Actos combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Protein Urine Other Serious 8/1/2005 54 Male 190 lb 12/30/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Required Intervention 12/9/2005 82 Male 272 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 1/10/2006 63 Female 1/24/2006 Physician Japan
Primary
Secondary
Concomitant
Fat Tissue Increased Hospitalization 12/15/2003 53 Female 1/25/2006 Netherlands
Primary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 1/10/2006 63 Female 2/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 1/10/2006 63 Female 3/29/2006 Japan
Primary
Secondary
Concomitant
Intentional Drug Misuse Other Serious 71 Male 238 lb 4/20/2006 United States
Primary
Concomitant
Cardiac Failure Death 3/9/2006 Male 6/20/2006 Physician Netherlands
Primary
Concomitant
Vision Blurred Other Serious 8/1/2005 73 Male 7/25/2006 Canada
Primary
Concomitant
Self-medication 7/1/2006 66 Male 165 lb 8/14/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/22/2006 68 Male 9/11/2006 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/22/2006 68 Male 9/21/2006 Germany
Primary
Concomitant
Respiratory Tract Infection Other Serious 5/30/2006 74 Female 10/3/2006 Other Health Professional Sweden
Primary
Concomitant
Sinus Tachycardia Hospitalization 6/1/2006 73 Female 10/23/2006 Australia
Primary
Concomitant
Ventricular Dysfunction Other Serious 58 Male 10/27/2006 United Kingdom
Primary
Concomitant
Pulmonary Hypertension Other Serious 5/30/2006 74 Female 11/8/2006 Other Health Professional Sweden
Primary
Concomitant
Expired Drug Administered 72 Male 190 lb 12/1/2006 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 53 Male 12/19/2006 United Kingdom
Primary
Concomitant
Platelet Count Decreased Required Intervention 11/15/2006 74 Male 12/27/2006 United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 10/27/2006 85 Male 183 lb 12/28/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 1/3/2007 54 Female 229 lb 1/19/2007 Physician Netherlands
Primary
Concomitant
Nightmare Other Serious 12/1/2006 Male 180 lb 1/26/2007 Consumer United States
Primary
Concomitant
Weight Increased Death 5/1/2006 65 Male 1/25/2007 Germany
Primary
Concomitant
Gynaecomastia Other Serious 12/1/2006 Male 1/25/2007 United Kingdom
Primary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 1/31/2007 Physician Australia
Primary
Concomitant
Weight Decreased Hospitalization 1/3/2007 54 Female 229 lb 1/30/2007 Physician Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 1/3/2007 54 Female 229 lb 2/8/2007 Physician Netherlands
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 11/30/2006 58 Female 2/15/2007 Spain
Primary
Concomitant
Weight Decreased Hospitalization 1/3/2007 54 Female 229 lb 2/22/2007 Physician Netherlands
Primary
Secondary
Concomitant
Pyelonephritis Other Serious 1/10/2006 63 Female 3/13/2007 Japan
Primary
Secondary
Concomitant
Drug Ineffective 1/29/2007 74 Male 230 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Joint Swelling Required Intervention 11/1/2006 61 Female 3/26/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Required Intervention 7/1/2006 70 Female 3/26/2007 France
Primary
Concomitant
Skin Discolouration Death 2/20/2007 60 Female 4/4/2007 Physician Greece
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 10/27/2006 85 Male 183 lb 3/29/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 1/1/2004 Female 240 lb 4/11/2007 Consumer United States
Primary
Concomitant
Skin Discolouration Death 2/20/2007 60 Female 4/19/2007 Physician Greece
Primary
Concomitant
Stomach Discomfort 12/14/2006 63 Male 2/16/2007 Consumer United States
Primary
Concomitant
Gynaecomastia Required Intervention 12/1/2006 49 Male 5/8/2007 United Kingdom
Primary
Concomitant
Humerus Fracture Hospitalization 4/15/2007 70 Female 5/8/2007 United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2007 79 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Oedema Peripheral Disability 10/1/2006 52 Male 209 lb 5/31/2007 Physician Germany
Primary
Concomitant
Chest Pain Hospitalization 6/1/2006 51 Female 180 lb 6/6/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/2/2007 69 Female 120 lb 6/10/2007 Other Health Professional United States
Primary
Concomitant
Vomiting 1/5/2007 44 Female 138 lb 4/10/2007 Consumer United States
Primary
Concomitant
Epilepsy Other Serious 6/6/2007 56 Female 190 lb 6/27/2007 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 5/31/2007 59 Female 227 lb 6/22/2007 Physician United States
Primary
Concomitant
Humerus Fracture Other Serious 4/15/2007 70 Female 7/3/2007 United Kingdom
Primary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/22/2007 Female 243 lb 7/23/2007 Physician United States
Primary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 11/1/2005 61 Female 7/19/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/2/2007 61 Male 198 lb 7/30/2007 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 6/6/2007 56 Female 190 lb 7/31/2007 Physician United Kingdom
Primary
Concomitant
Tooth Infection Other Serious 1/1/2007 Male 7/31/2007 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 5/10/2007 55 Male 7/25/2007 United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 10/27/2006 85 Male 183 lb 7/30/2007 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 10/27/2005 62 Female 7/31/2007 Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 7/1/2007 71 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 66 Male 230 lb 8/15/2007 Consumer United States
Primary
Concomitant
Cardiac Murmur Hospitalization 7/1/2007 74 Female 176 lb 8/21/2007 United States
Primary
Concomitant
Hunger 3/1/2007 37 Female 7/11/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 6/1/2007 74 Male 7/11/2007 Consumer United States
Primary
Concomitant
Vision Blurred Required Intervention 8/15/2007 68 Male 9/7/2007 United Kingdom
Primary
Concomitant
Syncope Hospitalization 8/13/2007 69 Male 303 lb 9/5/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2005 Female 9/13/2007 Physician United States
Primary
Concomitant
Stress Other Serious 10/1/2006 Female 170 lb 9/13/2007 Consumer United States
Primary
Concomitant
Nipple Exudate Bloody Other Serious 1/1/2004 Female 180 lb 9/17/2007 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion 8/6/2007 53 Male 9/12/2007 Germany
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2006 33 Female 230 lb 9/18/2007 Physician United States
Primary
Concomitant
Headache Other Serious 8/14/2007 56 Female 9/17/2007 United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 7/23/2007 81 Male 8/9/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 Female 187 lb 9/25/2007 Physician United States
Primary
Concomitant
Blood Triglycerides Increased Other Serious 8/31/2007 54 Male 9/21/2007 Other Health Professional Spain
Primary
Concomitant
Stress Other Serious 10/1/2006 Female 170 lb 9/26/2007 Consumer United States
Primary
Concomitant
Leg Amputation Hospitalization 65 Female 9/25/2007 Germany
Primary
Concomitant
Syncope Vasovagal Hospitalization 8/13/2007 Male 303 lb 10/9/2007 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 75 Female 10/6/2007 United Kingdom
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Gynaecomastia Other Serious 2/10/2006 72 Male 10/29/2007 United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 11/1/2006 43 Male 160 lb 10/22/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2007 Female 240 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 10/29/2007 80 Male 11/26/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 11/28/2007 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/3/2007 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/5/2007 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/20/2007 69 Male 193 lb 11/16/2007 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/7/2007 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Life Threatening 11/18/2007 62 Male 12/11/2007 Physician United States
Primary
Concomitant
Retching 3/1/2007 37 Female 10/9/2007 Consumer United States
Primary
Concomitant
Weight Increased 7/1/2007 Female 170 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia Related To Another Mental Condition Hospitalization 5/31/2007 Female 227 lb 12/19/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 187 lb 12/28/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/4/2007 79 Male 1/25/2008 United States
Primary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Hospitalization 7/2/2007 61 Male 198 lb 2/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/21/2007 72 Male 2/8/2008 Physician United States
Primary
Concomitant
Restlessness Other Serious 12/10/2007 Female 2/11/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/10/2007 Female 2/19/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2007 Female 162 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/4/2008 62 Female 176 lb 3/1/2008 Consumer Brazil
Primary
Concomitant
Angina Pectoris Other Serious 2/4/2008 72 Male 2/28/2008 Other Health Professional Germany
Primary
Concomitant
Retching 3/1/2007 37 Female 1/10/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2007 Male 3/5/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/10/2007 66 Male 3/7/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 12/10/2007 Female 3/4/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 11/1/2007 63 Female 3/10/2008 Other Health Professional United States
Primary
Concomitant
Joint Swelling Other Serious 3/1/2007 65 Male 3/3/2008 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/21/2008 63 Male 3/14/2008 Consumer Finland
Primary
Secondary
Concomitant
Oedema Peripheral 10/1/2007 3/13/2008 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 3/3/2008 77 Male 223 lb 4/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 3/15/2008 87 Female 99 lb 4/7/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 4/10/2008 Physician United States
Primary
Concomitant
Skin Irritation Other Serious 9/29/2007 34 Female 4/15/2008 United Kingdom
Primary
Concomitant
Weight Increased Disability 12/1/2007 41 Male 4/15/2008 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 Male 282 lb 4/16/2008 Consumer United States
Primary
Concomitant
Nasal Congestion Male 8/16/2007 Other Health Professional United States
Primary
Concomitant
Thrombosis Hospitalization 3/15/2008 87 Female 99 lb 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/2/2008 69 Male 4/29/2008 Japan
Primary
Concomitant
Visual Disturbance 4/1/2008 Male 5/7/2008 Physician Canada
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 Female 159 lb 5/16/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/10/2007 Female 5/23/2008 Physician United States
Primary
Concomitant
Lacrimation Increased 4/16/2008 79 Male 201 lb 5/29/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Life Threatening 3/1/2008 67 Male 5/22/2008 France
Primary
Secondary
Vitamin B12 Deficiency Death 8/1/2007 Female 6/6/2008 Lawyer United States
Primary
Concomitant
Lacrimation Increased 5/7/2008 Female 6/6/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/2/2008 69 Male 6/2/2008 Japan
Primary
Concomitant
Weight Increased 7/1/2007 Female 170 lb 6/12/2008 Consumer Japan
Primary
Secondary
Concomitant
Weight Decreased 6/1/2007 61 Male 4/10/2008 Consumer United States
Primary
Concomitant
Renal Pain 7/1/2007 34 Female 183 lb 4/10/2008 Consumer United States
Primary
Concomitant
Vomiting 10/1/2007 63 Male 4/10/2008 Consumer United States
Primary
Concomitant
Depressed Mood Other Serious 4/18/2008 60 Male 6/18/2008 United Kingdom
Primary
Concomitant
Hallucination, Visual Hospitalization 5/11/2008 Male 152 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 5/1/2008 Male 7/10/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/2/2007 53 Female 210 lb 7/10/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 7/21/2008 Physician United States
Primary
Concomitant
Somnambulism Hospitalization 6/28/2008 Female 7/27/2008 Consumer United States
Primary
Concomitant
Lacrimation Increased 5/7/2008 Female 8/1/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/30/2008 66 Female 190 lb 8/5/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2008 52 Female 218 lb 8/21/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/2/2007 53 Female 210 lb 8/20/2008 Consumer United States
Primary
Concomitant
Hallucination, Visual Hospitalization 5/11/2008 Male 146 lb 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Male 8/15/2008 Physician United States
Primary
Concomitant
Flank Pain 5/1/2008 68 Male 8/15/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 8/12/2008 Male 154 lb 9/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/2/2007 61 Male 198 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant

Drug Data