Quetiapine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Mental Status Changes Other Serious 9/14/2005 44 Male 135 lb 2/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Psychotic Disorder Life Threatening 51 Female 196 lb 3/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Required Intervention 12/26/2005 81 Male 201 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 51 Female 3/20/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 9/14/2005 44 Male 135 lb 12/14/2005 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Persecutory Delusion Hospitalization 2/26/2006 38 Male 4/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Aspiration Death 52 Female 9/13/2006 Physician United States
Primary
Secondary
Ventricular Tachycardia Life Threatening 9/13/2006 45 Male 268 lb 9/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Repetitive Speech Other Serious 1/3/2007 80 Female 6/4/2007 Other Health Professional France
Primary
Concomitant
Pain Disability 5/7/2007 67 Male 7/7/2007 Physician United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/13/2007 75 Female 127 lb 12/3/2007 Physician Argentina
Primary
Concomitant
Drug Ineffective 12/15/2006 Male 155 lb 12/19/2007 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 10/13/2007 75 Female 127 lb 12/28/2007 Other Health Professional Argentina
Primary
Concomitant
Irritability Other Serious 10/13/2007 75 Female 127 lb 1/9/2008 Physician Argentina
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2007 85 Male 4/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 10/1/2006 Female 165 lb 4/29/2008 Consumer United States
Primary
Concomitant
Femur Fracture Other Serious 2/14/2008 88 Male 139 lb 8/27/2008 Australia
Primary
Concomitant
Pruritus Generalised 4/1/2008 Female 150 lb 8/27/2008 Consumer United States
Primary
Concomitant
Rhinorrhoea 5/16/2008 Male 8/27/2008 Other Health Professional United States
Primary
Concomitant
Femur Fracture Other Serious 2/14/2008 88 Male 139 lb 8/29/2008 Australia
Primary
Concomitant
Documented Hypersensitivity To Administered Drug Life Threatening 8/20/2008 51 Male 236 lb 9/13/2008 Pharmacist United States
Primary
Concomitant
Psychotic Disorder Hospitalization 85 Female 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 85 Female 3/31/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 1/23/2009 Female 216 lb 4/8/2009 Physician Austria
Primary
Concomitant
Mental Status Changes Required Intervention 2/24/2009 80 Male 207 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/14/2009 Male 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 5/14/2009 Male 6/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 3/1/2008 Male 220 lb 8/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization Female 8/26/2009 Consumer Australia
Primary
Secondary
Concomitant
Overdose Disability 38 Male 135 lb 9/1/2009 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Required Intervention 9/23/2009 60 Male 136 lb 10/5/2009 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Hospitalization 69 Female 11/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/10/2009 Male 12/8/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 69 Female 12/4/2009 Consumer
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 60 Female 12/10/2009 Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 11/10/2009 Male 12/30/2009 Physician United Kingdom
Primary
Concomitant
Hyperglycaemia Hospitalization 11/20/2009 74 Female 181 lb 1/6/2010 Physician Germany
Primary
Secondary
Respiratory Disorder Other Serious 69 Female 1/7/2010
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 69 Female 1/19/2010
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 9/10/2006 73 Female 2/4/2010 Physician New Zealand
Primary
Concomitant
Ear Pain Other Serious Female 2/15/2010 Pharmacist United Kingdom
Primary
Concomitant
Troponin Increased 4/13/2009 72 Male 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Troponin I Increased Other Serious 7/1/2009 65 Female 3/2/2010 United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Hypoaesthesia Oral Female 3/2/2010 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 6/1/2000 60 Female 3/29/2010
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/23/2010 64 Male 215 lb 4/3/2010 Pharmacist United States
Primary
Secondary
Renal Failure Acute Hospitalization 5/1/2009 69 Male 4/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/1/2008 68 Female 4/5/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Other Serious 5/12/2009 69 Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 5/12/2009 69 Male 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/12/2009 69 Male 4/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/12/2009 69 Male 4/19/2010
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/12/2009 69 Male 4/26/2010 Physician United Kingdom
Primary
Concomitant
Body Temperature Decreased Other Serious 5/12/2009 69 Male 198 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/13/2009 69 Male 4/30/2010
Primary
Concomitant
Somnolence Other Serious Male 5/25/2010 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/25/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 60 Female 6/4/2010 Australia
Primary
Secondary
Concomitant
Somnolence Other Serious Male 6/11/2010 Physician United Kingdom
Primary
Concomitant
Death Death 80 Female 6/25/2010 Physician United Kingdom
Primary
Concomitant
Hepatitis C Other Serious 4/1/2010 51 Male 7/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Cardiac Death Death 6/9/2010 79 Female 134 lb 7/16/2010 Physician United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 10/12/2009 47 Male 8/11/2010 Other Health Professional Germany
Primary
Concomitant
Tachycardia Hospitalization 55 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 69 Female 9/15/2010 Lawyer United States
Primary
Concomitant
Sudden Cardiac Death Death 6/9/2010 80 Female 134 lb 9/16/2010 Physician United Kingdom
Primary
Concomitant
Somnolence Hospitalization 8/4/2010 60 Female 10/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/4/2010 60 Female 10/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 69 Female 10/25/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 57 Male 250 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Stridor Life Threatening 10/24/2010 34 Male 309 lb 11/19/2010 Physician Denmark
Primary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/17/2010 73 Male 198 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Stridor Life Threatening 10/25/2010 34 Male 309 lb 11/30/2010 Physician Denmark
Primary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 6/9/2010 79 Female 134 lb 7/16/2010 Physician United Kingdom
Primary
Concomitant
Asthenia Other Serious Female 1/5/2011 Physician United Kingdom
Primary
Concomitant
Toxicity To Various Agents Death 62 Male 1/5/2011 Other Health Professional United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 62 Male 1/7/2011 Physician United States
Primary
Secondary
Asthenia Other Serious Female 1/17/2011 Physician United Kingdom
Primary
Concomitant
Death Death 62 Male 1/18/2011 Physician United States
Primary
Secondary
Fatigue Hospitalization 9/19/2010 82 Male 145 lb 1/21/2011 Physician United States
Primary
Concomitant
Lip Swelling Hospitalization 12/5/2010 89 Female 134 lb 1/27/2011 Pharmacist United States
Primary
Concomitant
Poisoning Death 1/1/2009 62 Male 1/27/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 62 Male 1/25/2011 Physician United States
Primary
Secondary
Paraesthesia Other Serious 9/19/2010 82 Male 145 lb 2/22/2011 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2010 63 Female 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 10/1/2000 55 Male 3/1/2011 Lawyer United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 62 Male 3/6/2011 Other Health Professional United States
Primary
Secondary
Death Hospitalization 62 Male 2/24/2011 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Death 62 3/11/2011 Physician United States
Primary
Secondary
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant
Dependence Other Serious 10/1/2000 55 Male 3/15/2011 Lawyer United Kingdom
Primary
Concomitant
Potentiating Drug Interaction Hospitalization 5/14/2009 Male 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Death 62 Male 3/24/2011 Physician United States
Primary
Secondary
Neutropenia Death 3/19/2011 63 Male 3/23/2011 Pharmacist United States
Primary
Concomitant
Death Other Serious 1/1/2011 63 Male 4/4/2011 Pharmacist United States
Primary
Concomitant
Mania Hospitalization 1/31/2011 72 Female 4/6/2011 Physician Austria
Primary
Concomitant
Blood Creatinine Increased Death 2/21/2011 87 Male 193 lb 4/13/2011 Pharmacist United States
Primary
Secondary
Concomitant
Mania Hospitalization 1/31/2011 72 Female 4/27/2011 Consumer Austria
Primary
Concomitant
Condition Aggravated Other Serious 3/10/2011 35 Female 5/6/2011 Physician United Kingdom
Primary
Concomitant
Back Pain Hospitalization 3/1/2000 39 Male 5/9/2011 Physician United States
Primary
Concomitant
Product Contamination Death 2/21/2011 87 Male 193 lb 4/12/2011 Pharmacist United States
Primary
Concomitant
Rash Required Intervention 3/28/2011 39 Female 196 lb 3/28/2011 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/2011 51 Male 6/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Ischaemic Stroke Death 9/17/2010 76 Female 6/23/2011 Consumer Brazil
Primary
Secondary
Concomitant
Nephropathy Hospitalization 7/10/2010 67 Male 7/1/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Blood Creatinine Increased Death 2/21/2011 87 Male 193 lb 7/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Death 2/21/2011 87 Male 193 lb 7/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 7/18/2011 68 Male 8/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Fear Other Serious 79 Female 8/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 60 9/23/2011 Other Health Professional United States
Primary
Secondary
Off Label Use 5/2/2006 71 Male 9/23/2011 Physician Canada
Primary
Secondary
Concomitant
Fluid Retention Hospitalization 43 Male 288 lb 10/4/2011 Lawyer United States
Primary
Concomitant
Hypertension Hospitalization 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Hypertension Hospitalization 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Concomitant
Drug Ineffective Other Serious 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 49 Male 10/14/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Eosinophil Count Increased Hospitalization 9/1/2011 64 Female 10/25/2011 Physician Finland
Primary
Concomitant
Cerebrovascular Accident Other Serious 83 Male 11/4/2011 Consumer Germany
Primary
Concomitant
Lacunar Infarction Hospitalization 50 Male 11/14/2011 Physician Netherlands
Primary
Secondary
Concomitant
Periorbital Oedema Hospitalization 50 Male 11/14/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/13/2011 52 Male 11/17/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/13/2011 52 Male 298 lb 11/23/2011 Consumer United States
Primary
Concomitant
Chest Discomfort Disability 12/1/2010 71 Male 251 lb 11/28/2011 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious 49 Male 11/30/2011 Physician Netherlands
Primary
Secondary
Concomitant
Periorbital Oedema Other Serious 49 Male 12/23/2011 Netherlands
Primary
Secondary
Concomitant
Hypertension Other Serious 49 Male 12/23/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 49 Male 12/23/2011 Netherlands
Primary
Secondary
Concomitant
Cellulitis Other Serious 75 Male 1/3/2012 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/9/2011 69 Female 1/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 10/25/2010 37 Male 309 lb 1/19/2012 Physician Denmark
Primary
Concomitant
Death Death 10/10/2011 88 Male 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dysarthria Hospitalization 10/1/2003 55 Male 185 lb 1/30/2012 Lawyer United States
Primary
Concomitant
Lethargy Hospitalization 8/4/2010 60 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 8/4/2010 60 Female 10/8/2010 United Kingdom
Primary
Secondary
Concomitant
Salmonellosis Hospitalization Male 2/15/2012 Pharmacist Australia
Primary
Concomitant
Drug Interaction Other Serious 59 Male 3/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Drug Interaction Other Serious 62 Female 4/6/2012 Physician Austria
Primary
Interacting
Syncope Hospitalization 5/8/2012 57 Male 187 lb 5/9/2012 Pharmacist United States
Primary
Secondary
Drug Interaction Hospitalization 8/20/2011 71 Male 5/22/2012 Physician Spain
Primary
Concomitant
Interacting

Drug Data