Diclofenac combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Loss Of Consciousness Hospitalization 8/1/2005 59 Male 1/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/21/2005 Male 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 151 lb 2/17/2006 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/22/2006 79 Male 3/8/2006 United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 151 lb 3/27/2006 Physician Germany
Primary
Concomitant
Shoulder Pain Other Serious 3/4/2006 69 Female 4/6/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/30/2006 46 Female 172 lb 4/12/2006 Physician Belgium
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Other Serious 3/4/2006 69 Female 143 lb 4/12/2006
Primary
Secondary
Concomitant
Shoulder Pain Other Serious 3/4/2006 69 Female 4/13/2006 United Kingdom
Primary
Secondary
Concomitant
Shoulder Pain Life Threatening 3/4/2006 69 Female 143 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 65 Female 5/10/2006
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/19/2005 65 Female 176 lb 5/11/2006
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 70 Female 6/6/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 5/17/2006 65 Female 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/17/2006 65 Male 6/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Serotonin Syndrome Hospitalization 70 Female 6/22/2006 Physician Australia
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 70 Female 7/20/2006 Physician Australia
Primary
Secondary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/17/2006 65 Female 8/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vitreous Haemorrhage Required Intervention 2/9/2003 84 Male 8/8/2006 Denmark
Primary
Concomitant
Haematemesis Other Serious 2/22/2006 79 Male 8/8/2006 Denmark
Primary
Concomitant
Stomach Discomfort Other Serious 3/15/2006 Male 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Joint Swelling Hospitalization 7/6/2006 62 Male 8/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 64 Female 9/7/2006 Denmark
Primary
Concomitant
Obstruction Other Serious 6/28/2006 Female 205 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 70 Female 9/28/2006
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 10/3/2006 74 Male 210 lb 10/12/2006 Pharmacist United States
Primary
Concomitant
Neoplasm Malignant Other Serious Female 205 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death Male 174 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2006 Female 269 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/5/2005 Female 269 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 39 Male 6/25/2007 Consumer Italy
Primary
Secondary
Feeling Jittery Other Serious 6/1/2007 Male 213 lb 7/5/2007 United States
Primary
Concomitant
Paraesthesia Other Serious 6/10/2007 69 Female 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 6/10/2007 69 Female 7/5/2007 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 39 Male 7/11/2007
Primary
Secondary
Urinary Tract Infection Hospitalization 10/10/2006 Male 190 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Jittery Other Serious 6/1/2007 Male 213 lb 8/8/2007 United States
Primary
Concomitant
Myoclonus Disability 5/16/2007 56 Female 8/10/2007
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 11/21/2006 Male 8/21/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 8/23/2007 United Kingdom
Primary
Concomitant
Myoclonus Disability 5/15/2007 56 Female 9/3/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 5/16/1997 69 Female 8/30/2007 Physician Netherlands
Primary
Secondary
Concomitant
Swelling Face Hospitalization 42 Male 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Myoclonus Other Serious 56 Female 8/31/2007 United Kingdom
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 8/22/2007 65 Male 9/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 6/10/2007 72 Male 10/22/2007 Physician Sweden
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 121 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 8/1/2007 69 Male 12/5/2007 Consumer United States
Primary
Concomitant
Wrong Drug Administered Death 12/8/2007 Male 155 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 11/22/2007 63 Female 143 lb 12/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious Male 12/20/2007 Physician
Primary
Concomitant
Pneumonia Other Serious Male 12/21/2007 Physician
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 1/8/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Respiratory Depression Other Serious 11/29/2007 46 Female 1/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sleep Apnoea Syndrome Other Serious 11/29/2007 46 Female 2/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Injection Site Pain 11/25/2007 Male 139 lb 3/15/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 3/17/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Large Intestine Perforation Other Serious 70 Female 3/31/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 3/5/2008 Male 251 lb 5/8/2008 Consumer United Kingdom
Primary
Concomitant
Blood Phosphorus Increased Hospitalization 5/8/2008 66 Female 5/15/2008 Pharmacist United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/29/2008 Male 5/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/1999 Male 5/16/2008 Physician United Kingdom
Primary
Concomitant
Glossodynia Other Serious 3/2/2008 Female 5/19/2008 France
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 195 lb 5/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Stent Occlusion Hospitalization 2/28/2008 Female 195 lb 5/23/2008 Physician United States
Primary
Concomitant
Feeling Cold 3/10/2008 Male 174 lb 6/12/2008 United States
Primary
Concomitant
Nightmare Other Serious 5/1/2008 72 Female 123 lb 6/16/2008 Physician United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 63 Male 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 63 Male 6/27/2008 United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/5/2008 70 Female 190 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Male 7/7/2008 Physician Germany
Primary
Concomitant
Rash Other Serious 6/11/2008 Female 192 lb 7/18/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Cyst Hospitalization 4/25/2008 Female 187 lb 7/21/2008 United Kingdom
Primary
Concomitant
Prostate Cancer Hospitalization 3/23/2005 76 Male 8/7/2008 United Kingdom
Primary
Secondary
Concomitant
Swelling Face 5/13/2008 Female 8/29/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 2/1/2008 83 Female 139 lb 8/29/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 4/1/2008 Male 9/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 12/1/2007 Female 201 lb 9/3/2008 Physician Germany
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 12/14/2005 Female 201 lb 9/30/2008 Physician United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/3/2008 United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 3/15/2006 Male 10/22/2008 Denmark
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/31/2008 United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/1/2008 56 Female 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 64 Female 11/7/2008 Netherlands
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2003 58 Female 12/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/14/2007 Female 172 lb 1/15/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 12/10/2008 70 Male 1/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization 12/3/2005 Male 159 lb 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/5/2009 United Kingdom
Primary
Secondary
Staphylococcal Sepsis Death Male 205 lb 2/9/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Hospitalization 71 Male 2/10/2009 Consumer Sweden
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/17/2009 Pharmacist United Kingdom
Primary
Secondary
Pain Disability 9/16/2008 Female 180 lb 2/18/2009 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/1/2006 2/27/2009 United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization NotSpecified 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Life Threatening 10/1/2008 45 Female 3/18/2009 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Osteomyelitis Other Serious 2/16/2009 Male 222 lb 4/1/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 12/1/2008 70 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Erectile Dysfunction 1/1/2009 82 Male 4/6/2009 Other Health Professional United States
Primary
Concomitant
Death Death Female 4/15/2009 Physician Slovenia
Primary
Secondary
Concomitant
Gynaecomastia Disability 1/5/2009 63 Male 4/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 3/2/2009 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 11/30/2008 Female 4/29/2009 Other Health Professional Portugal
Primary
Concomitant
Paternal Drugs Affecting Foetus 24 Female 4/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Erectile Dysfunction 1/1/2009 82 Male 5/7/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2008 Male 5/18/2009 Pharmacist Netherlands
Primary
Concomitant
Bronchial Disorder 75 Male 185 lb 6/23/2009 Consumer United States
Primary
Concomitant
Pneumonia Death Female 6/18/2009 Physician Germany
Primary
Concomitant
Vertigo Hospitalization 2/14/2009 Male 185 lb 6/24/2009
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 176 lb 6/29/2009 Physician United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/6/2009 Physician United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/7/2009 Physician United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/17/2009 Physician United Kingdom
Primary
Concomitant
Vertigo Hospitalization 2/14/2009 Male 185 lb 7/21/2009
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious 6/5/2009 67 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 4/1/2009 60 Female 7/24/2009 United States
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Female 8/3/2009 Consumer United States
Primary
Concomitant
Left Ventricular Failure Other Serious 6/23/2009 67 8/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/2/2008 83 Female 139 lb 8/7/2009 Physician United States
Primary
Concomitant
Ulcer Hospitalization 67 Male 7/30/2009 United States
Primary
Concomitant
Sudden Death Death Female 214 lb 8/14/2009 Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/8/2009 52 Female 8/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/8/2009 52 Female 8/17/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/8/2009 52 Female 119 lb 8/14/2009 United Kingdom
Primary
Secondary
Concomitant
Flushing 10/9/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/22/2009 United States
Primary
Concomitant
Nausea 5/1/2009 230 lb 8/22/2009 United States
Primary
Concomitant
Gout Other Serious 4/6/2009 53 Male 190 lb 9/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 4/6/2009 53 Male 9/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 4/6/2009 65 Female 9/9/2009 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 9/18/2009 Male 196 lb 10/15/2009 Germany
Primary
Concomitant
Staphylococcal Sepsis Death 6/1/2008 Male 205 lb 10/16/2009 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 9/18/2009 Male 196 lb 10/26/2009 Germany
Primary
Concomitant
Myopathy Disability 68 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 12/8/2008 70 Male 10/23/2009 United Kingdom
Primary
Concomitant
Swollen Tongue Hospitalization 6/1/2008 56 Female 10/23/2009 United Kingdom
Primary
Concomitant
Pain Other Serious 8/30/2008 60 Male 10/23/2009 United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 9/8/2009 53 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Hospitalization 9/2/2009 75 Female 130 lb 11/4/2009 Physician New Zealand
Primary
Concomitant
Ulcer Hospitalization 67 Male 11/4/2009 United States
Primary
Concomitant

Drug Data