5/2005 61 Female 4/3/2006 Physician Netherlands
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/9/2005 65 Male 137 lb 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 1/22/2005 76 Male 185 lb 4/6/2006 Czech Republic
Primary
Secondary
Concomitant
Hallucination Required Intervention 4/9/2006 79 Male 191 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 3/5/2006 Male 4/3/2006 Pharmacist United States
Primary
Concomitant
Osteomyelitis Chronic Hospitalization 3/20/2006 59 Male 4/27/2006 Other Health Professional Brazil
Primary
Concomitant
Blood Glucose Decreased Hospitalization 4/14/2006 85 Male 194 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 4/25/2006 Poland
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/30/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 3/7/2006 57 Male 320 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 2/2/2006 64 Male 174 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 74 Male 211 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 3/21/2006 81 Male 203 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 62 Male 223 lb 4/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemic Coma Life Threatening 4/6/2006 61 Male 213 lb 6/2/2006 Other Health Professional Puerto Rico
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/19/2006 Male 148 lb 6/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 11/8/2005 71 Male 143 lb 7/18/2006 Physician Poland
Primary
Secondary
Concomitant
Nausea Other Serious 5/11/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Required Intervention 5/23/2006 71 Male 173 lb 6/7/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/27/2006 72 Male 177 lb 5/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 7/21/2006 Poland
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 7/14/2006 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 8/1/2005 73 Male 7/25/2006 Canada
Primary
Concomitant
Rash Pruritic 4/10/2006 67 Male 238 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/7/2006 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 10/24/2005 55 Female 220 lb 8/7/2006 Other Health Professional Netherlands
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 8/8/2006 Denmark
Primary
Concomitant
Haematemesis Other Serious 2/22/2006 79 Male 8/8/2006 Denmark
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 6/9/2006 75 Male 251 lb 8/17/2006 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 7/25/2006 52 Male 198 lb 8/29/2006 Romania
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 8/20/2006 85 Male 141 lb 9/8/2006 United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/22/2006 68 Male 9/11/2006 Physician Germany
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Post Procedural Complication Hospitalization 2/28/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Cough Other Serious 3/17/2006 83 Male 144 lb 3/17/2006 Pharmacist United States
Primary
Concomitant
Haematuria Hospitalization 7/18/2006 67 Male 9/14/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 4/19/2006 79 Male 148 lb 9/18/2006 United Kingdom
Primary
Secondary
Concomitant
Occult Blood Positive Required Intervention 1/14/2006 74 Female 109 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 56 Male 9/25/2006 Consumer United States
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Delirium Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 5/23/2006 73 Male 176 lb 9/13/2006 Netherlands
Primary
Secondary
Concomitant
Vessel Puncture Site Haematoma Hospitalization 5/8/2006 65 Female 154 lb 10/10/2006 Poland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 4/19/2006 79 Male 148 lb 10/9/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/20/2006 85 Male 141 lb 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Skin Necrosis Hospitalization 5/17/2006 50 Female 176 lb 10/11/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/28/2006 76 Male 200 lb 10/17/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 10/8/2006 70 Male 184 lb 10/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 56 Male 134 lb 10/25/2006 Consumer United States
Primary
Concomitant
Renal Failure Required Intervention 5/1/2005 63 Male 132 lb 9/25/2006 Physician United States
Primary
Concomitant
Wound Necrosis Hospitalization 5/17/2006 50 Female 176 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1/9/2007 59 Male 229 lb 1/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 65 Female 190 lb 2/12/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/19/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/21/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 5/14/2007 Physician Poland
Primary
Concomitant
Syncope Other Serious 1/1/2005 65 Female 190 lb 5/16/2007 Physician Poland
Primary
Concomitant
Candida Sepsis Other Serious 2/6/2006 69 Male 245 lb 7/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/26/2007 Female 132 lb 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/11/2000 68 Male 190 lb 9/25/2007 Consumer United States
Primary
Secondary
Concomitant
Overdose 6/13/2007 78 Male 7/26/2007 United States
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Other Serious 47 Female 10/1/2007 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 Male 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/1/2007 83 Female 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Faeces Discoloured Other Serious Male 10/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 5/31/2007 65 Male 9/27/2007 Other Health Professional Netherlands
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2007 Female 219 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Middle Insomnia 7/1/2007 72 Male 210 lb 10/5/2007 Consumer United States
Primary
Concomitant
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Headache 3/8/2007 80 Female 10/24/2007 Consumer United States
Primary
Concomitant
Cough 8/1/2007 83 Male 10/24/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 65 Male 10/24/2007 Consumer United States
Primary
Concomitant
Onychoclasis 4/1/2007 84 Male 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 8/1/2007 Male 220 lb 10/25/2007 Consumer United States
Primary
Concomitant
Reticulocyte Count Decreased Other Serious 5/3/2007 Male 190 lb 10/29/2007 Physician Germany
Primary
Concomitant
Wound Debridement Hospitalization 6/14/2006 56 Male 10/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Cessation Other Serious 1/1/2007 Male 160 lb 10/30/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/8/2007 75 Male 10/30/2007 Physician Netherlands
Primary
Concomitant
Constipation Other Serious 1/1/2005 Female 155 lb 11/1/2007 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2007 73 Female 11/6/2007 Consumer Italy
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 7/21/2007 Male 159 lb 11/8/2007 United States
Primary
Concomitant
Thrombosis Hospitalization 7/10/2007 60 Female 11/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/14/2004 46 Male 188 lb 11/20/2007 Physician Germany
Primary
Secondary
Concomitant

Drug Data