Effient combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombosis In Device Hospitalization 7/30/2009 Male 8/19/2009 Physician Germany
Primary
Concomitant
Rash Other Serious 8/17/2009 45 Male 226 lb 8/20/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 9/26/2009 Female 10/2/2009 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 9/26/2009 71 Female 276 lb 10/27/2009 Physician Germany
Primary
Concomitant
Pruritus Other Serious Female 128 lb 11/6/2009 Physician Germany
Primary
Concomitant
Intracardiac Thrombus Other Serious 1/1/2009 Male 181 lb 1/18/2010 Physician United States
Primary
Concomitant
Stent Placement Other Serious 11/1/2008 Female 200 lb 2/5/2010 Consumer France
Primary
Concomitant
Sudden Cardiac Death Death 2/4/2010 Male 165 lb 3/9/2010 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 12/1/2009 67 Male 187 lb 5/6/2010 Physician Germany
Primary
Concomitant
Hypoaesthesia Hospitalization 4/1/2010 65 Male 5/11/2010 Physician Germany
Primary
Concomitant
Guillain-barre Syndrome Other Serious 4/5/2010 66 Male 198 lb 7/8/2010 Physician Germany
Primary
Concomitant
In-stent Coronary Artery Restenosis Other Serious 7/7/2010 Female 7/27/2010 Physician United States
Primary
Concomitant
Epistaxis Other Serious 7/16/2010 52 Male 7/30/2010 Consumer United States
Primary
Concomitant
Death Other Serious Male 8/3/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2009 56 Male 213 lb 8/16/2010 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection 11/1/2009 37 Male 190 lb 8/28/2010 Consumer United States
Primary
Concomitant
Rash Macular 1/1/2010 38 Male 290 lb 8/28/2010 United States
Primary
Concomitant
Myalgia 1/1/2010 53 Male 215 lb 8/28/2010 United States
Primary
Secondary
Concomitant
Muscular Weakness 4/20/2010 52 Male 177 lb 8/28/2010 United States
Primary
Concomitant
Skin Exfoliation 4/1/2010 71 Male 211 lb 8/29/2010 Consumer United States
Primary
Concomitant
Dry Skin Male 8/29/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2009 56 Male 213 lb 9/9/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 7/15/2010 59 Male 202 lb 8/30/2010 Physician United States
Primary
Concomitant
Spontaneous Haematoma Male 154 lb 11/2/2010 Physician Germany
Primary
Concomitant
Urticaria Other Serious 9/9/2010 54 Male 11/4/2010 Physician Spain
Primary
Concomitant
Pancreatitis Other Serious 71 Female 11/22/2010 Physician United States
Primary
Concomitant
Subdural Haematoma Other Serious 11/16/2010 46 Female 12/8/2010 Physician United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 9/20/2010 61 Male 194 lb 12/22/2010 Physician Germany
Primary
Concomitant
Sinus Headache 11/1/2010 68 Female 12/28/2010 Consumer
Primary
Concomitant
Headache 11/1/2010 68 Female 1/18/2011 Consumer
Primary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 11/11/2010 64 Female 143 lb 1/10/2011 Consumer United Kingdom
Primary
Concomitant
Cardiac Arrest Death Female 1/21/2011 Consumer United States
Primary
Concomitant
Haematochezia Life Threatening 1/13/2011 76 Male 162 lb 1/13/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram St Segment Elevation Other Serious 10/4/2010 47 Male 218 lb 1/31/2011 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 11/17/2010 46 Female 2/3/2011 Physician United States
Primary
Concomitant
Erythema Male 220 lb 2/16/2011 Consumer United States
Primary
Concomitant
Malaise 1/18/2011 75 Male 3/1/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious 11/22/2010 66 Female 3/4/2011 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 9/27/2010 55 Male 240 lb 3/3/2011 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/12/2011 Female 181 lb 3/16/2011 Consumer Austria
Primary
Concomitant
Erythema Hospitalization 3/1/2011 78 Male 3/14/2011 Consumer Italy
Primary
Concomitant
Malaise 1/1/2011 75 Male 3/17/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/3/2010 67 Male 176 lb 3/17/2011 Consumer Germany
Primary
Concomitant
Device Occlusion Other Serious 204 lb 3/29/2011 Physician United States
Primary
Concomitant
Lip Swelling Hospitalization 3/1/2011 78 Male 4/6/2011 Consumer Italy
Primary
Concomitant
Drug Dose Omission Other Serious 11/22/2010 66 Female 164 lb 4/11/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 4/12/2010 77 Female 161 lb 4/13/2011 Pharmacist United States
Primary
Concomitant
Pain Hospitalization 4/13/2011 71 Female 112 lb 4/14/2011 Pharmacist United States
Primary
Concomitant
Diverticulum Hospitalization 1/30/2011 62 Male 4/21/2011 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization Male 4/27/2011 Consumer Italy
Primary
Concomitant
Heart Rate Decreased Hospitalization 4/24/2009 65 Male 181 lb 4/29/2011 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 4/1/2011 60 Male 4/27/2011 Consumer United States
Primary
Concomitant
Nausea Hospitalization 3/18/2011 60 Male 164 lb 5/9/2011 Consumer United States
Primary
Concomitant
Thrombosis In Device Hospitalization 4/21/2011 60 Female 143 lb 5/13/2011 Consumer Germany
Primary
Concomitant
Thrombosis In Device Hospitalization 4/22/2011 44 Male 154 lb 5/16/2011 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/30/2011 62 Male 271 lb 5/18/2011 Physician United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 12/11/2010 74 Male 176 lb 5/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 57 Male 6/1/2011 Consumer United States
Primary
Concomitant
Headache Hospitalization 4/24/2011 68 Male 160 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Menorrhagia Other Serious 3/2/2011 44 Female 125 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious Male 147 lb 7/19/2011 Consumer United States
Primary
Concomitant
Mediastinal Operation Other Serious 6/9/2011 56 Male 227 lb 7/29/2011 Consumer United States
Primary
Concomitant
Off Label Use Hospitalization 6/1/2011 54 Male 200 lb 7/29/2011 Consumer United States
Primary
Concomitant
Heat Rash Male 250 lb 8/5/2011 Consumer United States
Primary
Concomitant
Feeling Hot Male 173 lb 8/6/2011 Consumer United States
Primary
Concomitant
Increased Tendency To Bruise Male 165 lb 8/6/2011 Consumer United States
Primary
Concomitant
Erythema Male 189 lb 8/6/2011 Consumer United States
Primary
Concomitant
Flushing 2/1/2011 72 Male 160 lb 8/6/2011 Consumer United States
Primary
Concomitant
Flushing 1/1/2009 58 Male 160 lb 8/6/2011 Consumer United States
Primary
Secondary
Concomitant
Flushing 4/1/2011 55 Male 195 lb 8/6/2011 Consumer United States
Primary
Concomitant
Asthenia 4/26/2011 Female 160 lb 8/6/2011 Consumer United States
Primary
Concomitant
Flushing 2/1/2011 Male 188 lb 8/6/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 5/3/2011 Female 177 lb 8/9/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Other Serious 11/22/2010 66 Female 164 lb 9/8/2011 Physician United States
Primary
Concomitant
Erythema Other Serious Female 9/22/2011 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 6/9/2011 56 Male 227 lb 9/28/2011 Consumer United States
Primary
Concomitant
Vascular Graft Hospitalization 64 Male 10/18/2011 Physician United States
Primary
Concomitant
Haemorrhage Life Threatening 9/24/2011 Male 10/17/2011 Physician Austria
Primary
Concomitant
Alopecia Other Serious Female 10/21/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 4/1/2011 63 Female 260 lb 10/26/2011 Physician United States
Primary
Concomitant
Thrombosis Other Serious 10/21/2011 45 Male 10/28/2011 Consumer United States
Primary
Concomitant
Swelling 4/24/2011 61 Male 180 lb 11/1/2011 Consumer United States
Primary
Concomitant
Pneumonia Legionella Hospitalization 8/5/2010 64 Female 11/4/2011 Physician Sweden
Primary
Concomitant
Depressed Mood 10/1/2011 47 Male 148 lb 11/11/2011 Consumer United States
Primary
Concomitant
Pneumonia Legionella Hospitalization 8/5/2010 64 Female 11/15/2011 Physician Sweden
Primary
Concomitant
Thrombosis In Device Other Serious 71 Male 11/15/2011 Physician United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2011 65 Female 12/2/2011 Consumer United States
Primary
Concomitant
Alopecia Female 12/7/2011 Consumer United States
Primary
Secondary
Concomitant
Hemiparesis Death 5/12/2011 Male 225 lb 12/16/2011 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 11/14/2011 40 Male 254 lb 12/21/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 12/13/2011 69 Female 12/21/2011 Consumer Brazil
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/7/2011 Female 12/22/2011 Physician Sweden
Primary
Concomitant
Depressed Mood Other Serious 10/1/2011 47 Male 148 lb 1/3/2012 Physician United States
Primary
Concomitant
Nervousness Hospitalization 2/3/2012 75 Female 2/14/2012 Consumer Brazil
Primary
Concomitant
Dyspnoea 4/25/2011 67 Female 2/17/2012 Consumer United States
Primary
Concomitant
Angina Pectoris Other Serious Female 2/23/2012 Consumer United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious Female 2/23/2012 Consumer United States
Primary
Concomitant
Muscular Weakness Female 2/29/2012 Consumer United States
Primary
Secondary
Concomitant
Beta Haemolytic Streptococcal Infection Hospitalization 11/14/2011 40 Male 254 lb 3/2/2012 Physician United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 12/24/2011 80 Male 194 lb 3/13/2012 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 12/13/2011 69 Female 3/27/2012 Consumer Brazil
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 3/8/2012 63 Male 3/29/2012 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 3/1/2012 71 Female 194 lb 4/6/2012 Consumer United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Hospitalization 4/9/2012 67 Male 4/25/2012 Consumer Italy
Primary
Concomitant
Oedema Peripheral Other Serious Female 5/2/2012 Consumer United States
Primary
Concomitant
Thrombosis In Device Other Serious 1/1/2012 55 Male 5/2/2012 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 3/1/2012 60 Male 5/2/2012 Physician United States
Primary
Concomitant
Pain 12/13/2011 69 Female 5/8/2012 Consumer Brazil
Primary
Concomitant
Beta Haemolytic Streptococcal Infection Hospitalization 11/14/2011 40 Male 254 lb 4/23/2012 Physician United States
Primary
Concomitant
Stent Placement Other Serious Male 5/22/2012 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization Male 5/25/2012 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 11/21/2011 6/1/2012 Other Health Professional Germany
Primary
Concomitant
Interacting
Hypotension Hospitalization 11/21/2011 64 Male 220 lb 6/14/2012 Other Health Professional Germany
Primary
Concomitant
Interacting
Dyspnoea 1/1/2007 58 Female 6/18/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness Disability 5/25/2012 47 Male 245 lb 6/26/2012 Physician United Kingdom
Primary
Concomitant
Chest Discomfort Other Serious 2/1/2012 57 Male 6/29/2012 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 8/8/2011 71 Female 173 lb 6/29/2012 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 3/1/2012 52 Male 208 lb 7/3/2012 Consumer United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Other Serious 1/1/2012 55 Male 7/17/2012 Consumer United States
Primary
Concomitant
Vomiting Death 4/21/2012 84 Male 220 lb 7/20/2012 Consumer United States
Primary
Concomitant
Angina Unstable Hospitalization 4/30/2012 Male 7/24/2012 Physician United States
Primary
Concomitant
Dementia Other Serious 68 Female 7/26/2012 Consumer United States
Primary
Concomitant
Stent Placement Other Serious Female 7/31/2012 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2012 57 Female 8/1/2012 Physician United States
Primary
Concomitant
Blood Glucose Increased 4/30/2011 59 Female 150 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased 7/1/2011 62 Male 210 lb 8/3/2012 Consumer United States
Primary
Concomitant
Pruritus 1/1/2011 64 Male 189 lb 8/3/2012 Physician United States
Primary
Concomitant
Insomnia 7/5/2012 51 Male 210 lb 8/3/2012 Consumer United States
Primary
Concomitant
Flushing 7/10/2012 51 Male 211 lb 8/3/2012 Consumer United States
Primary
Concomitant
Feeling Hot Male 178 lb 8/3/2012 Consumer United States
Primary
Concomitant
Feeling Hot 7/1/2011 56 Female 194 lb 8/3/2012 Consumer United States
Primary
Concomitant
Skin Burning Sensation 1/1/2011 50 Male 245 lb 8/3/2012 Consumer United States
Primary
Concomitant
Generalised Erythema Male 8/3/2012 Consumer United States
Primary
Concomitant
Flushing Female 147 lb 8/3/2012 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 64 Female 186 lb 8/13/2012 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 6/24/2012 55 Male 193 lb 8/15/2012 Physician United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2007 48 Male 145 lb 8/16/2012 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/21/2012 84 Male 220 lb 8/16/2012 Consumer United States
Primary
Concomitant
Cardiac Disorder Hospitalization 6/20/2012 79 Male 8/10/2012 Other Health Professional United States
Primary
Concomitant
Nervousness 2/3/2012 75 Female 9/4/2012 Consumer Br
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 3/2012 Male 213 lb 9/7/2012 Physician Us
Primary
Concomitant
Heart Rate Increased Hospitalization 6/20/2012 Male 9/4/2012 Physician Us
Primary
Concomitant
Pain In Jaw Other Serious 68 Male 172 lb 10/4/2012 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization 8/26/2012 57 Male 11/2/2012 Physician De
Primary
Secondary
Concomitant
Weight Increased Hospitalization Female 196 lb 9/27/2012 Consumer Us
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 8/22/2012 67 Male 10/16/2012 Consumer Us
Primary
Concomitant
Crohn's Disease Hospitalization 7/4/2012 62 Male 178 lb 10/17/2012 Physician Us
Primary
Concomitant
Nasopharyngitis 66 Male 10/25/2012 Other Health Professional Us
Primary
Concomitant
Duodenal Ulcer Haemorrhage Hospitalization 9/2012 Male 11/2/2012 Physician Us
Primary
Concomitant
Heart Valve Incompetence Hospitalization 10/23/2012 65 Male 291 lb 11/5/2012 Pharmacist Us
Primary
Concomitant

Drug Data