Simvastatin combined with Trimethoprim

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 2/4/2006 89 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Metastasis Other Serious 10/15/2001 60 Male 5/12/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/19/2006 36 Female 132 lb 9/5/2006 United Kingdom
Primary
Concomitant
Culture Urine Positive Hospitalization 9/16/2006 71 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 12/5/2006 79 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 12/27/2006 84 Male 1/24/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 2/2/2007 64 Female 3/2/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/2/2007 64 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 6/1/2006 73 Female 3/27/2007 United Kingdom
Primary
Secondary
Concomitant
Chest Pain Other Serious 5/10/2007 55 Male 7/25/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 8/11/2006 82 Male 8/10/2007 Physician United Kingdom
Primary
Concomitant
Metabolic Acidosis Other Serious 1/1/2007 73 Female 9/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/19/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 73 Female 154 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/15/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 154 lb 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 73 Female 9/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Extrapyramidal Disorder Hospitalization 82 Male 12/3/2007
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Disability 8/1/2007 81 Female 119 lb 1/29/2008 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/19/2008 83 Male 2/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Disability 8/1/2007 81 Female 119 lb 5/29/2008 Consumer United Kingdom
Primary
Concomitant
Stomatitis Other Serious 4/26/2008 58 Female 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Skin Discolouration Life Threatening 3/1/2008 62 Male 6/16/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 3/1/2008 62 Male 170 lb 7/2/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 6/12/2008 77 Male 7/18/2008 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 5/3/2008 75 Female 8/8/2008 Physician Australia
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 10/15/2001 60 Male 9/16/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/7/2008 79 Female 11/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Disability 11/13/2008 49 Male 12/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Disability 11/13/2008 49 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/18/2008 81 Female 12/22/2008 Other Health Professional United Kingdom
Primary
Interacting
Rhabdomyolysis Life Threatening 11/18/2008 81 Female 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/7/2008 91 Female 1/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 146 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 146 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 1/23/2009 United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 1/27/2009 United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 1/23/2009 United Kingdom
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 2/12/2009 Physician Netherlands
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 1/12/2005 2/25/2009 Physician Netherlands
Primary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 4/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 7/28/2009 United Kingdom
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 9/6/2009 9/21/2009 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2006 44 Female 210 lb 9/23/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/2/2009 83 Female 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 5/30/2008 Male 9/28/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/2/2002 32 9/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Disability 11/13/2008 49 Male 10/23/2009 United Kingdom
Primary
Concomitant
Uterine Prolapse Other Serious 10/6/2009 Female 10/29/2009 United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 10/14/2009 89 Female 11/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 9/27/2009 67 Male 203 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 9/27/2009 67 Male 11/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/1/2009 Other Health Professional United Kingdom
Primary
Interacting
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/19/2009 71 Male 12/7/2009 Netherlands
Primary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 12/8/2009 Netherlands
Primary
Concomitant
Sepsis Other Serious 10/24/2009 Male 203 lb 12/1/2009 United States
Primary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 12/10/2009 Netherlands
Primary
Concomitant
Urinary Tract Infection Life Threatening 81 Female 12/7/2009 United Kingdom
Primary
Concomitant
Neutropenic Sepsis Life Threatening 3/9/2009 66 Female 115 lb 12/16/2009 Austria
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/18/2008 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 81 Female 12/21/2009 United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 12/17/2009
Primary
Secondary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 1/8/2010 Netherlands
Primary
Concomitant
Melaena Other Serious 11/19/2009 71 Male 1/14/2010 Netherlands
Primary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 2/17/2010 Other Health Professional United Kingdom
Primary
Interacting
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 2/19/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 2/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 11/18/2008 81 Female 2/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 10/24/2009 Male 203 lb 3/16/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/1/2008 81 Female 4/14/2010 United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 3/16/2010 68 Female 207 lb 6/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased 6/1/2008 60 Female 117 lb 7/22/2010 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 7/7/2010 78 Female 8/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 52 Female 8/13/2010 United Kingdom
Primary
Secondary
Concomitant
Tendon Rupture Disability 9/16/2010 56 Male 10/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Bradycardia Hospitalization 85 Male 10/15/2010 United States
Primary
Secondary
Concomitant
Tendon Rupture Disability 9/16/2010 56 Male 10/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Disability 9/16/2010 10/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 10/12/2010 78 Male 148 lb 11/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tendon Rupture Disability 9/16/2010 56 Male 10/26/2010 United Kingdom
Primary
Concomitant
Tendon Rupture Disability 9/16/2010 56 Male 10/28/2010 United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 9/24/2010 72 Female 157 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Disability 9/16/2010 56 Male 10/28/2010 Other Health Professional
Primary
Concomitant
Hypoglycaemia Other Serious 10/12/2010 78 Male 11/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hypoglycaemia Other Serious 10/12/2010 78 Male 11/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hypoglycaemia Other Serious 10/12/2010 78 Male 148 lb 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 12/1/2010 64 Female 187 lb 12/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 9/5/2010 69 Female 12/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/18/2010 69 Female 12/17/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/1/2010 69 Female 12/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 9/5/2010 69 Female 12/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 10/22/2010 69 Female 12/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/5/2010 69 Female 1/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 9/5/2010 69 Female 12/22/2010
Primary
Secondary
Concomitant
Lethargy Other Serious 98 Female 12/23/2010 United Kingdom
Primary
Concomitant
Anxiety Hospitalization 9/5/2010 69 Female 1/3/2011 Other Health Professional
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/1/2010 69 Female 1/13/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Disability 10/1/2010 69 Female 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 98 Female 1/4/2011 Uruguay
Primary
Concomitant
Renal Impairment Hospitalization 10/18/2010 69 Female 1/6/2011 United Kingdom
Primary
Secondary
Concomitant
Methaemoglobinaemia Other Serious 12/17/2010 71 Female 1/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Disability 12/13/2010 70 Female 112 lb 1/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Disability 9/5/2010 69 Female 1/18/2011 Other Health Professional
Primary
Secondary
Concomitant
Amoebic Dysentery Other Serious 2/8/2011 Male 139 lb 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Other Serious 2/8/2011 Male 139 lb 3/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Life Threatening 88 Female 2/22/2011 United Kingdom
Primary
Secondary
Concomitant
Rash Disability Male 139 lb 2/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Amoebic Dysentery Disability Male 139 lb 2/23/2011 United Kingdom
Primary
Concomitant
Cough Hospitalization 12/29/2010 78 Male 146 lb 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Other Serious 98 Female 2/25/2011 United Kingdom
Primary
Concomitant
Urinary Retention Disability 11/13/2008 49 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 12/29/2010 78 Male 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 56 Male 3/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening 3/29/2011 71 Female 141 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/6/2011 93 Female 110 lb 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 5/22/2011 57 6/1/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Lip Swelling Other Serious 5/6/2011 93 Female 110 lb 5/24/2011 Other Health Professional
Primary
Secondary
Concomitant
Tremor Disability 12/13/2010 70 Female 112 lb 6/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 5/15/2011 57 Male 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arthralgia Hospitalization 5/15/2011 57 Male 6/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arthralgia Hospitalization 57 Male 6/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Foot Fracture Other Serious 52 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/15/2011 57 Male 6/20/2011 Other Health Professional
Primary
Secondary
Concomitant
Malaise Hospitalization 5/15/2011 57 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/15/2011 57 Male 6/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pain Hospitalization 5/22/2011 57 Male 6/27/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 57 Male 6/28/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/15/2011 57 Male 6/28/2011 Other Health Professional
Primary
Secondary
Concomitant

Drug Data