Bisoprolol Fumarate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toe Amputation Hospitalization 10/1/2005 73 Male 1/12/2006 Physician Netherlands
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 76 Male 1/10/2006 France
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 3/14/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/21/2005 56 Male 236 lb 3/27/2006 Other Health Professional Germany
Primary
Concomitant
Parkinsonism Disability 1/1/2004 Female 4/14/2006 Pharmacist France
Primary
Concomitant
Interacting
Parkinsonism Disability 1/1/2004 65 Female 4/10/2006 Pharmacist Ireland
Primary
Concomitant
Tremor Disability 1/1/2004 65 Female 5/3/2006 Other Health Professional Denmark
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 9/3/2005 46 Male 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/17/2006 Physician Austria
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/1/2006 64 Male 214 lb 5/26/2006 Physician Germany
Primary
Concomitant
Sleep Disorder Hospitalization 4/21/2006 63 Male 176 lb 6/1/2006 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Other Serious 11/3/2005 74 Female 98 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Wheezing Hospitalization 5/8/2006 76 Male 6/9/2006 United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious Female 132 lb 6/22/2006 Physician Germany
Primary
Concomitant
Urinary Casts Other Serious 12/1/2004 63 Female 7/10/2006 Other Health Professional Germany
Primary
Concomitant
Intracranial Pressure Increased Life Threatening 10/1/2005 64 Male 7/10/2006 Norway
Primary
Secondary
Concomitant
Angioneurotic Oedema Other Serious 74 Male 7/13/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/8/2006 42 Male 220 lb 7/14/2006 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/2/2006 76 Male 7/19/2006 Physician Italy
Primary
Concomitant
Cerebral Infarction Hospitalization 3/1/2006 57 Male 7/28/2006 Consumer Sweden
Primary
Secondary
Concomitant
Oesophagitis Other Serious 56 Male 7/24/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 3/1/2000 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 4/8/2006 42 Male 220 lb 7/27/2006 Netherlands
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 5/1/2006 60 Male 8/3/2006 Other Health Professional France
Primary
Concomitant
Intracranial Pressure Increased Life Threatening 10/1/2005 64 Male 7/27/2006 Norway
Primary
Secondary
Concomitant
Thrombosis Other Serious 66 Male 7/28/2006 Pharmacist Germany
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 1/1/2005 52 Female 220 lb 8/11/2006 Physician Germany
Primary
Secondary
Concomitant
Photosensitivity Reaction Hospitalization 5/18/2006 71 Male 8/10/2006 France
Primary
Secondary
Concomitant
Glaucoma Hospitalization 12/7/2005 72 Female 7/31/2006 Poland
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Epistaxis Other Serious 2/8/2006 45 Male 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/9/2006 73 Male 187 lb 8/31/2006 Germany
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Disability 1/4/2005 8/31/2006 Singapore
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 8/29/2006 Thailand
Primary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Visual Acuity Reduced Life Threatening 1/10/2006 Female 146 lb 9/7/2006 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 3/28/2006 73 Male 165 lb 9/1/2006 Physician Germany
Primary
Concomitant
Vasculitis Other Serious 11/15/2005 Female 111 lb 9/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Yellow Skin Hospitalization 8/27/2006 69 Male 9/8/2006 Physician Austria
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 8/30/2006 Thailand
Primary
Concomitant
Vomiting Hospitalization 4/21/2005 56 Male 236 lb 9/18/2006
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 9/8/2006 Thailand
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 9/8/2006 Thailand
Primary
Concomitant
Vomiting Hospitalization 7/24/2006 73 Male 187 lb 9/19/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/28/2006 64 Female 143 lb 9/27/2006 Physician Germany
Primary
Concomitant
Lethargy Other Serious 8/3/2006 72 Male 172 lb 9/28/2006 Consumer United Kingdom
Primary
Concomitant
Yellow Skin Hospitalization 8/27/2006 69 Male 9/28/2006 Physician Austria
Primary
Concomitant
Yersinia Infection Hospitalization 7/24/2006 73 Male 187 lb 9/30/2006 Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Peritonitis Hospitalization 5/4/2006 72 Female 10/5/2006 United Kingdom
Primary
Concomitant
Panic Attack Hospitalization 9/3/2006 63 Male 258 lb 10/5/2006 Germany
Primary
Concomitant
Panic Attack Hospitalization 8/15/2006 63 Male 258 lb 10/5/2006 Other Health Professional Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 10/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/16/2006 Physician
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 4/3/2005 52 Female 322 lb 10/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2006 76 Female 10/11/2006 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 6/23/2005 77 Male 185 lb 10/13/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 201 lb 10/14/2006 United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/23/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 68 Female 10/26/2006 Pharmacist Germany
Primary
Secondary
Coronary Artery Disease Hospitalization 6/27/2005 42 Male 176 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Death 10/16/2006 73 Male 11/6/2006 Physician Netherlands
Primary
Secondary
Concomitant
Suicidal Ideation Life Threatening 68 Female 11/7/2006 Pharmacist Germany
Primary
Secondary
Coronary Ostial Stenosis Hospitalization 7/1/2006 62 Male 11/8/2006 Physician Sweden
Primary
Concomitant
Nicotine Dependence Life Threatening Female 10/31/2006 Consumer United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tibia Fracture Hospitalization 7/17/2006 81 Female 117 lb 11/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapy Cessation Hospitalization 10/19/2006 67 Male 122 lb 11/3/2006 Physician United Kingdom
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 11/17/2006 Physician Germany
Primary
Concomitant
Syncope Other Serious 84 Female 126 lb 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 11/22/2006 Physician Germany
Primary
Concomitant
Septic Shock Hospitalization 1/1/2005 Female 11/22/2006 Physician Spain
Primary
Concomitant
Hypoaesthesia Oral Hospitalization Female 98 lb 11/22/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Life Threatening 63 Female 11/13/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Death 10/14/2006 69 Female 11/27/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stomatitis Hospitalization 10/18/2006 67 Male 122 lb 12/4/2006 Physician United Kingdom
Primary
Concomitant
Thyrotoxic Crisis Life Threatening 5/1/2003 65 Male 12/4/2006 Germany
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 11/4/2005 72 Female 165 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Death 80 Male 187 lb 12/15/2006 Physician Germany
Primary
Concomitant
Suicidal Ideation Life Threatening 68 Female 12/29/2006 Pharmacist Germany
Primary
Secondary
Weight Decreased Life Threatening 5/1/2003 65 Male 12/21/2006 Germany
Primary
Concomitant
Exercise Tolerance Decreased Other Serious 10/30/2006 77 Female 12/20/2006 United Kingdom
Primary
Concomitant
Suicidal Ideation Life Threatening 12/22/2006 United Kingdom
Primary
Concomitant
Pruritus Other Serious 1/1/2002 69 Male 1/6/2007 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 1/3/2007 Physician Austria
Primary
Concomitant
No Adverse Drug Effect Hospitalization 11/28/2005 54 Male 159 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 6/27/2005 42 Male 176 lb 1/5/2007 Poland
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/31/2005 60 Male 165 lb 1/5/2007 Poland
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 1/11/2007 Physician Germany
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 11/7/2006 78 Male 1/11/2007 France
Primary
Secondary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/9/2006 73 Male 183 lb 1/19/2007 Physician Germany
Primary
Concomitant
Toe Amputation Hospitalization 10/1/2005 73 Male 1/16/2007 Netherlands
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Restlessness Other Serious 11/29/2006 57 Male 1/30/2007 Physician Belgium
Primary
Concomitant
Stomatitis Hospitalization 10/18/2006 Male 122 lb 2/1/2007 United Kingdom
Primary
Concomitant
Sepsis Other Serious 4/1/2005 66 Male 2/1/2007 Singapore
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 1/14/2007 80 Male 2/8/2007 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 4/21/2006 Male 176 lb 2/14/2007 Germany
Primary
Concomitant
Pruritus Other Serious 1/1/2002 69 Male 2/17/2007 Physician United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 12/31/2005 60 Male 165 lb 2/12/2007 Poland
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 91 Male 2/26/2007 United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 10/15/2005 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Myositis Life Threatening 6/1/2006 75 Male 139 lb 3/1/2007 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/1/2007 United Kingdom
Primary
Concomitant
Sepsis Other Serious 4/1/2005 66 Male 3/1/2007 Singapore
Primary
Concomitant
Pain In Extremity Other Serious 11/3/2006 72 Male 209 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 3/24/2007 75 Male 4/25/2007 United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 75 Male 4/26/2007 United Kingdom
Primary
Concomitant
Sepsis Other Serious 4/1/2005 76 Male 4/27/2007 Singapore
Primary
Concomitant
Linear Iga Disease Life Threatening 1/23/2007 79 Female 110 lb 4/28/2007 United Kingdom
Primary
Concomitant
Mood Swings Other Serious 1/1/2005 39 Male 5/2/2007 United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 3/7/2007 72 Male 5/11/2007 Physician United Kingdom
Primary
Concomitant
Pain Disability 2/14/2007 Male 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mood Swings Other Serious 1/1/2005 39 Male 5/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Relapsing Hospitalization 4/21/2007 71 Male 229 lb 5/15/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Linear Iga Disease Life Threatening 1/23/2007 79 Female 110 lb 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 3/14/2007 Male 198 lb 5/16/2007 Physician
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 3/3/2007 Male 5/10/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/1/2006 71 Male 229 lb 5/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Other Serious Male 5/21/2007 Physician Germany
Primary
Concomitant
Interacting
Sinoatrial Block Other Serious 3/23/2007 47 Male 5/14/2007 Spain
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 7/13/2006 Male 159 lb 5/25/2007 United Kingdom
Primary
Concomitant
Skull Fracture Hospitalization 12/1/2006 73 Male 5/29/2007 Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 6/1/2006 71 Male 229 lb 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2006 71 Male 229 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 64 Male 207 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 1/1/2006 64 Male 5/31/2007 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 5/27/2007 60 Male 6/7/2007 Physician Germany
Primary
Concomitant
Syncope Life Threatening 1/1/2006 64 Male 207 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2007 67 Male 251 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/4/2006 Female 198 lb 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data