Esomeprazole combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 3/1/2005 70 Male 1/12/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Therapy Non-responder Death 46 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Gastrointestinal Haemorrhage Life Threatening 7/18/2005 56 Female 2/22/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 2/4/2006 89 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 8/1/2005 Male 12/27/2005 Consumer United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 12/5/2005 61 Female 4/3/2006 Physician Netherlands
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/14/2006 Norway
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 4/28/2006 Norway
Primary
Concomitant
Rhabdomyolysis Other Serious 65 Female 5/10/2006
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/19/2005 65 Female 176 lb 5/11/2006
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Haemoptysis Hospitalization 3/27/2006 Male 148 lb 7/7/2006 Norway
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Visual Disturbance 66 Female 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 10/10/2007 Other Health Professional Australia
Primary
Concomitant
Interstitial Lung Disease Other Serious 68 Male 10/15/2007 Other Health Professional Australia
Primary
Secondary
Interstitial Lung Disease Hospitalization 7/4/2007 Male 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/5/2007 Physician United Kingdom
Primary
Concomitant
Tetany Disability 8/1/2007 60 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Other Serious 10/5/2007 56 Female 227 lb 11/15/2007
Primary
Concomitant
Angioedema Life Threatening 8/3/2007 60 Female 11/26/2007 Physician United Kingdom
Primary
Concomitant
Oedema Hospitalization 3/15/2006 80 Male 11/26/2007 Other Health Professional France
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/9/2007 65 Male 11/27/2007 Physician France
Primary
Secondary
Concomitant
Visual Disturbance 66 Female 10/22/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 10/18/2007 Male 198 lb 1/22/2008 Other Health Professional Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 2/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 10/1/2006 83 Male 11/29/2007 Consumer United States
Primary
Concomitant
Pain Hospitalization 6/12/2007 78 Female 12/3/2007 Consumer United States
Primary
Concomitant
Mouth Haemorrhage Other Serious 4/6/2007 75 Male 289 lb 12/5/2007 United States
Primary
Concomitant
Malaise Other Serious Male 179 lb 4/11/2008 Physician Germany
Primary
Secondary
Concomitant
Spinal Disorder Other Serious Male 179 lb 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 4/1/2008 63 Male 4/30/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 7/1/2003 Female 5/12/2008 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 4/29/2007 Male 143 lb 5/14/2008 Malaysia
Primary
Concomitant
Hypertension Hospitalization 10/24/2007 Female 154 lb 5/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 5/22/2008 Physician United States
Primary
Concomitant
Hallucination, Visual Hospitalization 9/6/2007 94 Female 193 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Urinary Incontinence Other Serious 8/29/2007 79 Male 180 lb 7/15/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 62 Male 7/28/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Rhodococcus Infection Hospitalization 8/12/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/5/2008 Male 249 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 68 Female 9/9/2008 Pharmacist Spain
Primary
Concomitant
Interacting
Oedema Hospitalization 3/15/2006 80 Male 9/23/2008 Other Health Professional France
Primary
Concomitant
Blood Parathyroid Hormone Increased Other Serious 9/5/2006 Female 159 lb 9/25/2008 Germany
Primary
Concomitant
Follicle Centre Lymphoma, Follicular Grade I, Ii, Iii Other Serious 6/2/2008 Female 150 lb 12/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/27/2008 Male 219 lb 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Infected Skin Ulcer Hospitalization 8/8/2008 12/14/2008 Physician Brazil
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 56 Male 1/8/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/5/2008 78 Male 1/9/2009 Pharmacist United States
Primary
Concomitant
Swelling Face Hospitalization 11/4/2008 84 Male 1/9/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 56 Male 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious Female 1/19/2009 Consumer Portugal
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 1/20/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Cytolytic Hepatitis Hospitalization 12/6/2008 82 Male 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 12/4/2008 46 Female 2/11/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 2/2/2009 80 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/9/2009 Consumer United Kingdom
Primary
Secondary
Oedema Mucosal Other Serious 62 Female 3/12/2009 Consumer Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 56 Male 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Temporal Arteritis Other Serious 12/20/2008 Female 220 lb 3/27/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 56 Male 4/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/26/2009 39 Male 4/15/2009 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 62 Female 4/15/2009
Primary
Secondary
Concomitant
Gastritis Other Serious 62 Female 4/16/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 84 Female 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 8/3/2008 62 Male 6/5/2009 Physician United States
Primary
Concomitant
Restlessness Other Serious 8/5/2009 69 9/23/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 1/30/2009 Physician United States
Primary
Concomitant
Somnambulism Other Serious 10/3/2009 53 Male 160 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 11/10/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/25/2009 Male 140 lb 12/11/2009 Physician United Kingdom
Primary
Concomitant
Swelling Face Hospitalization 8/13/2009 79 Male 12/14/2009 Consumer Germany
Primary
Concomitant
Peritonitis Bacterial Other Serious 6/20/2009 Male 173 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 1/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Myocardial Infarction Other Serious 9/19/2008 Male 1/22/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2009 64 Male 1/21/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Vasculitis Other Serious 1/31/2010 66 Male 325 lb 2/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 12/15/2009 69 Male 2/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious Male 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 9/7/2009 63 Male 173 lb 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 3/4/2010 Lawyer United States
Primary
Concomitant
Tooth Fracture Other Serious 10/3/2006 Male 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 81 Male 3/15/2010 Physician Netherlands
Primary
Concomitant
Acute Myocardial Infarction Other Serious 8/28/2009 Male 3/15/2010 Physician Austria
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2009 Male 3/16/2010 Physician Austria
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 10/3/2006 Male 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 9/7/2009 63 Male 173 lb 3/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/3/2006 Male 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/12/2008 73 Female 163 lb 4/6/2010 Physician Peru
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 3/1/2010 70 Male 4/7/2010 Other Health Professional France
Primary
Concomitant
Interacting
Post Procedural Haematoma Life Threatening 3/5/2010 55 Male 4/7/2010 Physician Canada
Primary
Concomitant
Drug Eruption Hospitalization 2/1/2010 77 Male 4/8/2010 Other Health Professional Italy
Primary
Concomitant
Post Procedural Haematoma Life Threatening 3/3/2010 55 Male 4/15/2010 Physician Canada
Primary
Concomitant
Diverticulitis Hospitalization 2/17/2010 60 Male 139 lb 4/21/2010 Physician Denmark
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 8/28/2009 82 Male 5/3/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 44 Male 179 lb 5/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Nausea Other Serious 81 Female 5/6/2010 Consumer United States
Primary
Secondary
Concomitant
Overdose Hospitalization 5/5/2010 Male 5/13/2010 Pharmacist United States
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 2/16/2010 61 Female 109 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/28/2008 48 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Vascular Insufficiency Other Serious 10/1/2007 77 Female 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 5/27/2010 6/7/2010 Physician France
Primary
Secondary
Concomitant
Bradycardia Hospitalization 9/25/2008 84 Male 152 lb 6/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/1/2008 74 Male 6/15/2010 Lawyer United States
Primary
Concomitant
Nephropathy Toxic Hospitalization 2/1/2010 34 Female 6/16/2010 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/18/2010 Physician France
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/19/2008 86 Male 6/21/2010 Consumer Switzerland
Primary
Concomitant
Paraesthesia Other Serious 6/11/2010 41 Female 6/23/2010 Other Health Professional Netherlands
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/24/2010 Physician France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 6/24/2010 Physician France
Primary
Secondary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 6/25/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/21/2009 68 Male 6/29/2010 Consumer Netherlands
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 12/15/2009 69 Male 9/10/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/28/2008 48 Female 309 lb 9/28/2010 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2008 36 Female 230 lb 9/14/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 78 Female 10/1/2010 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 10/12/2008 87 Female 185 lb 10/1/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 76 Female 10/8/2010 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 10/1/2008 87 Female 10/8/2010 Consumer Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/25/2010 79 Male 154 lb 10/12/2010 Other Health Professional Austria
Primary
Concomitant
Walking Aid User Other Serious 10/3/2006 73 Male 10/14/2010 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 9/11/2010 72 Male 10/20/2010 Other Health Professional France
Primary
Concomitant
Interacting
Dyspnoea Other Serious 9/28/2010 80 187 lb 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Haemostasis Death Male 10/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 9/23/2010 77 Male 434 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/15/2008 64 Female 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/28/2010 78 Male 194 lb 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 7/1/2007 56 Female 11/9/2010 Physician Germany
Primary
Concomitant
Neurotoxicity Hospitalization 6/1/2007 56 Female 11/9/2010 Physician Germany
Primary
Concomitant
Vomiting Other Serious 12/3/2007 78 Female 150 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Syncope Life Threatening 8/30/2010 95 Female 186 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/27/2010 76 Female 11/29/2010 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 1/1/2010 42 Female 11/30/2010 Other Health Professional Netherlands
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 12/1/2010 Other Health Professional United States
Primary
Concomitant
Haemoptysis Hospitalization 1/31/2010 66 Male 325 lb 10/28/2010 Pharmacist
Primary
Concomitant
Sensation Of Heaviness Hospitalization 8/1/2010 42 Female 12/7/2010 Other Health Professional Netherlands
Primary
Concomitant
Myocardial Infarction Life Threatening 11/11/2010 Male 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data