Gliclazide combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Scar Death 6/2/2005 72 Female 143 lb 12/30/2005 South Africa
Primary
Concomitant
Aortic Aneurysm Rupture Death 11/21/2003 Male 1/4/2006 France
Primary
Concomitant
Bone Marrow Failure Other Serious 9/13/2004 Male 1/4/2006 Australia
Primary
Concomitant
Oedema Hospitalization Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Scar Other Serious 1/1/2003 69 Female 150 lb 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Facial Palsy Other Serious 12/18/2005 67 Female 143 lb 2/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 9/24/2004 72 Female 2/10/2006 Physician United Kingdom
Primary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 2/17/2006 Poland
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/9/2005 77 Male 220 lb 2/21/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 5/9/2005 77 Male 220 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/24/2004 72 Female 3/2/2006 United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 9/24/2004 72 Female 3/2/2006 United Kingdom
Primary
Concomitant
Skin Cancer Life Threatening 5/9/2005 77 Male 220 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/24/2004 72 Female 3/21/2006 Physician United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 48 Male 240 lb 4/27/2006 Physician United Kingdom
Primary
Concomitant
Renal Cyst Hospitalization 2/14/2005 63 Male 185 lb 4/25/2006 Poland
Primary
Secondary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/3/2006 Pharmacist Canada
Primary
Concomitant
Coma Life Threatening 10/29/2005 79 Female 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Death 87 Male 5/5/2006 Consumer Canada
Primary
Concomitant
Hypertension Other Serious 12/14/2005 62 Male 5/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Microalbuminuria Hospitalization 5/6/2006 67 Female 106 lb 5/23/2006 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/24/2006 Physician United Kingdom
Primary
Concomitant
Lethargy Other Serious 4/24/2006 72 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Required Intervention 8/26/2005 77 Male 5/30/2006 Physician Ireland
Primary
Concomitant
Hypoglycaemia Hospitalization 5/6/2006 67 Female 106 lb 6/26/2006 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2006 81 Female 7/28/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 71 Female 8/18/2006 Denmark
Primary
Concomitant
Hypoglycaemia Other Serious 6/3/2006 81 Female 8/21/2006 United Kingdom
Primary
Concomitant
Oedema Life Threatening 6/16/2006 Male 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/26/2006 71 Male 9/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Life Threatening 6/16/2006 Male 9/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Self-injury Other Serious 39 Female 154 lb 9/14/2006 Physician United Kingdom
Primary
Concomitant
Mobility Decreased Hospitalization 5/6/2006 67 Female 106 lb 9/22/2006 Physician United Kingdom
Primary
Concomitant
Intentional Self-injury Other Serious 39 Female 154 lb 9/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nerve Compression Hospitalization 6/1/2006 Female 10/5/2006 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 8/1/2006 66 Male 187 lb 10/4/2006 United Kingdom
Primary
Concomitant
Pain In Extremity Disability 9/1/2006 64 Female 207 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/1/2006 Physician United Kingdom
Primary
Concomitant
Sympathectomy Hospitalization 4/28/2003 95 Female 141 lb 11/14/2006 United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 11/13/2006 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/2/2006 63 Male 194 lb 11/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Facial Palsy Disability 10/20/2006 Female 117 lb 11/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hip Fracture Hospitalization 5/6/2006 Female 106 lb 11/27/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 5/6/2005 60 Female 11/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 9/15/2006 80 Male 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/26/2006 72 Male 11/28/2006 Pharmacist United Kingdom
Primary
Concomitant
Mouth Injury Other Serious 11/22/2006 Male 134 lb 12/7/2006 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/24/2006 66 Female 209 lb 12/14/2006 Physician Greece
Primary
Concomitant
Cardiac Hypertrophy Death 11/15/2006 51 Female 252 lb 12/11/2006 Physician United Kingdom
Primary
Concomitant
Lethargy Other Serious 11/6/2006 76 Female 12/13/2006 Pharmacist United Kingdom
Primary
Concomitant
Infusion Related Reaction Hospitalization 11/24/2006 66 Female 209 lb 12/22/2006 Physician Greece
Primary
Concomitant
Hypoglycaemia Hospitalization 68 Male 12/15/2006 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2006 34 Male 359 lb 1/3/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Hallucination Disability 69 Female 1/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Hospitalization 9/25/2006 76 Female 1/9/2007 United Kingdom
Primary
Concomitant
Mouth Injury Other Serious 11/22/2006 Male 143 lb 1/19/2007 Physician United Kingdom
Primary
Concomitant
Oedema Life Threatening 6/16/2006 Male 1/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/25/2006 76 Female 1/18/2007 United Kingdom
Primary
Concomitant
Oedema Life Threatening 6/16/2006 61 Male 1/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 1/31/2007 Physician Australia
Primary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 2/9/2007 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 1/12/2007 52 Male 205 lb 2/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hip Fracture Hospitalization 5/6/2006 Female 106 lb 3/5/2007 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 3/9/2007 Other Health Professional France
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/8/2007 86 Male 3/12/2007 Physician
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/14/2005 Female 201 lb 3/14/2007 Physician United Kingdom
Primary
Concomitant
Aggression Other Serious 1/1/1999 68 Male 3/22/2007 Consumer United Kingdom
Primary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nightmare Other Serious 1/1/1999 68 Male 4/10/2007 Consumer United Kingdom
Primary
Concomitant
Orthopnoea Other Serious 5/1/2006 70 Male 179 lb 4/10/2007 Consumer United Kingdom
Primary
Concomitant
Aggression Other Serious 1/1/1999 68 Male 4/6/2007 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/1/2007 47 Male 154 lb 4/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2007 51 Female 265 lb 4/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Fall Other Serious 11/22/2006 Male 143 lb 4/19/2007 Physician United Kingdom
Primary
Concomitant
Nightmare Other Serious 1/1/1999 68 Male 229 lb 4/24/2007 Consumer United Kingdom
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 3/27/2007 74 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nightmare Other Serious 1/1/1999 68 Male 229 lb 4/26/2007 Physician United Kingdom
Primary
Concomitant
Renal Artery Stenosis Other Serious 3/3/2006 75 Male 198 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 4/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death Male 174 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hypersensitivity Other Serious 58 Female 218 lb 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 6/3/2006 81 Female 5/18/2007 Physician Denmark
Primary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 5/24/2007 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Dyskinesia Other Serious 2/9/2007 43 Female 181 lb 5/30/2007 Physician United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Sudden Death Life Threatening 5/19/2007 Male 181 lb 6/13/2007 Other Health Professional
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 67 Male 251 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 6/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 6/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Life Threatening 5/19/2007 Male 181 lb 6/26/2007 Other Health Professional
Primary
Secondary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/8/2007 71 Male 142 lb 6/28/2007 Physician United Kingdom
Primary
Concomitant
Sleep Terror Disability 3/1/2007 67 Male 7/6/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 6/1/2006 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Local Swelling Hospitalization 5/6/2006 Female 117 lb 7/12/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/17/2007
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 8/14/2006 67 Male 7/13/2007 United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/1/2006 67 Male 7/23/2007 Physician United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/15/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 6/27/2007 47 Male 229 lb 8/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Heart Rate Increased Hospitalization 4/1/2007 62 Female 245 lb 8/10/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 6/5/2007 51 Male 8/14/2007 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 7/24/2007 57 Male 219 lb 8/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 7/24/2007 57 Male 219 lb 8/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 8/28/2007 Other Health Professional France
Primary
Concomitant
Cardiac Failure Acute Death 65 Female 190 lb 8/30/2007 Consumer United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious 7/30/2007 Female 157 lb 8/31/2007 United Kingdom
Primary
Concomitant
Vision Blurred Required Intervention 8/15/2007 68 Male 9/7/2007 United Kingdom
Primary
Concomitant
Alopecia Other Serious 6/25/2007 42 Female 209 lb 9/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Hospitalization 9/1/2007 83 Female 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious 8/14/2006 67 Male 10/9/2007 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 7/24/2007 57 Male 219 lb 10/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/1/2005 77 Female 11/5/2007 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 59 Male 11/1/2007 United Kingdom
Primary
Concomitant
Angina Unstable Life Threatening 5/19/2007 Male 181 lb 11/7/2007 Other Health Professional
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/17/2007 55 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/1/2007 59 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/19/2007 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Blistering Other Serious 8/11/2007 77 Female 11/16/2007 Other Health Professional France
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 53 Female 11/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Hypomagnesaemia Hospitalization 10/29/2007 80 Male 11/26/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Required Intervention 10/25/2007 73 Male 11/29/2007 United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Life Threatening 10/25/2007 73 Male 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Life Threatening 10/15/2007 73 Male 11/30/2007 Other Health Professional Denmark
Primary
Concomitant
Pleural Effusion Hospitalization 1/1/2007 72 Male 12/13/2007 Consumer United Kingdom
Primary
Concomitant
Hepatitis Fulminant Hospitalization 7/1/2007 85 Male 154 lb 12/22/2007 Physician
Primary
Concomitant
Duodenal Ulcer Perforation Life Threatening 10/25/2007 73 Male 12/21/2007
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 11/2/2007 68 Male 176 lb 1/8/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 1/1/2006 68 Male 198 lb 1/11/2008 Consumer United Kingdom
Primary
Concomitant

Drug Data