Propofol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nosocomial Infection Other Serious 10/6/2003 Male 240 lb 2/20/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Pleurisy Life Threatening 1/10/2005 73 Female 174 lb 5/23/2006 Physician France
Primary
Secondary
Concomitant
Pleurisy Life Threatening 1/10/2005 73 Female 174 lb 6/13/2006 Physician France
Primary
Secondary
Concomitant
Urticaria Other Serious 8/26/2005 76 Male 176 lb 7/17/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/28/2006 64 Female 143 lb 9/27/2006 Physician Germany
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urticaria Other Serious 8/26/2005 76 Male 176 lb 11/15/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Wound Secretion Other Serious 10/23/2006 67 Female 12/12/2006 Other Health Professional Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 5/19/2006 40 Male 203 lb 3/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 10/25/2006 67 Female 3/29/2007 Other Health Professional Australia
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 5/19/2006 40 Male 203 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest 2/20/2007 62 Female 3/23/2007 United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 2/20/2007 62 Female 3/27/2007 United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 2/20/2007 62 Female 143 lb 4/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Test Positive Hospitalization 12/8/2006 83 Female 4/6/2007 France
Primary
Concomitant
Wound Secretion Hospitalization 10/25/2006 67 Female 4/30/2007 Other Health Professional Australia
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Somnolence Hospitalization 65 Female 254 lb 4/28/2007 Consumer United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Tachycardia Death 6/6/2007 65 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 6/1/2007 72 Female 10/23/2007 Physician France
Primary
Concomitant
Weight Decreased Other Serious 66 Male 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myopathy Toxic Death 66 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 64 Male 12/7/2007 Canada
Primary
Secondary
Concomitant
Septic Shock Death 66 Male 12/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 66 Male 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Myopathy Toxic Other Serious 66 Male 12/31/2007 United States
Primary
Secondary
Ventricular Tachycardia Death 10/14/2007 37 Female 146 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 1/8/2008 Physician United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 58 Female 1/29/2008 Physician New Zealand
Primary
Secondary
Concomitant
Respiratory Failure Death 76 Female 104 lb 2/11/2008 Physician New Zealand
Primary
Concomitant
Serotonin Syndrome Other Serious 58 Female 2/12/2008 New Zealand
Primary
Secondary
Concomitant
Tachycardia Other Serious 58 Female 2/20/2008 New Zealand
Primary
Concomitant
Rhabdomyolysis Death 66 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 10/1/2007 64 Male 2/22/2008 Physician Canada
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 65 Female 254 lb 3/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 1/1/2008 66 Male 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Coagulation Factor Increased Hospitalization 9/18/2007 79 Female 5/15/2008 Other Health Professional Sweden
Primary
Concomitant
Coagulation Factor Increased Hospitalization 9/18/2007 79 Female 5/23/2008 Other Health Professional Sweden
Primary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 5/19/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 66 Male 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 76 Female 7/3/2008 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 65 Female 7/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulse Absent Life Threatening 2/22/2008 Male 205 lb 7/18/2008 Consumer Australia
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 65 Female 7/28/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 3/30/2008 80 Male 7/23/2008 New Zealand
Primary
Concomitant
Serotonin Syndrome Other Serious 65 Female 7/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 65 Female 8/15/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/30/2008 80 Male 8/14/2008 New Zealand
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Staring Hospitalization 44 Female 11/21/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sluggishness Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 44 Female 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 44 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 44 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 44 Female 12/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 12/11/2008 United Kingdom
Primary
Secondary
Concomitant
Staring Other Serious 44 Female 12/12/2008 United Kingdom
Primary
Secondary
Concomitant
Wernicke-korsakoff Syndrome Hospitalization 11/13/2008 69 Male 160 lb 12/13/2008 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Other Serious 12/18/2007 57 Female 152 lb 1/9/2009 Pharmacist United States
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 1/12/2009
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 11/3/2008 44 Female 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 44 Female 1/27/2009 United Kingdom
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 2/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 56 Female 176 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staring Life Threatening 44 Female 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 2/18/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 2/26/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 2/27/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 3/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 7/1/2008 Male 207 lb 3/9/2009 Pharmacist
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 3/10/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/9/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/11/2009
Primary
Secondary
Concomitant
Ventricular Fibrillation Required Intervention 12/25/2008 28 Female 3/11/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/20/2009 United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 4/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Pancreatitis Required Intervention 2/1/2009 57 Female 163 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 5/6/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 44 Female 6/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 4/18/2008 84 Female 7/10/2009 Physician Australia
Primary
Secondary
Concomitant
Sinus Arrhythmia Other Serious 46 Male 176 lb 7/30/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 44 Female 8/28/2009 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 10/7/2009 Physician United States
Primary
Concomitant
Cardiac Arrest Other Serious 2/20/2007 62 Female 143 lb 10/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lipase Increased Required Intervention 9/15/2009 53 Female 143 lb 10/1/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2009 86 Female 103 lb 11/18/2009 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 72 Female 12/1/2009 Physician United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 58 Female 12/4/2009 Other Health Professional France
Primary
Secondary
Skin Exfoliation Other Serious 58 Female 12/11/2009
Primary
Secondary
Weight Decreased Other Serious 66 Male 1/6/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 66 Male 1/6/2010 United States
Primary
Secondary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 58 Female 1/8/2010 Physician New Zealand
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/1/2008 78 Male 137 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Hypokalaemia Life Threatening 44 Female 2/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 58 Female 2/4/2010 Other Health Professional France
Primary
Concomitant
Renal Failure Life Threatening 12/18/2009 Male 2/8/2010 Other Health Professional France
Primary
Concomitant
Renal Failure Life Threatening 12/18/2009 Male 2/8/2010 Other Health Professional France
Primary
Concomitant
Spinal Osteoarthritis Other Serious 71 Male 3/3/2010 United Kingdom
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 71 Male 3/5/2010 United Kingdom
Primary
Secondary
Concomitant

Drug Data