Metoprolol Succinate combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Hospitalization 12/7/2005 74 Male 213 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 10/23/2005 74 Male 205 lb 2/7/2006 Denmark
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 10/23/2005 74 Male 205 lb 2/16/2006 Denmark
Primary
Secondary
Concomitant
Contusion Hospitalization 11/1/2004 87 Male 170 lb 12/21/2005 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/10/2005 71 Male 250 lb 12/27/2005 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/5/2006 66 Female 3/20/2006 Other Health Professional Canada
Primary
Concomitant
Visual Field Defect Other Serious 9/1/2005 75 Female 240 lb 2/9/2006 Consumer United States
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/14/2006 Norway
Primary
Concomitant
Peritonitis Bacterial Hospitalization 11/29/2005 64 Male 209 lb 4/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2/5/2006 Male 3/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/28/2006 Norway
Primary
Concomitant
Chest Pain Hospitalization 3/30/2006 5/3/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 4/24/2006 49 Male 234 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Priapism Other Serious 3/22/2006 72 Male 184 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Required Intervention 1/11/2006 76 Male 118 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Carotid Artery Occlusion Other Serious 5/14/2006 Male 156 lb 6/5/2006 Consumer United States
Primary
Concomitant
Hallucination Other Serious 74 Female 141 lb 6/1/2006 Sweden
Primary
Concomitant
Tachycardia Hospitalization 67 Female 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 5/3/2006 Physician Germany
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2006 77 Female 6/22/2006 Other Health Professional Sweden
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 86 Male 6/21/2006 Other Health Professional Canada
Primary
Concomitant
Therapy Non-responder Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 4/14/2006 76 Male 7/11/2006 Sweden
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/18/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/11/2005 46 Female 2/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/19/2006 62 Male 180 lb 6/21/2006 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/14/2006 76 Male 8/3/2006
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/27/2006 Denmark
Primary
Secondary
Concomitant
Nightmare Hospitalization 5/23/2006 76 Male 8/11/2006 Consumer Sweden
Primary
Concomitant
Pneumonia Hospitalization 2/25/2006 79 Female 8/29/2006 Denmark
Primary
Secondary
Concomitant
Nightmare Hospitalization 5/1/2006 72 Female 9/21/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Vasculitic Rash Hospitalization 5/18/2006 Male 9/21/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/10/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2006 78 Female 11/14/2006 Other Health Professional Germany
Primary
Concomitant
Wound Infection Hospitalization 5/17/2006 50 Female 176 lb 11/16/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Syncope Life Threatening 8/17/2006 60 Male 11/21/2006 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 7/29/2006 70 Male 215 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Pruritus Other Serious 8/29/2006 84 Male 197 lb 9/18/2006 Physician United States
Primary
Concomitant
Hyperkalaemia Other Serious 7/15/2006 87 Male 191 lb 8/15/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/18/2006 42 Male 126 lb 5/18/2006 United States
Primary
Concomitant
Jaundice Hospitalization 10/8/2006 66 Female 181 lb 12/1/2006 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 9/26/2006 67 Male 181 lb 11/30/2006 Physician Switzerland
Primary
Concomitant
Oedema Required Intervention 11/29/2006 61 Male 222 lb 11/29/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 11/17/2006 57 Female 211 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2006 78 Female 11/30/2006 Germany
Primary
Concomitant
Wound Infection Hospitalization 5/17/2006 50 Female 176 lb 12/4/2006 United States
Primary
Secondary
Concomitant
Expired Drug Administered 72 Male 190 lb 12/1/2006 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Disability 7/24/2006 43 Male 148 lb 12/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Cerebral Infarction Other Serious 5/28/2006 Male 154 lb 12/21/2006 Physician United States
Primary
Concomitant
Pleurisy Hospitalization 1/17/2006 68 Male 12/11/2006 Netherlands
Primary
Secondary
Somnolence Hospitalization 2/1/2005 66 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 11/29/2005 64 Male 209 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/7/2006 59 Female 198 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 1/1/2005 79 Female 12/14/2006 Physician Norway
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/15/2006 84 Male 128 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 5/17/2006 50 Female 176 lb 12/18/2006 United States
Primary
Secondary
Concomitant
Vessel Puncture Site Haematoma Hospitalization 5/8/2006 65 Female 154 lb 12/18/2006 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 12/19/2006 Male 245 lb 12/28/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2006 85 Male 141 lb 12/22/2006 United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 12/16/2006 63 Male 183 lb 12/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/7/2006 59 Female 198 lb 12/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/3/2006 74 Male 152 lb 1/5/2007 Consumer Switzerland
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 1/1/2005 72 Male 174 lb 1/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Initial Insomnia 1/1/2006 59 Female 250 lb 10/11/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/6/2006 68 Female 1/5/2007 Physician Germany
Primary
Concomitant
Dysgeusia 8/1/2006 48 Female 168 lb 10/11/2006 Consumer United States
Primary
Concomitant
Dysgeusia 7/26/2006 74 Male 208 lb 10/11/2006 Consumer United States
Primary
Concomitant
Hallucination 5/1/2006 76 Female 10/11/2006 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 59 Female 10/11/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/6/2005 67 Male 207 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 1/28/2006 83 Male 192 lb 10/6/2006 United States
Primary
Secondary
Concomitant
No Adverse Drug Effect Hospitalization 11/28/2005 54 Male 159 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/6/2005 64 Male 207 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Initial Insomnia 8/23/2006 70 Male 200 lb 10/11/2006 Consumer United States
Primary
Concomitant
Wound Necrosis Hospitalization 5/17/2006 50 Female 176 lb 1/5/2007 Poland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2006 Male 175 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 9/21/2006 Male 150 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Hospitalization 12/4/2006 72 Male 291 lb 1/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/9/2007 80 Male 234 lb 1/12/2007 Pharmacist United States
Primary
Concomitant
Tooth Loss Other Serious 1/14/2007 87 Female 138 lb 1/19/2007 United States
Primary
Concomitant
Cough Other Serious 1/5/2007 79 Male 165 lb 1/5/2007 Pharmacist United States
Primary
Concomitant
Influenza Like Illness Disability 9/1/2006 62 Male 212 lb 1/26/2007 Consumer
Primary
Concomitant
Wheezing Hospitalization 10/18/2006 66 Male 251 lb 1/30/2007 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Required Intervention 2/9/2003 83 Male 1/30/2007 United Kingdom
Primary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/1/2006 71 Male 2/8/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Drug Toxicity Hospitalization 2/3/2007 53 Male 173 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Haematochezia Hospitalization 1/10/2007 80 Male 243 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 12/21/2006 81 154 lb 2/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/30/2007 74 Male 159 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/24/2007 60 Male 172 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 2/23/2003 Male 161 lb 2/19/2007 Germany
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 11/6/2006 55 Male 164 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Polydipsia Psychogenic Hospitalization 10/12/2006 69 Male 2/13/2007 Pharmacist United States
Primary
Secondary
Concomitant
Headache Hospitalization 12/11/2006 76 Male 198 lb 2/5/2007 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 2/9/2007 61 Male 283 lb 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/7/2006 Male 181 lb 2/22/2007 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2007 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Umbilical Hernia Other Serious 11/15/2006 72 Male 2/15/2007 Physician Germany
Primary
Concomitant
Vascular Injury 11/15/2006 72 Male 2/15/2007 Physician Germany
Primary
Concomitant
Waist Circumference Increased Other Serious 47 Female 162 lb 2/22/2007 Pharmacist United States
Primary
Concomitant
Hypertension Hospitalization 1/25/2007 Male 173 lb 3/1/2007 Physician Germany
Primary
Concomitant
Vitreous Haemorrhage Other Serious 83 Male 3/5/2007 United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 75 Male 3/7/2007 Consumer United States
Primary
Concomitant
Painful Erection Other Serious 6/1/2006 43 Male 203 lb 3/8/2007 Physician Canada
Primary
Concomitant
Confusional State Hospitalization 3/1/2007 Male 214 lb 3/8/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 9/24/2006 63 Male 3/9/2007 Germany
Primary
Secondary
Concomitant
Respiratory Distress Required Intervention 12/31/2006 49 Male 229 lb 3/6/2007 Pharmacist United States
Primary
Concomitant
Skin Ulcer Hospitalization 59 Female 3/14/2007
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 46 Male 145 lb 3/22/2007 Physician United States
Primary
Concomitant
Papillary Thyroid Cancer Hospitalization 8/10/2006 Male 205 lb 3/27/2007 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2005 62 Male 3/27/2007 Physician United States
Primary
Concomitant
Implantable Defibrillator Insertion Hospitalization 1/25/2007 Male 173 lb 3/27/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2006 85 Male 141 lb 3/20/2007 United States
Primary
Secondary
Concomitant
Vomiting 9/1/2006 Female 102 lb 3/26/2007 Physician United States
Primary
Concomitant
Gingival Bleeding Hospitalization 3/15/2007 76 Male 167 lb 3/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/18/2007 82 Male 147 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 2/18/2007 82 Male 147 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Lethargy Hospitalization 1/30/2007 74 Male 227 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 3/29/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/11/2007 80 Male 219 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 2/22/2007 68 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 2/26/2007 85 Male 204 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 3/9/2007 89 Male 156 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/30/2007 Male 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Dysgeusia 11/1/2006 85 Female 140 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 10/1/2006 79 Male 187 lb 1/12/2007 Consumer United States
Primary
Concomitant
Sluggishness 9/7/2006 Male 289 lb 1/12/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 10/16/2006 Female 96 lb 3/18/2007 Pharmacist United States
Primary
Concomitant
Insomnia 9/28/2006 55 Male 245 lb 1/12/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/28/2007 77 Male 264 lb 3/30/2007 Pharmacist United States
Primary
Concomitant
Skin Necrosis Other Serious 3/29/2007 72 Male 4/10/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 8/4/2006 59 Female 4/5/2007 Consumer United States
Primary
Concomitant
Neutropenia Hospitalization 11/1/2005 75 Male 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Melaena Hospitalization 10/1/2005 55 Female 136 lb 12/13/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombosis In Device Other Serious 82 Male 12/13/2006 Physician United States
Primary
Concomitant
Depression Hospitalization 8/18/2006 38 Female 155 lb 12/13/2006 Consumer United States
Primary
Concomitant

Drug Data