Aliskiren combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dyspnoea Hospitalization 5/31/2007 59 Female 227 lb 6/22/2007 Physician United States
Primary
Concomitant
Insomnia Related To Another Mental Condition Hospitalization 5/31/2007 Female 227 lb 12/19/2007 Physician United States
Primary
Concomitant
Hypotension Hospitalization 9/13/2008 82 Female 170 lb 1/7/2009 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/13/2008 82 Female 170 lb 1/13/2009 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/13/2008 82 Female 170 lb 4/21/2009 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/13/2008 82 Female 170 lb 4/22/2009 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 176 lb 6/29/2009 Physician United Kingdom
Primary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 10/19/2009 Male 309 lb 11/9/2009 Physician Germany
Primary
Secondary
Concomitant
Gastritis Other Serious 10/19/2009 Male 309 lb 11/12/2009 Physician Germany
Primary
Secondary
Concomitant
Gastritis Other Serious 10/19/2009 Male 309 lb 11/12/2009 Physician Germany
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 5/31/2007 Female 227 lb 11/30/2009 Physician United States
Primary
Concomitant
Tachycardia Other Serious 10/27/2009 Male 198 lb 12/9/2009 Physician Denmark
Primary
Secondary
Concomitant
Tachycardia Other Serious 10/27/2009 Male 198 lb 12/22/2009 Physician Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 68 Male 1/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/10/2009 Female 3/2/2010 Physician
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 3/6/2010 Male 177 lb 3/12/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 3/6/2010 Male 177 lb 3/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Vomiting 6/5/2007 59 Female 140 lb 7/13/2010 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/17/2010 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 2/19/2010 51 Male 150 lb 8/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 2/19/2010 51 Male 150 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 8/13/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/1/2009 59 Female 199 lb 8/20/2010 Physician United States
Primary
Concomitant
Pruritus Other Serious 8/13/2010 60 Male 225 lb 9/9/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 5/10/2010 81 Male 256 lb 9/9/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 5/10/2010 81 Male 256 lb 9/23/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/7/2010 80 Female 183 lb 9/24/2010 Physician Canada
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 5/10/2010 81 Male 256 lb 10/1/2010 Physician United States
Primary
Secondary
Concomitant
Oedema Other Serious 68 Male 201 lb 10/7/2010 Other Health Professional Brazil
Primary
Concomitant
Weight Increased Other Serious 62 Female 174 lb 10/7/2010 Physician Brazil
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 67 Female 207 lb 10/21/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 8/18/2010 64 Male 148 lb 10/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 12/1/2008 75 Female 12/1/2010 Physician Germany
Primary
Concomitant
Rash Generalised Hospitalization 11/2/2010 80 Female 12/8/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 8/1/2010 81 Male 163 lb 12/9/2010 Physician Germany
Primary
Secondary
Concomitant
Sarcoidosis Hospitalization 8/1/2010 1/12/2011 Physician Netherlands
Primary
Concomitant
Concomitant Disease Progression Hospitalization 12/1/2010 38 Male 170 lb 1/19/2011 Physician France
Primary
Secondary
Concomitant
Arrhythmia Life Threatening 2/19/2010 51 Male 150 lb 1/20/2011 Physician Brazil
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 11/6/2010 64 Female 182 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/1/2010 73 Male 2/24/2011 Physician Belgium
Primary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 12/22/2010 38 Male 170 lb 3/3/2011 Physician France
Primary
Secondary
Concomitant
Dizziness Hospitalization 3/3/2010 71 Male 229 lb 3/3/2011 Physician Ireland
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 2/9/2011 66 Female 3/1/2011 Physician Brazil
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death Male 185 lb 3/4/2011 Physician Brazil
Primary
Secondary
Concomitant
Pruritus Hospitalization 8/13/2010 60 Male 225 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Hernia Repair Other Serious 4/25/2010 75 Male 199 lb 3/7/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 81 Female 2/22/2011 Consumer Brazil
Primary
Concomitant
Pneumonia Hospitalization 4/25/2010 75 Male 199 lb 3/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/3/2010 71 Male 229 lb 3/14/2011 Physician Ireland
Primary
Secondary
Concomitant
Fibrin D Dimer Increased Hospitalization 6/1/2009 59 Female 199 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Other Serious 6/3/2009 61 Male 203 lb 4/11/2011 Physician Germany
Primary
Concomitant
Hyponatraemia Other Serious 2/25/2011 71 Female 148 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 12/1/2009 77 Female 130 lb 4/25/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious Male 176 lb 4/20/2011 Physician Germany
Primary
Concomitant
Ocular Vascular Disorder Hospitalization 4/10/2009 72 Male 256 lb 4/27/2011 Physician Germany
Primary
Concomitant
Heart Rate Decreased Hospitalization 4/24/2009 65 Male 181 lb 4/29/2011 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Chronic Life Threatening 11/29/2010 58 Male 188 lb 4/29/2011 Physician Germany
Primary
Secondary
Concomitant
Abdominal Pain Upper Female 200 lb 5/19/2011 Consumer United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 3/3/2009 65 Male 165 lb 5/20/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/3/2009 65 Male 165 lb 5/20/2011 Physician Germany
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 6/3/2009 61 Male 203 lb 5/28/2011 Physician Germany
Primary
Concomitant
Diarrhoea Female 200 lb 6/6/2011 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 16 Female 141 lb 6/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 3/2/2010 73 Male 227 lb 6/14/2011 Physician Germany
Primary
Secondary
Concomitant
Glaucoma Other Serious 2/18/2010 Male 198 lb 6/15/2011 Physician Germany
Primary
Concomitant
Condition Aggravated Other Serious 16 Female 141 lb 6/6/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Platelet Count Decreased Death 5/17/2011 74 Male 6/28/2011 Physician Italy
Primary
Concomitant
Hepatic Steatosis Other Serious 2/19/2009 67 Male 223 lb 6/30/2011 Physician Germany
Primary
Secondary
Concomitant
Hypertension Disability 8/23/2010 56 Male 287 lb 7/5/2011 Physician Germany
Primary
Secondary
Concomitant
Death Death 2/19/2009 67 Male 223 lb 7/7/2011 Physician Germany
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 1/20/2010 69 Male 198 lb 7/11/2011 Physician Germany
Primary
Secondary
Concomitant
Headache Hospitalization 12/22/2009 54 Male 238 lb 7/11/2011 Physician Netherlands
Primary
Concomitant
Atrial Flutter Hospitalization 11/9/2009 66 Male 168 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 7/9/2009 66 Female 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 7/9/2009 66 Female 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Feeling Abnormal Hospitalization 1/1/2003 Female 150 lb 7/13/2011 Consumer Brazil
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 3/3/2009 65 Male 165 lb 7/14/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 3/3/2009 65 Male 165 lb 7/14/2011 Physician Germany
Primary
Secondary
Concomitant
Hemiplegia Other Serious 2/1/2010 67 Male 223 lb 7/15/2011 Physician Germany
Primary
Secondary
Concomitant
Refractory Anaemia Disability 8/23/2010 56 Male 287 lb 7/15/2011 Physician Germany
Primary
Secondary
Concomitant
Oedema Death 8/16/2010 76 Male 212 lb 7/21/2011 Physician Germany
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious Male 7/29/2011 Physician Germany
Primary
Secondary
Angina Pectoris Other Serious Male 7/29/2011 Physician Germany
Primary
Secondary
Hypoglycaemia Other Serious 2/1/2010 67 Male 223 lb 7/29/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/14/2011 67 Male 223 lb 9/2/2011 Physician Germany
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Death 2/1/2010 67 Male 223 lb 9/12/2011 Physician Germany
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 3/6/2010 67 Male 176 lb 9/28/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 11/29/2010 58 Male 188 lb 9/30/2011 Physician Germany
Primary
Secondary
Concomitant
Duodenal Neoplasm Hospitalization 8/23/2011 70 Female 179 lb 10/5/2011 Other Health Professional United States
Primary
Concomitant
Angioedema Other Serious 5/1/2011 70 Female 10/11/2011 Physician Germany
Primary
Secondary
Concomitant
Hypotension Life Threatening 3/6/2010 67 Male 176 lb 10/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 5/1/2009 10/26/2011 Physician Brazil
Primary
Secondary
Concomitant
Syncope Hospitalization 10/17/2011 74 Female 10/28/2011 Physician Italy
Primary
Concomitant
Bilirubinuria Other Serious 3/9/2009 50 Male 11/2/2011 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 16 Female 141 lb 11/4/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Pelvic Mass Hospitalization 8/23/2011 70 Female 179 lb 11/15/2011 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/3/2011 68 Male 161 lb 11/16/2011 Physician Germany
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 10/3/2011 66 Male 265 lb 11/28/2011 Physician United States
Primary
Concomitant
Localised Infection Hospitalization 11/29/2010 58 Male 188 lb 12/2/2011 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Life Threatening 11/29/2010 58 Male 157 lb 12/6/2011 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Hospitalization 11/29/2010 58 Male 157 lb 12/12/2011 Physician Germany
Primary
Secondary
Concomitant
Lethargy Other Serious Female 101 lb 12/26/2011 Physician Netherlands
Primary
Concomitant
Atrial Flutter Other Serious 1/4/2012 66 Male 213 lb 1/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Lip Swelling Other Serious 5/1/2011 70 Female 1/25/2012 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/14/2010 78 Male 212 lb 1/27/2012 Physician Poland
Primary
Secondary
Concomitant
Bradyarrhythmia Hospitalization 9/14/2010 78 Male 212 lb 1/27/2012 Physician Poland
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 1/4/2012 66 Male 213 lb 2/6/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Expired Drug Administered Hospitalization 11/21/2011 55 Male 163 lb 2/16/2012 Consumer Brazil
Primary
Secondary
Concomitant
Hypotension Hospitalization 8/14/2011 67 Male 223 lb 2/22/2012 Physician Germany
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 8/23/2011 70 Female 179 lb 2/27/2012 Other Health Professional United States
Primary
Concomitant
Concomitant Disease Progression Hospitalization 3/3/2010 71 Male 229 lb 3/5/2012 Physician Ireland
Primary
Secondary
Concomitant
Hypotension Hospitalization 8/14/2011 67 Male 223 lb 3/8/2012 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/14/2011 67 Male 223 lb 3/8/2012 Physician Germany
Primary
Secondary
Concomitant
Obstruction Death 8/23/2011 70 Female 179 lb 3/8/2012 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2012 69 Male 3/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 3/1/2011 70 Female 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
Hypothyroidism Other Serious Male 218 lb 4/11/2012 United Kingdom
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2012 78 Male 193 lb 4/17/2012 Physician Poland
Primary
Concomitant
Cardiovascular Event Prophylaxis Hospitalization 5/23/2011 68 Female 172 lb 4/20/2012 Physician Germany
Primary
Concomitant
Angina Pectoris Hospitalization 6/1/2011 74 Male 5/4/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/13/2012 73 Male 5/22/2012 Physician Austria
Primary
Concomitant
Cerebrovascular Accident Disability 3/28/2012 61 Male 212 lb 5/22/2012 Physician Poland
Primary
Secondary
Concomitant
Back Pain Hospitalization 4/18/2012 72 Male 183 lb 5/31/2012 Physician Germany
Primary
Concomitant
Hyponatraemia Other Serious 2/25/2011 71 Female 148 lb 6/20/2012 Physician United States
Primary
Secondary
Concomitant
Blindness Other Serious 1/1/2004 26 Male 148 lb 6/27/2012 Consumer Brazil
Primary
Secondary
Concomitant
Cardiogenic Shock Death 6/3/2012 67 Female 170 lb 6/28/2012 Physician Brazil
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2012 78 Male 193 lb 7/10/2012 Physician Poland
Primary
Concomitant
Hypotonia Other Serious 6/25/2012 62 Male 212 lb 7/16/2012 Other Health Professional Poland
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 63 Female 7/31/2012 Consumer Germany
Primary
Concomitant
Vertigo Death 3/6/2010 67 Male 176 lb 6/25/2013 Physician Ru
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 12/22/2010 39 Male 170 lb 8/26/2013 Physician Fr
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/7/2011 47 Male 225 lb 9/6/2013 Physician Be
Primary
Secondary
Concomitant
Urosepsis Hospitalization 4/2011 54 Male 12/31/2012 Physician De
Primary
Concomitant
Polycythaemia Hospitalization 4/13/2012 74 Male 12/12/2012 Physician At
Primary
Concomitant
Syncope Life Threatening 5/24/2012 68 Male 288 lb 9/26/2013 Physician De
Primary
Concomitant
Myocardial Ischaemia Hospitalization Male 159 lb 10/31/2012 Physician Za
Primary
Concomitant
Suicidal Ideation Hospitalization 11/12/2010 39 Male 369 lb 11/2/2012 Physician Us
Primary
Concomitant
Stevens-johnson Syndrome Death 11/6/2010 64 Female 182 lb 11/28/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/11/2011 65 Female 182 lb 12/3/2012 Physician Us
Primary
Secondary
Concomitant
Renal Disorder Other Serious 9/7/2010 82 Female 112 lb 8/28/2013 Other Health Professional Br
Primary
Secondary
Concomitant
Vertigo Hospitalization 11/4/2011 55 Female 227 lb 8/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Melaena Hospitalization Male 180 lb 9/6/2013 Consumer Us
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/28/2010 62 Male 201 lb 7/21/2013 Physician De
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 58 Male 5/27/2013 Other Health Professional Us
Primary
Concomitant
Toxicity To Various Agents Death 6/20/2013 74 Male 173 lb 9/9/2013 Physician Ie
Primary
Secondary
Concomitant
Coronary Artery Restenosis Hospitalization 9/24/2010 65 Male 229 lb 8/23/2013 Physician Es
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/18/2011 69 Female 154 lb 8/27/2013 Physician Hu
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/24/2009 79 Female 134 lb 8/28/2013 Physician Us
Primary
Concomitant

Drug Data