Simvastatin combined with Zyrtec

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toxic Epidermal Necrolysis Life Threatening 1/14/2006 69 Male 2/21/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Skin Hyperpigmentation 1/1/2006 57 Female 5/23/2006 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/28/2006 83 Male 153 lb 9/18/2006 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis 3/2/2006 Female 12/14/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/21/2007 Male 230 lb 2/9/2007 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 9/1/2003 63 Female 2/23/2007 Norway
Primary
Secondary
Concomitant
Throat Tightness Other Serious 3/1/2007 Female 145 lb 4/24/2007 Consumer United States
Primary
Concomitant
Cardiac Disorder Hospitalization 57 Female 6/28/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 28 Female 240 lb 6/19/2007 Consumer United States
Primary
Concomitant
Impaired Driving Ability Other Serious 4/29/2007 Female 130 lb 8/10/2007 Consumer United States
Primary
Concomitant
Nipple Exudate Bloody Other Serious 1/1/2004 Female 180 lb 9/17/2007 Consumer United States
Primary
Secondary
Concomitant
Impaired Driving Ability Other Serious 4/29/2007 Female 130 lb 10/10/2007 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/14/2007 85 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Oral Candidiasis 1/1/2004 76 Female 12/28/2007 Consumer United States
Primary
Concomitant
Death Death 8/27/2007 48 Male 217 lb 1/16/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 148 lb 1/28/2008 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 10/1/2007 Male 244 lb 2/22/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection 10/28/2007 79 Female 2/28/2008 Physician Netherlands
Primary
Concomitant
Oedema Peripheral 1/17/2007 28 Female 240 lb 2/28/2007 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Increased Hospitalization 3/1/2007 50 Female 150 lb 3/7/2008 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 28 Female 240 lb 9/4/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2008 80 Male 218 lb 4/30/2008 United States
Primary
Concomitant
Musculoskeletal Discomfort 5/8/2008 72 Male 210 lb 5/30/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 11/1/2006 Female 245 lb 6/1/2008 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 10/28/2007 79 Female 6/12/2008 Physician Netherlands
Primary
Concomitant
Stomatitis 2/28/2008 63 Female 180 lb 6/18/2008 United States
Primary
Concomitant
Pituitary-dependent Cushing's Syndrome Other Serious 55 Female 170 lb 6/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 6/26/2008 64 Female 119 lb 7/8/2008 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/1/2008 Male 350 lb 7/9/2008 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 9/12/2007 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/1/2006 Female 245 lb 7/29/2008 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 6/1/2008 Male 350 lb 7/31/2008 Physician United States
Primary
Concomitant
Vision Blurred 2/1/2008 81 Male 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral 4/1/2008 69 Female 148 lb 7/30/2008 Physician United States
Primary
Concomitant
Dyspnoea 5/8/2008 72 Male 210 lb 8/22/2008 United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 4/1/2008 Female 190 lb 9/2/2008 Consumer United States
Primary
Secondary
Concomitant
Back Pain 67 Male 216 lb 9/4/2008 Consumer United States
Primary
Concomitant
Occult Blood Positive Other Serious 6/26/2008 64 Female 119 lb 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2006 Male 245 lb 10/24/2008 Physician United States
Primary
Concomitant
Pallor Other Serious 1/1/2008 Male 169 lb 10/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue 6/4/2008 53 Female 11/13/2008 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 4/1/2008 Female 190 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2006 55 Male 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 11/24/2008 56 Male 11/25/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/22/2008 Female 210 lb 12/12/2008 United States
Primary
Concomitant
Tinnitus 1/1/2008 54 Female 220 lb 12/15/2008 United States
Primary
Concomitant
Urosepsis Hospitalization 10/14/2008 75 Female 135 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 12/1/2008 Female 216 lb 2/27/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/18/2008 Male 2/27/2009 Physician United States
Primary
Concomitant
Hallucination, Visual Other Serious 2/1/2009 3/2/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 1/21/2009 73 Male 232 lb 3/4/2009 Physician United States
Primary
Concomitant
Muscle Spasms 3/5/2009 Female 190 lb 3/5/2009 Physician United States
Primary
Concomitant
Ear Infection 1/8/2009 Female 178 lb 3/14/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2009 53 Female 194 lb 3/16/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/18/2008 Male 3/24/2009 Physician United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/18/2008 Male 3/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/19/1999 57 Female 118 lb 4/17/2009 United States
Primary
Concomitant
Tooth Erosion Hospitalization 71 Male 4/17/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Death 3/23/2009 Male 140 lb 4/24/2009 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 3/24/2009 77 Female 4/22/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/18/2008 Male 5/6/2009 Physician United States
Primary
Concomitant
Impaired Driving Ability 5/4/2009 Female 167 lb 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting 7/28/2008 Female 140 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 5/9/2009 Female 162 lb 5/28/2009 United States
Primary
Concomitant
Pain Hospitalization 5/5/2009 28 Male 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 5/5/2009 28 Male 6/9/2009 Physician United States
Primary
Secondary
Concomitant
Renal Injury Other Serious 3/21/2009 Female 168 lb 6/18/2009 United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 5/9/2009 Female 162 lb 6/19/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 71 Female 6/14/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/21/2009 Female 168 lb 6/29/2009 United States
Primary
Concomitant
Vomiting Other Serious 62 Female 6/30/2009 Lawyer United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 7/16/2009 Other Health Professional United States
Primary
Concomitant
Anaemia Hospitalization 3/1/2009 50 Female 7/23/2009 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 9/12/2007 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Tremor Required Intervention Female 240 lb 7/26/2009 Consumer United States
Primary
Concomitant
Wheezing Other Serious 11/21/2007 80 Female 99 lb 8/4/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 71 Female 7/22/2009 United States
Primary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 8/7/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2007 Male 8/10/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 71 Female 8/5/2009 United States
Primary
Concomitant
Vomiting Other Serious 57 Female 8/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 8/11/2009 United States
Primary
Concomitant
Chest Pain Hospitalization 8/23/2009 50 Female 211 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2007 Male 8/26/2009 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious 1/1/2008 72 Female 159 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 5/9/2009 Female 162 lb 9/10/2009 United States
Primary
Concomitant
Vomiting Other Serious 57 Female 9/4/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 9/8/2009 United States
Primary
Concomitant
Respiratory Distress Hospitalization 71 Male 9/8/2009 United States
Primary
Concomitant
Rash Generalised Other Serious 9/1/2009 41 Female 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rash Erythematous Other Serious 9/1/2009 41 Female 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 Female 156 lb 9/19/2009 United States
Primary
Concomitant
Weight Increased 12/1/2000 50 Male 275 lb 9/23/2009 United States
Primary
Concomitant
Medication Residue 7/23/2009 Male 9/24/2009 Other Health Professional
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 5/12/2008 66 Male 208 lb 7/30/2009 United States
Primary
Concomitant
Vomiting Other Serious 56 Female 9/4/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2008 Female 260 lb 10/15/2009 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 71 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 59 Female 10/26/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Female 11/2/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 71 Male 11/4/2009 United States
Primary
Concomitant
Tooth Impacted Other Serious 4/9/2005 Female 100 lb 11/17/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 1/1/2008 71 Female 159 lb 11/18/2009 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 1/1/2006 55 Male 11/11/2009 Consumer United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/13/2008 Female 11/19/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/9/2004 52 Male 190 lb 11/26/2009 Consumer United States
Primary
Concomitant
Wound Hospitalization 71 Male 11/19/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 70 Female 11/18/2009 United States
Primary
Concomitant
Myocardial Infarction Death 7/12/2009 Female 12/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/9/2004 52 Male 190 lb 12/2/2009 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/3/2009 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/18/2008 Male 12/1/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 7/27/2006 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 12/17/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 1/19/2010 Other Health Professional United States
Primary
Concomitant
Death Death Male 171 lb 1/19/2010 Consumer United States
Primary
Concomitant
Wound Hospitalization 71 Male 1/11/2010 United States
Primary
Concomitant
Injection Site Urticaria 9/7/2009 Male 138 lb 1/29/2010 United States
Primary
Concomitant
Tinnitus 11/3/2009 Female 2/2/2010 Physician
Primary
Concomitant
Wound Hospitalization 71 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Viral Infection Other Serious 4/9/2005 Female 100 lb 2/11/2010 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 4/9/2005 Female 100 lb 2/23/2010 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 73 Female 2/5/2010 United States
Primary
Concomitant
Rash Macular 62 Male 2/26/2010 Consumer United States
Primary
Concomitant
Somnolence 4/1/2009 73 Male 2/26/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 4/9/2005 Female 100 lb 3/17/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 Female 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 12/21/2008 49 Male 385 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/6/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 64 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Attack Other Serious 12/1/2009 55 Female 240 lb 4/7/2010 Consumer
Primary
Secondary
Memory Impairment Other Serious 12/1/2009 55 Female 240 lb 4/7/2010 Consumer United States
Primary
Secondary
Memory Impairment Other Serious 12/1/2009 55 Female 4/8/2010 Consumer United States
Primary
Secondary
Memory Impairment Other Serious Female 4/8/2010 Consumer United States
Primary
Secondary
Memory Impairment Other Serious 12/1/2009 56 Female 240 lb 4/14/2010 Consumer United States
Primary
Secondary
Vitreous Haemorrhage Other Serious 1/1/2005 74 Female 100 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Vascular Anomaly Other Serious 1/1/2003 4/15/2010 Physician United States
Primary
Concomitant
Memory Impairment Other Serious 12/1/2009 55 Female 240 lb 4/15/2010 Consumer United States
Primary
Secondary

Drug Data