Phenprocoumon combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteoporosis Hospitalization 1/1/2002 64 Female 220 lb 3/29/2006 Physician Germany
Primary
Concomitant
Acute Myocardial Infarction Death 2/25/2006 62 Male 256 lb 3/30/2006 Physician Australia
Primary
Concomitant
Peritonitis Bacterial Hospitalization 11/29/2005 64 Male 209 lb 4/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Aortic Thrombosis Hospitalization 1/1/2005 65 Male 5/3/2006 Pharmacist Germany
Primary
Concomitant
Myalgia Hospitalization 3/1/2006 79 Female 5/19/2006 Physician Germany
Primary
Concomitant
Somnolence Hospitalization 2/1/2006 64 Male 214 lb 5/26/2006 Physician Germany
Primary
Concomitant
Thyrotoxic Crisis Life Threatening 5/1/2003 65 Male 12/4/2006 Germany
Primary
Concomitant
Peritonitis Hospitalization 11/29/2005 64 Male 209 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/1/2006 71 Male 2/8/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/15/2006 42 Male 207 lb 4/10/2007 Physician
Primary
Concomitant
Malaise Other Serious Male 179 lb 4/11/2008 Physician Germany
Primary
Secondary
Concomitant
Spinal Disorder Other Serious Male 179 lb 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased Other Serious 9/5/2006 Female 159 lb 9/25/2008 Germany
Primary
Concomitant
Blood Parathyroid Hormone Increased Other Serious 9/5/2006 Female 159 lb 10/1/2008 Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/15/2008 63 Male 172 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Thyroid Haemorrhage Hospitalization 9/8/2008 74 Female 3/11/2009 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 8/10/2008 75 Male 190 lb 3/19/2009 Physician Germany
Primary
Interacting
Hyperglycaemia Life Threatening 1/3/2009 67 Female 3/20/2009 Pharmacist Germany
Primary
Secondary
Interacting
Syncope Life Threatening 6/19/2008 79 Male 3/23/2009 Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 8/10/2008 75 Male 190 lb 4/3/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Pulmonary Fibrosis Hospitalization 9/20/2008 44 Male 188 lb 6/5/2009 Physician Germany
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 9/20/2008 44 Male 188 lb 6/8/2009 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 8/24/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 77 Female 8/24/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Pneumonia Hospitalization 9/20/2008 44 Male 188 lb 9/8/2009 Physician Germany
Primary
Concomitant
Urosepsis Hospitalization 2/12/2009 Male 177 lb 9/21/2009 Physician Germany
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 9/17/2009 63 Female 194 lb 10/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 1/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/1/2008 Male 218 lb 1/21/2010 Germany
Primary
Concomitant
Oesophagitis Haemorrhagic Hospitalization 12/2/2008 75 Male 192 lb 2/1/2010 Physician Germany
Primary
Secondary
Interacting
Haematuria Hospitalization 9/2/2008 68 Male 174 lb 2/8/2010 Physician Germany
Primary
Interacting
Myalgia Hospitalization 1/1/2009 81 Female 2/9/2010 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 9/1/2009 81 Female 2/23/2010 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/1/2009 Female 99 lb 3/15/2010 Physician Germany
Primary
Secondary
Concomitant
Protein Total Decreased Life Threatening 1/26/2010 65 Female 99 lb 3/16/2010 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 4/14/2010 Other Health Professional Netherlands
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 77 Female 4/14/2010 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Rheumatoid Arthritis Other Serious 9/1/2009 81 Female 4/14/2010 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Factor Positive Other Serious 9/1/2009 81 Female 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/8/2010 60 Male 152 lb 4/21/2010 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 8/10/2008 75 Male 190 lb 4/27/2010 Other Health Professional Germany
Primary
Secondary
Interacting
Torsade De Pointes Other Serious 2/24/2010 76 Male 194 lb 5/11/2010 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 3/8/2010 60 Male 150 lb 6/1/2010 Physician Germany
Primary
Concomitant
Hyperkalaemia Life Threatening 12/1/2008 79 Female 152 lb 6/15/2010 Physician Germany
Primary
Interacting
Hypersensitivity Hospitalization 5/31/2007 71 Female 181 lb 7/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 7/7/2010 79 Male 198 lb 7/23/2010 Physician Germany
Primary
Concomitant
Long Qt Syndrome Hospitalization 7/19/2010 64 Female 159 lb 8/3/2010 Physician Germany
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/25/2010 54 Male 269 lb 9/9/2010 Physician Denmark
Primary
Concomitant
Renal Failure Acute Life Threatening 2/1/2010 79 Female 176 lb 10/18/2010 Physician Germany
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/9/2008 65 Female 11/24/2010 Consumer Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/12/2009 59 Male 177 lb 11/29/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/8/2010 60 Male 152 lb 12/14/2010 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 3/8/2010 60 Male 150 lb 12/14/2010 Physician Germany
Primary
Concomitant
Hyperglycaemia Life Threatening 1/3/2009 67 Female 256 lb 12/28/2010 Pharmacist Germany
Primary
Secondary
Interacting
Drug Interaction Other Serious 77 Female 12/29/2010 Physician Netherlands
Primary
Concomitant
Interacting
Pneumonitis Other Serious 11/1/2009 65 Female 99 lb 1/5/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Abscess Hospitalization 11/1/2009 65 Female 99 lb 1/5/2011 Physician Germany
Primary
Secondary
Concomitant
Coagulation Test Abnormal Other Serious 77 Female 1/6/2011 Physician Netherlands
Primary
Concomitant
Interacting
Mitral Valve Incompetence Other Serious 11/1/2009 65 Female 99 lb 1/21/2011 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/22/2010 85 Female 183 lb 2/18/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2010 68 Male 3/4/2011 Physician Germany
Primary
Concomitant
Hepatitis B Dna Increased Other Serious 56 Male 3/8/2011 Consumer Germany
Primary
Concomitant
Cardioactive Drug Level Increased Other Serious 1/1/2009 71 Female 207 lb 3/21/2011 Consumer Germany
Primary
Secondary
Concomitant
Hepatitis B Dna Increased Other Serious 56 Male 4/6/2011 Consumer Germany
Primary
Concomitant
Pancytopenia Death 1/30/2011 77 Male 207 lb 4/20/2011 Physician Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 4/15/2011 47 Male 4/20/2011 Pharmacist Germany
Primary
Concomitant
Sepsis Hospitalization 1/30/2011 77 Male 207 lb 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatitis B Dna Increased Other Serious 56 Male 4/26/2011 Physician Germany
Primary
Concomitant
Agitation Hospitalization 5/1/2011 74 Male 5/12/2011 Pharmacist Germany
Primary
Concomitant
Hallucination Hospitalization 5/1/2011 74 Male 5/27/2011 Pharmacist Germany
Primary
Concomitant
Tremor Hospitalization 4/15/2011 47 Male 6/20/2011 Pharmacist Germany
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vaginal Abscess Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Refractory Anaemia Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anti-erythropoietin Antibody Positive Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anti-erythropoietin Antibody Positive Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Colonic Polyp Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anti-erythropoietin Antibody Positive Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypopnoea Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data