Fluticasone Propionate/Salmeterol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Morbilliform Other Serious 5/26/2009 54 Male 1/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 6/1/2010 68 Male 11/12/2010 Physician Sweden
Primary
Concomitant
Overdose Hospitalization 8/19/2011 74 Male 9/7/2011 Other Health Professional
Primary
Secondary
Concomitant
Cough Hospitalization 8/19/2011 74 Male 9/9/2011 Other Health Professional
Primary
Secondary
Concomitant
Death Death 2/8/2011 78 Male 192 lb 9/22/2011 Physician Switzerland
Primary
Concomitant
Hypomagnesaemia Hospitalization 2/18/2009 80 Female 220 lb 10/13/2011 Physician Netherlands
Primary
Secondary
Concomitant
Overweight Death 12/3/2010 78 Male 192 lb 10/19/2011 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 8/19/2011 74 Male 10/20/2011 Other Health Professional
Primary
Secondary
Concomitant
Aortic Valve Incompetence Other Serious Male 10/28/2011 Lawyer United States
Primary
Concomitant
Melaena Life Threatening Male 11/3/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening Male 11/3/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening Male 11/3/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening Male 11/3/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 7/1/2011 92 Male 11/7/2011 Pharmacist New Zealand
Primary
Concomitant
Gastritis Death 7/1/2011 92 Male 11/8/2011 Pharmacist New Zealand
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/1/2011 92 Male 11/10/2011 Pharmacist New Zealand
Primary
Secondary
Concomitant
Joint Swelling Other Serious 10/27/2011 56 Female 136 lb 11/14/2011 Physician United Kingdom
Primary
Concomitant
Medication Error Life Threatening Male 11/15/2011 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 11/3/2011 79 Male 11/15/2011 Other Health Professional Netherlands
Primary
Concomitant
Supraventricular Tachycardia Other Serious Male 11/17/2011 Physician Austria
Primary
Concomitant
Diarrhoea Other Serious 11/2/2011 63 Male 207 lb 11/18/2011 Consumer United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Death 8/11/2011 93 Male 143 lb 11/28/2011 Physician Australia
Primary
Concomitant
Treatment Noncompliance Hospitalization 8/19/2011 74 Male 11/22/2011 Other Health Professional
Primary
Secondary
Concomitant
Cardiac Arrest Death 10/23/2011 84 Female 11/30/2011 Consumer Peru
Primary
Concomitant
Heart Rate Increased Death 2/25/2011 88 Female 112 lb 12/1/2011 Physician United Kingdom
Primary
Concomitant
Haematochezia Hospitalization 11/12/2010 66 Male 214 lb 12/14/2011 Physician Germany
Primary
Secondary
Concomitant
Myalgia Disability 1/1/2009 63 Male 12/21/2011 Other Health Professional Norway
Primary
Concomitant
Drug Interaction Disability 10/24/2011 83 Female 12/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pyelonephritis Life Threatening 7/2/2011 63 Female 12/22/2011 Other Health Professional France
Primary
Concomitant
Cerebrovascular Accident Life Threatening 8/22/2011 65 Male 12/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Atrophy Disability 1/1/2009 64 Male 12/19/2011 Physician Norway
Primary
Concomitant
Vulvovaginal Swelling Life Threatening 12/12/2011 69 Male 190 lb 12/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haematoma Hospitalization 9/25/2011 52 Male 163 lb 12/22/2011 Physician Germany
Primary
Concomitant
Intentional Overdose Life Threatening 2/25/2010 58 Male 146 lb 1/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Life Threatening 8/22/2011 65 Male 1/3/2012 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Hospitalization 10/25/2011 76 Female 1/6/2012 Brazil
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening Male 1/9/2012 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Cardiac Valve Disease Death 10/18/2011 34 Female 1/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 10/24/2011 83 Female 1/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
General Physical Health Deterioration Disability 1/1/2011 72 Female 141 lb 1/13/2012 Physician Germany
Primary
Concomitant
Interacting
Purpura Other Serious 9/28/2011 83 Female 143 lb 1/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Life Threatening 12/12/2011 69 Male 190 lb 1/18/2012 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/11/2011 77 Female 1/18/2012 Physician Japan
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 83 Male 265 lb 1/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Rash Pruritic Other Serious 9/28/2011 83 Female 143 lb 1/20/2012 Other Health Professional United Kingdom
Primary
Concomitant
Anxiety Other Serious 9/28/2011 83 Female 143 lb 1/17/2012 Other Health Professional
Primary
Concomitant
Rash Erythematous Other Serious 9/28/2011 83 Female 143 lb 1/24/2012 Other Health Professional United States
Primary
Concomitant
Haematochezia Hospitalization 11/12/2010 66 Male 214 lb 2/1/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Valve Disease Death 10/18/2011 89 Female 2/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Other Serious 9/28/2011 83 Female 143 lb 1/27/2012 Other Health Professional
Primary
Concomitant
Intentional Overdose Hospitalization 2/25/2010 58 Male 146 lb 2/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization Male 2/6/2012 Lawyer United States
Primary
Concomitant
Mental Disorder Hospitalization 1/1/2011 78 Male 1/31/2012 Other Health Professional Austria
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 10/25/2011 50 Female 2/9/2012 Physician United Kingdom
Primary
Concomitant
Inguinal Hernia Other Serious 1/1/2010 65 Male 187 lb 2/9/2012 Consumer Brazil
Primary
Concomitant
Pulmonary Artery Thrombosis Hospitalization 1/20/2012 62 Female 2/7/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2010 73 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 89 2/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 10/25/2011 50 Female 2/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 10/25/2011 50 Female 2/22/2012 Physician United Kingdom
Primary
Concomitant
Colitis Ischaemic Hospitalization 11/12/2010 66 Male 214 lb 2/24/2012 Physician Germany
Primary
Secondary
Concomitant
Aortic Disorder Other Serious 11/25/2009 82 Male 187 lb 2/17/2012 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/28/2012 47 Female 2/26/2012 Pharmacist United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 10/25/2011 50 Female 2/29/2012 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Death 10/17/2011 89 Female 3/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/25/2011 50 Female 3/5/2012 Physician United Kingdom
Primary
Concomitant
Gastritis Hospitalization 7/1/2011 92 Male 108 lb 3/5/2012 Pharmacist New Zealand
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/25/2011 50 Female 3/9/2012 Pharmacist United Kingdom
Primary
Concomitant
Asthenia Hospitalization 10/25/2011 76 Female 3/12/2012 Physician Brazil
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/25/2011 76 Female 3/12/2012 Consumer Brazil
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Suicidal Ideation Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Suicidal Ideation Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Akathisia Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Drug Interaction Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Akathisia Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Suicidal Ideation Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Physical Assault Other Serious 52 Female 3/16/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Interacting
Gastric Disorder Other Serious 86 Male 3/19/2012 Physician Jamaica
Primary
Concomitant
Somnolence Other Serious 10/25/2011 50 Female 3/20/2012 Pharmacist United Kingdom
Primary
Concomitant
Ischaemic Stroke Life Threatening 8/23/2011 64 Male 154 lb 3/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Violence-related Symptom Other Serious 52 Female 3/20/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 52 Female 3/23/2012 Physician Australia
Primary
Secondary
Concomitant
Drug Interaction Other Serious 3/26/2012 Australia
Primary
Secondary
Concomitant
Interacting
Ischaemic Stroke Life Threatening 8/23/2011 64 Male 154 lb 3/26/2012 Physician United Kingdom
Primary
Concomitant
Drug Hypersensitivity Other Serious 12/21/2010 76 Female 3/26/2012 Consumer Australia
Primary
Concomitant
Erysipelas Hospitalization 11/27/2008 84 Male 148 lb 3/28/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Aggression Hospitalization 11/1/2010 55 Male 3/28/2012 Physician France
Primary
Concomitant
Akathisia Hospitalization 52 Female 3/30/2012 Other Health Professional Australia
Primary
Secondary
Eosinophil Count Decreased Hospitalization 10/25/2011 50 Female 3/30/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/25/2011 50 Female 4/9/2012 Physician United Kingdom
Primary
Concomitant
Asthenia Hospitalization 62 Male 4/13/2012 Physician Israel
Primary
Secondary
Renal Failure Acute Hospitalization 76 Female 121 lb 4/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Hospitalization 76 Female 121 lb 4/19/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 76 Female 4/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 76 Female 121 lb 4/20/2012 Other Health Professional
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 76 Female 121 lb 4/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 3/1/2012 53 Male 4/25/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 76 Female 4/23/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 76 Female 121 lb 4/26/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Decreased Life Threatening 80 Female 4/27/2012 Consumer Brazil
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/23/2012 76 Female 154 lb 5/3/2012 Physician Denmark
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 4/23/2012 76 Female 154 lb 5/3/2012 Physician Denmark
Primary
Secondary
Iron Deficiency Anaemia Hospitalization 4/23/2012 76 Female 154 lb 5/4/2012 Physician Denmark
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/1/2012 89 Female 100 lb 5/4/2012 Consumer United Kingdom
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/23/2012 76 Female 154 lb 5/9/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/23/2012 76 Female 154 lb 5/11/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 4/23/2012 76 Female 154 lb 5/10/2012 Physician Denmark
Primary
Secondary
Concomitant
Ulcer Hospitalization 4/23/2012 76 Female 154 lb 5/7/2012 Physician Denmark
Primary
Secondary
Concomitant
Barrett's Oesophagus Hospitalization 9/1/2011 76 Male 5/18/2012 Physician Australia
Primary
Concomitant
Influenza Hospitalization 4/1/2012 80 Male 5/22/2012 Consumer Brazil
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/23/2012 76 Female 154 lb 5/22/2012 Physician Denmark
Primary
Concomitant
Cardiomyopathy Other Serious Female 5/25/2012 Physician United Kingdom
Primary
Concomitant
Hyperplasia Other Serious Male 5/28/2012 Consumer United States
Primary
Concomitant
Diabetes Mellitus Other Serious 6/10/2011 41 Female 6/1/2012 Physician United Kingdom
Primary
Concomitant
Mitral Valve Incompetence Hospitalization Female 170 lb 6/1/2012 Physician United Kingdom
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 4/23/2012 77 Female 154 lb 6/6/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Papilloedema Hospitalization 12/1/2011 83 Female 6/12/2012 Other Health Professional Belgium
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 6/10/2011 41 Female 6/15/2012 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Pain Upper Hospitalization 4/23/2012 77 Female 154 lb 6/15/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Fall Hospitalization 3/9/2012 78 Female 6/15/2012 Physician Italy
Primary
Secondary
Concomitant
Initial Insomnia 3/12/2012 55 Female 225 lb 7/3/2012 Consumer United States
Primary
Concomitant
Decreased Appetite Other Serious 10/1/2011 64 Male 132 lb 7/5/2012 Pharmacist Germany
Primary
Concomitant
Lacrimation Increased Other Serious 5/29/2012 71 Female 7/6/2012 Physician Italy
Primary
Concomitant
Hypotension Hospitalization 6/24/2012 90 Female 7/9/2012 Physician Denmark
Primary
Secondary
Concomitant
Dependence Other Serious 12/1/2011 73 Female 7/13/2012 Other Health Professional France
Primary
Concomitant
Atrioventricular Block Hospitalization 6/24/2012 7/17/2012 Consumer Denmark
Primary
Concomitant
Interacting
Stridor Other Serious 2/26/2009 7/18/2012 Physician United Kingdom
Primary
Concomitant
Product Quality Issue Other Serious 7/1/2012 65 Male 7/20/2012 Consumer United Kingdom
Primary
Concomitant
Ligament Sprain Other Serious 1/1/2011 83 Female 7/20/2012 Consumer Australia
Primary
Concomitant
Anal Sphincter Hypertonia Hospitalization 74 Female 7/24/2012 Consumer Lebanon
Primary
Secondary
Concomitant
Anorectal Disorder Hospitalization 7/12/2012 74 Female 7/26/2012 Consumer Lebanon
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious Male 7/27/2012 Consumer Brazil
Primary
Secondary
Concomitant
Epistaxis Hospitalization 5/3/2009 79 Male 7/30/2012 Physician Spain
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 5/18/2012 69 Male 220 lb 7/30/2012 Physician Belgium
Primary
Concomitant
Interacting
Gastric Ulcer Hospitalization 7/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 3/9/2012 78 Female 8/2/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 5/18/2012 69 Male 220 lb 8/3/2012 Physician Belgium
Primary
Concomitant
Interacting
Lower Gastrointestinal Haemorrhage Hospitalization 5/18/2012 69 Male 220 lb 8/7/2012 Physician Belgium
Primary
Concomitant
Interacting
Blood Creatine Phosphokinase Increased Hospitalization 7/1/2012 74 Female 7/25/2012 Consumer Lebanon
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization 3/23/2011 61 Female 8/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematuria Hospitalization 7/7/2012 57 Female 8/9/2012 Other Health Professional Italy
Primary
Secondary
Renal Pain Hospitalization 7/7/2012 8/8/2012 Physician Italy
Primary
Secondary
Breast Cancer Other Serious 1/1/2012 65 Female 189 lb 8/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Renal Pain Hospitalization 7/7/2012 57 Female 8/13/2012 Physician Italy
Primary
Secondary
Iron Deficiency Anaemia Hospitalization 4/23/2012 77 Female 154 lb 8/14/2012 Other Health Professional Denmark
Primary
Concomitant
Haematuria Hospitalization 7/7/2012 57 Female 8/16/2012 Physician Italy
Primary
Secondary
Renal Pain Hospitalization 7/7/2012 57 Female 8/17/2012 Consumer Italy
Primary
Secondary
Weight Decreased Other Serious 1/1/2006 55 Male 132 lb 8/20/2012 Pharmacist Germany
Primary
Concomitant
Asthma Other Serious 7/1/2012 65 Male 175 lb 8/20/2012 Consumer United Kingdom
Primary
Concomitant

Drug Data