Carbamazepine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 9/2/2003 Male 1/4/2006 Finland
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 8/10/2004 50 Male 1/25/2006 Physician Brazil
Primary
Concomitant
Hyperglycaemia Hospitalization 11/9/2005 62 Male 1/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/14/2005 Male 236 lb 12/28/2005 Pharmacist United States
Primary
Concomitant
Suicide Attempt Hospitalization Female 3/8/2006 United States
Primary
Concomitant
Pneumonia Staphylococcal Hospitalization 8/22/2005 80 Male 191 lb 12/27/2005 Consumer United States
Primary
Concomitant
Sudden Death Death 2/28/2006 72 Male 3/22/2006 United States
Primary
Concomitant
Sudden Death Death 3/1/2006 72 Male 4/7/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2002 60 Female 4/28/2006 Other Health Professional Norway
Primary
Concomitant
Cardiac Arrest Required Intervention 6/15/2006 63 Male 223 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 5/17/2006 65 Male 6/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pyrexia Hospitalization 5/15/2006 38 Male 234 lb 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/14/2006 Male 150 lb 7/19/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 5/17/2006 65 Female 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Visual Acuity Reduced Life Threatening 1/10/2006 Female 146 lb 9/7/2006 Physician Germany
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 3/31/2006 64 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 10/1/2006 47 Male 215 lb 12/22/2006 Physician Germany
Primary
Concomitant
Sepsis Death 12/21/2006 79 Female 126 lb 12/29/2006 Physician Germany
Primary
Concomitant
Septic Shock Death 12/21/2006 79 Female 126 lb 1/5/2007 Other Health Professional Germany
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 1/25/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Nervous System Disorder Required Intervention 65 Female 143 lb 1/30/2007 United Kingdom
Primary
Secondary
Concomitant
Umbilical Hernia Hospitalization 8/12/2006 37 Male 4/5/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 2/6/2007 79 Male 187 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 2/20/2007 68 Female 4/16/2007 United Kingdom
Primary
Concomitant
Staring 4/6/2007 44 Male 255 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Death Hospitalization 7/13/2006 Male 159 lb 5/9/2007 United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 7/13/2006 Male 159 lb 5/25/2007 United Kingdom
Primary
Concomitant
Mini Mental Status Examination Abnormal Other Serious 64 Male 5/25/2007 United States
Primary
Concomitant
Death Death 12/21/2006 Female 126 lb 6/5/2007 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 65 Male 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Head Injury Other Serious 62 Male 8/24/2007 United Kingdom
Primary
Secondary
Tachycardia Other Serious 62 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Hospitalization 1/4/2006 82 Female 9/4/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Viral Infection Hospitalization 2/22/2005 35 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Death 7/14/2007 Female 154 lb 10/12/2007 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Death 7/14/2007 Female 154 lb 11/6/2007 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/31/2008 50 Female 3/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 25 Male 4/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2007 25 Male 4/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/3/2007 Male 209 lb 6/11/2008 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Required Intervention 62 Male 6/13/2008
Primary
Secondary
Tachycardia Required Intervention 62 Male 7/7/2008
Primary
Secondary
Tachycardia Other Serious 62 Male 7/11/2008 United Kingdom
Primary
Secondary
Speech Disorder Other Serious Male 246 lb 8/6/2008 Consumer United States
Primary
Concomitant
Skin Burning Sensation 6/25/2008 Male 8/29/2008 United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 5/20/2008 45 Female 139 lb 8/8/2008 Physician United States
Primary
Concomitant
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Hypocalcaemia Hospitalization 9/14/2008 Male 10/3/2008 Physician United States
Primary
Concomitant
Pallor Hospitalization Female 220 lb 10/24/2008 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 69 Male 11/3/2008 Physician Sweden
Primary
Secondary
Concomitant
Convulsion Other Serious 10/26/2008 55 Male 10/31/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 8/10/2008 71 Male 11/6/2008 Netherlands
Primary
Concomitant
Hyponatraemia Hospitalization 7/18/2007 84 Female 11/6/2008 United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 84 Female 11/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/18/2007 84 Female 11/12/2008 United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Male 11/20/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Constipation 1/4/2009 59 Female 130 lb 2/16/2009 Consumer United States
Primary
Concomitant
Tinnitus Hospitalization 2/9/2009 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Glomerulonephritis Membranous Hospitalization 65 Male 3/2/2009 Physician United Kingdom
Primary
Concomitant
Vertigo Hospitalization 3/16/2007 79 Female 148 lb 3/5/2009 Other Health Professional Austria
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 1/19/2009 Male 157 lb 2/26/2009 Consumer Canada
Primary
Concomitant
Angina Pectoris Other Serious 1/31/2009 Male 157 lb 2/26/2009 Consumer Canada
Primary
Concomitant
Tinnitus Hospitalization 2/9/2009 Male 3/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2009 48 Male 176 lb 3/20/2009 Other Health Professional Germany
Primary
Secondary
Personality Change Hospitalization 1/21/2009 48 Male 3/21/2009 Other Health Professional Germany
Primary
Secondary
Vulvovaginal Candidiasis Hospitalization 1/19/2001 33 Female 295 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Vomiting 10/16/2008 59 Male 194 lb 12/29/2008 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 4/8/2009 69 Male 5/7/2009 Other Health Professional Germany
Primary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Tinnitus Hospitalization 2/9/2009 Male 5/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Yellow Skin Other Serious 5/1/2007 67 Male 165 lb 5/11/2009 Physician United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 6/21/2006 66 Male 165 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2006 Male 5/21/2009 Consumer Brazil
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/28/2009 74 Male 6/5/2009
Primary
Concomitant
Transaminases Increased Hospitalization 4/8/2009 Male 220 lb 6/30/2009 Other Health Professional Germany
Primary
Concomitant
Visual Impairment 5/6/2009 Female 6/30/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Epilepsy 6/19/2009 55 Male 183 lb 7/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lacunar Infarction Other Serious 4/1/2009 46 Male 8/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pollakiuria Other Serious 3/1/2009 Female 154 lb 8/12/2009 Consumer Brazil
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 5/9/2006 49 Female 210 lb 8/13/2009 United States
Primary
Concomitant
Pyrexia Other Serious 65 Male 190 lb 8/25/2009 Physician United Kingdom
Primary
Concomitant
Angina Pectoris 7/16/2007 Female 192 lb 8/27/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/23/2009 72 Female 137 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/21/2009 Female 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Overdose Life Threatening 8/5/2009 45 Male 9/2/2009 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Life Threatening 8/13/2009 Female 154 lb 9/24/2009 Physician
Primary
Concomitant
Retinal Haemorrhage Disability Male 9/28/2009 Consumer
Primary
Concomitant
Syncope Other Serious 62 Male 9/24/2009 United Kingdom
Primary
Secondary
Concomitant
Retinal Haemorrhage Disability Male 10/2/2009 Physician
Primary
Concomitant
Memory Impairment Other Serious 8/25/2009 68 Male 146 lb 10/8/2009 Consumer Brazil
Primary
Concomitant
Retinal Haemorrhage Disability 1/1/2009 Male 10/9/2009 Physician
Primary
Concomitant
Vomiting Other Serious 8/21/2009 Female 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 4/15/2009 54 Male 134 lb 10/14/2009 Physician Switzerland
Primary
Concomitant
Poisoning Life Threatening 8/5/2009 Male 10/16/2009 Physician Netherlands
Primary
Concomitant
Atrial Flutter Other Serious 62 Male 10/21/2009 United Kingdom
Primary
Secondary
Bundle Branch Block Right Other Serious 62 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/21/2009 48 Male 176 lb 11/9/2009 Other Health Professional Germany
Primary
Secondary
Urinary Incontinence Hospitalization 59 Female 157 lb 12/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/7/2009 Female 1/6/2010 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 137 lb 1/17/2010 Consumer Brazil
Primary
Concomitant
Death Death Male 171 lb 1/19/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2005 Female 165 lb 2/12/2010 Brazil
Primary
Concomitant
Ear Pain Other Serious Female 2/15/2010 Pharmacist United Kingdom
Primary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 12/15/2009 Female 110 lb 1/15/2010 Pharmacist United States
Primary
Concomitant
Dermatitis Exfoliative Other Serious 1/6/2010 52 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Leiomyoma Hospitalization 12/1/2009 48 Female 134 lb 3/19/2010 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 2/13/2010 78 Male 3/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 10/27/2009 61 Male 4/28/2010 Germany
Primary
Secondary
Concomitant
Fall Other Serious 64 Female 5/3/2010 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 64 Female 5/5/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/2/2010 71 Male 7/8/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tremor Other Serious 11/1/2008 64 Female 99 lb 7/23/2010 Consumer Brazil
Primary
Concomitant
Tablet Issue Other Serious 5/1/2010 64 Male 223 lb 7/16/2010 United States
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 6/1/2009 71 Female 187 lb 7/28/2010 Consumer Brazil
Primary
Secondary
Concomitant
Dementia Alzheimer's Type Other Serious 6/1/2009 71 Female 187 lb 8/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Speech Disorder Other Serious 5/1/2010 64 Male 223 lb 7/30/2010 United States
Primary
Concomitant
Nervousness 83 Female 8/18/2010 Consumer United States
Primary
Concomitant
Hepatic Steatosis Death 42 Male 238 lb 8/18/2010 Physician United Kingdom
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9/10/2010 Other Health Professional Singapore
Primary
Secondary
Somnolence 11/1/2009 86 Female 132 lb 9/14/2010 Consumer United States
Primary
Concomitant
Convulsion Other Serious 3/1/2010 65 Male 250 lb 9/14/2010 Consumer United States
Primary
Concomitant
Intentional Drug Misuse 5/1/2010 48 Female 207 lb 9/17/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 3/1/2003 52 Male 292 lb 9/20/2010 United States
Primary
Concomitant
Suicide Attempt Other Serious Female 185 lb 9/20/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 64 Male 144 lb 9/21/2010 United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 10/1/2009 64 Male 203 lb 9/30/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 4/28/2010 59 Male 183 lb 10/8/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 5/12/2010 62 Female 128 lb 10/15/2010 Physician Germany
Primary
Concomitant
Hypothyroidism Hospitalization 12/22/2009 56 Female 150 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 10/7/2010 47 Female 10/26/2010 Other Health Professional Brazil
Primary
Concomitant
Poor Peripheral Circulation Other Serious 10/1/2009 64 Male 203 lb 11/3/2010 Physician United States
Primary
Concomitant
Angina Pectoris 7/16/2007 48 Female 192 lb 11/9/2010 Consumer United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 10/1/2009 64 Male 203 lb 11/10/2010 Physician United States
Primary
Concomitant
Injection Site Erythema Other Serious Female 11/5/2010 Brazil
Primary
Concomitant
Cough Other Serious Female 11/18/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 7/2/2010 69 Female 176 lb 11/22/2010 Physician Germany
Primary
Concomitant

Drug Data