Levetiracetam combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 1/1/2004 64 Male 203 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/25/2006 59 Male 288 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sedation Other Serious 9/1/2006 46 Male 225 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious 9/1/2006 Male 211 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 11/4/2006 58 Male 259 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/23/2007 64 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 5/30/2008 Other Health Professional United States
Primary
Secondary
Oral Intake Reduced Hospitalization 86 Male 6/2/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/12/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/11/2008 Other Health Professional United States
Primary
Secondary
Oral Intake Reduced Hospitalization 86 Male 6/12/2008 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 86 Male 6/24/2008 United States
Primary
Secondary
Nausea Hospitalization 86 Male 6/22/2008 United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 2/1/2008 52 Male 170 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 7/21/2008 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 7/23/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 1/1/2008 86 Male 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/25/2008 76 Female 118 lb 9/4/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/24/2008 76 Female 118 lb 9/10/2008 Physician United States
Primary
Concomitant
Splenic Infarction Hospitalization 52 Male 9/17/2008 United States
Primary
Secondary
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 10/9/2008 72 Female 10/20/2008 Pharmacist United States
Primary
Concomitant
Renal Impairment Life Threatening 86 Male 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/2/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 1/26/2009 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 157 lb 1/30/2009 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/1/2008 57 Male 154 lb 2/10/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/1/2008 57 Male 154 lb 2/17/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/1/2008 57 Male 154 lb 3/2/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 3/18/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 3/26/2009 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 12/3/2008 61 Male 12/5/2008 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 2/2/2006 Male 5/1/2009 France
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 5/4/2009 Physician Germany
Primary
Concomitant
Cerebral Infarction Required Intervention 2/3/2009 47 Female 140 lb 2/16/2009 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 84 Female 157 lb 4/29/2009 United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 5/12/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 5/22/2009 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Male 215 lb 6/1/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/2/2006 Male 6/5/2009 France
Primary
Concomitant
Normal Pressure Hydrocephalus Required Intervention 4/7/2009 89 Male 4/8/2009 Pharmacist United States
Primary
Concomitant
Product Substitution Issue Life Threatening 5/20/2009 45 Female 5/28/2009 Pharmacist United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 7/3/2009 Physician Germany
Primary
Concomitant
Epilepsy 6/19/2009 55 Male 183 lb 7/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 9/1/2009 Consumer Denmark
Primary
Concomitant
Nocardiosis Hospitalization Female 9/10/2009 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 60 Male 215 lb 9/16/2009 United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 9/28/2009 United States
Primary
Concomitant
Rash Pruritic Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Drug Hypersensitivity Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Rash Pruritic Hospitalization 52 Male 9/18/2009 United States
Primary
Secondary
Nausea Other Serious 86 Male 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/25/2008 Male 154 lb 10/20/2009 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/17/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/25/2008 Male 154 lb 10/27/2009 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 10/17/2009 Other Health Professional United States
Primary
Secondary
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/12/2008 84 Female 157 lb 11/10/2009 Physician Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/4/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 11/12/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Neutrophil Count Decreased Required Intervention 9/23/2009 60 Male 136 lb 10/5/2009 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 9/1/2009 62 Female 265 lb 11/13/2009 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 11/24/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Syncope Life Threatening 6/12/2008 84 Female 157 lb 12/5/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/25/2008 57 Male 154 lb 1/18/2010 Physician Germany
Primary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 185 lb 1/22/2010 United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 56 Male 180 lb 2/4/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious 56 Male 180 lb 2/10/2010 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 185 lb 2/15/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/25/2008 57 Male 132 lb 2/23/2010 Physician Germany
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 9/7/2009 63 Male 173 lb 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Depression Other Serious 73 Male 205 lb 3/4/2010
Primary
Secondary
Hepatic Function Abnormal Other Serious 9/7/2009 63 Male 173 lb 3/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 78 Male 142 lb 4/7/2010 Physician United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 4/15/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 70 Male 5/12/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 6/14/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 2/19/2010 27 Female 112 lb 7/1/2010 Consumer United States
Primary
Secondary
Concomitant
Tablet Issue Other Serious 5/1/2010 64 Male 223 lb 7/16/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 70 Male 7/29/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Vascular Anomaly Other Serious 56 Male 180 lb 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/10/2010 71 Female 179 lb 8/7/2010 Pharmacist United States
Primary
Concomitant
Speech Disorder Other Serious 5/1/2010 64 Male 223 lb 7/30/2010 United States
Primary
Concomitant
Off Label Use Other Serious Male 211 lb 9/2/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/25/2008 57 Male 132 lb 9/15/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 9/14/2010 Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 2/19/2010 57 Male 172 lb 9/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 60 Male 9/30/2010 Other Health Professional Germany
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 10/12/2010 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious 5/1/2010 70 Female 130 lb 10/21/2010 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Blistering 69 Female 10/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Drug Ineffective Other Serious 5/1/2010 69 Female 130 lb 10/28/2010 United States
Primary
Secondary
Concomitant
Dysstasia Other Serious 10/1/2010 77 Male 151 lb 10/29/2010 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2007 Female 11/23/2010 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 8/29/2010 64 Female 175 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 11/23/2010 Other Health Professional Germany
Primary
Concomitant
Tachycardia Hospitalization Male 141 lb 1/11/2011 Physician United States
Primary
Concomitant
Tremor Disability 12/25/2010 84 Male 198 lb 1/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Other Serious 1/1/2010 83 Male 2/7/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 5/1/2010 70 Female 130 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Inadequately Controlled Other Serious 5/1/2010 70 Female 130 lb 2/28/2011 United States
Primary
Secondary
Concomitant
Hypophagia Hospitalization 12/2/2010 65 Male 145 lb 3/9/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 82 Male 2/25/2011 United Kingdom
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 12/18/2010 3/12/2011 Other Health Professional United States
Primary
Concomitant
Aplastic Anaemia Hospitalization 78 Female 3/3/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 82 Male 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 82 Male 3/30/2011 Other Health Professional
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased 4/30/2010 70 Male 7/8/2010 Physician United States
Primary
Secondary
Drug Tolerance Other Serious 6/1/2010 52 Female 251 lb 4/18/2011 Consumer United States
Primary
Concomitant
Headache Male 4/21/2011 United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/18/2010 4/29/2011 Other Health Professional United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 11/25/2008 57 Male 132 lb 5/3/2011 Other Health Professional United States
Primary
Concomitant
Oesophageal Carcinoma Other Serious Female 5/4/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 4/11/2011 67 Male 220 lb 5/6/2011 Consumer United States
Primary
Concomitant
Back Pain Hospitalization 3/1/2000 39 Male 5/9/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 78 Female 5/4/2011 Physician United Kingdom
Primary
Concomitant
Pain Other Serious Female 5/10/2011 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 6/6/2011 68 Female 140 lb 6/20/2011 Physician United States
Primary
Secondary
Concomitant
Pulseless Electrical Activity Death 1/25/2011 66 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Renal Haemorrhage Other Serious 3/1/2011 57 Female 7/15/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 8/31/2011 75 Male 9/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cystitis Hospitalization 9/1/2008 54 Male 9/8/2011 Consumer United States
Primary
Concomitant
Vomiting Death 3/9/2011 82 Male 10/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 3/9/2011 82 Male 10/10/2011 Consumer Germany
Primary
Concomitant
Frustration Other Serious 10/1/2010 61 Male 287 lb 10/12/2011 Consumer United States
Primary
Secondary
Concomitant
Dehydration Other Serious 3/9/2011 82 Male 10/5/2011 Other Health Professional
Primary
Concomitant
Cardiac Arrest Death 3/9/2011 82 Male 10/7/2011 Other Health Professional Denmark
Primary
Concomitant
Lymphocyte Count Increased Disability 5/12/2011 45 Male 10/17/2011 Physician United Kingdom
Primary
Concomitant
Accident Hospitalization 10/13/2011 81 Female 10/20/2011 Physician Germany
Primary
Concomitant
Diarrhoea Male 185 lb 10/26/2011 Other Health Professional United States
Primary
Concomitant
Drug Hypersensitivity Male 185 lb 10/28/2011 Physician United States
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 10/3/2011 Male 203 lb 10/31/2011 Other Health Professional
Primary
Concomitant
Dermatitis Exfoliative Hospitalization 10/3/2011 Male 203 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data