Cyclophosphamide combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastasis Other Serious 10/15/2001 60 Male 5/12/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2005 45 Female 139 lb 2/24/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/24/2006 Physician United Kingdom
Primary
Concomitant
Coronary Artery Disease Life Threatening 12/14/2004 61 Female 198 lb 6/2/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 7/18/2003 62 Male 175 lb 6/20/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/20/2003 62 Male 6/16/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2003 62 Male 175 lb 6/16/2006 United States
Primary
Secondary
Concomitant
Headache Hospitalization 6/19/2006 63 Female 159 lb 6/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/18/2003 62 Male 6/20/2006 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 12/14/2004 61 Female 198 lb 7/5/2006 Physician South Africa
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/4/2006 74 Female 7/12/2006 United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/4/2006 74 Female 7/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/3/2007 53 Male 179 lb 2/12/2007 Physician Israel
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Septic Shock Other Serious 73 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 73 Female 4/20/2007 United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 73 Female 4/20/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 73 Female 5/3/2007
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased 4/28/2007 69 Female 4/29/2007 United States
Primary
Concomitant
Vision Blurred Other Serious 7/8/2004 Male 7/25/2007 Physician Switzerland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/8/2004 Male 7/31/2007 Physician Switzerland
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 7/1/2007 67 Male 8/8/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/9/2007 Female 129 lb 9/14/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/9/2007 Female 129 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 7/8/2004 Male 9/28/2007 Physician Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 9/9/2007 Female 129 lb 10/1/2007 United States
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 7/1/2007 67 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 73 Female 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/11/2008 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 3/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/29/2008 Male 176 lb 3/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/28/2007 Female 120 lb 3/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/21/2007 Female 265 lb 4/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/8/2007 Female 120 lb 4/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Life Threatening 3/22/2008 Female 141 lb 5/7/2008 Physician Germany
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/8/2007 Female 179 lb 5/30/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/22/2008 69 Female 108 lb 6/13/2008 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/8/2007 Female 120 lb 7/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 6/26/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2008 Female 8/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/28/2007 Female 120 lb 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 8/11/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/17/2008 77 Female 176 lb 8/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 10/15/2001 60 Male 9/16/2008 United States
Primary
Secondary
Concomitant
Muscle Disorder Other Serious 28 Female 10/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 76 Female 10/20/2008 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Other Serious 9/17/2008 63 Male 168 lb 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased Life Threatening 6/11/2008 59 Male 174 lb 11/10/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2008 59 Male 174 lb 11/21/2008 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 76 Female 11/25/2008 Other Health Professional Belgium
Primary
Concomitant
Panic Attack Other Serious Male 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 71 Male 12/30/2008 Other Health Professional France
Primary
Concomitant
Febrile Neutropenia Other Serious 4/26/2008 Female 173 lb 1/2/2009 Physician Portugal
Primary
Concomitant
Pneumonitis Hospitalization Male 1/5/2009 Physician France
Primary
Concomitant
Pulmonary Toxicity Hospitalization 71 Male 1/9/2009 Other Health Professional France
Primary
Concomitant
Partial Seizures Other Serious 12/20/2008 64 Female 141 lb 1/27/2009 Physician Spain
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 12/10/2008 62 Male 116 lb 1/22/2009 Physician United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/3/2009 United Kingdom
Primary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/5/2009 United Kingdom
Primary
Concomitant
Leukoencephalopathy Death Female 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/11/2008 60 Male 176 lb 3/12/2009 Physician France
Primary
Concomitant
Bone Pain Hospitalization 12/28/2006 Female 3/18/2009 Physician Germany
Primary
Concomitant
Leukopenia Hospitalization 2/8/2007 Female 3/18/2009 Physician Germany
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/11/2008 60 Male 176 lb 3/16/2009 Physician France
Primary
Concomitant
Leukoencephalopathy Death 1/1/2008 64 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 8/24/2008 76 Female 3/19/2009 Other Health Professional Belgium
Primary
Concomitant
Bone Pain Hospitalization 12/28/2006 Female 4/1/2009 Physician Germany
Primary
Concomitant
Leukopenia Hospitalization 2/8/2007 Female 4/1/2009 Physician Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 3/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Infection Hospitalization 3/18/2009 Female 4/3/2009 Physician United Kingdom
Primary
Concomitant
Leukoencephalopathy Other Serious 4/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 163 lb 4/8/2009 Physician
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/21/2008 65 Male 4/9/2009 Physician Denmark
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 163 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/9/2009 Physician Portugal
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 164 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 84 Female 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Female 163 lb 4/27/2009 Physician
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2009 84 Female 163 lb 4/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Hospitalization 12/28/2006 Female 4/30/2009 Physician Germany
Primary
Concomitant
Ventricular Fibrillation Hospitalization 6/19/2008 58 Male 126 lb 4/27/2009 Physician Portugal
Primary
Secondary
Concomitant
Pain Hospitalization 3/27/2009 Female 164 lb 5/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 84 Female 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 5/8/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/29/2008 Male 176 lb 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 3/18/2009 Female 5/18/2009 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/13/2009 Male 168 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/30/2009 67 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Pleuropericarditis Hospitalization 5/9/2009 65 Female 6/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 5/19/2009 Male 6/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/20/2009 Male 6/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 3/18/2009 Female 7/2/2009 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/27/2009 Male 155 lb 6/29/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/29/2008 Male 176 lb 7/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/12/2009 Male 7/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Haemodynamic Instability Hospitalization 50 Female 176 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 4/30/2009 67 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 5/20/2009 66 7/22/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/19/2009 Male 156 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Fatigue Life Threatening 10/23/2008 60 Female 220 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 181 lb 8/4/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 7/19/2009 78 Male 156 lb 8/3/2009 United States
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 8/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 7/19/2009 Male 156 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 8/7/2009 Netherlands
Primary
Secondary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 8/12/2009 Netherlands
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 5/20/2009 66 8/19/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 4/15/2008 Male 201 lb 8/20/2009 United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/19/2009 Male 156 lb 8/19/2009 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 5/19/2009 Male 8/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemolysis Hospitalization 6/25/2009 59 Male 181 lb 10/14/2009 Physician Netherlands
Primary
Secondary
Concomitant
Angioedema Hospitalization 28 Female 10/20/2009 Other Health Professional South Africa
Primary
Concomitant
Angioedema Hospitalization 28 Female 10/26/2009 Other Health Professional South Africa
Primary
Concomitant
Proteinuria Hospitalization 28 Female 10/19/2009 Physician South Africa
Primary
Concomitant
Urticaria Other Serious 9/1/2009 Male 10/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 9/1/2009 Female 145 lb 10/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Angioedema Hospitalization 28 Female 11/3/2009 Other Health Professional South Africa
Primary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 2/6/2008 Female 11/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/25/2009 69 12/14/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/16/2009 Physician Australia
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 2/6/2008 Female 143 lb 12/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 12/21/2009 Female 153 lb 12/22/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/25/2008 Female 194 lb 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/1/2007 63 Male 1/8/2010 Lawyer United States
Primary
Concomitant
Respiratory Distress Other Serious 11/1/2009 72 Male 1/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant

Drug Data