Simvastatin combined with Vitamin B12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hirsutism Female 12/7/2005 Pharmacist United States
Primary
Concomitant
Thyroxine Increased Other Serious 6/22/2005 77 Male 179 lb 11/16/2006 Other Health Professional United States
Primary
Concomitant
Stent Placement Life Threatening 6/18/2006 60 Male 202 lb 1/19/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/1/2007 94 Male 6/12/2007 Physician United States
Primary
Concomitant
Pain Hospitalization 6/1/2007 94 Male 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Sinusitis 8/1/2007 64 Female 219 lb 4/10/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 9/7/2008 34 Male 236 lb 10/6/2008 United States
Primary
Concomitant
Product Quality Issue Hospitalization 11/17/2008 78 Female 122 lb 12/15/2008 Consumer United States
Primary
Concomitant
Atrioventricular Block First Degree Other Serious 1/16/2009 Male 245 lb 2/2/2009 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/21/2009 52 Male 2/4/2009 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 9/7/2008 34 Male 236 lb 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/26/2009 72 Female 156 lb 9/15/2009 Other Health Professional United States
Primary
Concomitant
Walking Aid User Hospitalization 1/21/2009 52 Male 9/24/2009 United States
Primary
Concomitant
Viral Infection Other Serious 8/26/2009 72 Female 156 lb 10/14/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/1/2009 46 Male 176 lb 12/22/2009 United States
Primary
Concomitant
Weight Increased 73 Male 2/23/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 4/12/2009 67 Male 3/26/2010 Physician Germany
Primary
Secondary
Concomitant
Peripheral Embolism Other Serious 8/12/2007 77 Male 7/16/2010 Lawyer United States
Primary
Concomitant
Shock Hospitalization 8/6/2010 64 Male 142 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Other Serious 8/1/2007 77 Male 9/8/2010 Lawyer United States
Primary
Concomitant
Shock Hospitalization 8/6/2010 64 Male 142 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 10/11/2010 73 Male 204 lb 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/3/2010 69 Male 211 lb 12/27/2010 Physician United States
Primary
Concomitant
Neutropenic Colitis Hospitalization 3/4/2010 69 Male 211 lb 2/25/2011 Physician United States
Primary
Concomitant
Anaemia Hospitalization 3/4/2010 69 Male 211 lb 3/1/2011 Physician United States
Primary
Concomitant
Sudden Death Other Serious 8/29/2010 59 Male 143 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Angina Unstable Life Threatening 8/29/2010 59 Male 143 lb 3/30/2011 Physician United States
Primary
Concomitant
Interacting
Sudden Death Hospitalization 8/29/2010 59 Male 143 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Neutropenia Hospitalization 3/4/2010 69 Male 211 lb 4/6/2011 United States
Primary
Concomitant
Neutropenic Colitis Hospitalization 3/4/2010 69 Male 211 lb 4/15/2011 Physician United States
Primary
Concomitant
Cardiac Disorder Other Serious 11/1/2009 81 Female 11/3/2010 Physician United States
Primary
Concomitant
Tendonitis Other Serious 1/1/2010 62 Female 205 lb 6/16/2011 Other Health Professional United States
Primary
Concomitant
Tendonitis Other Serious 1/1/2010 62 Female 205 lb 6/27/2011 United States
Primary
Concomitant
Pruritus Hospitalization 1/1/2011 66 Male 220 lb 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Affective Disorder Hospitalization 6/1/2011 79 Male 272 lb 8/26/2011 Physician United States
Primary
Concomitant
Asthenia Hospitalization 3/15/2011 71 Male 185 lb 9/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Disability 8/29/2010 59 Male 143 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Muscle Twitching 8/17/2011 86 Male 161 lb 9/28/2011 Consumer United States
Primary
Concomitant
Retching Other Serious 8/28/2011 62 Female 180 lb 11/9/2011 Physician United States
Primary
Concomitant
Dyspnoea Life Threatening 8/28/2011 62 Female 180 lb 11/11/2011 Physician United States
Primary
Concomitant
Tachycardia Other Serious 49 Male 11/28/2011 Physician Netherlands
Primary
Secondary
Concomitant
Hypoaesthesia 7/15/2011 50 Female 200 lb 9/8/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 11/1/2007 53 Male 170 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 1/19/2011 42 Female 204 lb 12/5/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Female 4/7/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/1/2010 42 Female 190 lb 8/18/2011 Physician United States
Primary
Concomitant
Injection Site Mass Other Serious 6/1/2010 42 Female 8/19/2010 Other Health Professional United States
Primary
Concomitant
Chest Discomfort Hospitalization 3/11/2012 60 Female 108 lb 3/22/2012 Pharmacist United States
Primary
Concomitant
Bradycardia Hospitalization 1/17/2011 55 Female 3/24/2011 Physician United States
Primary
Concomitant
Tremor Other Serious 3/22/2011 58 Female 134 lb 6/24/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 5/16/2011 73 Male 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Myalgia 1/19/2011 42 Female 204 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2000 84 Male 220 lb 5/16/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 85 Male 5/16/2011 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2011 75 Male 167 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Food Poisoning Hospitalization 1/1/2011 70 Male 196 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Strongyloidiasis Hospitalization 1/1/2011 68 Male 185 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2011 59 Male 2/18/2011 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 1/21/2011 72 Female 5/16/2011 Physician United States
Primary
Concomitant
Rash Hospitalization 5/1/2011 69 Female 9/9/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/25/2011 47 Male 160 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 4/1/2011 72 Male 196 lb 6/1/2012 Physician United States
Primary
Concomitant
Fatigue Other Serious 67 Female 108 lb 12/15/2011 Physician United States
Primary
Concomitant
Oral Mucosal Blistering Other Serious 10/1/2011 77 Female 11/1/2011 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 8/15/2011 83 Male 165 lb 8/23/2011 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 9/8/2011 77 Female 196 lb 1/12/2012 Physician United States
Primary
Concomitant
Irritability Other Serious 87 Male 6/23/2012 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 77 Female 5/9/2011 Consumer United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 9/22/2011 37 Female 91 lb 7/26/2012 Physician Japan
Primary
Concomitant
Intestinal Obstruction Other Serious 1/5/2012 81 Female 8/1/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 83 Male 238 lb 1/29/2010 Physician United States
Primary
Concomitant
Intestinal Obstruction Other Serious 1/5/2012 81 Female 8/7/2012 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 5/16/2011 73 Male 8/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Vasogenic Cerebral Oedema Other Serious 3/23/2010 59 Male 220 lb 11/12/2012 Physician Us
Primary
Concomitant
Vomiting Other Serious 2009 Male 230 lb 1/8/2013 Physician Country Not Specified
Primary
Concomitant
Pulmonary Haemorrhage Death 2/9/2011 66 Male 3/18/2013 Physician Be
Primary
Secondary
Concomitant
Nausea Other Serious 11/11/2011 66 Female 196 lb 3/11/2013 Other Health Professional Ca
Primary
Concomitant
Skin Exfoliation Other Serious 2011 Female 125 lb 3/25/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 5/16/2011 73 Male 8/23/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/28/2012 86 Female 115 lb 10/17/2012 Physician Us
Primary
Secondary
Concomitant
Clostridium Difficile Infection Hospitalization 3/31/2011 82 Female 141 lb 10/3/2012 Consumer Us
Primary
Concomitant
Visual Evoked Potentials Abnormal Hospitalization 6/2012 Female 216 lb 9/28/2012 Physician Be
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2012 55 Female 240 lb 11/9/2012 Consumer Us
Primary
Concomitant
Myocardial Infarction Death 8/2/2012 58 Male 9/5/2012 Physician Us
Primary
Concomitant
Rib Fracture Other Serious Male 8/30/2012 Consumer Us
Primary
Concomitant
Vomiting 2010 51 Female 170 lb 9/11/2012 Consumer Us
Primary
Concomitant
Memory Impairment Other Serious 8/2011 87 Male 9/12/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Vomiting Other Serious 10/2011 50 Female 176 lb 9/18/2012 Consumer Us
Primary
Concomitant
Pulmonary Congestion Hospitalization 5/2012 85 Female 9/21/2012 Physician Us
Primary
Concomitant
Rash Female 9/14/2012 Consumer Us
Primary
Concomitant
Retinal Vein Occlusion 8/2012 Male 9/27/2012 Physician Us
Primary
Concomitant
Obesity Hospitalization 2003 40 Male 11/14/2012 Other Health Professional Us
Primary
Concomitant
Fall Death 10/5/2012 84 Female 10/19/2012 Physician Us
Primary
Concomitant
Prostate Infection Hospitalization 9/30/2012 77 Male 146 lb 11/8/2012 Consumer Us
Primary
Concomitant
Trismus Other Serious Female 10/17/2012 Physician Us
Primary
Concomitant
Skin Disorder Other Serious Male 2/25/2013 Consumer De
Primary
Concomitant
Heart Valve Incompetence Hospitalization 10/23/2012 65 Male 291 lb 11/5/2012 Pharmacist Us
Primary
Concomitant
Musculoskeletal Stiffness 10/26/2011 57 Male 11/7/2012 Other Health Professional Us
Primary
Concomitant
Gait Disturbance 59 Female 195 lb 12/3/2012 Consumer Us
Primary
Secondary
Concomitant
Wheezing Other Serious Female 11/7/2012 Consumer Country Not Specified
Primary
Concomitant
Palpitations Other Serious Male 11/8/2012 Consumer Country Not Specified
Primary
Concomitant
Cellulitis Hospitalization 10/14/2012 72 Male 256 lb 11/16/2012 Physician Us
Primary
Concomitant
Tremor 9/28/2012 86 Male 162 lb 12/14/2012 Physician Us
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/20/2012 82 Female 211 lb 11/21/2012 Other Health Professional Ca
Primary
Concomitant
Urosepsis Hospitalization 11/20/2012 77 Male 151 lb 2/21/2013 Consumer Us
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/11/2011 65 Female 182 lb 12/3/2012 Physician Us
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 6/2/2012 61 Male 221 lb 12/5/2012 Consumer Us
Primary
Concomitant
Angioedema Other Serious 11/15/2012 47 Female 177 lb 12/10/2012 Other Health Professional Gb
Primary
Concomitant
Urticaria 9/2012 72 Female 12/19/2012 Physician Us
Primary
Concomitant
Vitamin D Deficiency Other Serious 12/2012 Female 1/25/2013 Physician Us
Primary
Concomitant
Angioedema Other Serious 11/15/2012 47 Female 12/11/2012 Consumer Dk
Concomitant
Diverticulitis Hospitalization 11/2012 Male 175 lb 1/2/2013 Other Health Professional Ca
Primary
Concomitant
Pain 2012 73 Female 170 lb 1/10/2013 Consumer Us
Primary
Concomitant
Drug Ineffective 86 Male 11/27/2012 Consumer Us
Primary
Concomitant
Weight Increased 7/17/2012 82 Male 170 lb 1/18/2013 Consumer Us
Primary
Concomitant
Productive Cough 1/13/2012 54 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
B-cell Lymphoma Recurrent Other Serious 6/2012 Male 1/29/2013 Other Health Professional Us
Primary
Concomitant
Injection Site Pain 1/5/2011 67 Female 145 lb 1/28/2013 Consumer Us
Primary
Concomitant
Psoriasis 2011 Male 165 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Rash Macular 2011 68 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Skin Hypertrophy 2011 52 Male 1/28/2013 Physician Country Not Specified
Primary
Concomitant
Injection Site Haemorrhage 10/11/2012 50 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Tuberculosis 3/2010 62 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Weight Increased 6/22/2012 Female 1/30/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Feeling Abnormal 6/2012 Male 210 lb 2/1/2013 Consumer Us
Primary
Concomitant
Stress 2010 79 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 8/15/2012 87 Male 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriasis 5/2012 69 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Productive Cough 1/2012 45 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Death Death 12/2012 62 Female 1/29/2013 Consumer Us
Primary
Concomitant
Rash 12/2011 68 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 2012 Female 135 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pruritus 4/23/2012 82 Female 135 lb 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Rhinorrhoea 7/7/2012 51 Female 220 lb 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Rash Papular 7/23/2012 62 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Joint Dislocation 6/2012 60 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Muscle Spasms 1/2012 Male 255 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Skin Lesion 10/2012 69 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Malignant Melanoma Other Serious Female 121 lb 3/27/2013 Physician Us
Primary
Concomitant
Paraesthesia Other Serious 7/31/2011 74 Female 120 lb 3/5/2013 Consumer Us
Primary
Secondary
Concomitant
Wheezing 2012 65 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Otitis Media Acute Other Serious 2/19/2013 75 Female 169 lb 4/1/2013 Consumer Us
Primary
Concomitant
Drug Ineffective 2012 71 Female 173 lb 3/4/2013 Consumer Us
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 10/31/2012 53 Female 3/20/2013 Physician Us
Primary
Concomitant
Underdose Other Serious 2/2013 Female 3/8/2013 Consumer Us
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/5/2013 89 Male 3/8/2013 Pharmacist Us
Primary
Concomitant
Drug Ineffective 2012 59 Female 195 lb 10/30/2012 Consumer Us
Primary
Concomitant
Gastroenteritis Viral Hospitalization 2/2013 Male 175 lb 3/25/2013 Consumer Ca
Primary
Concomitant
Influenza Other Serious 2012 73 Male 218 lb 6/21/2012 Pharmacist Us
Primary
Concomitant
Weight Decreased Other Serious 2000 55 Female 153 lb 3/21/2013 Us
Primary
Secondary
Concomitant

Drug Data