Enalapril combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Tachycardia Death 11/17/2005 77 Female 1/3/2006 Other Health Professional Netherlands
Primary
Concomitant
Fatigue Other Serious 11/1/2005 75 Female 1/4/2006 Consumer United Kingdom
Primary
Concomitant
Electrocardiogram Pr Prolongation Other Serious 75 Male 1/12/2006 Italy
Primary
Concomitant
Rectal Haemorrhage Required Intervention 9/6/2005 50 Male 194 lb 1/3/2006 United States
Primary
Concomitant
Heart Rate Decreased Other Serious 75 Male 1/23/2006 Other Health Professional Italy
Primary
Concomitant
Nephropathy Toxic Required Intervention 7/28/2005 66 Male 157 lb 10/25/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 9/23/2005 72 Male 176 lb 1/30/2006 Physician
Primary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Post Procedural Complication Life Threatening 10/1/2005 Male 177 lb 1/31/2006 Pharmacist Germany
Primary
Concomitant
Electrocardiogram T Wave Inversion Death 10/9/2005 67 Male 211 lb 2/2/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 74 Male 249 lb 2/7/2006 Physician United Kingdom
Primary
Concomitant
Haematocrit Decreased Hospitalization 12/28/2005 62 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/29/2005 78 Male 188 lb 1/10/2006 Pharmacist United States
Primary
Concomitant
Mouth Ulceration Other Serious 12/10/2005 76 Male 2/22/2006 Consumer United Kingdom
Primary
Concomitant
Syncope Other Serious 1/1/2005 75 Male 5/17/2006 Physician Italy
Primary
Concomitant
Acute Myocardial Infarction Death 4/28/2006 62 Female 5/30/2006 Physician Sweden
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/26/2005 60 Male 5/24/2006 Brazil
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 2/21/2005 68 Male 154 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cardiopulmonary Failure Hospitalization 1/26/2005 Female 6/16/2006 Physician Spain
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2006 70 Male 6/19/2006 Physician Spain
Primary
Secondary
Concomitant
Erectile Dysfunction 82 Male 4/25/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/15/2005 84 Female 66 lb 6/19/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/5/2005 58 Male 201 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/14/2004 72 Male 170 lb 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 73 Male 6/29/2006 Other Health Professional Australia
Primary
Concomitant
Chest Pain Hospitalization 4/10/2004 69 Female 7/6/2006 Consumer Italy
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 8/11/2006 Canada
Primary
Concomitant
Neurotoxicity Required Intervention 77 Female 8/18/2006 Physician New Zealand
Primary
Concomitant
Renal Failure Hospitalization 6/29/2006 49 Male 190 lb 8/25/2006 Physician Spain
Primary
Concomitant
Rhabdomyolysis Other Serious 9/14/2004 72 Male 170 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2004 72 Male 170 lb 8/22/2006 Physician United States
Primary
Secondary
Concomitant
Soft Tissue Necrosis Other Serious 1/1/2006 Female 157 lb 9/6/2006 Physician Germany
Primary
Secondary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Paraesthesia Death 1/1/2006 Female 157 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Calcification Hospitalization 8/2/2006 Female 165 lb 9/11/2006 Other Health Professional Romania
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/22/2006 68 Male 9/11/2006 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 56 Male 9/25/2006 Consumer United States
Primary
Concomitant
Soft Tissue Necrosis Other Serious 1/1/2006 Female 157 lb 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Dysgeusia 11/18/2006 63 Female 145 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 5/1/2007
Primary
Concomitant
Suicidal Ideation Life Threatening 4/1/2007 65 Male 5/9/2007 Consumer United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 2/24/2007 46 Male 159 lb 5/11/2007 Consumer Brazil
Primary
Concomitant
Speech Disorder Hospitalization 2/24/2007 46 Male 159 lb 5/12/2007 Consumer Brazil
Primary
Concomitant
Nephrotic Syndrome Other Serious 2/20/2007 Male 5/15/2007 Physician Germany
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/30/2007 Female 198 lb 5/21/2007 Physician Australia
Primary
Concomitant
Speech Disorder Hospitalization 2/24/2007 46 Male 159 lb 5/22/2007 Consumer Brazil
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/30/2007 Female 198 lb 5/23/2007 Physician Australia
Primary
Concomitant
Fluid Overload Other Serious 2/2/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2006 Male 141 lb 5/24/2007 Austria
Primary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Fall Hospitalization 7/1/2006 60 Female 6/13/2007
Primary
Concomitant
Neutropenic Sepsis Hospitalization 4/23/2007 69 Female 137 lb 6/16/2007 United Kingdom
Primary
Secondary
Concomitant
Wheezing Life Threatening 8/11/2004 Male 7/9/2007 Physician United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 2/7/2007 Male 8/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 6/8/2007 75 Female 8/23/2007
Primary
Secondary
Urinary Bladder Haemorrhage Other Serious 3/12/2007 77 Male 9/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracardiac Thrombus Life Threatening 8/19/2007 58 Male 11/27/2007 Consumer Denmark
Primary
Concomitant
Hyperglycaemia Other Serious 54 Male 165 lb 11/30/2007 Consumer Brazil
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 10/11/2007 Male 145 lb 10/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Other Serious 10/5/2007 54 Male 11/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 10/31/2007 Male 12/5/2007 Germany
Primary
Concomitant
Thrombocytopenia Other Serious 2/5/2007 Male 187 lb 12/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 3/6/2007 49 Male 146 lb 12/6/2007 Physician Spain
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/13/2007 75 Female 127 lb 12/3/2007 Physician Argentina
Primary
Concomitant
Dysarthria Hospitalization 73 Male 12/3/2007 Other Health Professional Sweden
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 72 Male 176 lb 11/14/2007 Israel
Primary
Concomitant
Vertigo Death 10/12/2007 84 Female 12/11/2007 Germany
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 72 Male 176 lb 12/20/2007 Israel
Primary
Concomitant
Drug Ineffective 9/1/2006 82 Male 12/20/2007 Consumer United States
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 5/15/2007 Male 192 lb 12/21/2007 Consumer Sweden
Primary
Secondary
Concomitant
Resorption Bone Increased Other Serious 4/2/2007 77 Male 187 lb 12/28/2007 Pharmacist Germany
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 72 Male 176 lb 12/31/2007 Israel
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 3/22/2007 Male 192 lb 1/3/2008 Consumer Sweden
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 7/10/2007 51 Female 1/4/2008 Physician Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/1/2007 80 Male 1/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/10/2007 63 Male 290 lb 1/8/2008 Consumer United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/3/2007 66 Male 185 lb 12/6/2007 Pharmacist United States
Primary
Concomitant
Femoral Artery Occlusion Hospitalization 10/1/2007 67 Female 1/18/2008 Germany
Primary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 1/30/2008 Physician Australia
Primary
Concomitant
Pain In Extremity 76 Male 174 lb 8/18/2008 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 4/10/2008 57 Female 190 lb 9/9/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 12/12/2008 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/22/2009 Consumer Austria
Primary
Concomitant
Renal Impairment Hospitalization 12/21/2008 82 Male 1/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 2/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intentional Drug Misuse Other Serious 1/1/2009 2/11/2009 Physician Brazil
Primary
Secondary
Concomitant
Pain Other Serious 8/22/2008 Female 170 lb 2/11/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Death 11/12/2008 Male 200 lb 2/11/2009 Consumer United States
Primary
Secondary
Concomitant
Pericarditis Constrictive Life Threatening 4/1/2008 68 Female 2/16/2009 Consumer Netherlands
Primary
Concomitant
Oesophageal Candidiasis Other Serious 2/16/2009 Consumer Brazil
Primary
Concomitant
Pericarditis Constrictive Life Threatening 4/1/2008 68 Female 2/23/2009 Consumer Netherlands
Primary
Concomitant
Diarrhoea Male 2/24/2009 United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/6/2009 Female 132 lb 2/26/2009 Physician Brazil
Primary
Concomitant
Glossodynia Hospitalization 5/31/2008 Male 2/26/2009 Physician Germany
Primary
Concomitant
Sepsis Life Threatening 12/27/2008 67 Male 154 lb 3/2/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2008 50 Female 139 lb 3/3/2009 Consumer Brazil
Primary
Secondary
Concomitant
Myoglobin Urine Present Hospitalization 68 Female 2/25/2009 Physician Brazil
Primary
Concomitant
Vomiting Hospitalization 60 Male 3/4/2009 Other Health Professional Brazil
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 50 Female 139 lb 3/5/2009 Consumer Brazil
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 9/22/2008 74 Male 276 lb 3/11/2009 Physician Germany
Primary
Concomitant
Interacting
Bipolar I Disorder Other Serious 2/1/2009 Female 3/10/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 9/22/2008 74 Male 276 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Oedema Mucosal Other Serious 62 Female 3/12/2009 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Nystagmus Hospitalization 5/19/2008 67 Male 230 lb 3/13/2009 Other Health Professional Sweden
Primary
Concomitant
Shock Hospitalization 2/9/2007 Female 154 lb 3/5/2009 Other Health Professional Germany
Primary
Concomitant
Oedema Peripheral 12/5/2008 69 Female 168 lb 3/16/2009 Consumer United States
Primary
Concomitant
Flushing 1/26/2009 Male 167 lb 3/16/2009 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 5/19/2008 67 Male 230 lb 3/12/2009 Other Health Professional Sweden
Primary
Concomitant
Vasodilatation Hospitalization 5/26/2006 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/27/2008 67 Male 154 lb 3/19/2009 Physician Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/26/2008 Male 3/23/2009 Physician Germany
Primary
Concomitant
Somnolence Other Serious 2/1/2009 Female 529 lb 3/23/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 3/26/2009 Physician United States
Primary
Concomitant
Overdose Other Serious 10/15/2008 3/26/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Uraemic Encephalopathy Hospitalization 2/24/2009 65 Female 3/25/2009 Pharmacist United States
Primary
Concomitant
Confusional State Life Threatening 2/26/2009 49 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Life Threatening 2/26/2009 49 Male 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 4/1/2009 Physician United States
Primary
Concomitant
Pyrexia Death 55 Female 4/1/2009 Physician Finland
Primary
Concomitant
Overdose Other Serious 10/15/2008 Male 4/2/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 4/3/2009 United States
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Red Blood Cell Sedimentation Rate Increased Other Serious 2/1/2009 Female 4/8/2009 Sweden
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2009 Female 4/9/2009 Physician Austria
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 78 Male 4/3/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/26/2008 Male 4/10/2009 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 4/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/11/2009 61 Male 4/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2009 Female 529 lb 4/14/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 62 Female 4/15/2009
Primary
Secondary
Concomitant
Gastritis Other Serious 62 Female 4/16/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2009 Female 4/17/2009 Physician Austria
Primary
Secondary
Concomitant
Pyrexia Death 55 Female 4/17/2009 Consumer Finland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/1/2009 69 Female 229 lb 4/17/2009 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 69 Female 229 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Male 4/21/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 80 Male 176 lb 4/22/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Overdose Other Serious 10/15/2008 Male 4/22/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/15/2007 Male 234 lb 4/22/2009 Physician Sweden
Primary
Secondary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/7/2009 4/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/27/2008 4/24/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant

Drug Data