Acetaminophen combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vertigo Other Serious 9/30/2005 50 Male 1/6/2006 France
Primary
Secondary
Colorectal Cancer Hospitalization 11/5/2004 63 Male 1/9/2006 United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 11/12/2005 59 Male 174 lb 1/17/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Other Serious 79 Male 156 lb 1/20/2006 Physician Canada
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Agranulocytosis Hospitalization 11/20/2005 70 Female 150 lb 1/23/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Drug Ineffective Other Serious 8/1/2005 67 Female 1/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 66 Male 180 lb 1/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arrhythmia Required Intervention 10/31/2005 58 Male 269 lb 10/31/2005 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/1/2005 82 Male 172 lb 11/1/2005 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 12/14/2005 86 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/22/2005 72 Female 99 lb 2/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 2/13/2006 Physician Ireland
Primary
Concomitant
Interacting
Radiculopathy Hospitalization 11/1/2003 Male 231 lb 2/15/2006 Physician New Zealand
Primary
Concomitant
Post Procedural Complication Hospitalization 5/28/2005 68 Female 2/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 5/24/2005 Female 115 lb 2/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 154 lb 2/23/2006 Physician Ireland
Primary
Concomitant
Interacting
Sedation Hospitalization 2/19/2005 Female 2/24/2006 Consumer Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Spinal Cord Compression Disability 12/5/2005 73 Female 2/23/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/1/2005 81 Female 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 1/31/2006 81 Male 3/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/7/2006 United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/6/2006 85 Male 137 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pharyngeal Oedema Other Serious 5/27/2005 59 Male 3/27/2006 Consumer Spain
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Gait Disturbance 1/18/2006 61 Male 4/7/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 7/26/2005 67 Male 161 lb 2/14/2006 Physician Italy
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Vomiting Other Serious 9/26/2005 71 Female 182 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Surgery Hospitalization 1/1/2002 67 Male 176 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Surgery Hospitalization 1/1/2002 65 Male 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Haemorrhage Hospitalization 1/5/2006 67 Male 191 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 8/24/2005 85 Male 5/12/2006 Other Health Professional Australia
Primary
Concomitant
International Normalised Ratio Increased Disability 3/28/2006 61 Female 5/10/2006 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 3/7/2006 57 Male 320 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 4/14/2006 76 Male 218 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Muscle Haemorrhage Hospitalization 10/1/2004 74 Female 123 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stem Cell Transplant Death 2/1/2004 50 Male 5/25/2006 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 10/12/2005 57 Female 6/5/2006 Physician Netherlands
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2006 77 Male 5/5/2006 Consumer United States
Primary
Concomitant
Fall Hospitalization 5/22/2006 85 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 11/5/2004 57 Male 256 lb 7/5/2006 Physician Denmark
Primary
Concomitant
Dry Mouth Other Serious 6/21/2006 56 Male 277 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Hypotension Other Serious 5/8/2006 80 Male 166 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Angina Pectoris Hospitalization 8/25/2004 58 Female 150 lb 7/19/2006 Physician Denmark
Primary
Concomitant
Renal Failure Acute Hospitalization 5/22/2006 78 Female 7/20/2006 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/18/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Joint Swelling Disability 7/6/2006 62 Male 7/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 56 Female 5/16/2006 United States
Primary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 7/28/2006 Physician Germany
Primary
Concomitant
Vasculitis Other Serious 6/21/2006 77 Female 8/1/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 75 Male 128 lb 8/1/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/27/2006 Denmark
Primary
Secondary
Concomitant
Vasculitis Other Serious 6/21/2006 77 Female 7/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/7/2006 Physician United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization 11/5/2004 57 Male 256 lb 8/9/2006 Physician Denmark
Primary
Concomitant
Visual Acuity Reduced Disability 3/25/2002 78 Female 103 lb 8/15/2006 Physician United Kingdom
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 8/16/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 8/10/2006 Netherlands
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/18/2006 Physician United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 61 Male 8/14/2006 Denmark
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 8/25/2004 58 Female 150 lb 8/22/2006 Physician Denmark
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Fatigue Hospitalization 72 Male 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/12/2006 56 Male 162 lb 6/12/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/10/2005 85 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Myalgia Hospitalization Female 9/1/2006 Pharmacist United Kingdom
Primary
Concomitant
Vasculitis Hospitalization 12/15/2005 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Helicobacter Infection Hospitalization 1/10/2005 85 Female 8/28/2006 United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 9/16/2005 76 Male 134 lb 8/31/2006 United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 9/8/2006 Netherlands
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 9/12/2006 68 Male 173 lb 9/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Abdominal Discomfort Other Serious 7/10/2006 78 Male 180 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 6/28/2006 80 Male 108 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/9/2006 50 Male 9/27/2006 United Kingdom
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2006 74 Male 10/5/2006
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 6/1/2006 Female 10/5/2006 Pharmacist United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 3/25/2006 66 Male 231 lb 10/2/2006 United Kingdom
Primary
Secondary
Concomitant
Procedural Pain Hospitalization 8/21/2006 57 Male 176 lb 10/5/2006 Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 3/25/2006 66 Male 231 lb 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 56 Male 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 8/23/2006 85 Male 160 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 7/16/2006 49 Male 176 lb 10/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Rash Disability 7/6/2006 Male 282 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 10/30/2006 Physician Germany
Primary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 10/4/2006 84 Male 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Tachycardia Life Threatening 9/6/2006 79 Male 197 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 68 Female 11/8/2006 Other Health Professional Lebanon
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Coronary Ostial Stenosis Hospitalization 7/1/2006 62 Male 11/8/2006 Physician Sweden
Primary
Concomitant
Neoplasm Malignant Other Serious Female 205 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 80 Male 126 lb 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/10/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Myocardial Infarction Other Serious 10/25/2006 58 Male 190 lb 11/13/2006
Primary
Concomitant
Rash Erythematous Other Serious 10/6/2006 62 Female 198 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 11/7/2006 Male 203 lb 11/9/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/6/2006 74 Female 11/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rash Erythematous Disability 10/6/2006 62 Female 198 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Required Intervention 8/2/2006 25 Male 198 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 9/15/2006 61 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Disability 7/24/2006 73 Female 11/13/2006 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Pruritus Other Serious 8/13/2006 70 Male 218 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Other Serious 7/15/2006 87 Male 191 lb 8/15/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Radius Fracture Hospitalization 10/25/2006 80 Male 12/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Reaction Other Serious 10/6/2006 62 Female 198 lb 11/27/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Other Serious 11/1/2004 65 Female 12/7/2006 Pharmacist Australia
Primary
Concomitant
Multi-organ Failure Other Serious 10/30/2004 Male 254 lb 12/8/2006 Physician United Kingdom
Primary
Concomitant
Wound Secretion Other Serious 10/23/2006 67 Female 12/12/2006 Other Health Professional Australia
Primary
Concomitant
Vomiting Hospitalization 5/6/2006 74 Female 12/4/2006 United States
Primary
Secondary
Concomitant
Infusion Site Reaction Hospitalization 10/1/2006 70 Male 187 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant
Hidradenitis Hospitalization 68 Female 12/15/2006 Other Health Professional Lebanon
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 10/26/2006 47 Male 110 lb 12/7/2006 United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 2/1/2005 66 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Hospitalization 66 Male 12/14/2006 Physician Switzerland
Primary
Concomitant
Convulsion Hospitalization 12/5/2006 79 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant

Drug Data